• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
POSTOPERATIVE PAIN MANAGEMENT
POSTOPERATIVE PAIN MANAGEMENT

... renal or hepatic insufficiency or other conditions affecting drug metabolism and kinetics. ...
Introduction to Genome-Wide Association Studies
Introduction to Genome-Wide Association Studies

... • Genome-Wide Association Study – study interrogating the relationship between genome-wide genetic variation and a phenotype. ...
Process of Evolution - Woodstown
Process of Evolution - Woodstown

... States: equilibrium of allele frequencies in a gene pool will remain in effect in each generation of sexually reproducing populations as long as: ...
Efavirenz Risk List
Efavirenz Risk List

Therapeutic Drug Monitoring
Therapeutic Drug Monitoring

... • Drugs with low Vd are contained mostly in the plasma, because . . . – They are highly water soluble (plasma water content is higher than tissues), or – They are highly protein bound (which prevents them from freely diffusing into tissues ...
Express Results™ Online
Express Results™ Online

... designed to deliver fast, dependable results Employers depend on reliable drug testing results to help them make informed hiring and staffing decisions. When turnaround time is of the essence, Express Results™ Online provides a fast, accurate, electronically-driven drug testing solution. Negative dr ...
It Wasn`t Like That When I Was a Teen!
It Wasn`t Like That When I Was a Teen!

...  Heroin is a highly addictive drug derived from morphine. It is a “downer” or depressant that affects the brain’s pleasure systems and interferes with the brain’s ability to perceive pain.  Potency: 5% in the 70’s – today – 50-80% pure  Higher potency allows for snorting or smoking it to achieve ...
May 2007, Number 5  - UF Health Professionals
May 2007, Number 5 - UF Health Professionals

... alternate treatments and that patients should not stop taking the medication, as stopping pergolide abruptly can be dangerous (ie, precipitating central nervous adverse effects including confusion and hallucinations). There are alternative therapies available for Parkinson’s disease, including other ...
03-Lecture_3 pharma2008-10-31 07:3789 KB
03-Lecture_3 pharma2008-10-31 07:3789 KB

... Coupled to g-protein :  Interaction with guanine nucleotide GDP , GTP .  Comprise of 3 subunits (α,β,γ) .. α subunits possess GTPase activity .  drug makes conformational change of receptor>>> increase affainity for trimen>>> dissociation of a subunit (GTP) complex (active)>>> activation of chann ...
mg/kg/day
mg/kg/day

Drug Facts Label Powerpoint
Drug Facts Label Powerpoint

... worse or lasts more than 3 days ■redness or swelling is present ...
Society of Nuclear Medicine
Society of Nuclear Medicine

... 7.  Are there other state regulations regarding compounded preparations?  If so, these must be  followed.  For example, some state boards of pharmacy require the patient to be informed  that he/she is receiving a compounded preparation.  ...
thiazide diuretics - Christchurch Drug Information Service
thiazide diuretics - Christchurch Drug Information Service

... There are four single-ingredient thiazide (or thiazide-like) preparations in New Zealand: bendrofluazide, chlorthalidone, cyclopenthiazide and indapamide. We are not aware of any data describing the transfer of bendrofluazide, cyclopenthiazide or indapamide into human breast milk[1,3,6] . There are ...
Disclosures Objectives: Pharmacists Objectives: Pharmacy
Disclosures Objectives: Pharmacists Objectives: Pharmacy

... o I will be discussing off-label use of medications ...
Introduction to Pharmacy Practice
Introduction to Pharmacy Practice

...  use of technicians to record laboratory results  screening orders for non-formulary status  identifying orders on the hospital’s restricted list  review & collect missing information for patient ...
Slides for Chapter 6a
Slides for Chapter 6a

... Enzyme Active Site ...
Slide 1
Slide 1

... • Cells which have the same X chromosome inactivated tend to group together in adult females, forming patches. • This means that different patches of the body will express different phenotypes. ...
Article 07-10: Carcinogenicity of Lipid-lowering Drugs
Article 07-10: Carcinogenicity of Lipid-lowering Drugs

... Inadequate response to weight loss, diet, and exercise. “Unfortunately, the subsequent popularity of gemfibrozil suggests that its use has not been restricted to this small group.” “For patients not at high short-term risk of CHD death, especially patients with life expectancies of more than 10 to 2 ...
Antianxiety, Mood Disorder and Antipsychotic Medications
Antianxiety, Mood Disorder and Antipsychotic Medications

... Mild s/s occur in approximately half of clients taking doses for 6-12 weeks or longer Severe s/s if taking large doses for 4 months or longer and with abrupt discontinuation Affects are r/t decrease in GABA neurotransmission resulting in CNS ...
quiz_-_chapter_5
quiz_-_chapter_5

... Quiz: Chapter 5 (Genetics and Inheritance Patterns) True or False. Write T if the statement is true, F if it is false. If false, correct the underlined word. ...
Opiates: Good or Bad?
Opiates: Good or Bad?

... Opiates are difficult to synthesize due to the complex structures. Oxycodone is a semisynthetic opioid analgesic made from the precursor thebaine in opium poppy. The complete synthesis of oxycodone is “complicated and in low yield”; therefore, it is semisynthetically produced from thebaine [11]. Alt ...
Mood Stabilisers
Mood Stabilisers

...  Cyclic adenosine monophosphate (cAMP)  intracellular signal transduction  A different process of neurotransmission ...
System-Wide Medication Related Decision Evaluation
System-Wide Medication Related Decision Evaluation

...  Effective May 19, 2015, codeine became no longer orderable for patients under 18 in Providence Epic acute settings, including the ED. Safer alternatives will be displayed when codeine is ordered in this population. Swedish Epic does not currently have an interchange built and is reviewing to deter ...
CAREMARK
CAREMARK

... Reducing signs and symptoms and inducing and maintaining clinical remission in adult patients with moderately-toseverely active Crohn’s disease who have had an inadequate response to conventional therapy; also for reducing signs and symptoms and inducing clinical remission in these patients if they ...
Personalized Medicine
Personalized Medicine

... The results in 2013 • The most drugs are not or partially effective in the 60% of the treated patients • Side effects are responsible for – 100,000 death – 2 million hospitalisations – 100 billion USD cost for healthcare in USA – 50%- of the cases is related genetics ...
< 1 ... 1103 1104 1105 1106 1107 1108 1109 1110 1111 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report