• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
8. Cardiac Muscle Physiology
8. Cardiac Muscle Physiology

... 5. Ventricular Diastole: Relaxation of ventricles, artery back flow slams semilunar valves shut = 2nd heart sound ("dup"). Sealed Compartment again – all valves are closed. Isovolumetric ventricular relaxation: =>  pressure as volume stays the same. The AV valves then open, refilling starts – back ...
Conducting system of heart
Conducting system of heart

Dear BSH Member, On behalf of the Programme Committee of the
Dear BSH Member, On behalf of the Programme Committee of the

...  Dilated cardiomyopathy: idiopathic or specific? - Dr Joanne Simpson  Current clinical role of CMR tissue characterisation - Prof James Moon  New drugs for HF? - Dr Charlotte Manisty  Future devices for HF - Dr Stephen Pettit  Heart failure and COPD, beta-blockers and antagonists - Dr William B ...
High-intensity track and field training in a cardiac
High-intensity track and field training in a cardiac

... maximum allowable systolic blood pressure is 240 mm Hg (1), although in practice, CR staff members typically do not allow patients to reach this threshold. There are three traditional methods of calculating maximum allowable heart rate limits in conventional CR exercise programs when actual peak hear ...
automatic external defibrillators
automatic external defibrillators

... signs of a heart attack. Do not leave them alone or allow them to exert themselves while waiting for help to arrive.) Sudden Cardiac Arrest: 1. A sudden cardiac arrest is due to an electrical event--the disturbance of the heart's normal beating action. This occurs suddenly and without warning, compl ...
Primary Prevention of Sudden Cardiac Death in Patients with Heart
Primary Prevention of Sudden Cardiac Death in Patients with Heart

... after initiation of enalapril, and a lower rate of new ventricular arrhythmias compared to hydralazine-isosorbide dinitrate, in patients with predominantly mild-to-moderate HF [28]. In terms of structural pathologies, ACE inhibitor or ARB therapy can also modulate the progression of ventricular dila ...
cardiomyopathies - Canadian Cardiovascular Society
cardiomyopathies - Canadian Cardiovascular Society

... o New onset of HF of < 2 weeks duration associated with normal sized or dilated LV and hemodynamic compromises o New onset of HF of 2 weeks – 3 months duration associated with a dilated LV and new ventricular arrhythmias, second or third AV block, or failure to respond to usual care within 1-2 weeks ...
History of fall
History of fall

... disease to assess ventricular or valvular function or to detect atrial thrombus OR with exerciseinduced syncope, cardiac murmurs, or suspected intracardiac tumors (e.g. those with positional ...
The Heart
The Heart

... The Cardiac Cycle Mechanical Events of the Heart 1. Late Diastole: “Heart at rest” all chambers relaxed filling with blood (passive filling ~ 80% full). 2. Atrial Systole: atria contract, adds the last 20% of blood to ventricles (top off ventricles) Occurs after P-wave on EKG End Diastolic Volume ( ...
Preoperative levosimendan decreases mortality and
Preoperative levosimendan decreases mortality and

... receiving levosimendan. These effects persisted during the intraoperative period and the early postoperative period, and the differences were significant between the levosimendan and control groups at all timepoints (P>0.05). Three (2.4%) patients treated with levosimendan and 12 (9.6%) in the contr ...
Real-Time Kymogram Detection from Cardiac Spiral CT Scans
Real-Time Kymogram Detection from Cardiac Spiral CT Scans

... computed tomography scans of the heart”. Medical Physics, 29(7):1489-1503 [2] H. Bruder, E. Maguet, K. Stierstorfer, T. Flohr “Cardiac spiral imaging in Computed Tomography without ECG using complementary projections for motion detection” Proc. SPIE, 5032:1798-1809, May 2003. Medical Imaging 2003: I ...
PHARMACEUTICAL CARE ISSUES IN CARDIOLOGY
PHARMACEUTICAL CARE ISSUES IN CARDIOLOGY

... Treatments for Heart disease Aspirin - low-dose aspirin may be used to avoid heart attacks. However, because of side effects and risks it is not usually recommended for healthy individuals. Mainly for those with existing heart problems or previous conditions.  Digitalis - makes the heart pump hard ...
Slide 1
Slide 1

... •Perioperative use of β.B had been shown to be efficacious in reducing cardiac morbidity and mortality in high-risk patients undergoing vascular surgery. •However, acute administration of high-dose β-blockers is not recommended as recent trials have not shown its efficacy in reducing overall mortal ...
(Updated) stroke volume, regulation and heart failure
(Updated) stroke volume, regulation and heart failure

... length-tension relationship within the ventricle. • If ventricular end diastolic volume (preload) is increased, it follows that the ventricular fiber length is also increased, resulting in an increased ‘tension’ of the muscle. • Cardiac output is directly related to venous return, the most important ...
3-Heart failure in children
3-Heart failure in children

... mg/kg/day has been used in children . Captopril is used in a dosage of upto 6 mg/kg/day in divided doses. ...
Left Bundle-Branch Block
Left Bundle-Branch Block

... In patients with LBBB, pharmacologic stress imaging has been associated with fewer false-positive defects. Several studies have indicated the clinical value of pharmacologic stress MPI in patients with pre-existing LBBB.7-9 Wagdy et al7 evaluated 245 patients with LBBB who underwent thallium or sest ...
Lown-Ganong-Levine Syndrome
Lown-Ganong-Levine Syndrome

... The Lown-Ganong-Levine (LGL) syndrome is one of the pre-excitation syndromes of which Wolff-ParkinsonWhite (WPW) syndrome is the best known. In WPW syndrome there is an accessory pathway for conduction, called the Bundle of Kent, that bypasses the atrioventricular (AV) node. No such pathway has been ...
Treatment of AF: Ablation or Pharmacotherapy: Which One and When?
Treatment of AF: Ablation or Pharmacotherapy: Which One and When?

... converts AF to sinus rhythm, and is the method of choice in severely haemodynamically compromised patients with new-onset AF • Intravenous midazolam and/or propofol. Continuous monitoring of blood pressure and oximetry during the procedure is important. Intravenous atropine or isoproterenol, or temp ...
IschemicaHy Mediated Sustained Monomorphic Ventricular
IschemicaHy Mediated Sustained Monomorphic Ventricular

Structures of the Heart - California Health Information Association
Structures of the Heart - California Health Information Association

Brugada Syndrome - UC Irvine`s Department of Medicine
Brugada Syndrome - UC Irvine`s Department of Medicine

... Autosomal dominant inheritance 20-30% of cases have anbl SCN5A gene. ...
Cardiorenal Syndrome: An Overview - The Association of Physicians
Cardiorenal Syndrome: An Overview - The Association of Physicians

... involves longer hospital stays, higher hospital costs, higher inhospital mortality rates and more readmissions but still the prognosis is grave. Earlier use of slow high-dose intravenous diuretics, dialysis with ultrafiltration for treatment of congestion, inotropes and left ventricular assistant de ...
Heart failure traffic lights
Heart failure traffic lights

... The Heart Failure Nottinghamshire Lights Scope and Purpose The purpose of the Heart Failure Nottinghamshire Lights is to provide local clinical and service guidance for General Practitioners and practicebased staff on the management of people diagnosed with heart failure. The Heart Failure Nottingh ...
Preoperative Stabilization
Preoperative Stabilization

...  May worsen ductal dependent lesions by speeding up closure of the PDA ...
Use of the “Minnesota Living with Heart Failure Questionnaire
Use of the “Minnesota Living with Heart Failure Questionnaire

... Ahmeti A, Ibrahimi P, Bytyçi I et al. Use of the “Minnesota Living with Heart Failure Questionnaire” Quality of Life Questionnaire in Kosovo’s Heart Failure Patients. International Cardiovascular Forum Journal 2016;9:36-40. DOI: 10.17987/icfj.v9i0.390 ...
< 1 ... 524 525 526 527 528 529 530 531 532 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report