Salvia Divinorum
... collections around the world. Virtually all of the Salvia Divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The ...
... collections around the world. Virtually all of the Salvia Divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The ...
Genetic polymorphisms and drug interactions modulating
... CYP2D6 catalyses the O-demethylation of oxycodone to oxymorphone which accounts for 10% of oxycodone metabolites and CYP3A catalyses the N-demethylation of oxycodone to the major (80%) circulating metabolite, noroxycodone (Cone et al., 1983). The additional O-demethylation of noroxycodone to noroxym ...
... CYP2D6 catalyses the O-demethylation of oxycodone to oxymorphone which accounts for 10% of oxycodone metabolites and CYP3A catalyses the N-demethylation of oxycodone to the major (80%) circulating metabolite, noroxycodone (Cone et al., 1983). The additional O-demethylation of noroxycodone to noroxym ...
CHAPTER 2 REVIEW OF LITERATURE SECTION I: COCAINE
... relieve fatigue, and lessen hunger. Chewing the coca leaf was the predominant mode of ingestion of cocaine until 1860, when the drug was isolated by Albert Niemann. The leaves have also been steeped into teas and incorporated into beverages, such as Coca Cola (which no longer contains cocaine.) In t ...
... relieve fatigue, and lessen hunger. Chewing the coca leaf was the predominant mode of ingestion of cocaine until 1860, when the drug was isolated by Albert Niemann. The leaves have also been steeped into teas and incorporated into beverages, such as Coca Cola (which no longer contains cocaine.) In t ...
Handbook of Pharmaceutical Excipients, 7th ed. Sample chapter.
... Mannitol is widely used in pharmaceutical formulations and food products. In pharmaceutical preparations it is primarily used as a diluent (10–90% w/w) in tablet formulations, where it is of particular value since it is not hygroscopic and may thus be used with moisture-sensitive active ingredients. ...
... Mannitol is widely used in pharmaceutical formulations and food products. In pharmaceutical preparations it is primarily used as a diluent (10–90% w/w) in tablet formulations, where it is of particular value since it is not hygroscopic and may thus be used with moisture-sensitive active ingredients. ...
P-Glycoprotein functional activity in peripheral blood lymphocytes. Role of immunosuppressants,
... basolateral membranes, and mediate active transport in absorptive and secretory directions. ...
... basolateral membranes, and mediate active transport in absorptive and secretory directions. ...
Pharmacological and Pharmaceutical Profile of Valsartan: A Review
... the developed and the developing countries. It is also available in combination with other antihypertensive drugs. It is a lipophilic drug and possesses moderate onset of action than other drugs of the same category. The drug is a very good target for the generic industries. It is soluble in the neu ...
... the developed and the developing countries. It is also available in combination with other antihypertensive drugs. It is a lipophilic drug and possesses moderate onset of action than other drugs of the same category. The drug is a very good target for the generic industries. It is soluble in the neu ...
Download CV
... Tsai G, Slusher BS, Sim L, Hedreen JC, Coyle JT. “Reduced excitatory amino acids in amyotrophic lateral sclerosis CNS.” Brain Research, 1991, 556:151-156 Coyle JT, Slusher BS, Tsai G, Rothstein JD, Meyerhoff J, “N-acetyl aspartyl glutamate (NAAG): recent developments.” Excitatory Amino Acid Research ...
... Tsai G, Slusher BS, Sim L, Hedreen JC, Coyle JT. “Reduced excitatory amino acids in amyotrophic lateral sclerosis CNS.” Brain Research, 1991, 556:151-156 Coyle JT, Slusher BS, Tsai G, Rothstein JD, Meyerhoff J, “N-acetyl aspartyl glutamate (NAAG): recent developments.” Excitatory Amino Acid Research ...
as terbinafine base
... No studies on the effects of terbinafine tablets treatment on the ability to drive and use machines have been performed. Patients who experience dizziness as an undesirable effect should avoid driving vehicles or using machines. ADVERSE REACTIONS Adverse Drug reaction Overview Because clinical trial ...
... No studies on the effects of terbinafine tablets treatment on the ability to drive and use machines have been performed. Patients who experience dizziness as an undesirable effect should avoid driving vehicles or using machines. ADVERSE REACTIONS Adverse Drug reaction Overview Because clinical trial ...
Opium Abuse and Its Management
... Myanmar and Laos In Myanmar, cumulatively from 1974 to 2000 in the treatment centres, there were about 36,000 opium users and they comprised 59% of all registered addict and opium was still the preferred drug of abuse followed by heroin (32%) (Central Registry, Department of Health Planning, Ministr ...
... Myanmar and Laos In Myanmar, cumulatively from 1974 to 2000 in the treatment centres, there were about 36,000 opium users and they comprised 59% of all registered addict and opium was still the preferred drug of abuse followed by heroin (32%) (Central Registry, Department of Health Planning, Ministr ...
Urinary Hydrocodone and Metabolite Distributions in
... Statistical significance, with a Bonferroni adjustment due to multiple comparison testing, was set at P 0.005 (23). ...
... Statistical significance, with a Bonferroni adjustment due to multiple comparison testing, was set at P 0.005 (23). ...
Product Monograph Template - Standard - GlaxoSmithKline
... Long-acting beta2-adrenergic agonists (LABA), such as salmeterol, one of the active ingredients in ADVAIR® and ADVAIR® DISKUS®, increase the risk of asthma-related death. Data from a large placebo-controlled US study that compared the safety of salmeterol (SEREVENT® Inhalation Aerosol) or placebo ad ...
... Long-acting beta2-adrenergic agonists (LABA), such as salmeterol, one of the active ingredients in ADVAIR® and ADVAIR® DISKUS®, increase the risk of asthma-related death. Data from a large placebo-controlled US study that compared the safety of salmeterol (SEREVENT® Inhalation Aerosol) or placebo ad ...
TRAMADOL – A Drug to be used cautiously
... of the racemate. As one of the least potent opioid painkillers many people believe tramadol is not addictive. This false sense of security can lead some people to develop an addiction without even realizing it. Tramadol was originally considered to have a much better safety profile than other opioid ...
... of the racemate. As one of the least potent opioid painkillers many people believe tramadol is not addictive. This false sense of security can lead some people to develop an addiction without even realizing it. Tramadol was originally considered to have a much better safety profile than other opioid ...
pdf 53Kb - NSW Bureau of Crime Statistics and Research
... 1984). Most clinical trials are limited as they involve low to moderate doses of anabolic steroids, and cannot be generalised to anabolic steroid users who are taking very high doses (up to 10 times recommended pharmacological dose), often involving several different anabolic steroids (Elashoff et a ...
... 1984). Most clinical trials are limited as they involve low to moderate doses of anabolic steroids, and cannot be generalised to anabolic steroid users who are taking very high doses (up to 10 times recommended pharmacological dose), often involving several different anabolic steroids (Elashoff et a ...
1 EC-NAPROSYN (naproxen delayed
... have been reported to range from 0.12% to 0.19% of total naproxen concentration, compared with 0.05% to 0.075% in younger subjects. The clinical significance of this finding is unclear, although it is possible that the increase in free naproxen concentration could be associated with an increase in t ...
... have been reported to range from 0.12% to 0.19% of total naproxen concentration, compared with 0.05% to 0.075% in younger subjects. The clinical significance of this finding is unclear, although it is possible that the increase in free naproxen concentration could be associated with an increase in t ...
Theo-24®(theophylline anhydrous) Extended
... Caffeine and 3-methylxanthine are the o nly theo phylline metabo lites with pharmaco lo g ic activity. 3methylxanthine has appro ximately o ne tenth the pharmaco lo g ic activity o f theo phylline and serum concentratio ns in adults with no rmal renal functio n are <1 mcg /mL. In patients with end-s ...
... Caffeine and 3-methylxanthine are the o nly theo phylline metabo lites with pharmaco lo g ic activity. 3methylxanthine has appro ximately o ne tenth the pharmaco lo g ic activity o f theo phylline and serum concentratio ns in adults with no rmal renal functio n are <1 mcg /mL. In patients with end-s ...
Pharmacological Significance of Synthetic Heterocycles
... Two hundred years ago, the chemical science was an undivided field; around 1900 a division into inorganic, organic and physical chemistry became necessary. The increase of factual material enforced a progressive segmentation into sub disciplines. A map shows countries and regions neatly separated; s ...
... Two hundred years ago, the chemical science was an undivided field; around 1900 a division into inorganic, organic and physical chemistry became necessary. The increase of factual material enforced a progressive segmentation into sub disciplines. A map shows countries and regions neatly separated; s ...
EC-NAPROSYN (naproxen delayed-release tablets) NAPROSYN (naproxen tablets)
... have been reported to range from 0.12% to 0.19% of total naproxen concentration, compared with 0.05% to 0.075% in younger subjects. The clinical significance of this finding is unclear, although it is possible that the increase in free naproxen concentration could be associated with an increase in t ...
... have been reported to range from 0.12% to 0.19% of total naproxen concentration, compared with 0.05% to 0.075% in younger subjects. The clinical significance of this finding is unclear, although it is possible that the increase in free naproxen concentration could be associated with an increase in t ...
Glucosamine sulfate.fm
... synovial fluid [11]. However, it also exerts specific pharmacological effects on osteoarthritic cartilage and chondrocytes. Glucosamine base must be salified for pharmaceutical use, and glucosamine sulfate is the salt that was originally developed as a prescription drug and used in the vast majority ...
... synovial fluid [11]. However, it also exerts specific pharmacological effects on osteoarthritic cartilage and chondrocytes. Glucosamine base must be salified for pharmaceutical use, and glucosamine sulfate is the salt that was originally developed as a prescription drug and used in the vast majority ...
A Scoping Review of Codeine Use, Misuse and
... study. Extracts may be included in professional journals provided that suitable acknowledgement is made and that the reproduction is not associated with any form of advertising. Application for commercial reproduction should be made to the CODEMISUSED Project, European Commission, 7th Framework, EU. ...
... study. Extracts may be included in professional journals provided that suitable acknowledgement is made and that the reproduction is not associated with any form of advertising. Application for commercial reproduction should be made to the CODEMISUSED Project, European Commission, 7th Framework, EU. ...
Pharmacogenetic Determinants of Codeine Induction by Rifampin
... Inter- and intraphenotypic comparisons were carried out by twoway ANOVA with repeated measurements, followed if appropriate by paired or unpaired Student’s t test or nonparametric test (Wilcoxon signed rank test), as indicated. Linear and Spearman correlation tests were used to evaluate the relation ...
... Inter- and intraphenotypic comparisons were carried out by twoway ANOVA with repeated measurements, followed if appropriate by paired or unpaired Student’s t test or nonparametric test (Wilcoxon signed rank test), as indicated. Linear and Spearman correlation tests were used to evaluate the relation ...
Annex 1 - Emcdda
... The "25I" component within 25I-NBOMe refers to the location of the iodine atom on the phenethylamine nucleus. The "NBOMe" component refers to the N-(2-methoxybenzyl) part of the molecule. There are a number of other "NBOMe" derivatives that have been notified to the Early Warning System. These inclu ...
... The "25I" component within 25I-NBOMe refers to the location of the iodine atom on the phenethylamine nucleus. The "NBOMe" component refers to the N-(2-methoxybenzyl) part of the molecule. There are a number of other "NBOMe" derivatives that have been notified to the Early Warning System. These inclu ...
Cellulose, Chitosan, and Keratin Composite Materials. Controlled
... © 2014 American Chemical Society ...
... © 2014 American Chemical Society ...
Safety and Side Effects of CBD
... of chronic CBD incubation also showed that 25 µM CBD led to morphological changes in the cell lines but not to a directly cytotoxic effect, whereas 1 µM did neither affect cell nor placenta viability. The authors consider this effect cytostatic. Nicardipine was used as the BCRP-substrate in the in v ...
... of chronic CBD incubation also showed that 25 µM CBD led to morphological changes in the cell lines but not to a directly cytotoxic effect, whereas 1 µM did neither affect cell nor placenta viability. The authors consider this effect cytostatic. Nicardipine was used as the BCRP-substrate in the in v ...
Misuse and abuse of quetiapine
... to alcohol, one of them also to cocaine and the second one to marijuana, both were diagnosed with borderline personality disorder and increased the prescribed dose of quetiapine from 200 mg/d to 800 mg/d by themselves. Fisher and Boggs [18] reported a single case of a man addicted to alcohol and wit ...
... to alcohol, one of them also to cocaine and the second one to marijuana, both were diagnosed with borderline personality disorder and increased the prescribed dose of quetiapine from 200 mg/d to 800 mg/d by themselves. Fisher and Boggs [18] reported a single case of a man addicted to alcohol and wit ...
Esam Z. Dajani, Ph.D., FACG
... pharmaceutical patents. The litigation support and testimony services cover the fields of drug injury causation, drug-related medical malpractice, medication errors, drug product liability (e.g., warnings, designs, formulations, labeling), pharmaceutical patent litigations, adverse effects of health ...
... pharmaceutical patents. The litigation support and testimony services cover the fields of drug injury causation, drug-related medical malpractice, medication errors, drug product liability (e.g., warnings, designs, formulations, labeling), pharmaceutical patent litigations, adverse effects of health ...