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LTP
LTP

... and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A's efficiency, as one of the cells firing B, is increased" (Hebb, 1949) • Cells that fire together, wire together ...
11. The front-end visual system - LGN and cortex
11. The front-end visual system - LGN and cortex

... One speculative option is that they may be modeled as processing some (polynomial?) function of the neighboring derivative cells, and thus be involved in complex differential features (see also [Alonso1998a]). As Ohzawa states: "Complex cell receptive fields are not that interesting when measured wi ...
Dorsal Spinocerebellar Tract
Dorsal Spinocerebellar Tract

... Second order neuron is located in the brainstem. Therefore the CROSSING occurs in the brainstem Medial Lemniscus – Cells of origin? - Contralateral brainstem: Gracile Nucleus - Lower Body; Cuneate Nucleus – Upper Body) Medial Lemniscus – projects to (terminates in): - Ipsilateral VPL of thalamus ...
FIGURE LEGENDS FIGURE 25.1 Drawing of the auditory periphery
FIGURE LEGENDS FIGURE 25.1 Drawing of the auditory periphery

... tympani. It stimulates peripheral axons of the spiral ganglion neurons, whose central axons (auditory nerve fibers) send impulses into the brain. In the normal cochlea, frequency is mapped along the cochlear spiral, with the lowest frequencies at the apex of the cochlea (at the top of the figure). T ...
Learning
Learning

... • Learning refers to relatively permanent changes in behavior resulting from practice or experience – Learning can be unlearned – Observation can lead to learning – Learning requires an operational memory system ...
Classical Conditioning Since Pavlov
Classical Conditioning Since Pavlov

... the second group (shocked five times as often as the first) did not, which Pavlov might have found perfectly understandable since, for those animals, both the CS and the context were conditioned. The general acceptance of the contingency idea is discouraging, not only in view of the limitations of t ...
Discovering spatial working memory fields in prefrontal cortex
Discovering spatial working memory fields in prefrontal cortex

... prefrontal cortex including and surrounding the principal sulcus and in the frontal eye field, exhibited mnemonic persistent activity during the delay period. Remarkably, the delay activity of a recorded neuron was selective for preferred spatial cues (the cell’s memory field), and this selectivity ...
Discovering spatial working memory fields in prefrontal cortex
Discovering spatial working memory fields in prefrontal cortex

... prefrontal cortex including and surrounding the principal sulcus and in the frontal eye field, exhibited mnemonic persistent activity during the delay period. Remarkably, the delay activity of a recorded neuron was selective for preferred spatial cues (the cell’s memory field), and this selectivity ...
After Conditioning - Educational Psychology
After Conditioning - Educational Psychology

... an increase in US Negative Contingency: CS predicts a decrease in US Zero Contingency: No learning ...
Neural basis of sensorimotor learning: modifying
Neural basis of sensorimotor learning: modifying

... The simplest learning tasks are related to the classical notion that sensorimotor learning involves the generation of new associations between stimuli (S) and responses (R). Obviously we could learn to stop for a green light instead of a red one. Learning a new arbitrary association changes the cate ...
What`s New in Understanding the Brain
What`s New in Understanding the Brain

... major sensory integration problem.  Not yet understood, this is a Multi-Sensory Neuron problem & can be eliminated by integrating Multi-Sensory Neurons of two Primary Sensory Cortices. This is role of using 2-Senses at the same time – e.g. Paul & Eve’s CDs. ...
Brain Internal Structure (2)
Brain Internal Structure (2)

... aqueduct (of Sylvius). ...
A Biologically Plausible Spiking Neuron Model of Fear Conditioning
A Biologically Plausible Spiking Neuron Model of Fear Conditioning

... Simple fear conditioning experiments demonstrate classical Pavlovian conditioning. These experiments begin with a neutral, usually auditory or visual stimulus and a US such as an electric shock to an animal’s foot. Initially, presentation of the NS has no behavioural effect on the animal, but after ...
Work toward real-time control of a cortical neural prothesis
Work toward real-time control of a cortical neural prothesis

... interest has shifted toward direct communication with the CNS. Research being conducted at Arizona State University, as a part of the NIH’s Neural Prosthesis Program, is attempting to develop a cortical motor prosthesis. The goal is to design a system to record and analyze the activity of neurons in ...
http://www.uvm.edu/~neurogp/pdfs/Pav_Soc_2009.pdf
http://www.uvm.edu/~neurogp/pdfs/Pav_Soc_2009.pdf

... Associative accounts of the etiology of phobias have been criticized because of numerous cases in which clients do not remember a traumatic event with the phobic object. In three lick suppression experiments with rats, we modeled an associative account for such fears. Experiment 1 demonstrated stimu ...
Resection of focal cortical dysplasia located in the upper pre
Resection of focal cortical dysplasia located in the upper pre

... cases had type IIb FCD because of characteristic MR imaging features. Only a part of the lesion was given for histopathological study, and balloon cells were likely missed in the specimen. Functional recovery after cortical resection is determined either by the absence of function in the cortex remo ...
Optogenetic Technology and Its In Vivo Applications 4 BRIEF SCIENTIFIC REVIEWS
Optogenetic Technology and Its In Vivo Applications 4 BRIEF SCIENTIFIC REVIEWS

... illumination and an array of metal electrodes for recording neuronal activity (Zhang et al., 2009). The first in vivo experiments used invertebrate organisms such as the model nematode Caenorhabditis elegans. In order to examine specific behavioral changes triggered by optogenetic tools, researchers ...
Document
Document

... IMPORTANT CONSIDERATIONS: This material logically splits into six basic topic areas, the organization of the brain, the functional relationships among the parts of the brain, the organization of the spinal cord, the functional relationships among the parts of the spinal cord, the functional relation ...
In cognitive neuroscience, the prefrontal cortex represents a kind of
In cognitive neuroscience, the prefrontal cortex represents a kind of

... response properties of neurons in sensory areas is not adequate for investigation in PFC. Indeed, if one is to examine PFC for evidence of information integration, ...
Sensory Areas
Sensory Areas

... • Connect portions of the cerebral cortex and cerebellum • Send axons to cerebellum through the middle cerebellar peduncles The Brain Stem—The Midbrain ...
Neuroanatomy
Neuroanatomy

... Activation of the temporal lobe during recognition of a known face ...
Pain
Pain

... anterior cingulate and prefrontal cortices. • These cortical areas taken together are called the pain matrix. ...
Trigeminal Nerve
Trigeminal Nerve

...  The facial muscles below the forehead receive contralateral cortical innervation (crossed corticobulbar fibers only).  Therefore, a lesion rostral to the facial nucleus—a central facial lesion—results in paralysis of the contralateral facial muscles except the frontalis and orbicularis oculi musc ...
Lecture 1 - Gabriel Kreiman
Lecture 1 - Gabriel Kreiman

... The functional properties of ganglion cells have been extensively examined by electrophysiological recordings that go back to the prominent work of Kuffler (Kuffler, 1953). Retinal neurons (as well as most neurons examined in visual cortex so far) respond most strongly to a circumscribed region of t ...
Nonlinear Behavior of Neocortical Networks
Nonlinear Behavior of Neocortical Networks

... Examination of nonlinear components of network activity may provide a powerful link between the understanding of single neuron behavior and the power of the brain as a whole. Determining how the brain establishes and maintains activity states that allow information processing to occur and the role o ...
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Eyeblink conditioning

Eyeblink conditioning (EBC) is a form of classical conditioning that has been used extensively to study neural structures and mechanisms that underlie learning and memory. The procedure is relatively simple and usually consists of pairing an auditory or visual stimulus (the conditioned stimulus (CS)) with an eyeblink-eliciting unconditioned stimulus (US) (e.g. a mild puff of air to the cornea or a mild shock). Naïve organisms initially produce a reflexive, unconditioned response (UR) (e.g. blink or extension of nictitating membrane) that follows US onset. After many CS-US pairings, an association is formed such that a learned blink, or conditioned response (CR), occurs and precedes US onset. The magnitude of learning is generally gauged by the percentage of all paired CS-US trials that result in a CR. Under optimal conditions, well-trained animals produce a high percentage of CRs (> 90%). The conditions necessary for, and the physiological mechanisms that govern, eyeblink CR learning have been studied across many mammalian species, including mice, rats, guinea pigs, rabbits, ferrets, cats, and humans. Historically, rabbits have been the most popular research subjects.
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