• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
ADHD drugs compared - Consumer Health Choices
ADHD drugs compared - Consumer Health Choices

... These medicines don’t cure ADHD but they can reduce symptoms, such as hyperactivity and impulsivity, which might improve a person’s daily functioning. However, there is uncertainty about whether these benefits last for longer than two years, so you might want to periodically discuss with your physi ...
pediatric sedation - respiratorytherapyfiles.net
pediatric sedation - respiratorytherapyfiles.net

... procedure and/or administration of moderate or deep sedation or anesthesia. Each patient’s physiological status, mental status, and pain level are monitored Monitoring is at a level consistent with the potential effect of the procedure and/or sedation or anesthesia. Patients are discharged from the ...
Lovastatin and beyond
Lovastatin and beyond

... Anitschkow and Chalatow showed that feeding cholesterol to rabbits rapidly produces atheromatous disease similar to that found in man. However, physicians were sceptical of any causal link between cholesterol and CORONARY HEART DISEASE (CHD) because most patients with the disease have plasma cholest ...
Effects of a structured medical management intervention aimed at
Effects of a structured medical management intervention aimed at

... At T1 medication complexity was statistically significantly lower in the intervention than in the control group. This effect was partly reversed at T2 to statistically non-significant values. Propensity adjusted complete adherence rates at discharge and six weeks after discharge were slightly higher ...
Using the type 2 diabetes glycemic treatment
Using the type 2 diabetes glycemic treatment

... select treatments that are most likely to help the patient achieve the goal. • It includes recommendations on when to use DPP-4 inhibitors and when oral 3-drug combinations are appropriate. ...
Chemistry for Changing Times 11th Edition Hill and Kolb
Chemistry for Changing Times 11th Edition Hill and Kolb

... Newer NSAIDs only block the COX-2 enzyme and do not experience the side effects of the older NSAIDs. Unfortunately, some have side effects of increased risks of heart attack and stroke as well as allergic reactions and internal bleeding. ...
nsaids
nsaids

... activity. Most act primarily by inhibiting cyclo-oxygenase leading to reduced synthesis of prostaglandins and related compounds. This mechanism probably underlies their principal therapeutic and toxic activities. However, many studies have shown a number of additional actions, including inhibition o ...
Prodrugs for Amines
Prodrugs for Amines

... An example of this is the tendency of primary amines to undergo first-pass metabolism due to Nacetylation and oxidation by monoaminooxidase (MAO) [1]. The same applies to peptides [2] containing basic amino acid side-chains. Low water solubility, poor stability and low permeability through biologica ...
Ambiguity aversion and familiarity bias
Ambiguity aversion and familiarity bias

... traits and behaviors of interest, referred to as phenotypes, are far downstream from the gene expression. While in some cases a single change in one letter of the DNA alphabet in a single gene alone can lead to a disease (such as sickle cell anemia), the vast majority of phenotypes are polygenic, me ...
Biology CLIL lesson Mendel`s work
Biology CLIL lesson Mendel`s work

... Mendel concluded that the F1 plants must contain 2 distinct factors, one for each character. The character that was seen in the F1 is called DOMINANT. The character that was not seen in the F1 is called RECESSIVE. The characteristics studied by Mendel were due to single genes. By convention, upper c ...
Focus on Lisdexamfetamine: A Review of its use in Child and
Focus on Lisdexamfetamine: A Review of its use in Child and

... occurs via hydrolytic enzymes located on erythrocytes, and leads to an onset of action within 1-2 hours post-dose, and duration of up to 13 hours. Administration of lisdexamfetamine via nasal or intravenous routes did not result in significant elevation of drug liking scores in known stimulant abuse ...
Indonesia - K4Health
Indonesia - K4Health

... labor in the vast majority of facility-based deliveries in the sample, with oxytocin used in almost all of deliveries. Use of AMTSL according to the ICM/FIGO definition was observed in 32 percent of deliveries. If the definition of AMTSL is relaxed to allow for administration of the uterotonic drug ...
Evaluation of Dependence and Withdrawal in Clinical Trials
Evaluation of Dependence and Withdrawal in Clinical Trials

... • 1) recurrence of symptoms of the treated disorder in patients, sometimes more severe (This would be one important reason to evaluate dependence in healthy subjects) ...
Muscle Relaxant Property of 1(4-carboxy phenyl)- 4,4,6-trimethyl
Muscle Relaxant Property of 1(4-carboxy phenyl)- 4,4,6-trimethyl

... phenobarbitone. Material and Methods: Spasmolytic activity of 4CPTP was studied using rabbit ileum and guinea pig ileum preparation. Skeletal muscle relaxant activity was assessed on frog rectus abdominis preparation. Mean height of contractions with graded doses of phenobarbitone and 4CPTP along wi ...
Mendel and Punnet Square Quiz - etec-510-2011
Mendel and Punnet Square Quiz - etec-510-2011

... 15. Which of the following is an example of homozygous dominant genotype? a) height gene b) short gene c) TT d) tt Formative feedback a) We don’t know if height is a dominant or recessive gene without looking at the alleles. b) We don’t know if being short is a dominant or recessive gene without loo ...
Consent for treatment with Buprenorphine
Consent for treatment with Buprenorphine

... Some patients find that it takes several days to get used to the transition from the opiate they had been using to buprenorphine. During that time, any use of other opiates may cause an increase in symptoms. After you become stabilized on buprenorphine, it is expected that other opiates will have le ...
Baptist Health South Florida Neonatal Moderate Sedation and
Baptist Health South Florida Neonatal Moderate Sedation and

... The American Society of Anesthesiology (ASA) has developed a classification system for patients in order to aid in the risks of sedation. This classification categorizes patients on a general health basis prior to receiving anesthesia. It is one of the most important factors used to assess the overa ...
30 Years of SLIT:
30 Years of SLIT:

... Copyright 2015 Allergy Associates of La Crosse ...
Buccal Drug Delivery Systems: Opportunities And Challenges In Buccal,
Buccal Drug Delivery Systems: Opportunities And Challenges In Buccal,

... Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. The mucosa has a rich blood supply and it is relatively permeable. The buccal mucosa offers several advantages for controlled drug delivery for extended periods of time. The muc ...
Primary endpoints
Primary endpoints

... Current guidelines: 12 months DAPT (derived primarily from clinical experience… and the use of stent in ACS) ...
Use of digoxin in older patients
Use of digoxin in older patients

... In the treatment of worsening of systolic heart failure important role maintains digoxin. In the management of older patients it is important to take into account age-related changes of pharmacokinetics and pharmacodynamics, decreased glomerular filtration rate, sex and concomitant diseases. Older i ...
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   
FORMULATION OF RAPID MOUTH DISSOLVING TABLETS OF CETIRIZINE di HCL USING  SUBLIMATION METHOD  Research Article   

... oven5 at 600mm Hg at 800C for 1 hour.  Evaluation  For  weight  variation  study,  twenty  tablets  were  weighed  individually  before  and  after  sublimation  and  from  the  average  weight,  standard  deviation  was  determined.  The  crushing  strength  (Kg/cm 2)  of  prepared  tablets  was  m ...
Smoking Cessation in Psychiatric Patients
Smoking Cessation in Psychiatric Patients

... monoxide and other harmful substances is eliminated. Clinicians should also conduct a careful risk-benefit analysis of prescribing versus notprescribing NRT. ...
Management of PUD, H. pylori infection
Management of PUD, H. pylori infection

... GI bleed & ulceration can occur with NSAIDs. If possible withdraw NSAID if ulceration. Consider alternative analgesia ...
Genomics-based approaches to improve drought tolerance of crops
Genomics-based approaches to improve drought tolerance of crops

... selected for high-input environments where water supply is often not a major limiting factor, wild species show morpho-physiological features for survival and adaptation to drought conditions. When considering exploiting alleles from wild species for drought-adaptive features, a careful evaluation i ...
< 1 ... 181 182 183 184 185 186 187 188 189 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report