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PRODUCT MONOGRAPH PrZOLOFT® (sertraline hydrochloride) 25
PRODUCT MONOGRAPH PrZOLOFT® (sertraline hydrochloride) 25

... During clinical testing in depressed patients, hypomania or mania occurred in approximately 0.6% of ZOLOFT (sertraline hydrochloride) treated patients. Activation of mania/hypomania has also been reported in a small proportion of patients with Major Affective Disorder treated with other marketed ant ...
Effects of Phentermine on Responding Maintained under Multiple
Effects of Phentermine on Responding Maintained under Multiple

... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
Effects of Phentermine on Responding Maintained under Multiple
Effects of Phentermine on Responding Maintained under Multiple

... treatments can be developed that will decrease cocaine abuse in humans. One approach to assessing this possibility is to test potential treatments on behaviors associated with the abuse potential of cocaine (Woolverton and Kleven, 1991). A number of reports have shown that cocaine self-administratio ...
5-country RAR report
5-country RAR report

... a. What  are  the  recent  trends  and  developments  in  NPS  use  among  PUDH?   b. What  patterns  of  use  can  be  distinguished?   c. Which  factors  influence  the  choice  for  NPS?   i. What  do  PUDH  report  on  the  positive ...
CONTROLLED SUBSTANCES
CONTROLLED SUBSTANCES

... (d) "Electronic signature" means an electronic sound, symbol, or process attached to or logically associated with a record and executed or adopted by a person with the intent to sign the record. An electronic signature also is a unique identifier protected by appropriate security measures such that ...
Development and validation of gas chromatography method for low
Development and validation of gas chromatography method for low

... Hydrochloride. The molecular formula is C21H21ClN4OS.HCl and the molecular weight is 449.42. Methyl chloride, Ethyl chloride and Isopropyl chloride may form at the salt formation step, as Ziprasidone base in alcohol solvent (Methanol, Ethanol or Isopropanol) is treated with hydrochloric acid leading ...
Hydrocortisone, Hydrocortisone Acetate, Hydrocortisone
Hydrocortisone, Hydrocortisone Acetate, Hydrocortisone

... corticosteroid preparation or oral administration of a corticosteroid should be considered. Dosage for infants and children should be based on the severity of the disease and the response of the patient rather than on strict adherence to dosage indicated by age, body weight, or body surface area. Af ...
Handbook of Pharmaceutical Excipients, 7th ed. Sample chapter.
Handbook of Pharmaceutical Excipients, 7th ed. Sample chapter.

... and plants; it is present in small quantities in almost all vegetables. Laxative effects may occur if mannitol is consumed orally in large quantities.(27) If it is used in foods as a bodying agent and daily ingestion of over 20 g is foreseeable, the product label should bear the statement ‘excessive ...
LC-Tandem MS Detection of Covalent Binding of Acetaminophen to
LC-Tandem MS Detection of Covalent Binding of Acetaminophen to

... 120.07 (immonium ion of phenylalanine). To further characterise the NAPQI-CPF product, and to enable quantification of NAPQI-CPF in patient samples, a large scale synthesis was performed. Acetaminophen (32 mg) was oxidised to NAPQI in 75 mL chloroform, as described above, and stirred vigorously for ...
Chestal ® Cough Monograph - Boiron USA for Health Care
Chestal ® Cough Monograph - Boiron USA for Health Care

... The formula for Chestal and Children’s Chestal combines several homeopathic medicines. These medicines are manufactured according to the Homeopathic Pharmacopoeia of the United States’ guidelines, using the highest standards of production and quality control. Indications for homeopathic medicines ha ...
The Making of a CYP3A Biomarker Panel for Guiding
The Making of a CYP3A Biomarker Panel for Guiding

... Inter-individual variability in drug absorption, distribution, metabolism and elimination (ADME), arising from both genetic and non-genetic factors, is a main cause of therapeutic failure or undesirable adverse effects. To optimize drug response, multiple strategies have been developed to tailor ind ...
Arkansas Medicaid Pharmacy Prior Authorization Criteria
Arkansas Medicaid Pharmacy Prior Authorization Criteria

... Prescribers may request an override for nonpreferred drugs by calling the UAMS College of Pharmacy Evidence-Based Prescription Drug Program Help Desk at 1-866-250-2518 (toll-free) or 501-526-4200 (local.) The Arkansas Medicaid Preferred Drug List may be found at this link. https://arkansas.magellanr ...
Polysaccharide peptides from COV-1 strain of Coriolus versicolor
Polysaccharide peptides from COV-1 strain of Coriolus versicolor

... In another study, PSP restored cyclophosphamide-induced immuno-suppression by increasing the functions of natural killer cells in patients (Qian et al., 1999), although the mechanisms remain uncertain. In Hong Kong, PSP is commonly used as a health product to enhance the ‘‘immunomodulatory functions ...
2015 Guidelines of the Taiwan Society of Cardiology and the
2015 Guidelines of the Taiwan Society of Cardiology and the

... have been loosened in high risk patients. The Executive Board members of TSOC and the Taiwan Hypertension Society (THS) aimed to review updated information about the management of hypertension to publish an updated hypertension guideline in Taiwan. We recognized that hypertension is the most importa ...
OXYCODONE HCI/NIACIN - Acura Pharmaceuticals
OXYCODONE HCI/NIACIN - Acura Pharmaceuticals

... Pharmaceuticals, Inc., and King Pharmaceuticals, Inc. © 2009 King Pharmaceuticals, Inc. All rights reserved. Presented at the American Society of Addiction Medicine’s 40th Annual Medical-Scientific Conference, New Orleans, LA, April 30–May 3, 2009. ...
Vol 1   Pg 2 EXECUTIVE SUMMARY
Vol 1 Pg 2 EXECUTIVE SUMMARY

... FDA states in it’s proposed rule, “at their (ie, OTC acetaminophen-containing products) recommended doses, these products are only rarely associated with serious adverse events relative to the number of consumers who use these products.” [71 FR 77314 at 77315]. Elsewhere in FDA’s proposed rule, FDA ...
1. Exposure Data - IARC Monographs
1. Exposure Data - IARC Monographs

... treated with anti-thyroid drugs only was 1.3 (95% confidence interval [CI], 1.1–1.6) for deaths from all cancers, which was chiefly due to significantly more deaths from oral cancer (4.2; 95% CI, 1.3–9.7; five cases) and brain tumours (3.7; 95% CI, 1.2–8.6; five cases). The excess risk for death fro ...
Thalidomide: The Tragedy of Birth Defects and the Effective
Thalidomide: The Tragedy of Birth Defects and the Effective

... severe birth defects in thousands of children. Though the use of thalidomide was banned in most countries at that time, thalidomide proved to be a useful treatment for leprosy and later, multiple myeloma. In rural areas of the world that lack extensive medical surveillance initiatives, thalidomide t ...
(By authority conferred on the board of pharmacy by sections... and 7217 of 1978 PA 368, MCL 333.7201, 333.7204, 333.7211,... DEPARTMENT OF LICENSING AND REGULATORY AFFAIRS
(By authority conferred on the board of pharmacy by sections... and 7217 of 1978 PA 368, MCL 333.7201, 333.7204, 333.7211,... DEPARTMENT OF LICENSING AND REGULATORY AFFAIRS

... (d) "Electronic signature" means an electronic sound, symbol, or process attached to or logically associated with a record and executed or adopted by a person with the intent to sign the record. An electronic signature also is a unique identifier protected by appropriate security measures such that ...
The effect of anticholinergic drugs on the
The effect of anticholinergic drugs on the

... secretion is also of importance because of their frequent use in the treatment of peptic ulceration; it would be disadvantageous if they reduced the secretion of mucus because mucus is considered a protection against peptic ulceration by its physical and chemical properties (Bradley, 1933; Hollander ...
biodegradable implants with different drug release - diss.fu
biodegradable implants with different drug release - diss.fu

... thermoplastic aliphatic poly(esters) (Jain 2000). These polymers are commercially available in different molecular weights, co-polymer ratios and chemical end groups. Interest in the use of these polymers for pharmaceutical applications and medical devices has increased extensively due to their biod ...
Frequency, Type and Causes of Medication Errors in Pediatric
Frequency, Type and Causes of Medication Errors in Pediatric

... important issue for our healthcare system and health care providers(1) and in this regard medication errors are used as the index to assess patient safety in hospitals. Medication errors are one of the most common medical errors(2) and its incidence rate have been reported 5.6 cases per 1000 patient ...
Nicotine increases sucrose selfadministration and seeking in rats
Nicotine increases sucrose selfadministration and seeking in rats

... Associations between nicotine in cigarettes and food consumption may alter the incentive value of food such that food cue-reactivity is exaggerated during abstinence from smoking. This effect may contribute to the weight gain associated with cessation of smoking. We examined the effects of nicotine ...
KEY and EXPLANATION for SET-A
KEY and EXPLANATION for SET-A

... Answer: B Explanation: The large intestine is heavily colonized by certain types of bacteria, which synthesize vitamin K and folic acid. They include Escherichia coli, Enterobacter aerogenes, Streptococcus faecalis and Clostridium perfringens. These microbes are commensals, i.e. normally harmless, i ...
ERLN-TB expert opinion on the use of the rapid molecular assays
ERLN-TB expert opinion on the use of the rapid molecular assays

... Genotype MTBDRsl (Hain Lifescience, GmbH, Germany), are based on the targeted amplification (polymerase chain reaction [PCR]) of specific fragments in the M. tuberculosis genome followed by hybridization of PCR products to oligonucleotide probes immobilised on membranes. These assays are capable of ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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