Pharmacological and Pharmaceutical Profile of Valsartan: A Review
... Angiotensin II Receptor type 1 antagonists have been widely used in treatment of diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Their beneficial effects are related to inhibition of Angiotensin II by blockade of AT1 receptor. Valsartan is an orally active ...
... Angiotensin II Receptor type 1 antagonists have been widely used in treatment of diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Their beneficial effects are related to inhibition of Angiotensin II by blockade of AT1 receptor. Valsartan is an orally active ...
IPD Treatment Report
... after a single morning dose in diabetic patients. Glyburide is unique among sulfonylureas in that it not only binds to the pancreatic B cell membrane sulfonylurea receptor but also becomes sequestered within the B cell. This may also contribute to its prolonged biologic effect despite its relatively ...
... after a single morning dose in diabetic patients. Glyburide is unique among sulfonylureas in that it not only binds to the pancreatic B cell membrane sulfonylurea receptor but also becomes sequestered within the B cell. This may also contribute to its prolonged biologic effect despite its relatively ...
DIABETES MELLITUS
... after a single morning dose in diabetic patients. Glyburide is unique among sulfonylureas in that it not only binds to the pancreatic B cell membrane sulfonylurea receptor but also becomes sequestered within the B cell. This may also contribute to its prolonged biologic effect despite its relatively ...
... after a single morning dose in diabetic patients. Glyburide is unique among sulfonylureas in that it not only binds to the pancreatic B cell membrane sulfonylurea receptor but also becomes sequestered within the B cell. This may also contribute to its prolonged biologic effect despite its relatively ...
Annex 1 - Emcdda
... often printed with distinctive designs and perforated so they can be torn into small, singledose units. There are also reports of seizures in powder, including capsules containing powder, and in liquid form. It is used predominantly by sublingual and buccal administration (blotters), there are also ...
... often printed with distinctive designs and perforated so they can be torn into small, singledose units. There are also reports of seizures in powder, including capsules containing powder, and in liquid form. It is used predominantly by sublingual and buccal administration (blotters), there are also ...
NLA Task Force On Statin Safety - 2014 Update
... a period of extended use (ie, a longer period than what is typically captured in clinical trials designed to examine efficacy), (3) occur in subsets of the population that are especially susceptible, and (4) that have multiple causes (other than statins) in the general population. Additionally, the ...
... a period of extended use (ie, a longer period than what is typically captured in clinical trials designed to examine efficacy), (3) occur in subsets of the population that are especially susceptible, and (4) that have multiple causes (other than statins) in the general population. Additionally, the ...
Pharmacogenetic Determinants of Codeine Induction by Rifampin
... were requested not to use any medications, including alcohol and over-the-counter medications, for the week before the initiation of the study and throughout the entire study period. Mean (6 S.E.M.) weight of the EM subjects was 78.7 6 2.1 kg, and their mean age was 32.1 6 1.1 years. Mean weight (87 ...
... were requested not to use any medications, including alcohol and over-the-counter medications, for the week before the initiation of the study and throughout the entire study period. Mean (6 S.E.M.) weight of the EM subjects was 78.7 6 2.1 kg, and their mean age was 32.1 6 1.1 years. Mean weight (87 ...
EMMANUEL ORMAN - Kwame Nkrumah University of Science
... likely to be coding for Artemisinin resistance, it has become pertinent to extend the search for new agents. This study was undertaken to evaluate the In-vivo antiplasmodial effects of traditionally used medicinal plants for malaria treatment. It also sought to evaluate them for possible future comp ...
... likely to be coding for Artemisinin resistance, it has become pertinent to extend the search for new agents. This study was undertaken to evaluate the In-vivo antiplasmodial effects of traditionally used medicinal plants for malaria treatment. It also sought to evaluate them for possible future comp ...
product monograph
... and problems with fluid changes. Epinephrine should be administered with caution since it may not have its usual effects in the treatment of anaphylaxis. On the one hand, larger doses of epinephrine may be needed to overcome the bronchospasm, while on the other, these doses can be associated with ex ...
... and problems with fluid changes. Epinephrine should be administered with caution since it may not have its usual effects in the treatment of anaphylaxis. On the one hand, larger doses of epinephrine may be needed to overcome the bronchospasm, while on the other, these doses can be associated with ex ...
Paediatric formulations of L-arginine for the use in urea cycle disorders
... has been internationally recognised [146]. Often unlicensed and off-label medicines are the only ones available yet which have not been clinically tested for safety, efficacy and quality in this age group. Most medicines administered to adults have a product licence that outlines the particular indi ...
... has been internationally recognised [146]. Often unlicensed and off-label medicines are the only ones available yet which have not been clinically tested for safety, efficacy and quality in this age group. Most medicines administered to adults have a product licence that outlines the particular indi ...
Martindale: The Complete Drug Reference
... Parenteral doses of cefuroxime may need to be reduced in renal impairment. Licensed product information suggests the following doses based on creatinine clearance (CC): CC 10 to 20 mL/minute: 750 mg twice daily ...
... Parenteral doses of cefuroxime may need to be reduced in renal impairment. Licensed product information suggests the following doses based on creatinine clearance (CC): CC 10 to 20 mL/minute: 750 mg twice daily ...
Download CV
... Tsai G, Forloni G, Robinson MB, *Stauch B, Coyle JT. “Calcium-dependent evoked release of N[3H]Acetylaspartate from the optic pathway.” J Neurochem, 1988, 51:1956-1959 *Stauch B, Robinson MB, Forloni G, Tsai G, Coyle JT. “The effects of N-acetylated alpha-linked acidic dipeptidase (NAALADase) inhibi ...
... Tsai G, Forloni G, Robinson MB, *Stauch B, Coyle JT. “Calcium-dependent evoked release of N[3H]Acetylaspartate from the optic pathway.” J Neurochem, 1988, 51:1956-1959 *Stauch B, Robinson MB, Forloni G, Tsai G, Coyle JT. “The effects of N-acetylated alpha-linked acidic dipeptidase (NAALADase) inhibi ...
Intranasal (IN) Medication Administration MBED Clinical Practice
... INDICATIONS: Dexmedetomidine is indicated for short-term (< 24 hrs) sedation of intubated and mechanically ventilated patients in the intensive care setting. *Currently looking into its off-label use for procedural sedation in pediatrics when used intranasally. CLINICAL PHARMACOLOGY: Dexmedetomidine ...
... INDICATIONS: Dexmedetomidine is indicated for short-term (< 24 hrs) sedation of intubated and mechanically ventilated patients in the intensive care setting. *Currently looking into its off-label use for procedural sedation in pediatrics when used intranasally. CLINICAL PHARMACOLOGY: Dexmedetomidine ...
Hydrocortisone, Hydrocortisone Acetate
... treatment of ulcerative colitis, 100 mg of hydrocortisone is administered nightly as a retention enema. The patient should lie on his left side during and for 30 minutes after administration of the retention enema so that the drug will distribute throughout the left colon; the enema should be retain ...
... treatment of ulcerative colitis, 100 mg of hydrocortisone is administered nightly as a retention enema. The patient should lie on his left side during and for 30 minutes after administration of the retention enema so that the drug will distribute throughout the left colon; the enema should be retain ...
Pharmacological Significance of Synthetic Heterocycles
... specifically appropriate to emphasize the role of heterocycles, since analogies to the roles of other classes of organic compounds are easily found. In fact, dyes, luminophores, herbicides, pesticides and drugs do not necessarily have to be heterocyclic in structure. In a similar fashion there are m ...
... specifically appropriate to emphasize the role of heterocycles, since analogies to the roles of other classes of organic compounds are easily found. In fact, dyes, luminophores, herbicides, pesticides and drugs do not necessarily have to be heterocyclic in structure. In a similar fashion there are m ...
supernus pharmaceuticals, inc.
... approved, the product could be the first and only product available to treat this condition, which is prevalent in ADHD, autism, schizophrenia, and bipolar patients. With no FDA-approved therapies to treat impulsive aggression, this represents a significant unmet medical need. We are pleased and ver ...
... approved, the product could be the first and only product available to treat this condition, which is prevalent in ADHD, autism, schizophrenia, and bipolar patients. With no FDA-approved therapies to treat impulsive aggression, this represents a significant unmet medical need. We are pleased and ver ...
FETAL MORPHINE METABOLISM AND CLEARANCE ARE
... The infusions contained 0.5 U/ml heparin. They were filtered through 0.22m, 25-mm MCE filters (Fisher Scientific, Pittsburgh, PA) into sterile Viaflex infusion bags (Baxter-Clinitech Division, Dearfield, IL). The infusion bags were wrapped in aluminum foil and stored at ⫺20°C until they were ready ...
... The infusions contained 0.5 U/ml heparin. They were filtered through 0.22m, 25-mm MCE filters (Fisher Scientific, Pittsburgh, PA) into sterile Viaflex infusion bags (Baxter-Clinitech Division, Dearfield, IL). The infusion bags were wrapped in aluminum foil and stored at ⫺20°C until they were ready ...
AMERICAN ACADEMY OF PEDIATRICS Adolescents and Anabolic
... The use of a variety of substances has long accompanied efforts to enhance athletic performance.1 Such use is not limited to professional and Olympic athletes. Studies focusing on anabolic steroids have shown a continuing and significant increase of use among adolescent athletes and nonathletes alik ...
... The use of a variety of substances has long accompanied efforts to enhance athletic performance.1 Such use is not limited to professional and Olympic athletes. Studies focusing on anabolic steroids have shown a continuing and significant increase of use among adolescent athletes and nonathletes alik ...
Full-Text PDF
... evaluation of the interactions between nanocarriers and biological systems is of key importance to evaluation of the interactions between nanocarriers and biological systems is of key importance to assess the reliability of the delivery systems. The successful translation of nano-formulations to the ...
... evaluation of the interactions between nanocarriers and biological systems is of key importance to evaluation of the interactions between nanocarriers and biological systems is of key importance to assess the reliability of the delivery systems. The successful translation of nano-formulations to the ...
Buprenorphine and Naloxone: Clinical Pharmacology Abuse Liability
... – Ceiling effects so safer in overdose – Less/absent effects in µ-dependent addicts Kappa antagonist – Less euphoria ...
... – Ceiling effects so safer in overdose – Less/absent effects in µ-dependent addicts Kappa antagonist – Less euphoria ...
Recommendations for Management of Clinically Significant Drug
... Statins reduce morbidity and mortality in patients with known atherosclerotic cardiovascular disease (ASCVD) and in many primary prevention patients.4–9 Current guidelines recommend high-intensity statin therapy in all patients with ASCVD age ≤75 years and moderate- to high-intensity statin therapy ...
... Statins reduce morbidity and mortality in patients with known atherosclerotic cardiovascular disease (ASCVD) and in many primary prevention patients.4–9 Current guidelines recommend high-intensity statin therapy in all patients with ASCVD age ≤75 years and moderate- to high-intensity statin therapy ...
Erythromycin delayed release capsules USP
... Neonates The safety of ERYC for use in neonates has not been established. Geriatrics: Clinical studies with ERYC did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. In general, dose selection for an elderly patient shou ...
... Neonates The safety of ERYC for use in neonates has not been established. Geriatrics: Clinical studies with ERYC did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. In general, dose selection for an elderly patient shou ...
Piracetam - Rebound Health
... as Raynaud's phenomenon[42] and deep-vein thrombosis.[17][43] It is an extremely safe antithrombotic agent that operates through the novel mechanism of inhibiting platelet aggregation and enhancing blood-cell deformability.[17]Because traditional anti-thrombotic drugs operate through the separate me ...
... as Raynaud's phenomenon[42] and deep-vein thrombosis.[17][43] It is an extremely safe antithrombotic agent that operates through the novel mechanism of inhibiting platelet aggregation and enhancing blood-cell deformability.[17]Because traditional anti-thrombotic drugs operate through the separate me ...
overview of comments received on community - EMA
... resources, disregard the intentions of the UNESCO in a very brute manner. Scientific studies established in the last years mainly concentrated on depression for the time giving as mentioned in this monograph. This might be fundamental for wellestablished use and full applications but not for traditi ...
... resources, disregard the intentions of the UNESCO in a very brute manner. Scientific studies established in the last years mainly concentrated on depression for the time giving as mentioned in this monograph. This might be fundamental for wellestablished use and full applications but not for traditi ...
CURRICULUM VITAE
... interactions for the treatment of neuropathic pain, chemotherapy-induced neuropathy, TBI and post-traumatic stress disorder. We have recently reported (publication in neuropharmacology, in press as of 06/10/2015) that such novel inhibitors are very effective in treating pain and chemotherapy induced ...
... interactions for the treatment of neuropathic pain, chemotherapy-induced neuropathy, TBI and post-traumatic stress disorder. We have recently reported (publication in neuropharmacology, in press as of 06/10/2015) that such novel inhibitors are very effective in treating pain and chemotherapy induced ...
CARISOPRODOL Tablets, USP Rx Only
... Treatment of Overdosage: Basic life support measures should be instituted as dictated by the clinical presentation of the carisoprodol overdose. Vomiting should not be induced because of the risk of CNS and respiratory depression, and subsequent aspiration. Circulatory support should be administered ...
... Treatment of Overdosage: Basic life support measures should be instituted as dictated by the clinical presentation of the carisoprodol overdose. Vomiting should not be induced because of the risk of CNS and respiratory depression, and subsequent aspiration. Circulatory support should be administered ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.