new strategies for treatment of serious
... The most common classification system for antiarrhythmic drugs is the Vaughan-Willams classification scheme. In this scheme, there are four major classes of drugs. Many drugs act by more than 1 major mechanism of action. Other drugs are not well accounted for by this classification system, including ...
... The most common classification system for antiarrhythmic drugs is the Vaughan-Willams classification scheme. In this scheme, there are four major classes of drugs. Many drugs act by more than 1 major mechanism of action. Other drugs are not well accounted for by this classification system, including ...
Modern Left Ventricular Assist Devices (LVAD) : An Intro
... An LVAD is a pump that is connected to the left ventricular at, or near the apex and to the ascending aorta. It continuously pumps blood from the left ventricle to the rest of the body. ...
... An LVAD is a pump that is connected to the left ventricular at, or near the apex and to the ascending aorta. It continuously pumps blood from the left ventricle to the rest of the body. ...
The PQRSTs of ECGs
... electrodes distal to the elbow on the forelimbs and distal to the stifle on the hind limbs. This allows for less interference from movement of the core of the body. I usually apply all the electrodes first then apply the alcohol or conduction gel to each electrode. The more skin in the alligator cli ...
... electrodes distal to the elbow on the forelimbs and distal to the stifle on the hind limbs. This allows for less interference from movement of the core of the body. I usually apply all the electrodes first then apply the alcohol or conduction gel to each electrode. The more skin in the alligator cli ...
THE CARDIOVASCULAR SYSTEM
... transposition of the great arteries is true EXCEPT a. It is the primary cause of death from cyanotic congenital heart disease in the first year of life b. Congestive heart failure occurs by 4 months of age when a VSD is present c. A VSD, PDA, and/or an ASD must be present for the newborn to survive ...
... transposition of the great arteries is true EXCEPT a. It is the primary cause of death from cyanotic congenital heart disease in the first year of life b. Congestive heart failure occurs by 4 months of age when a VSD is present c. A VSD, PDA, and/or an ASD must be present for the newborn to survive ...
I P
... by Celladon Corporation. The vector in MYDICAR® is a virus made from adenoassociated virus (AAV) and the human gene SERCA2a. The AAV virus is not known to cause disease in humans. AAV is also replication defective, which means that it cannot duplicate without the presence of a helper virus. In addit ...
... by Celladon Corporation. The vector in MYDICAR® is a virus made from adenoassociated virus (AAV) and the human gene SERCA2a. The AAV virus is not known to cause disease in humans. AAV is also replication defective, which means that it cannot duplicate without the presence of a helper virus. In addit ...
Psychophysiological concepts of stress induced cardiomyopathy with broken heart syndrome
... tient, frequently postmenopausal women, is referred to the department of cardiology due to strong suspicion of myocardial infarction (STelevation) or acute coronary syndrome without concomitant stenoses and – at the most – slight elevation of the cardiac laboratory panel. The Japanese name takotsubo ...
... tient, frequently postmenopausal women, is referred to the department of cardiology due to strong suspicion of myocardial infarction (STelevation) or acute coronary syndrome without concomitant stenoses and – at the most – slight elevation of the cardiac laboratory panel. The Japanese name takotsubo ...
A&P Chapter 16
... The greater the tension of the cardiac muscle prior to contraction, the greater the force of the contraction & the more blood that is expelled. Known as the Frank-Starling Law of the Heart. Contractility: Strength of the contraction is enhanced by positive inotropic factors and decreased by negati ...
... The greater the tension of the cardiac muscle prior to contraction, the greater the force of the contraction & the more blood that is expelled. Known as the Frank-Starling Law of the Heart. Contractility: Strength of the contraction is enhanced by positive inotropic factors and decreased by negati ...
Corporate Medical Policy External Defibrillators
... systemic infection) is being clinically managed. Once treatment is completed, the permanent ICD should be implanted. For bridging after myocardial infarction (MI), the data confirm the decrease in sudden cardiac arrest for those patients considered high-risk for ventricular arrhythmias. These patien ...
... systemic infection) is being clinically managed. Once treatment is completed, the permanent ICD should be implanted. For bridging after myocardial infarction (MI), the data confirm the decrease in sudden cardiac arrest for those patients considered high-risk for ventricular arrhythmias. These patien ...
Current standards in disease management
... reducing hospitalisations can be highly important to patients and health care systems Treatment effectiveness at slowing or preventing progressive worsening of disease can be determined by reductions in the rates of both hospital admissions and mortality. Green indicates a class I recommendation; ye ...
... reducing hospitalisations can be highly important to patients and health care systems Treatment effectiveness at slowing or preventing progressive worsening of disease can be determined by reductions in the rates of both hospital admissions and mortality. Green indicates a class I recommendation; ye ...
CELLULAR RESPONSES OF THE MYOSIN
... Sprague-Dawley rats and rats with defined HF. Cellular contractility was quantified using edge detection and the calcium transient measured using fura-2 loaded myocytes. CK-0689705 increased contractility in a dose dependent manner with no significant increases in the calcium transient. In contrast, ...
... Sprague-Dawley rats and rats with defined HF. Cellular contractility was quantified using edge detection and the calcium transient measured using fura-2 loaded myocytes. CK-0689705 increased contractility in a dose dependent manner with no significant increases in the calcium transient. In contrast, ...
Apelin in acute myocardial infarction and heart failure induced by
... been shown that acute apelin administration causes NO-mediated arterial vasodilation, but does not appear to affect peripheral venous tone [36]. Our previous studies provided information that in low risk ST-elevation myocardial infarction patients, treated with primary percutaneous coronary interven ...
... been shown that acute apelin administration causes NO-mediated arterial vasodilation, but does not appear to affect peripheral venous tone [36]. Our previous studies provided information that in low risk ST-elevation myocardial infarction patients, treated with primary percutaneous coronary interven ...
Trial protocol
... The protocol continued until one of several endpoints was reached. These included if the patient achieved the target HR [85% of their age-predicted maximal HR = (220 − age) × 85%)]. The exercise was terminated in following conditions: developed severe chest pain, fatigue, leg discomfort or dyspnea; ...
... The protocol continued until one of several endpoints was reached. These included if the patient achieved the target HR [85% of their age-predicted maximal HR = (220 − age) × 85%)]. The exercise was terminated in following conditions: developed severe chest pain, fatigue, leg discomfort or dyspnea; ...
Proceedings of the British Cardiac Society - Heart
... year to a total of five years. He will represent the Society at home and abroad and will preside over meetings of the Council but not at the Scientific Meetings of the Society for which a local Chairman will be elected for each meeting.' Rule 5 to read: 'The Society shall consist of Ordinary and Ext ...
... year to a total of five years. He will represent the Society at home and abroad and will preside over meetings of the Council but not at the Scientific Meetings of the Society for which a local Chairman will be elected for each meeting.' Rule 5 to read: 'The Society shall consist of Ordinary and Ext ...
NEWSLETTER Summer 2014 Inside this Issue: www.incanursing.ie
... Hotel Kilmainham, Dublin 8. It is a relaxed evening with an opportunity to meet like minded people interested in cardiovascular nursing. There will be light refreshments and interesting presentations. All are welcome. Unfortunately we have had some committee members leave and I would like to take th ...
... Hotel Kilmainham, Dublin 8. It is a relaxed evening with an opportunity to meet like minded people interested in cardiovascular nursing. There will be light refreshments and interesting presentations. All are welcome. Unfortunately we have had some committee members leave and I would like to take th ...
Cardiotonic activity of ethanolic extract of leavesof Moringa oleifera
... mortality (Satoskar R S, 2005). Chronic heart disease ultimately leads to heart failure (HF), and the incidence of HF increases with age (Rosamond, 2007). Inotropic therapy to enhance car-diac contractile function for HF is still a significant component of the management of HF over decades (Katz et ...
... mortality (Satoskar R S, 2005). Chronic heart disease ultimately leads to heart failure (HF), and the incidence of HF increases with age (Rosamond, 2007). Inotropic therapy to enhance car-diac contractile function for HF is still a significant component of the management of HF over decades (Katz et ...
W J Paulus and D L Brutsaert 1980;46:303-304 doi: 10.1161/01.RES.46.2.303
... In such studies not only the loading of the muscles is important but also the type of experiments performed. An example of one of the experiments we had in mind when we stated in our part of the controversy (Elzinga and Westerhof, 1979) "... i.e. to study isolated heart muscle as if it were part of ...
... In such studies not only the loading of the muscles is important but also the type of experiments performed. An example of one of the experiments we had in mind when we stated in our part of the controversy (Elzinga and Westerhof, 1979) "... i.e. to study isolated heart muscle as if it were part of ...
Cardiac output and PiCCO technology - Clinical View
... the tip of the PiCCO catheter in the artery. A curve of the temperature change over time is displayed in the C.O. View of the patient monitor. This is called a thermodilution curve, see Figure 1. C.O. is calculated by using the formula of Stewart-Hamilton from the average of the selected/approved th ...
... the tip of the PiCCO catheter in the artery. A curve of the temperature change over time is displayed in the C.O. View of the patient monitor. This is called a thermodilution curve, see Figure 1. C.O. is calculated by using the formula of Stewart-Hamilton from the average of the selected/approved th ...
South African Heart Association
... ASSA’s vision to improve the care of patients by promoting research, education and training as well ...
... ASSA’s vision to improve the care of patients by promoting research, education and training as well ...
Waves and Measurements
... • Before the atria can contract, an electrical current must first stimulate the muscle cell. • For a myocardial cell to contract it must first receive an electrical stimulus. • During each phase of the cardiac cycle, a distinct pattern is produced on the EKG graph paper. ...
... • Before the atria can contract, an electrical current must first stimulate the muscle cell. • For a myocardial cell to contract it must first receive an electrical stimulus. • During each phase of the cardiac cycle, a distinct pattern is produced on the EKG graph paper. ...
ECG Dysrhythmias
... ECG Rhythm Strip Electrocardiogram or ECG is used to measure the activity of the heart ECG is used to represent the conduction of electrical impulses from the atria to the ...
... ECG Rhythm Strip Electrocardiogram or ECG is used to measure the activity of the heart ECG is used to represent the conduction of electrical impulses from the atria to the ...
TREATMENT OF HEART FAILURE UNDER CURRENT GUIDELINES
... including diuretics and ACE inhibitors, unless there is a contraindication. ...
... including diuretics and ACE inhibitors, unless there is a contraindication. ...
Cow Heart Lab - dsapresents.org
... 2) With your group, determine which side of the cow heart you have. 3) Try to determine what areas of the heart you can identify. Working with other groups can help you figure out what portion of the cow heart you have. Discussion 4) Which part of the cow heart did your group have? How do you know? ...
... 2) With your group, determine which side of the cow heart you have. 3) Try to determine what areas of the heart you can identify. Working with other groups can help you figure out what portion of the cow heart you have. Discussion 4) Which part of the cow heart did your group have? How do you know? ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.