Codeine and paracetamol use in children
... 1. Opioids may be required for second line analgesia in cases where the combination of paracetamol and a NSAID are inadequate. This can represent a problem in that dosing after discharge may not be f ...
... 1. Opioids may be required for second line analgesia in cases where the combination of paracetamol and a NSAID are inadequate. This can represent a problem in that dosing after discharge may not be f ...
Public Assessment Report Scientific discussion AlendroSteo Kit 70
... Quality control of drug product The product specifications and analytical procedures for the individual drug products were assessed and authorized as part of the registration procedure for the respective drug products. No additional specifications are proposed or needed for the generic combination p ...
... Quality control of drug product The product specifications and analytical procedures for the individual drug products were assessed and authorized as part of the registration procedure for the respective drug products. No additional specifications are proposed or needed for the generic combination p ...
Amiodarone - pharminfotech
... is unclear whether cumulative effects, active metabolites or both are responsible for the differences. Can the brands of oral amiodarone be switched safely? Amiodarone is not on the interchangeable medicine list, so it is preferable that a patient remains on the same brand if possible. There have be ...
... is unclear whether cumulative effects, active metabolites or both are responsible for the differences. Can the brands of oral amiodarone be switched safely? Amiodarone is not on the interchangeable medicine list, so it is preferable that a patient remains on the same brand if possible. There have be ...
Opioid analgesics
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
... in prehistorical times (e.g. in Egypt, Ebers’Papyrus – XVI BC) as an analgesic, tranquillizer, antitussive drug, and for treating diarrhoea. The principal active ingredient in crude opium – morphine, was isolated in 1806 from Frederic Sertűrner, who tested pure drug on himself and three young men. H ...
ACSM outline - Geriatric Assessment Tool Kit
... Weaker diuretic than the other 2 types, but does not deplete Potassium ↓ Afterload (arterial), ↓ Preload (venous) For: Dysrhythmia (not used as much as in the past) Sodium channel blockers: decreases cardiac membrane excitability For: Dysrhythmia Prolongs cardiac re-polarization, preventing too-rapi ...
... Weaker diuretic than the other 2 types, but does not deplete Potassium ↓ Afterload (arterial), ↓ Preload (venous) For: Dysrhythmia (not used as much as in the past) Sodium channel blockers: decreases cardiac membrane excitability For: Dysrhythmia Prolongs cardiac re-polarization, preventing too-rapi ...
Breathe in, Breathe out, How to Pick `em Out: Selecting Inhalers for
... albuterol vs PRN albuterol – No difference in level of asthma control – No difference in efficacy or side effects ...
... albuterol vs PRN albuterol – No difference in level of asthma control – No difference in efficacy or side effects ...
pharmacogenetics of pain
... Methadone dosing in heroin substitution may be decreased in carriers ABCB1 variant.[32] Loperamide an opioid used for its antidiarrheal properties does not produce high CNS concentrations because of its poor absorption and rapid elimination. However, in the ABCB1 343577 variant it produced significa ...
... Methadone dosing in heroin substitution may be decreased in carriers ABCB1 variant.[32] Loperamide an opioid used for its antidiarrheal properties does not produce high CNS concentrations because of its poor absorption and rapid elimination. However, in the ABCB1 343577 variant it produced significa ...
Evaluation of H1-Antihistamine usage among dermatology
... generic names usually provides flexibility to the dispensing pharmacist and generic drugs are less expensive than brand-name drugs. [12] First-generation H1-antihistamines, all of which are sedating can reduce rapid eye movement (REM)-sleep, impair learning and reduce work efficiency. They are impli ...
... generic names usually provides flexibility to the dispensing pharmacist and generic drugs are less expensive than brand-name drugs. [12] First-generation H1-antihistamines, all of which are sedating can reduce rapid eye movement (REM)-sleep, impair learning and reduce work efficiency. They are impli ...
formulation and evaluation of effervescent granules of an anti
... drugs help to alleviate the symptoms of allergy, and are imperative in the recovery of acute anaphylaxis, but play little role in chronic treatment of allergic disorders2. Drugs that are difficult to digest or disruptive to the stomach, pH sensitive drugs, drugs requiring a large dose can be formu ...
... drugs help to alleviate the symptoms of allergy, and are imperative in the recovery of acute anaphylaxis, but play little role in chronic treatment of allergic disorders2. Drugs that are difficult to digest or disruptive to the stomach, pH sensitive drugs, drugs requiring a large dose can be formu ...
March 2014
... support a claim of non-inferior comparative effectiveness and safety. The PBAC noted that trial 254 was designed as a safety and tolerability trial, and did not provide sufficient basis to assess the clinical effectiveness of lurasidone compared with ziprasidone. Other trial data provided in the sub ...
... support a claim of non-inferior comparative effectiveness and safety. The PBAC noted that trial 254 was designed as a safety and tolerability trial, and did not provide sufficient basis to assess the clinical effectiveness of lurasidone compared with ziprasidone. Other trial data provided in the sub ...
N Gokal Counting the Costs
... always be relevant in our setting. Not only does the direct cost of drugs differ internationally, but the indirect costs of different drugs may also vary between populations. Variation may exist between formulation of drugs, as well as differences in the package quantity, between countries. Finally, ...
... always be relevant in our setting. Not only does the direct cost of drugs differ internationally, but the indirect costs of different drugs may also vary between populations. Variation may exist between formulation of drugs, as well as differences in the package quantity, between countries. Finally, ...
Juvenile Animal Toxicology Studies to Support Paediatric Drug
... unethical has been superseded by realisation that administration of drugs not previously tested in children may pose a greater risk than conducting studies Shift in regulatory world and specific legislation for paediatric clinical trials now in place in the US and EU Financial rewards ...
... unethical has been superseded by realisation that administration of drugs not previously tested in children may pose a greater risk than conducting studies Shift in regulatory world and specific legislation for paediatric clinical trials now in place in the US and EU Financial rewards ...
Pharmaceutical Care III Fall 2007
... taken first to open the airways and allow other types of medications to be more effectively inhaled into the lungs. Corticosteroids and cromolyn are inhaled after bronchodilating drugs. Avoid the use of over-the-counter inhalers. Most of these contain epinephrine, which is effective for only a short ...
... taken first to open the airways and allow other types of medications to be more effectively inhaled into the lungs. Corticosteroids and cromolyn are inhaled after bronchodilating drugs. Avoid the use of over-the-counter inhalers. Most of these contain epinephrine, which is effective for only a short ...
training workshop on pharmaceutical quality, good manufacturing
... Oral solutions Otic or ophthalmic solutions Topical preparations Solutions for nasal administration ...
... Oral solutions Otic or ophthalmic solutions Topical preparations Solutions for nasal administration ...
Full Text - Anesthesiology and Pain Medicine
... in the number of patients with impaired hepatic function or end stage liver disease requiring surgery. In evaluating these patients, anesthesiologists should have sufficient knowledge of the underlying disease and its impact on the performance of other organs, the risks of anesthesia and anesthetic ...
... in the number of patients with impaired hepatic function or end stage liver disease requiring surgery. In evaluating these patients, anesthesiologists should have sufficient knowledge of the underlying disease and its impact on the performance of other organs, the risks of anesthesia and anesthetic ...
AMPHETAMINES RATIONALE FOR INCLUSION IN PA PROGRAM
... deficit hyperactivity disorder (ADHD) and narcolepsy. The exact mechanism by which amphetamines exert their action is unknown; however amphetamines are thought to block the reuptake of norepinephrine and dopamine by the presynaptic neuron. This causes an increase in the release of these monoamines i ...
... deficit hyperactivity disorder (ADHD) and narcolepsy. The exact mechanism by which amphetamines exert their action is unknown; however amphetamines are thought to block the reuptake of norepinephrine and dopamine by the presynaptic neuron. This causes an increase in the release of these monoamines i ...
Society’s Struggle With Opium
... sulfur salts whose effects were mild and without bad effects” (Kramer 337). This could be noted as the first time a physician mentioned opium’s harmful side effects, and took extreme caution when administering it to patients. During his practice, Paracelsus also developed a gum substance that he use ...
... sulfur salts whose effects were mild and without bad effects” (Kramer 337). This could be noted as the first time a physician mentioned opium’s harmful side effects, and took extreme caution when administering it to patients. During his practice, Paracelsus also developed a gum substance that he use ...
Americas
... establish contact with drug users and provide them with kits containing sterile syringes, condoms and basic medical supplies to prevent the transmission of blood-borne diseases such as HIV/AIDS and hepatitis C. ...
... establish contact with drug users and provide them with kits containing sterile syringes, condoms and basic medical supplies to prevent the transmission of blood-borne diseases such as HIV/AIDS and hepatitis C. ...
Anti-psychotics
... Clozapine significantly more effective and patients stayed on it longer o Issues with the Study: ...
... Clozapine significantly more effective and patients stayed on it longer o Issues with the Study: ...
Histamine and Antihistaminic Agents
... 5 decades ago with the discovery that piperoxan was able to protect animals from the bronchial spasm induced by histamine. This finding was followed by the synthesis of a number of Nphenylethylenediamines with antihistaminic activities superior to piperoxan. Further traditional structure-activity st ...
... 5 decades ago with the discovery that piperoxan was able to protect animals from the bronchial spasm induced by histamine. This finding was followed by the synthesis of a number of Nphenylethylenediamines with antihistaminic activities superior to piperoxan. Further traditional structure-activity st ...
et al. - Deep learning for chemoinformatics
... studying the unexplored pharmacology of GPCRs (screening the ‘transducerome’) ...
... studying the unexplored pharmacology of GPCRs (screening the ‘transducerome’) ...
Hatch-Waxman Turns 30 - Yale Law School Legal Scholarship
... same time, the Hatch-Waxman Act reduced drug prices for unpatented drugs by facilitating regulatory approval of low-cost, high-quality generic prescription drugs. 2 Generic drugs are therapeutically equivalent to brand-name products made by first-entry or pioneer manufacturers. The factors defining ...
... same time, the Hatch-Waxman Act reduced drug prices for unpatented drugs by facilitating regulatory approval of low-cost, high-quality generic prescription drugs. 2 Generic drugs are therapeutically equivalent to brand-name products made by first-entry or pioneer manufacturers. The factors defining ...
Original Article Inhibitory effects of 19 antiprotozoal drugs and
... mice infected with Babesia microti. The aims of the present study were to find a preferable method for drug screening and to re-evaluate the activity of several drugs against B. microti. Methodology: The activity of 19 drugs on B. microti-infected BALB/c mice was evaluated. The study was built on Pe ...
... mice infected with Babesia microti. The aims of the present study were to find a preferable method for drug screening and to re-evaluate the activity of several drugs against B. microti. Methodology: The activity of 19 drugs on B. microti-infected BALB/c mice was evaluated. The study was built on Pe ...
Pharmaceutical industry
The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.