
SilkDB: a knowledgebase for silkworm biology and genomics
... The Silkworm Knowledgebase (SilkDB) is a webbased repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a 6X draft genome sequence of the domestic silkworm (Bombyx mori ), SilkDB provides an integrated representation of the large- ...
... The Silkworm Knowledgebase (SilkDB) is a webbased repository for the curation, integration and study of silkworm genetic and genomic data. With the recent accomplishment of a 6X draft genome sequence of the domestic silkworm (Bombyx mori ), SilkDB provides an integrated representation of the large- ...
CHANGES TO THE GENETIC CODE
... Changes that build up in the genes in our body cells during our lifetime cannot be passed on to our children Changes to the DNA can be due to exposure to radiation such as that produced by the sun or by certain chemicals in our diets and in our external environment. Changes may also occur in our DNA ...
... Changes that build up in the genes in our body cells during our lifetime cannot be passed on to our children Changes to the DNA can be due to exposure to radiation such as that produced by the sun or by certain chemicals in our diets and in our external environment. Changes may also occur in our DNA ...
Gene Flow Up to now, we have dealt with local populations in which
... populations of inbreeding effective size Nef are experiencing gene flow at a rate of m per generation. Then, what is the probabilty that two randomly drawn genes from the same subpopulation are identical by descent AND from the same population? That is, if one of the genes came from the other gene p ...
... populations of inbreeding effective size Nef are experiencing gene flow at a rate of m per generation. Then, what is the probabilty that two randomly drawn genes from the same subpopulation are identical by descent AND from the same population? That is, if one of the genes came from the other gene p ...
Letter Detecting Sequence Homology at the
... encoded by genes that are physically clustered together on the chromosome in operons or gene clusters (Fischbach and Voigt 2010). The architectures of these gene clusters are sometimes well-conserved between species, but they may also evolve quickly through rearrangements, insertions, deletions, and ...
... encoded by genes that are physically clustered together on the chromosome in operons or gene clusters (Fischbach and Voigt 2010). The architectures of these gene clusters are sometimes well-conserved between species, but they may also evolve quickly through rearrangements, insertions, deletions, and ...
Baldness genetics – more than skin deep. Stephen B Harrap The
... The mystery, and the potential for fundamental biological discovery, is why front hair should vanish, while that at the back of the head should flourish. Presumably genetic predisposition alters expression of key genes in a regionally specific manner to cause patterned hair loss. But what genes are ...
... The mystery, and the potential for fundamental biological discovery, is why front hair should vanish, while that at the back of the head should flourish. Presumably genetic predisposition alters expression of key genes in a regionally specific manner to cause patterned hair loss. But what genes are ...
Copies of Student Information pages
... We are complex beings made up of thousands of characteristics (traits). The “blueprint” for all of these traits is in our chromosomes. Chromosomes are made of DNA (deoxyribonucleic acid) and proteins. They are found in the nucleus of every body cell, except red blood cells. Red blood cells do not co ...
... We are complex beings made up of thousands of characteristics (traits). The “blueprint” for all of these traits is in our chromosomes. Chromosomes are made of DNA (deoxyribonucleic acid) and proteins. They are found in the nucleus of every body cell, except red blood cells. Red blood cells do not co ...
Exercise - GEP Community Server - Washington University in St. Louis
... and 3’ end columns in the table show the coordinates of exons on the D. melanogaster chromosome. Clicking on each exon in the exon table, reveals the sequence that corresponds to the selected exon. In order to generate a gene model, we will use both polypeptide and transcript details. In this simple ...
... and 3’ end columns in the table show the coordinates of exons on the D. melanogaster chromosome. Clicking on each exon in the exon table, reveals the sequence that corresponds to the selected exon. In order to generate a gene model, we will use both polypeptide and transcript details. In this simple ...
Molecular Coat Colour Genetics
... genes, which raises the possibility of a mechanism akin to exon shuffling. Therefore, such chromosomal rearrangements as duplications are considered as exclusive contributors to the origin of reproductive isolation and the formation of new species (Lynch, 2002). Moreover, it has been proposed that ...
... genes, which raises the possibility of a mechanism akin to exon shuffling. Therefore, such chromosomal rearrangements as duplications are considered as exclusive contributors to the origin of reproductive isolation and the formation of new species (Lynch, 2002). Moreover, it has been proposed that ...
Article - Nature
... PhzH-Pa,5 and PhzH-Pc6 had been evaluated for their function in secondary metabolite syntheses in vivo. Only NspN2 and PcsB6 had also been characterized in vitro. In contrast, ORF5,8 SioC, ORF1,9 SfaP, TcsG, FdmV,10 SanV,11 and LlpA12 had not yet been fully characterized. Their involvement in second ...
... PhzH-Pa,5 and PhzH-Pc6 had been evaluated for their function in secondary metabolite syntheses in vivo. Only NspN2 and PcsB6 had also been characterized in vitro. In contrast, ORF5,8 SioC, ORF1,9 SfaP, TcsG, FdmV,10 SanV,11 and LlpA12 had not yet been fully characterized. Their involvement in second ...
Help - H-Invitational database!!
... Mapping Info. with all EST, ens_gene and ref_gene by UCSC Orthologous genes of other species Repeat, SNPs, microsatellite, ACC#, ID search Hyperlinks to other databases Gene structures for 11 species; Mouse, Rat, Chimpanzee, etc ...
... Mapping Info. with all EST, ens_gene and ref_gene by UCSC Orthologous genes of other species Repeat, SNPs, microsatellite, ACC#, ID search Hyperlinks to other databases Gene structures for 11 species; Mouse, Rat, Chimpanzee, etc ...
World`s first ge - Ottawa Health Research Institute
... many twists and turns. One of these is the fact that Dr. Worton's team identified the gene in a girl, while DMD almost always affects boys. The reason for this has to do with our chromosomes – the structures that contain all our genes, arranged in a defined order. Humans have two copies of each chro ...
... many twists and turns. One of these is the fact that Dr. Worton's team identified the gene in a girl, while DMD almost always affects boys. The reason for this has to do with our chromosomes – the structures that contain all our genes, arranged in a defined order. Humans have two copies of each chro ...
Gene: Fine Structure of Gene
... Composite transposons may help bacteria adapt to new environments. Repeated movements of resistance genes by composite transposition may concentrate several genes for antibiotic resistance onto a single R plasmid. Nevertheless, there exist another sort of transposons, called unit transposons, ...
... Composite transposons may help bacteria adapt to new environments. Repeated movements of resistance genes by composite transposition may concentrate several genes for antibiotic resistance onto a single R plasmid. Nevertheless, there exist another sort of transposons, called unit transposons, ...
File
... map showing the relative locations of each known gene on one of the Drosophila chromosomes, as shown in Figure 11–19. If two genes are close together, the recombination frequency between them should be low, since crossovers are rare. If they are far apart, recombination rates between them should be ...
... map showing the relative locations of each known gene on one of the Drosophila chromosomes, as shown in Figure 11–19. If two genes are close together, the recombination frequency between them should be low, since crossovers are rare. If they are far apart, recombination rates between them should be ...
Filtering Restriction Fragment Size on Affymetrix SNP Arrays
... Filtering Restriction Fragment Size on Affymetrix SNP Arrays for Copy Number or LOH Analysis using Partek Genomics Suite for use with FFPE Samples Overview Many samples available to medical researchers are Formalin-Fixed, ParaffinEmbedded (FFPE). However, this storage method can increase the rate of ...
... Filtering Restriction Fragment Size on Affymetrix SNP Arrays for Copy Number or LOH Analysis using Partek Genomics Suite for use with FFPE Samples Overview Many samples available to medical researchers are Formalin-Fixed, ParaffinEmbedded (FFPE). However, this storage method can increase the rate of ...
MMG 232: Methods In Bioinformatics Spring 2016, 3 credits
... BLAST searches and Protein visualization Amplicon sequencing & OTU identification Inferring evolutionary history Metagenomics: the complete picture What have you learned so far? Structural changes & DNA integration: inversion/translocation & viral insertion The effects of differential gene expressio ...
... BLAST searches and Protein visualization Amplicon sequencing & OTU identification Inferring evolutionary history Metagenomics: the complete picture What have you learned so far? Structural changes & DNA integration: inversion/translocation & viral insertion The effects of differential gene expressio ...
Sex chromosome-to-autosome transposition - David Page Lab
... highly differentiated: the Y chromosome is dramatically smaller than the X and has lost most of its genes. The surviving genes are a specialized set with extraordinary evolutionary longevity. Most mammalian lineages have experienced delayed, or relatively recent, loss of at least one conserved Y-lin ...
... highly differentiated: the Y chromosome is dramatically smaller than the X and has lost most of its genes. The surviving genes are a specialized set with extraordinary evolutionary longevity. Most mammalian lineages have experienced delayed, or relatively recent, loss of at least one conserved Y-lin ...
Document
... body weight analysis of YG22R and YG8R demonstrated an increase in weight compared to B6 GAA repeat instability in the brain and cerebellum of both YG22 and YG8 transgenic mice Consistent reduction in the levels of frataxin mRNA and protein in the brain and liver samples of YG8R and YG22R mice compa ...
... body weight analysis of YG22R and YG8R demonstrated an increase in weight compared to B6 GAA repeat instability in the brain and cerebellum of both YG22 and YG8 transgenic mice Consistent reduction in the levels of frataxin mRNA and protein in the brain and liver samples of YG8R and YG22R mice compa ...
Class VII Using cloned DNA fragments to study gene expression 1
... These differences among genes can be primarily of two types: A. Differences in the sequence of the same gene present in two different individuals or organisms. (These can be alleles or mutations) B. The “activity” of the same gene might be different in two different individuals (or tissues or organ ...
... These differences among genes can be primarily of two types: A. Differences in the sequence of the same gene present in two different individuals or organisms. (These can be alleles or mutations) B. The “activity” of the same gene might be different in two different individuals (or tissues or organ ...
Heredity Quiz 2017 Self-Testing Guide DUE day of quiz! ANSWERS
... Genes and Dominance-. Remember when we learned about trait inheritance and dominance by putting leaves on a tree and created adorable baby caterpillars to practice our knowledge of the 4 rules of inheritance, 5. Who are your genes inherited from? Our genes are inherited from our parents. We receive ...
... Genes and Dominance-. Remember when we learned about trait inheritance and dominance by putting leaves on a tree and created adorable baby caterpillars to practice our knowledge of the 4 rules of inheritance, 5. Who are your genes inherited from? Our genes are inherited from our parents. We receive ...
Supplementary Note
... the same libraries with tammar SOX3 yielded many positive clones, but these proved to contain either unrelated sequences, or SOX genes that were present in both sexes. Two platypus SOXB genes (SOX2 and SOX14) were characterized and mappedS9. The strategy that was ultimately accepted for demonstratin ...
... the same libraries with tammar SOX3 yielded many positive clones, but these proved to contain either unrelated sequences, or SOX genes that were present in both sexes. Two platypus SOXB genes (SOX2 and SOX14) were characterized and mappedS9. The strategy that was ultimately accepted for demonstratin ...
Document
... benefitted if animals are developed that can withstand hypoxic stress. It would also be important to know if this gene has any relationship with growth, to determine whether normal growth is affected during prolonged periods of hypoxia. HIF-1α has been widely studied in various mammalian and fish sp ...
... benefitted if animals are developed that can withstand hypoxic stress. It would also be important to know if this gene has any relationship with growth, to determine whether normal growth is affected during prolonged periods of hypoxia. HIF-1α has been widely studied in various mammalian and fish sp ...
An intron nucleotide sequence variant in a
... the pre-mRNA. Unfortunately experimental data on the mechanism of intron excision is insufficient to predict whether or not this particular G-»A replacement could cause ineffective pre-mRNA processing. In two studies insertions or deletions made in intron sequences had no apparent effect on gene tra ...
... the pre-mRNA. Unfortunately experimental data on the mechanism of intron excision is insufficient to predict whether or not this particular G-»A replacement could cause ineffective pre-mRNA processing. In two studies insertions or deletions made in intron sequences had no apparent effect on gene tra ...
Leukaemia Section t(5;11)(q35;q12) NSD1/FEN1 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... The protein has 380 amino acids and localizes to the nucleus. It is a structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. It acts as a genome stabilization factor that prevents flaps from equilibrating into structures that le ...
... The protein has 380 amino acids and localizes to the nucleus. It is a structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. It acts as a genome stabilization factor that prevents flaps from equilibrating into structures that le ...
Copy-number variation

Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.