Analysis of Flanking Sequences from Dissociation
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
Analysis of Flanking Sequences from Dissociation
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
Founder Effects, Inbreeding and Hybrid Zones Lecture Outline
... associated with genes that confer a selective advantage). The same change would be predicted for Y chromosomes which are also transmitted down the paternal line, and a similar change for mitochondrial DNA which is passed down the maternal line. ...
... associated with genes that confer a selective advantage). The same change would be predicted for Y chromosomes which are also transmitted down the paternal line, and a similar change for mitochondrial DNA which is passed down the maternal line. ...
A familial inverted duplication/deletion of 2p25.1–25.3
... re-defined by real-time PCR and breakpoint cloning, demonstrating the presence of a 2680 bp single-copy sequence between deleted and duplicated regions and the involvement of a simple repeat with the potential for forming a non-B DNA structure. The rearrangement was not mediated by segmental duplica ...
... re-defined by real-time PCR and breakpoint cloning, demonstrating the presence of a 2680 bp single-copy sequence between deleted and duplicated regions and the involvement of a simple repeat with the potential for forming a non-B DNA structure. The rearrangement was not mediated by segmental duplica ...
Tutorial - 1000 Genomes
... The tool predicts the consequence of this variation, the amino acid position and change (if the variation falls within a protein) and the SNP identifier of known SNPs that occur at this position. The output columns are: ...
... The tool predicts the consequence of this variation, the amino acid position and change (if the variation falls within a protein) and the SNP identifier of known SNPs that occur at this position. The output columns are: ...
RTPrimerDB: the real-time PCR primer and probe database, major
... in which all assays for that particular gene are grouped together. Gene reports A gene report groups all available assays for a particular gene to help the evaluation of their usefulness in a specific experimental context (Figure 1). The overview starts with gene annotation data and links to Entrez ...
... in which all assays for that particular gene are grouped together. Gene reports A gene report groups all available assays for a particular gene to help the evaluation of their usefulness in a specific experimental context (Figure 1). The overview starts with gene annotation data and links to Entrez ...
Commonly Used STR Markers
... • Types of markers: – Simple repeats (with or without microvariants) – Compound repeats – Complex repeats ...
... • Types of markers: – Simple repeats (with or without microvariants) – Compound repeats – Complex repeats ...
click to - White Rose Research Online
... recent study produced low coverage sequence data for 199 B. rapa and 119 B. oleracea accessions to identify SNPs and trace parallel selection signals in the two subgenomes (Cheng et al. 2016). Regions undergoing positive selection could be identified (25 in B. rapa and 58 in B. oleracea), out of whi ...
... recent study produced low coverage sequence data for 199 B. rapa and 119 B. oleracea accessions to identify SNPs and trace parallel selection signals in the two subgenomes (Cheng et al. 2016). Regions undergoing positive selection could be identified (25 in B. rapa and 58 in B. oleracea), out of whi ...
COMPUTATIONAL BIOLOGY
... from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is supposed to list readily relevant and searchable terms, is empty for entry U90223. Unfortun ...
... from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is supposed to list readily relevant and searchable terms, is empty for entry U90223. Unfortun ...
Slides
... Mapping Structural Variation in Humans >1 kb segments - Structural Variations are Common 40% of the genome -Structural Variations are involved in phenotype variation and disease - Until recently most methods for detection were low resolution (>50 kb) ...
... Mapping Structural Variation in Humans >1 kb segments - Structural Variations are Common 40% of the genome -Structural Variations are involved in phenotype variation and disease - Until recently most methods for detection were low resolution (>50 kb) ...
Molecular Detection of Virulence Genes Associated with
... Klebsiella species are gram negative, medium sized rods (0.40.6 x 2-3 μm). They are facultative anaerobic, fermentative, catalase positive, oxidase negative lactose fermenters, reduce nitrate to nitrite and are motile by peritrichous flagella. They are capable of growth on non-enriched media such as ...
... Klebsiella species are gram negative, medium sized rods (0.40.6 x 2-3 μm). They are facultative anaerobic, fermentative, catalase positive, oxidase negative lactose fermenters, reduce nitrate to nitrite and are motile by peritrichous flagella. They are capable of growth on non-enriched media such as ...
Genotyping of Ryanodine receptor 1 (RYR1) gene associated with
... resolution melting (HRM) method has been used as a high-throughput molecular genotyping approach for detection of variation on MAS marker associated with economic traits in pig for many years. Although the HRM is a capable method to identify mutation in the RYR1 gene, it is demonstrated that subopti ...
... resolution melting (HRM) method has been used as a high-throughput molecular genotyping approach for detection of variation on MAS marker associated with economic traits in pig for many years. Although the HRM is a capable method to identify mutation in the RYR1 gene, it is demonstrated that subopti ...
publication
... the shuffling of exons during protein evolution. Allied with this hypothesis was the notion that exons encoded structural and/or functional domains of proteins. Although several notable examples of the latter have been demonstrated, and indeed the presence of introns in such cases could reasonably m ...
... the shuffling of exons during protein evolution. Allied with this hypothesis was the notion that exons encoded structural and/or functional domains of proteins. Although several notable examples of the latter have been demonstrated, and indeed the presence of introns in such cases could reasonably m ...
Mapping strategies for sequence reads (with focus on RNA-seq)
... ... and there would be an excess supply of biostatisticians In the real world... • molecules of interest need to be selected • DNA/RNA needs to be shattered into fragments • fragments need to be amplified • # reads from a fragment is hard to control (0, 1 or more times) • different parts of a class ...
... ... and there would be an excess supply of biostatisticians In the real world... • molecules of interest need to be selected • DNA/RNA needs to be shattered into fragments • fragments need to be amplified • # reads from a fragment is hard to control (0, 1 or more times) • different parts of a class ...
Impact of Tandem Repeats on the Scaling of Nucleotide Sequences
... reciprocal of basepairs (bp) , i.e. (1/bp). Several algorithms have been proposed in the past to determine the scaling exponent of a given sequence [Feder, 1988; Li & Kaneko, 1992; Peng et al., 1992]. Detrended fluctuation analysis DFA and its extensions multifractal DFA (MF-DFA) [Peng et al., 1992; ...
... reciprocal of basepairs (bp) , i.e. (1/bp). Several algorithms have been proposed in the past to determine the scaling exponent of a given sequence [Feder, 1988; Li & Kaneko, 1992; Peng et al., 1992]. Detrended fluctuation analysis DFA and its extensions multifractal DFA (MF-DFA) [Peng et al., 1992; ...
The Big Picture: an outline of the concepts covered to date
... inheritance patterns of genes A. Each diploid individual contains two copies of a given gene B. Each Gene can have different forms called alleles. There are two alleles in a diploid individual The form that is expressed phenotypically in the heterozygote is known as the dominant allele. It is an ope ...
... inheritance patterns of genes A. Each diploid individual contains two copies of a given gene B. Each Gene can have different forms called alleles. There are two alleles in a diploid individual The form that is expressed phenotypically in the heterozygote is known as the dominant allele. It is an ope ...
Biostat Jhsph Edu Hji Courses Genomics Sequencing Ppt
... that span introns. The RNA-Seq graph above the gene model summarizes the quantity of reads, so that each point represents the number of reads covering each nucleotide, per million mapped reads (normalized scale of 0–5.5 reads). (c) Detection and quantification of differential expression. Mouse poly( ...
... that span introns. The RNA-Seq graph above the gene model summarizes the quantity of reads, so that each point represents the number of reads covering each nucleotide, per million mapped reads (normalized scale of 0–5.5 reads). (c) Detection and quantification of differential expression. Mouse poly( ...
Arabidopsis Gene and cDNA Encoding Cell
... thaliana. In Atbfructl and both tomato genes, exon 2 is only 9 bp long and encodes part of a highly conserved region found in a11 known invertase proteins (NDPNG). By way of contrast, in the D. carota gene this short nucleotide sequence is included in exon 1. There is one conflict between the gene s ...
... thaliana. In Atbfructl and both tomato genes, exon 2 is only 9 bp long and encodes part of a highly conserved region found in a11 known invertase proteins (NDPNG). By way of contrast, in the D. carota gene this short nucleotide sequence is included in exon 1. There is one conflict between the gene s ...
Changing Patterns of Gene Regulation in the Evolution of Arthropod
... grammatic representation of some of the gene net- ah, 1989; Fig. 1). works involved in Drosophila A/P, DA7 and P/D axis This description is, of course, an overformation. Details are described in the text, bed: bi- simplified version of embryonic patterning. coicl; Dll: Distal-less; dpp: decapentaple ...
... grammatic representation of some of the gene net- ah, 1989; Fig. 1). works involved in Drosophila A/P, DA7 and P/D axis This description is, of course, an overformation. Details are described in the text, bed: bi- simplified version of embryonic patterning. coicl; Dll: Distal-less; dpp: decapentaple ...
PPT - Blumberg Lab
... • 21 was rich in rRNA genes so made a radiation hybrid panel from patient • Identified hybrid cell carrying the breakpoint – made a genomic library from it • Screened library for clones with both rRNA genes and X chromosome specific sequences – Long, tedious process with many more failures than succ ...
... • 21 was rich in rRNA genes so made a radiation hybrid panel from patient • Identified hybrid cell carrying the breakpoint – made a genomic library from it • Screened library for clones with both rRNA genes and X chromosome specific sequences – Long, tedious process with many more failures than succ ...
comparative genomics, minimal gene
... set of essential functional niches (given specified conditions) rather than of minimal sets of genes. These functional niches differ in their evolutionary/structural redundancy (propensity for NOGD), and two or more distinct solutions have evolved for most of them. This creates enormous combinatoria ...
... set of essential functional niches (given specified conditions) rather than of minimal sets of genes. These functional niches differ in their evolutionary/structural redundancy (propensity for NOGD), and two or more distinct solutions have evolved for most of them. This creates enormous combinatoria ...
Online Repository - Nederlands Tweelingen Register
... Other GWAS datasets with available individual level genetic data can be used in this step, including those of non-European ancestry. Using a GWAS dataset with a larger sample size (>4,000 individuals) did not influence the performance of this step (not shown), and so we used data from the 1000 Geno ...
... Other GWAS datasets with available individual level genetic data can be used in this step, including those of non-European ancestry. Using a GWAS dataset with a larger sample size (>4,000 individuals) did not influence the performance of this step (not shown), and so we used data from the 1000 Geno ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.