• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
PowerPoint-presentatie - pace
PowerPoint-presentatie - pace

... • There are many causes of HF that result in ventricular remodeling, reduction of the left ventricular ejection fraction, and neurohumoral imbalance. ...
Art. 1.1475/ringraziamenti - European Review for Medical and
Art. 1.1475/ringraziamenti - European Review for Medical and

... many patients with abnormal ventricular systolic function on imaging studies are asymptomatic and do not necessarily have the clinical syndrome of HF3. While a number of disease management approaches ranging from nursing-based interventions to technological interventions using implantable hemodynami ...
Atrial Septal Defect and the CardioSEAL™ Device
Atrial Septal Defect and the CardioSEAL™ Device

... until tissue grows over it. HISTORY: The CardioSEAL™ device is the second generation of the Clamshell Occluder. The Clamshell was tested in over 700 patients since 1989 and has successfully closed various heart defects, including ASD. Over time, it was discovered that one or more of the Clamshell’s ...
CARDIAC MURMURS: DO YOU HEAR WHAT I HEAR?
CARDIAC MURMURS: DO YOU HEAR WHAT I HEAR?

... The cardiac cycle may be described as follows: Systole The atrioventricular valves (AV), the mitral and tricuspid valves close as the right and left ventricles contract to forcefully propel blood out of the heart to the lungs via the pulmonary artery (right ventricle) and to the body via the aorta ( ...
Definition and Classification of Shock
Definition and Classification of Shock

... Definition of Shock Shock is an acute clinical syndrome initiated by ineffective perfusion, resulting in severe dysfunction of organs vital to survival. Shock is not a synonym to hypotension! ...
Mechanical Properties of the Heart Contractility Cardiac Cycle
Mechanical Properties of the Heart Contractility Cardiac Cycle

... through L-type Ca2+ channels - the linkage between activated Ltype Ca2+ channels (Cav1.2, dihydropyridine receptors) in the Ttubule membrane and the Ca2+ release channels is mechanical and does not require Ca2+ entry per se  Cardiac contraction has an absolute requirement for Ca2+ influx ...
Echocardiography - Eastern Washington University
Echocardiography - Eastern Washington University

... Flow (blue) ...
A novel treatment strategy of new onset atrial fibrillation after cardiac
A novel treatment strategy of new onset atrial fibrillation after cardiac

... Postoperative atrial fibrillation (AF) is the most common complication after cardiac surgery, which occurs in up to 74% of patients who underwent on-pump and off-pump procedures [1,2]. Furthermore, it may contribute to longer hospital stays which can be associated with deterioration in heart failure ...
Transcutaneous Pacing for Pacing
Transcutaneous Pacing for Pacing

Definition and Classification of Shock
Definition and Classification of Shock

... Definition of Shock Shock is an acute clinical syndrome initiated by ineffective perfusion, resulting in severe dysfunction of organs vital to survival. Shock is not a synonym to hypotension! ...
Heart Conditions - Children`s Health Center
Heart Conditions - Children`s Health Center

... the lungs. This creates a heart murmur. According to KidsHealth.org, ASD can be genetic, but many cases have no single identifiable cause. Treatment depends on where the hole is in the septum and how big it is. Very small defects can heal on their own, but most children with this condition require s ...
Blood-Device Interactions
Blood-Device Interactions

... a. Bundle of His b. Purkinje fibers c. Atrio-ventricular node d. Sino-atrial node 22. When a patient requires pacing of three chambers of the heart, the pacing device most often used to manage cardiac stimulation and heart function is called _ICD_____. ...
Irregular Heart Beat - The Bollinger Group
Irregular Heart Beat - The Bollinger Group

... or paroxysmal (comes and goes). If it is constant, it can be seen in the electrocardiogram (ECG). However, a 24 hour Holter monitor may be necessary for further evaluation. Some of the common types of irregular heart beats are discussed below. Sinus arrhythmia is the variation of heart rhythm with b ...
CIL-03_Passen - Advocatehealth.com
CIL-03_Passen - Advocatehealth.com

... requires additional training and an advanced level of competency. Moreover, image analysis from multiple planes by the cardiologist or cardiac surgeon guides management of complex cardiac conditions. In this case: ...
Chronic Angina Pectoris - International Neuromodulation Society
Chronic Angina Pectoris - International Neuromodulation Society

Outcome of Patients with Haemodynamically Stable Ventricular
Outcome of Patients with Haemodynamically Stable Ventricular

... Introduction: The benefit of implantable cardioverter defibrillator (ICD) therapy in patients with haemodynamically stable ventricular tachycardia (VT) is not well documented. Methods: In this single-centre observational study, we examined the medical records of 53 patients (48 men, mean age 66 ± 1 ...
CSI 201 - Skills Lab #4: Arrhythmia Interpretation and Treatment
CSI 201 - Skills Lab #4: Arrhythmia Interpretation and Treatment

... (pain, valsalva, cord injury) , after an acute MI involving the right coronary artery (supplies blood to the SA node), hyperkalemia, treatment with beta blockers, Ca2+ channel blockers, sympatholytic drugs, digitalis, morphine, or demerol. Signs & Symptoms: pulse, 60, fatigue, lightheadedness, synco ...
Document
Document

... Mechanism of cardiomyocyte activity 1 Three cations present in both extra- and intracelular fluid participate in electrical activity of heart muscle: Na+, K+ and Ca2+. Na+ and Ca2+ are present mainly in ECF (Ca2+ also in endoplasmic reticulum) , K+ in ICF During fast depolarisation of a cardiomyoc ...
Internal Medicine Board Review: Cardiology Acute Coronary
Internal Medicine Board Review: Cardiology Acute Coronary

... risk with a normal EKG and a normal exercise EKG can be discharged without coronary angiography • Immediate coronary angiography would be appropriate if there were high risk markers: ...
EHRA Accreditation Exam in Cardiac Pacing
EHRA Accreditation Exam in Cardiac Pacing

... a.-Patients are analysed in the groups they were randomised to, regardless of whether they complied with the treatment given b.-Patients are analysed in the groups they were randomised to, only if they were actually receiving treatment c.-Patients are analysed in the groups they were randomised to, ...
Cost/utility analysis (CUA)
Cost/utility analysis (CUA)

... A probabilistic Markov model has been developed to extrapolate the findings of the Valsartan Heart Failure Trial (Val-HeFT) and apply them to the Italian population. The Markov model has 4 states, corresponding to NYHA classes II, III, and IV, and to death (Fig. 1). The total time of the simulation ...
Safety and Feasibility of Contrast Echocardiography for€LVAD
Safety and Feasibility of Contrast Echocardiography for€LVAD

... identification of severe right ventricular systolic dysfunction, and intensification of anticoagulation therapy in 1 patient after identification of a previously unrecognized nonobstructive left ventricular apical thrombus adjacent to the LVAD inflow cannula (Fig. 1, Online Video 1). No adverse events o ...
Cases for Heart Failure Pathophysiology Seminar
Cases for Heart Failure Pathophysiology Seminar

... pressure dropped? Has her valve stenosis changed? ...
circadian variability of rate-pressure product in essential
circadian variability of rate-pressure product in essential

... nifedipine. The decrease in blood pressure in morning hours during the enalapril treatment is accompanied by a lower heart rate increase as indicated by the decrease of rate-pressure product after enalapril treatment in comparison to nontreated patients. The relatively low increase in rate-pressure ...
Chapter Objectives - Website of Neelay Gandhi
Chapter Objectives - Website of Neelay Gandhi

... Cardiac performance deals with preload. Changing the preload will cause an increased work. Cardiac contractility deals with a shift in the cardiac output curve. This means that there will be increased work at the same preload. See pg. 45 for graph. Afterload: See question 6 9. Explain how changes in ...
< 1 ... 445 446 447 448 449 450 451 452 453 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report