Esam Z. Dajani, Ph.D., FACG
... Directed a large, worldwide Phase-III/IV clinical development program for the evaluation of the therapeutic and prophylactic actions of misoprostol against nonsteroidal anti-inflammatory drugs-induced ulcer. Planned and directed the corporate anti-ulcer and anti-diarrheal research programs at Searle ...
... Directed a large, worldwide Phase-III/IV clinical development program for the evaluation of the therapeutic and prophylactic actions of misoprostol against nonsteroidal anti-inflammatory drugs-induced ulcer. Planned and directed the corporate anti-ulcer and anti-diarrheal research programs at Searle ...
DOC - Investor Relations
... This annual report on Form 10-K (“Form 10-K”) includes statements that are, or may be deemed, “forward-looking statements.” In some cases, these forward-looking statements can be identified by the use of forward-looking terminology, including the terms “believes,” “estimates,” “anticipates,” “expect ...
... This annual report on Form 10-K (“Form 10-K”) includes statements that are, or may be deemed, “forward-looking statements.” In some cases, these forward-looking statements can be identified by the use of forward-looking terminology, including the terms “believes,” “estimates,” “anticipates,” “expect ...
Evaluation of the use of static and dynamic models to predict drug
... than Simcyp (84% compared to 58% of the interactions predicted within 2-fold). Differences in the prediction outcomes between the static and dynamic models are attributable to differences in first-pass contribution to DDI. The inclusion of AUCRhfp in static equations leads to systematic overpredicti ...
... than Simcyp (84% compared to 58% of the interactions predicted within 2-fold). Differences in the prediction outcomes between the static and dynamic models are attributable to differences in first-pass contribution to DDI. The inclusion of AUCRhfp in static equations leads to systematic overpredicti ...
United States Anti-Doping Agency - United States Apnea Association
... Over the past 15 to 20 years there has been a resurgence of interest in herbs as supplements and as medications. A common advertising approach is to claim that supplements are “all natural,” with the implication that “all natural” herbs are inherently better than many other more common fruits and ve ...
... Over the past 15 to 20 years there has been a resurgence of interest in herbs as supplements and as medications. A common advertising approach is to claim that supplements are “all natural,” with the implication that “all natural” herbs are inherently better than many other more common fruits and ve ...
... Over the past 15 to 20 years there has been a resurgence of interest in herbs as supplements and as medications. A common advertising approach is to claim that supplements are “all natural,” with the implication that “all natural” herbs are inherently better than many other more common fruits and ve ...
Winter 2013 - Ontario College of Pharmacists
... certain aspects of the regulation and addressed issues that are emerging in practice situations, acknowledging that both physicians and pharmacists have a role to play in optimizing medication management and educating patients on the importance of managing and maintaining continuity of care. Some of ...
... certain aspects of the regulation and addressed issues that are emerging in practice situations, acknowledging that both physicians and pharmacists have a role to play in optimizing medication management and educating patients on the importance of managing and maintaining continuity of care. Some of ...
IDENTIFICATION OF NATURAL PRODUCTS AS ANTIDIABETIC AGENTS Laura Guasch Pàmies
... induction of hypoglycemia. While metformin is the only therapeutic agent that has been demonstrated to reduce macrovascular events in T2DM, its use is not recommended in conditions in which a patient has decreased renal or hepatic function. Metformin is the first-line drug of choice for the treatmen ...
... induction of hypoglycemia. While metformin is the only therapeutic agent that has been demonstrated to reduce macrovascular events in T2DM, its use is not recommended in conditions in which a patient has decreased renal or hepatic function. Metformin is the first-line drug of choice for the treatmen ...
AusPAR Attachment 2: Extract from the Clinical Evaluation Report
... from the Clinical Evaluation Report (CER) prepared by the TGA. This extract does not include sections from the CER regarding product documentation or post market activities. ...
... from the Clinical Evaluation Report (CER) prepared by the TGA. This extract does not include sections from the CER regarding product documentation or post market activities. ...
BoNT_A Presentation UMass Dartmouth 081029
... Efficacy in vitro, & in neuronal cell culture or synaptosomes ...
... Efficacy in vitro, & in neuronal cell culture or synaptosomes ...
Concentrate! Key Takeaways of new insulin products
... devices available, which has implications for both the inpatient and outpatient ...
... devices available, which has implications for both the inpatient and outpatient ...
Charles University in Prague Faculty of Pharmacy in Hradec Králové
... challenging research topics in the pharmaceutical field, mainly due to the presence of the blood-brain barrier (BBB), which separates the blood from the cerebral parenchyma thus limiting the brain uptake of the majority of drugs. Among the several carriers, which have been developed to overcome this ...
... challenging research topics in the pharmaceutical field, mainly due to the presence of the blood-brain barrier (BBB), which separates the blood from the cerebral parenchyma thus limiting the brain uptake of the majority of drugs. Among the several carriers, which have been developed to overcome this ...
Attachment: Product Information: Atazanavir
... approved at the time this AusPAR was published. Cmin ng/mL Geometric Mean (CV%) ...
... approved at the time this AusPAR was published. Cmin ng/mL Geometric Mean (CV%) ...
The Business Benefits of Quality by Design (QbD) Business Benefits of QbD
... regulators would be inspecting the manufacturing site and so the company wanted to achieve a high level of confidence from the regulators regarding the site’s approach and capability. • It is company policy now, but the history is that the approach was driven by a relative small group of like-minde ...
... regulators would be inspecting the manufacturing site and so the company wanted to achieve a high level of confidence from the regulators regarding the site’s approach and capability. • It is company policy now, but the history is that the approach was driven by a relative small group of like-minde ...
Comparison of Inhaled Corticosteroids: An Update
... ence in efficacy. On the other hand, use of a spacer device may alter the systemic availability of an inhaled corticosteroid sufficiently to alter the therapeutic index.22-26 For example, studies using chlorofluorocarbon (CFC)-propelled MDIs of beclomethasone dipropionate and fluticasone propionate ...
... ence in efficacy. On the other hand, use of a spacer device may alter the systemic availability of an inhaled corticosteroid sufficiently to alter the therapeutic index.22-26 For example, studies using chlorofluorocarbon (CFC)-propelled MDIs of beclomethasone dipropionate and fluticasone propionate ...
the PDF
... in clinical trials. In the meantime, hundreds of drugs have been evaluated in clinical trials or in preclinical experiments. To classify the compounds, a concept is proposed assigning drugs to 19 categories according to their mechanism(s) of action, in particular drugs interacting with receptors, en ...
... in clinical trials. In the meantime, hundreds of drugs have been evaluated in clinical trials or in preclinical experiments. To classify the compounds, a concept is proposed assigning drugs to 19 categories according to their mechanism(s) of action, in particular drugs interacting with receptors, en ...
Methamphetamine - Department of Electrical Engineering
... reduction of ephedrine using red phosphorus and iodine. In 1943, Abbott Laboratories requested for its approval from the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, mild depression, postencephalitic parkinsonism, chronic alcoholism, cerebral arteriosclerosis, and hay fev ...
... reduction of ephedrine using red phosphorus and iodine. In 1943, Abbott Laboratories requested for its approval from the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, mild depression, postencephalitic parkinsonism, chronic alcoholism, cerebral arteriosclerosis, and hay fev ...
Clinical Manual Part 2 Drug Infusion Guidelines
... guidelines are standardised to assist staff from widely differing clinical backgrounds. Use of standard guidelines assists in preventing drug administration errors and aids in the handover of patients. They do not preclude the infusion of other drugs of use of other concentrations, if these are requ ...
... guidelines are standardised to assist staff from widely differing clinical backgrounds. Use of standard guidelines assists in preventing drug administration errors and aids in the handover of patients. They do not preclude the infusion of other drugs of use of other concentrations, if these are requ ...
Original salbutamol versus similar salbutamol in
... National Health Emergency10 and the prescription of generics or international common denomination (ICD) drugs was implemented.11 As a result, there has been an increase of trademarks for the drug salbutamol, with 25 brand names being marketed in the country today.12 The hypothesis of this paper aris ...
... National Health Emergency10 and the prescription of generics or international common denomination (ICD) drugs was implemented.11 As a result, there has been an increase of trademarks for the drug salbutamol, with 25 brand names being marketed in the country today.12 The hypothesis of this paper aris ...
disodium phosphate - PAN Pesticide Database
... PHOSPHATE WHICH IS VERY ALKALINE & HAS CAUSTIC ACTION. [Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980. 745]**PEER REVIEWED** Oral administration is safer, but careful monitoring of serum electrolyte levels and renal function is necessar ...
... PHOSPHATE WHICH IS VERY ALKALINE & HAS CAUSTIC ACTION. [Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980. 745]**PEER REVIEWED** Oral administration is safer, but careful monitoring of serum electrolyte levels and renal function is necessar ...
The New High 2013
... of LSD. 25I is very potent and is active at extremely low (μg microgram level) doses, most frequently observed as blotter paper doses. Because this chemical is new to the “legal high” market, it has not been widely seen, however, it has already been encountered in several States with reports of abus ...
... of LSD. 25I is very potent and is active at extremely low (μg microgram level) doses, most frequently observed as blotter paper doses. Because this chemical is new to the “legal high” market, it has not been widely seen, however, it has already been encountered in several States with reports of abus ...
Decreased Serum Concentrations of Tamoxifen
... converts androgens to estrogens in peripheral fat tissue (3). This conversion is the main estrogen source in postmenopausal women. In addition, aminoglutethimide may reduce the con centration of plasma estrogens by enhancement of estrogen metabolism (10, 11). Aminoglutethimide causes response rates ...
... converts androgens to estrogens in peripheral fat tissue (3). This conversion is the main estrogen source in postmenopausal women. In addition, aminoglutethimide may reduce the con centration of plasma estrogens by enhancement of estrogen metabolism (10, 11). Aminoglutethimide causes response rates ...
Chapter 8 - Denali Rx
... USP Chapter 795 • Technician should always have pharmacist check beyond-use dating. • Beyond-use dating for sterile preparations is stricter: – It may be as little as 24 to 72 hours. ...
... USP Chapter 795 • Technician should always have pharmacist check beyond-use dating. • Beyond-use dating for sterile preparations is stricter: – It may be as little as 24 to 72 hours. ...
Amphotericin B as a mycolic acid specific targeting agent in tuberculosis
... I would humbly like to thank the following individuals and organizations for their support towards my completion of my MSc. degree. Most importantly, our Creator and King, for the guidance and support in the good and trying times and never leaving my side. Prof. J.A. Verschoor my promoter, for his d ...
... I would humbly like to thank the following individuals and organizations for their support towards my completion of my MSc. degree. Most importantly, our Creator and King, for the guidance and support in the good and trying times and never leaving my side. Prof. J.A. Verschoor my promoter, for his d ...
Study of the interaction between 3,4- methylenedioximethamphetamine and the endocannabinoid system
... Tolerance may develop to some of the effects of a drug but not to others. The reverse situation occurs when repeated administration of the same drug dose elicits escalating effects. This process is known as sensitization. Repeated drug administration induces the development of an adaptive state know ...
... Tolerance may develop to some of the effects of a drug but not to others. The reverse situation occurs when repeated administration of the same drug dose elicits escalating effects. This process is known as sensitization. Repeated drug administration induces the development of an adaptive state know ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.