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Composition of the Nervous System
Composition of the Nervous System

... -Ca2+ pumps keep Ca2+ concentration very low inside cell – Ca2+ is important in initiating an action potential when a ligand/ neurotransmitter binds -The transport of the ions is driven by the energy released from the hydrolysis of ATP b) Ion channels/ Ion-selective pores – Passive channels -Require ...
Lesson 4 Section 9.2 Electrochemical Impulse
Lesson 4 Section 9.2 Electrochemical Impulse

... Once the overall charge becomes negative (more + than – on the inside of the membrane) the Na+ gates close The cell works to restore the original polarity by using a sodium/potassium pump o 3 Na+ are pumped out, while 2 K+ are pumped in o ATP fuels this o The membrane is now repolarized, or back to ...
ANPS 019 Beneyto-Santonja 11-30
ANPS 019 Beneyto-Santonja 11-30

... o There is one semicircular canal for each plane of space ...
Chapter 27
Chapter 27

... from inside is greater than Na+ gain  a net loss of K+ from inside  -ve charge inside ...
5.4 Muscle Tissues
5.4 Muscle Tissues

... – 2. Neuroglial Cells: Support and protect neurons • Parts of Neuroglial Cells: – Shwann Cells: produce myelin sheath around the PNS. – Synapse: gap between neurons ...
Name: Date: Period: ______ Unit 7, Part 2 Notes: The Nervous
Name: Date: Period: ______ Unit 7, Part 2 Notes: The Nervous

... Sensory receptor cell  sensory neuron  interneuron in spinal cord  interneurons in brain  interneuron in spinal cord  motor neuron  muscle cell How is a signal transmitted from one end of a neuron to the other? 17. Nerve signals are a result of electrical currents that run down the length of a ...
The synapse.
The synapse.

... chemical synapses • 1) Conduction velocities are far to quick for ordinary metabolic activity (against). • Loew’s study with the two hearts ...
Power Point
Power Point

... During an action potential, depolarization can change the membrane potential from –70 mV to about +30 mV. During repolarization the membrane potential returns to –70 mV. The nerve fiber cannot be stimulated again until repolarization is complete. This period is called the refractory period. If the s ...
Nerves, Hormones and Homeostasis
Nerves, Hormones and Homeostasis

... causes an action potential to develop in the next section of a neuron This develops because of diffusion of the sodium ions between the region with an action potential and the region at the resting potential. When the local current makes the potential rise above the threshold level, voltage gated ch ...
Nerve Impulses ppt
Nerve Impulses ppt

chapter 44 lecture slides
chapter 44 lecture slides

... • Deter the membrane potential from reaching threshold ...
chapter 44 lecture slides
chapter 44 lecture slides

... • Deter the membrane potential from reaching threshold ...
Neurology, Neurons, and EEG
Neurology, Neurons, and EEG

... Neurology is a study of the nervous system. The nervous system is categorized into two physical parts: the peripheral nervous system and the central nervous system. The peripheral nervous system is most easily described by what it is not…it is everything BUT the spinal cord and brain. The central ne ...
Brain and Nervous System
Brain and Nervous System

... membrane. A stimulus first causes sodium channels to open. Because there are many more sodium ions on the outside, and the inside of the neuron is negative relative to the outside, sodium ions rush into the neuron. Remember, sodium has a positive charge, so the neuron becomes more positive and becom ...
Slides - gserianne.com
Slides - gserianne.com

... • How does a neuron “know” its being stimulated? • When stimulated by multiple inputs, how does a neuron “know” whether it should send a nerve impulse (action potential) or not? Answer: Changes in cellular ionic composition But recall that ions are ‘hydrated’ and cannot pass through a cell membrane. ...
Artificial Photosynthesis: A Workshop in Solar Cell Design
Artificial Photosynthesis: A Workshop in Solar Cell Design

... materials powered by a readily available and abundant form of energy in sunlight. Solar cells  mimic the light absorption and electron flow of photosynthesis to produce electricity. The basic  components of a solar cell are a negative electrode (anode) and a positive electrode (cathode)  connected b ...
Nervous System
Nervous System

...  The faster the body can send out signals, the faster one can react. But how does the body increase the speed of conduction?  The axon of some neurons is covered by Schwann cells. Since these cells are made from lipids, they are insulators. This causes the electrical signal to jump over the Schwan ...
1. Cell body - greinerudsd
1. Cell body - greinerudsd

... next neuron thereby passing on the signal. ...
The Neuron
The Neuron

... - Cell membrane open and the positive ions rush in when enough has entered to make the inside more positive than the outside. The cell membrane closes again. This opens/close of cell membrane occurs along the length of the neural membrane creating the neural impulse that travels down the axon = like ...
Lab 11 Nervous System I
Lab 11 Nervous System I

... 4. The binding of a neurotransmitter to a ligand-gated channel results in the outflow of potassium from the cell. What effect does this have on the post-synaptic membrane? ...
Sensory input: Sensory structures, classification by function
Sensory input: Sensory structures, classification by function

... 4. the receptor cell axon (cranial nerve I) projects upward through the olfactory foramina of the cribriform plate and synapses with other neurons in the olfactory bulb ...
Central Nervous System
Central Nervous System

...  After inside flooded with Na+, K+ gates open (they are slower to respond) and let K+ out which are repelled by + inside  Na+ gates remain closed  The inside becomes negative while outside become positive and this repolarizes membrane ...
power point for chap 11
power point for chap 11

... • The potential difference (–70 mV) across the membrane of a resting neuron • It is generated by different concentrations of Na+, K+, Cl, and protein anions (Ax) • Ionic differences are the consequence of: • Differential permeability of the neurilemma to Na+ and K+ • Operation of the sodium-potass ...
Chapter 44
Chapter 44

CLASS #1: 9 Jan 2001
CLASS #1: 9 Jan 2001

... V. BLOOD-BRAIN BARRIER (if time) ...
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Patch clamp



The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells, but is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells. It can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts.The patch clamp technique is a refinement of the voltage clamp. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery made it possible to record the currents of single ion channel molecules for the first time, which improved understanding of the involvement of channels in fundamental cell processes such as action potentials and nerve activity. Neher and Sakmann received the Nobel Prize in Physiology or Medicine in 1991 for this work.
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