• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
a55f476935070a0
a55f476935070a0

... eliminated from the body through hepatic metabolism less than 5% of the drug is eliminated by the renal ...
Section 7.1: Chromosomes and Phenotype
Section 7.1: Chromosomes and Phenotype

Antimicrobial Resistance — A New Drug Discovery Perspective
Antimicrobial Resistance — A New Drug Discovery Perspective

... with new developments usually being based on derivatives of existing antibiotics. Only two new antibiotics entered the market in the last decade: telavancin, which was approved by the Food and Drug Administration (FDA) in September 2009, is a vancomycin derivative; and ceftaroline, approved in Octob ...
Mini Course on Pharmacovigilance
Mini Course on Pharmacovigilance

... n  Intensive medicines monitoring program n  Clinical trials at various phases ...
Gene Expression - CS
Gene Expression - CS

club drugs - Florida Alcohol and Drug Abuse Association
club drugs - Florida Alcohol and Drug Abuse Association

... But in the past few years, these drugs have been found increasingly in more mainstream settings. Due to the uncertainty of their sources (i.e. pharmacological agents, chemicals used to manufacture them, and contaminants) it is often difficult to determine symptoms, toxicity, and consequences of usin ...
here - Nordgen
here - Nordgen

... A gene bank is a collection of seeds and other plant reproductive material, primarily of cultivated plants and their wild relatives. These collections represent as far as possible the gene pools of our crop plants, that is, the genetic basis of agriculture and horticulture. The mandate of a gene ban ...
Inheritance
Inheritance

... “We know what we are, but we know not what we may be.” - Ophelia, in Shakespeare’s Hamlet In this unit, we will address the following Maine Learning Results standards: A2a: compare different types of models that can be used to represent the same thing, in order to match the purpose and complexity of ...
Table of Antidotes (Word Document, 20kB)
Table of Antidotes (Word Document, 20kB)

... formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin. ...
? RHEUMATOID ARTHRITIS .– DEFERRED
? RHEUMATOID ARTHRITIS .– DEFERRED

... review of this product is currently being undertaken and that other countries have identified safety concerns which have led to suspension of sales of MERIDIA in one instance. The Committee advised that with evidence of benefit of only short-term weight loss, lack of cardiovascular outcome or morbid ...
EP5.2.2 Renal Transplant Council Meeting Minutes
EP5.2.2 Renal Transplant Council Meeting Minutes

... the computer assigned a due time of 9:00 a.m. the next day. The night nurse gave the drug that night but “stole” the 9:00 a.m. dose when he/she charted on the eMAR. As a result, the 9:00 a.m. dose did NOT pink up and was thus missed. 3. Severity 1, Med-Tele. Drug: Cyclosporin suspension This was a d ...
TheraGuide 5-FU
TheraGuide 5-FU

... • The study of genetic variation that determines an individual’s response to drugs • Pharmacogenetic testing can be beneficial in oncology because it can help determine – How a patient will respond to chemotherapy • Example: cytochrome P450 2D6 (CYP2D6) genotype and ability to metabolize tamoxifen ...
Gero-Rehab Course
Gero-Rehab Course

... anemia, aplastic anemia, eosinophilia, hemolytic anemia, leukopenia, neutropenia, pancytopenia, prolonged ...
A Primer on Genetics Research with
A Primer on Genetics Research with

... It is difficult to know what benefits our participants will get from the study because biomedical technology continues to advance rapidly. At a minimum, identifying the specific genes that contribute to increasing risk for these diseases could be used to help identify people who may be at greatest r ...
amoxicillin/clavulanate - DavisPlus
amoxicillin/clavulanate - DavisPlus

... sorption and to decrease GI side effects. Do not administer with high fat meals; clavulanate absorption is decreased. XR tablet is scored and can be broken for ease of administration. Capsule contents may be emptied and swallowed with liquids. Chewable tablets should be crushed or chewed before swal ...
Practice Exam for Pharmacology Exam 1 – Lectures 1
Practice Exam for Pharmacology Exam 1 – Lectures 1

False negative for hydrocodone
False negative for hydrocodone

... Learn What Is A False Positive Drug Test Is. Search A Comprehensive List Of What Medications, Prescriptions And Foods Can Cause A False Drug Test. Find out which drugs can potentially cause a false positive drug test including additional details on the more commonly used substances. Hydrocodone drug ...
Lysergic Acid Diethylamide (LSD)
Lysergic Acid Diethylamide (LSD)

... LSD has always been something of a young person's drug, and today, its being taken by even younger individuals. A growing percentage of high school students are reporting using LSD at least once. OTHER DRUGS IN THE SAME CLASS: Mushrooms: Also known as: Shrooms and Magic Mushrooms. Psilocybin is the ...
Selected module tests in Pharmacology
Selected module tests in Pharmacology

... 16. The main way of enteral administration of drugs is: A. Oral. B. By injection. C. Rectal. D. Permucоus. 17. Point out the incorrect statement: A. The drug distribution in the organism depends on the way they are applied, their pK and organ perfusion. B. AUC means “area under the curve” time/conce ...
genetic drift
genetic drift

... are less important and include: Mutations and Gene Flow. These two forces provide less of a change in a population because Mutation is very rare and Gene Flow tends to equalize gene frequencies between populations (which tends to slow down change). Natural Selection occurs because organisms with fav ...
Regulation, Reimbursement, and the Long Road of
Regulation, Reimbursement, and the Long Road of

... payers want to know how effective the test is compared with alternative tests (if available) or interventions and preferably so in the real world, that is, the environment in which reimbursement decisions are actually being made. Ultimately, clinical outcomes are affected by more factors than the on ...
Racial and Ethnic Differences in Response to Medicines
Racial and Ethnic Differences in Response to Medicines

... the Medicaid population and with “bare bones” health plans sets the stage for health care disparities in the statutory use of “therapeutically equivalent,” but untested, generic drugs within this group. This typifies what is referred to in the 2002 IOM report as the socioeconomic fragmentation of he ...
Safe Swallowing of Oral Liquid Medications in Patients with Dysphagia
Safe Swallowing of Oral Liquid Medications in Patients with Dysphagia

Chapter_1:introduction to medicinal chemistry
Chapter_1:introduction to medicinal chemistry

... Is it food, drug or poison ? • Drugs act by interfering with biological processes, so no drug is completely safe. • Food can act like a drug. Junk foods and fizzy drinks have been blamed for causing hyperactivity in children. It is believed that junk foods have high concentrations of certain amino ...
djimbe
djimbe

... Table III. – Evolution of clinical and parasitological symptoms in each group of patients included in the comparative efficacy trial. Parasite, 2005, 12, 73-77 ...
< 1 ... 1049 1050 1051 1052 1053 1054 1055 1056 1057 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report