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Cardiac Out Put
Cardiac Out Put

...  There may be left ventricular failure or right ventricular failure or bi – ventricular failure.  Most common cause heart failure is 1. Heart Attack or Myocardial Infarction ...
Cardiovascular
Cardiovascular

... Apart from fit, but otherwise normal individuals, there's a long list of situations where sinus bradycardia occurs, including:  hypothermia;  increased vagal tone (due to vagal stimulation or e.g. drugs);  hypothyroidism;  marked intracranial hypertension;  obstructive jaundice, and even in ure ...
MP264-Ventricular Assist Device (VAD)
MP264-Ventricular Assist Device (VAD)

... implanted postcardiotomy in an approved facility*:  acute cardiogenic shock  acute myocarditis  individuals who are unable to be weaned from cardiopulmonary bypass following cardiac surgery  Bridge- to- transplant when the risk of death is imminent from left ventricular heart failure  Destinati ...
14 Heart Q
14 Heart Q

... What condition is when the ventricles are unable to pump blood efficiently due to rapid, random contraction of cardiac muscle fibers. The muscle doesn’t contract as a unit. ...
Valvular Heart Disease/Myopathy/Aneurysm
Valvular Heart Disease/Myopathy/Aneurysm

... Dyspnea ...
Heart Failure
Heart Failure

... Add spironolactone ...
31101-Review
31101-Review

... ventricular hypertrophy, right bundle branch block, or a paced QRS complex. These features, have been reported as a risk factor for ECG screening failure in the SCD[14,15]. Despite the fact that most of our patient had right bundle branch block and two had a paced ventricular complex, all passed the ...
Levosimendan infusion in newborns after corrective surgery for
Levosimendan infusion in newborns after corrective surgery for

... sensitizer agents [8], has shown preconditioning effects and positive inotropic and vasodilating properties that successfully contributed to treat congestive heart failure and postcardiotomic heart dysfunction in adults [9–11]. So far, few data exist on levosimendan use in pediatric patients, mostly ...
Muscular System Module 6: Cardiac Muscle Tissue
Muscular System Module 6: Cardiac Muscle Tissue

... Contractions of the heart (heartbeats) are controlled by specialized cardiac muscle cells called pacemaker cells that directly control heart rate. Although cardiac muscle cannot be consciously controlled, the ...
It is likely that the drinking of cold and room
It is likely that the drinking of cold and room

... not measured the rate of blood pressure changes (dP/ dt). He claims that a possible increase in dP/dt, elicited by a water-induced enhanced sympathetic drive to the heart, would increase stroke volume and thus blood pressure, which in turn would load baroreceptors to decrease heart rate. This increa ...
Warfarin - Boston Scientific
Warfarin - Boston Scientific

... where the adverse event happened is then divided by that number (“events per patient years”.) For example, if ten patients participated in a study on heart attacks for 15 years (i.e., 150 patient-years (10 x 15)), and three of them had heart attacks, there would be one heart attack for every 50 pati ...
PowerPoint プレゼンテーション
PowerPoint プレゼンテーション

... Study Overview • In this clinical trial, rosuvastatin was compared with placebo in elderly patients with systolic, ischemic heart failure • Although rosuvastatin significantly lowered levels of both low-density lipoprotein cholesterol and high-sensitivity C-reactive protein, it did not significantl ...
DATE - Clinical Drug Information
DATE - Clinical Drug Information

Survival in the OR: Anesthetic Management of the Patient with Heart
Survival in the OR: Anesthetic Management of the Patient with Heart

... Patient monitoring: Patients with continuous-flow LVADs (most current devices) have reduced peripheral pulsatility, which can make routine monitoring challenging. In most cases, automated non-invasive blood pressure cuffs will not function adequately, necessitating the placement of an arterial cathe ...
Unlocking The Key To Arrhythmias
Unlocking The Key To Arrhythmias

Pathophysiology of Heart Failure by Dr. Sarma
Pathophysiology of Heart Failure by Dr. Sarma

... • Large number of Mega trials and literature • High mortality; Several drugs and devices • A paradigm shift in understanding & Rx. • Extremely costly – huge no. of bed days ...
Clinical and electrocardiographic features
Clinical and electrocardiographic features

... HCM has a reported prevalence of 1:500 and is a substantial contributor to sudden cardiac death in young athletes. Diagnosis of HCM is made by echocardiography and defined as septal wall thickness > 15 mm in the absence of history of hypertension or other explanatory etiologies, according to Dr. Hau ...
Strength of Evidence = A - Institute for Healthcare Improvement
Strength of Evidence = A - Institute for Healthcare Improvement

... SOLVD Investigators. N Engl J Med 1992;327:685-91 SOLVD Investigators. N Engl J Med 1991;325:293-302 CONSENSUS Study Trial Group. N Engl J Med 1987;316:1429-35 ...
Heart Failure
Heart Failure

... Fluid then leaks through the engorged capillaries & permeates air spaces in the lungs. If during each heart beat the right ventricle pumps out just one more drop of blood than the left, with in 3 hours the pulmonary blood volume will have expanded by 500 mL causing Pulmonary edema & Pleural effusion ...
Electrocardiogram findings
Electrocardiogram findings

... An Electrocardiogram (ECG, EKG) is a medical device used to evaluate the heart rhythm and heart muscle damage. A Holter monitor is used to record ECG tracings continuously for 24 hours or longer to monitor the heart rate during daily activities. An echocardiogram is a test that uses sound waves to m ...
NPLEX Combination Review Cardiovascular Part 2
NPLEX Combination Review Cardiovascular Part 2

... – Back pain (above the kidney area) – No neck or arm pain, often little chest pain – These signs and symptoms cycle on a 3-5 minute rate as well ...
(ICD) for patients at risk of sudden cardiac death
(ICD) for patients at risk of sudden cardiac death

... history of myocardial infarction, coronary artery disease, left ventricular dysfunction and cardiomyopathies. Individuals with a family history of SCD or genetic defects such as long QT syndrome are also at a high risk of SCD (Lopshire & Zipes 2006). A cross-sectional Australian study investigated t ...
Tissues in the lungs
Tissues in the lungs

... the atrioventricular node and the Purkyne tissue.  Interpret and explain the electrocardiogram (ECG) traces with reference to normal and abnormal heart activity. Coordination of contraction Cardiac muscle is unique in that it can initiate its own contraction. Heart muscle is described as myogenic. ...
Differential Diagnosis and Treatment of Wide Complex
Differential Diagnosis and Treatment of Wide Complex

Print this article - Paediatrics Today
Print this article - Paediatrics Today

... to foresee the onset of CHB. The course of CHB may be asymptomatic or some warning symptoms may be noticed. The most serious include sudden death, syncope, dyspnea, dizziness, and increased fatigue (5). Other clinical manifestations of CHB must be detected by 24-hour Holter monitoring. In our patien ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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