Gene sequencing Terms
... • Polymorphism meaning “non-disease-causing change” or “change found at a frequency of 1% or higher in the population”. ...
... • Polymorphism meaning “non-disease-causing change” or “change found at a frequency of 1% or higher in the population”. ...
Endogenous retroviruses: Still active after all
... for the host. Some stem from the insertion of multiple copies of DNA sequences containing signals capable of modifying transcription or RNA processing. Thus proviruses might act to cause chromosomal rearrangement by homologous recombination, as a source of novel control sequences for cellular genes ...
... for the host. Some stem from the insertion of multiple copies of DNA sequences containing signals capable of modifying transcription or RNA processing. Thus proviruses might act to cause chromosomal rearrangement by homologous recombination, as a source of novel control sequences for cellular genes ...
Color Inheritance in the Brittany
... orange Brittanys we see a disproportionately large amount compared to the liver variety. Part of this has to do with the selection process, orange being more popular than liver, but some of it can be explained by pure chance. When two orange dogs are bred together, they will always produce only oran ...
... orange Brittanys we see a disproportionately large amount compared to the liver variety. Part of this has to do with the selection process, orange being more popular than liver, but some of it can be explained by pure chance. When two orange dogs are bred together, they will always produce only oran ...
CGC07OthrGene - Cucurbit Breeding
... and bitter melon (Momordica charantia. They have fruit that are used for food, decoration, containers, utensils or sponges. The exception is Melothria, which has medicinal uses (Iman et al, 2006). Gene List Update The following list is the latest version of the gene list for the miscellaneous specie ...
... and bitter melon (Momordica charantia. They have fruit that are used for food, decoration, containers, utensils or sponges. The exception is Melothria, which has medicinal uses (Iman et al, 2006). Gene List Update The following list is the latest version of the gene list for the miscellaneous specie ...
The Title of the Article
... from text descriptions of genes and uses them to relate genes close to disease-associated loci. The keywords common to pairs of gene descriptions may represent preliminary hypotheses about the biological relationship between the genes, and the role the genes play in the disease phenotype. We discuss ...
... from text descriptions of genes and uses them to relate genes close to disease-associated loci. The keywords common to pairs of gene descriptions may represent preliminary hypotheses about the biological relationship between the genes, and the role the genes play in the disease phenotype. We discuss ...
Finding the wheat homologues of genes from model organisms
... model or non-model plant species. This is especially usefully in translational research or comparative genomic studies where the gene of interest might have been well characterised in a model species (like Arabidopsis) and it is desired to study and characterise the function of wheat homologues of s ...
... model or non-model plant species. This is especially usefully in translational research or comparative genomic studies where the gene of interest might have been well characterised in a model species (like Arabidopsis) and it is desired to study and characterise the function of wheat homologues of s ...
Slide 1
... region of the Survivin (BIRC5) gene (Xu et al. 2004). They report that 68% of cancerspecific cell lines (colon, prostate, and breast cancers) contain a C to G transversion at -31 that was not found in any of the normal cell lines tested. BIRC5 is an inhibitor of apoptosis and has been reported as ab ...
... region of the Survivin (BIRC5) gene (Xu et al. 2004). They report that 68% of cancerspecific cell lines (colon, prostate, and breast cancers) contain a C to G transversion at -31 that was not found in any of the normal cell lines tested. BIRC5 is an inhibitor of apoptosis and has been reported as ab ...
Evolution of genetic and genomic features unique to the human
... Accelerated evolution may also occur at the level of whole genes or genomic regions in the form of copy number variations and structural rearrangements. Identification of such regions typically involves looking for HLS sequence copy number expansions and contractions that can range from as small as ...
... Accelerated evolution may also occur at the level of whole genes or genomic regions in the form of copy number variations and structural rearrangements. Identification of such regions typically involves looking for HLS sequence copy number expansions and contractions that can range from as small as ...
Genetic markers, marker assisted selection
... The callipyge locus causes muscular hypertrophy of buttock muscles in sheep with the hypertrophied muscles being less tender than those in normal sheep. This trait has a complex mode of inheritance ( Cockett et al., 1996) and has been mapped to a 400 kb region on chromosome 18 (Berghmans et al., 200 ...
... The callipyge locus causes muscular hypertrophy of buttock muscles in sheep with the hypertrophied muscles being less tender than those in normal sheep. This trait has a complex mode of inheritance ( Cockett et al., 1996) and has been mapped to a 400 kb region on chromosome 18 (Berghmans et al., 200 ...
view
... • Rare alleles may be either young or old and thus may have long- or short range LD • Positive selection causes an unusually rapid rise in allele frequency, occurring over a short enough time that recombination does not substantially break down the haplotype on which the selected mutation occurs Nat ...
... • Rare alleles may be either young or old and thus may have long- or short range LD • Positive selection causes an unusually rapid rise in allele frequency, occurring over a short enough time that recombination does not substantially break down the haplotype on which the selected mutation occurs Nat ...
Page 517 Duplication of the S. cerevisiae genome
... [3] One copy accumulates mutations and becomes a pseudogene (no functional protein product) [4] One copy (or both) diverges functionally. The organism can perform a novel function. Page 517 ...
... [3] One copy accumulates mutations and becomes a pseudogene (no functional protein product) [4] One copy (or both) diverges functionally. The organism can perform a novel function. Page 517 ...
Heterogeneous lengths of copy number mutations
... nucleotide variations and copy number (CN) variations. CN variations represent genomic segments with a size range of ~100 bp to several Mbs demonstrating an altered (or non-neutral) dosage status.5 They are typically introduced in the genome by recombination-based or replication-based mechanisms. Th ...
... nucleotide variations and copy number (CN) variations. CN variations represent genomic segments with a size range of ~100 bp to several Mbs demonstrating an altered (or non-neutral) dosage status.5 They are typically introduced in the genome by recombination-based or replication-based mechanisms. Th ...
A Genetic Analysis of a Co-Expression Network Reveals
... lent support to this theory by identifying overexpression of immune response genes (Kaushik et al., 2005). Recently, several groups have proposed using microarray data to construct gene expression networks and to identify network modules (sets of tightly correlated genes) and highly connected “hub” ...
... lent support to this theory by identifying overexpression of immune response genes (Kaushik et al., 2005). Recently, several groups have proposed using microarray data to construct gene expression networks and to identify network modules (sets of tightly correlated genes) and highly connected “hub” ...
locomotion in a consanguineous kindred the gene
... platforms with Illumina 300 Duo v2 SNP genotype data indicated that the alleles were detected with sensitivity and specificity >99%. Heterozygous SNPs detected at the borders of the homozygous blocks of the affected individuals narrowed the region of homozygosity to 6.74 Mb (Supplemental Table 5). T ...
... platforms with Illumina 300 Duo v2 SNP genotype data indicated that the alleles were detected with sensitivity and specificity >99%. Heterozygous SNPs detected at the borders of the homozygous blocks of the affected individuals narrowed the region of homozygosity to 6.74 Mb (Supplemental Table 5). T ...
Generalized-HMMs - Center for Bioinformatics and
... • Comparative (homology) based gene finders. These align genomic sequences from different species and use the alignments to guide the gene predictions (e.g. TWAIN, SLAM, ...
... • Comparative (homology) based gene finders. These align genomic sequences from different species and use the alignments to guide the gene predictions (e.g. TWAIN, SLAM, ...
00Exem hard
... distance (BD) is the number of breakpoints in g, which is clearly equal to the number of breakpoints in h. The exemplar breakpoint distance (EBD) between G and H is the minimum, over all choices of exemplar strings g and h, of the breakpoint distance between g and h. A reversal transforms a string · ...
... distance (BD) is the number of breakpoints in g, which is clearly equal to the number of breakpoints in h. The exemplar breakpoint distance (EBD) between G and H is the minimum, over all choices of exemplar strings g and h, of the breakpoint distance between g and h. A reversal transforms a string · ...
What Can the Y Chromosome Tell Us about the Origin of Modern
... consequences for its genetics and evolution, some obvious but others less so. SRY must be haploid (present in only one copy per genome) in order for this sex-determining mechanism to work. It therefore has no homologue and so cannot recombine. However, recombination is required for successful meiosi ...
... consequences for its genetics and evolution, some obvious but others less so. SRY must be haploid (present in only one copy per genome) in order for this sex-determining mechanism to work. It therefore has no homologue and so cannot recombine. However, recombination is required for successful meiosi ...
Crossing Over - Biology D118
... cells, four different cells can result. Without crossing over only two different cells could result. 9. Crossing over is tremendously significant in the evolutionary process. For example, a chromosome might acquire an advantageous allele that joins an already advantageous allele. At fertilization, t ...
... cells, four different cells can result. Without crossing over only two different cells could result. 9. Crossing over is tremendously significant in the evolutionary process. For example, a chromosome might acquire an advantageous allele that joins an already advantageous allele. At fertilization, t ...
Human chromosome 21/Down syndrome gene function and
... For example, Amsterdam et al. (2004) recently reported on embryonic lethal knockouts in zebra fish that included 5 chromosome 21 orthologs, among them the functionally unannotated c21orf59 and the “novel nuclear protein 1”, NNP1. From C. elegans and yeast, the interactomes contain data on novel inte ...
... For example, Amsterdam et al. (2004) recently reported on embryonic lethal knockouts in zebra fish that included 5 chromosome 21 orthologs, among them the functionally unannotated c21orf59 and the “novel nuclear protein 1”, NNP1. From C. elegans and yeast, the interactomes contain data on novel inte ...
The Human GCAP1 and GCAP2 Genes Are Arranged in a Tail
... Northern blotting. Retina RNA was separated on 0.43 M formaldehyde agarose gels (Ausubel et al., 1987) and transferred to maximum strength Nytran (Schleicher and Schuell). A multiple tissue RNA blot (Clontech Laboratories, Inc.) was probed with randomprimed (Feinberg and Vogelstein, 1984), linearize ...
... Northern blotting. Retina RNA was separated on 0.43 M formaldehyde agarose gels (Ausubel et al., 1987) and transferred to maximum strength Nytran (Schleicher and Schuell). A multiple tissue RNA blot (Clontech Laboratories, Inc.) was probed with randomprimed (Feinberg and Vogelstein, 1984), linearize ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.