Biphasic Changes in Maximum Relaxation Rate during Progressive
... observations of this study. The duration of the control beats recorded at the end of 15-minute periods of reoxygenation with 95% O2-0% N2-5% CO?.. Lower traces mechanical cycle decreased substantially only when an atmosphere of 95% N2-5% CO2 was used to aerate are steady state test beats recorded 10 ...
... observations of this study. The duration of the control beats recorded at the end of 15-minute periods of reoxygenation with 95% O2-0% N2-5% CO?.. Lower traces mechanical cycle decreased substantially only when an atmosphere of 95% N2-5% CO2 was used to aerate are steady state test beats recorded 10 ...
Mitophagy and mitochondrial biogenesis in atrial tissue of patients
... mitophagy is able to selectively eliminate mitochondria with the greatest DNA damage or whether it is nonselective. It is also unknown whether the DNA damage is greatest in recently replicated mtDNA, which conceivably could be more vulnerable to free radicals. The study design precluded obtaining ti ...
... mitophagy is able to selectively eliminate mitochondria with the greatest DNA damage or whether it is nonselective. It is also unknown whether the DNA damage is greatest in recently replicated mtDNA, which conceivably could be more vulnerable to free radicals. The study design precluded obtaining ti ...
Differential responses of the right ventricle to
... Mice were subjected to pulmonary artery banding (PAB), aorto-caval shunt (Shunt), or sham surgery (Control). Four weeks later, mice were functionally evaluated with cardiac magnetic resonance imaging, pressure measurements, and and results voluntary cage wheel exercise. Right ventricular hypertrophy ...
... Mice were subjected to pulmonary artery banding (PAB), aorto-caval shunt (Shunt), or sham surgery (Control). Four weeks later, mice were functionally evaluated with cardiac magnetic resonance imaging, pressure measurements, and and results voluntary cage wheel exercise. Right ventricular hypertrophy ...
Respiratory Care of the Patient with Duchenne
... End of life directives are a critical part of the anticipatory care of individuals with DMD. There is evidence that health care professionals treating individuals with DMD underestimate the quality of life of ventilator-dependent people with DMD and that they may use their own perceptions of patient ...
... End of life directives are a critical part of the anticipatory care of individuals with DMD. There is evidence that health care professionals treating individuals with DMD underestimate the quality of life of ventilator-dependent people with DMD and that they may use their own perceptions of patient ...
An Approach to Analysis of Left Ventricular Diastolic Function and
... millimeters closer to the mitral annulus. However, relocating the sample volume all the way to the level of the annulus should be avoided because the mitral A-wave duration at this site can be shorter than that measured more toward the leaflet tips.29 Occasionally, low velocity flow (L-wave) will be ...
... millimeters closer to the mitral annulus. However, relocating the sample volume all the way to the level of the annulus should be avoided because the mitral A-wave duration at this site can be shorter than that measured more toward the leaflet tips.29 Occasionally, low velocity flow (L-wave) will be ...
MR Imaging in the Electrophysiology (EP) Laboratory
... rhythm independent of the effects of antiarrhythmic-drug therapy, cardioversion or both [7]. There are other positive effects from successful CVPI including decreased size of the LA and improvement of left ventricular ejection fraction (LVEF) in patients who remain in sinus rhythm following the proc ...
... rhythm independent of the effects of antiarrhythmic-drug therapy, cardioversion or both [7]. There are other positive effects from successful CVPI including decreased size of the LA and improvement of left ventricular ejection fraction (LVEF) in patients who remain in sinus rhythm following the proc ...
Murmurs
... You might expect to hear a midsystolic click (due to the prolapse) which is mobile with different maneuvers. Maneuvers, which diminish pre-load (going from squatting to standing, Valsalva), will accentuate the click and move it closer to S1. This mobility is not found with valvular ejection clicks ( ...
... You might expect to hear a midsystolic click (due to the prolapse) which is mobile with different maneuvers. Maneuvers, which diminish pre-load (going from squatting to standing, Valsalva), will accentuate the click and move it closer to S1. This mobility is not found with valvular ejection clicks ( ...
Using the Surface Electrocardiogram to Localize the Origin of
... generated from a distant site of origin followed by spread of activation away from the focus. Some general principles related to ventricular geometry and activation governs the ECG patterns seen in VT. First, left ventricular free wall VT shows a right bundle branch block (RBBB) configuration, while ...
... generated from a distant site of origin followed by spread of activation away from the focus. Some general principles related to ventricular geometry and activation governs the ECG patterns seen in VT. First, left ventricular free wall VT shows a right bundle branch block (RBBB) configuration, while ...
PDF - Circulation
... hemochromatosis, amyloidosis, or infections. The mean age of the patients was 41.3±2.7 years. None of the patients had a reported family history of cardiomyopathy, a personal history of alcoholism, or human immunodeficiency virus infection. On endomyocardial biopsy, there was no evidence of active m ...
... hemochromatosis, amyloidosis, or infections. The mean age of the patients was 41.3±2.7 years. None of the patients had a reported family history of cardiomyopathy, a personal history of alcoholism, or human immunodeficiency virus infection. On endomyocardial biopsy, there was no evidence of active m ...
Relations between ejection fraction and ventricular - Heart
... our patients discloses that ejection fraction and end- perfectly linear over a substantial range. Deviations systolic volume index are highly correlated. For the occur mainly at the extreme regions where the ejection range of ejection fraction values of main interest (that fraction exceeds 85% and i ...
... our patients discloses that ejection fraction and end- perfectly linear over a substantial range. Deviations systolic volume index are highly correlated. For the occur mainly at the extreme regions where the ejection range of ejection fraction values of main interest (that fraction exceeds 85% and i ...
The role of NT-proBNP in the diagnostics of isolated diastolic
... measure LV filling pressures are more reliable, but also load-dependent and not useful for wide spread clinical implementation. For these reasons, simple and reliable diagnostic criteria for diastolic heart failure are lacking and a rapid non-invasive diagnostic test would be of high clinical value. ...
... measure LV filling pressures are more reliable, but also load-dependent and not useful for wide spread clinical implementation. For these reasons, simple and reliable diagnostic criteria for diastolic heart failure are lacking and a rapid non-invasive diagnostic test would be of high clinical value. ...
Ventricular free wall rupture after myocardial infarction
... a patient recovering from acute myocardial infarction experiences chest pain and cardiovascular collapse. 79 Rupture may occur in patients doing well after their first MI. Acute electromechanical dissociation (EMD) is a specific and very suggestive sign of VFWR in a patient with first MI without car ...
... a patient recovering from acute myocardial infarction experiences chest pain and cardiovascular collapse. 79 Rupture may occur in patients doing well after their first MI. Acute electromechanical dissociation (EMD) is a specific and very suggestive sign of VFWR in a patient with first MI without car ...
Pacemaker interactions induce reentrant wave dynamics
... region located in the right atrium of the heart called the sinus node. Waves emanating from the sinus node propagate through the rest of the heart leading to cardiac contraction and the pumping of blood throughout the body. These normal circumstances can become unstable leading to a variety of abnor ...
... region located in the right atrium of the heart called the sinus node. Waves emanating from the sinus node propagate through the rest of the heart leading to cardiac contraction and the pumping of blood throughout the body. These normal circumstances can become unstable leading to a variety of abnor ...
Increased Superoxide Radical with a Decrease in Vascular
... The LVH models used in this experiment were created by abdominal aortic banding, as we had previously reported,16) and the LVH had been made a chronic process that evolved from a compensatory state to heart failure. The degree of hypertrophy was assessed with the LV/BW ratio, and it turned out to be ...
... The LVH models used in this experiment were created by abdominal aortic banding, as we had previously reported,16) and the LVH had been made a chronic process that evolved from a compensatory state to heart failure. The degree of hypertrophy was assessed with the LV/BW ratio, and it turned out to be ...
Full Text
... objectives were to (1) examine baseline patient characteristics across the distribution of heart rates recorded at discharge in hospitalized patients with a primary discharge diagnosis of HF; (2) examine the association between discharge heart rate and all-cause mortality through 1 year in patients ...
... objectives were to (1) examine baseline patient characteristics across the distribution of heart rates recorded at discharge in hospitalized patients with a primary discharge diagnosis of HF; (2) examine the association between discharge heart rate and all-cause mortality through 1 year in patients ...
Arrhythmogenic right ventricular cardiomyopathy/dysplasia
... and repolarization abnormalities, arrhythmias with the left bundle branch block morphology and fibro-fatty replacement through endomyocardial biopsy. Two dimensional echo, angiography and magnetic resonance are the imaging tools for visualizing structural-functional abnormalities. Electroanatomic ma ...
... and repolarization abnormalities, arrhythmias with the left bundle branch block morphology and fibro-fatty replacement through endomyocardial biopsy. Two dimensional echo, angiography and magnetic resonance are the imaging tools for visualizing structural-functional abnormalities. Electroanatomic ma ...
The Framingham Heart Study and the epidemiology of
... that m ost Am ericans accepted early death from heart disease as unavoidable. Franklin D Roosevelt, the wartim e President of the USA from 1933 to 1945, was in no way exem pt from the epidem ic, with heart failure due to undiagnosed and later untreated risk factors.5 In this Review we describe how m ...
... that m ost Am ericans accepted early death from heart disease as unavoidable. Franklin D Roosevelt, the wartim e President of the USA from 1933 to 1945, was in no way exem pt from the epidem ic, with heart failure due to undiagnosed and later untreated risk factors.5 In this Review we describe how m ...
Changes in cardiac troponin I concentration and in stallions
... The actual half life (T1/2) of circulating cTnI is relatively short (2 hours).6 Small amounts are initially released from the cytoplasm, resulting in early diagnostic sensitivity, while cTn reaches and persists in circulation following myocardial cell necrosis due to the continual slow release and d ...
... The actual half life (T1/2) of circulating cTnI is relatively short (2 hours).6 Small amounts are initially released from the cytoplasm, resulting in early diagnostic sensitivity, while cTn reaches and persists in circulation following myocardial cell necrosis due to the continual slow release and d ...
Professional Rescuer CPR - Emergency Care and Safety Institute
... pressurized oxygen, or pneumatic (vacuum) devices. These units require familiarity with the mechanisms for their use, as well as regular maintenance and service checks (Figure 6.2). Like manual suction devices, these mechanical devices also create a vacuum that draws obstructing materials from the p ...
... pressurized oxygen, or pneumatic (vacuum) devices. These units require familiarity with the mechanisms for their use, as well as regular maintenance and service checks (Figure 6.2). Like manual suction devices, these mechanical devices also create a vacuum that draws obstructing materials from the p ...
Cardiac function in yellowfin tuna
... How the hearts of tuna maintain function across this wide range of ambient temperatures remains unknown. Studies of cardiac muscle strips in yellowfin tuna indicate that peak force increases as temperature drops from 25 to 20 °C; however, optimal and peak frequencies decrease with falling temperatur ...
... How the hearts of tuna maintain function across this wide range of ambient temperatures remains unknown. Studies of cardiac muscle strips in yellowfin tuna indicate that peak force increases as temperature drops from 25 to 20 °C; however, optimal and peak frequencies decrease with falling temperatur ...
Detection of Pulmonic and Tricuspid Valvular
... pressure pulse was normal. In this connection it is also of interest that the right atrial pressure pulse was not modified in the 4 patients with congenital left ventriculo-right atrial communications whom we have recently studied.2' In this malformation, blood is ejected into the right atrium durin ...
... pressure pulse was normal. In this connection it is also of interest that the right atrial pressure pulse was not modified in the 4 patients with congenital left ventriculo-right atrial communications whom we have recently studied.2' In this malformation, blood is ejected into the right atrium durin ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.