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Implantable Cardioverter-Defibrillator
Implantable Cardioverter-Defibrillator

... • The response by the pacemaker is to either trigger or inhibit a pacing stimulus, depending on the absence or presence, respectively, of atrial or ventricular conduction, separately or in combination, relative to the range of heart rates that are programmed into the pacer. A commonly used mode of p ...
Voluntary exercise and testosterone therapy caused increase in
Voluntary exercise and testosterone therapy caused increase in

... Results:In left ventricles of the testosterone groups, we observed a mild but significant increase in the percentage of Myh6 myosin heavy chain isoform and higher expression of NADPH oxidase subunit Cybb (*p < 0.05). Conclusions:Testosterone affected the expression of genes related to contractile ap ...
Understanding Heart Failure
Understanding Heart Failure

... 3. Right Heart Failure: when the right heart is not able to squeeze strong enough for blood to go into the lungs a. mostly occurs when the pressure in the lungs (called pulmonary hypertension) is increased b. the most commonly due to systolic or diastolic heart failure in the left heart c. can also ...
Cardiac Pacing in First-Degree Atrioventricular Block
Cardiac Pacing in First-Degree Atrioventricular Block

... block with symptoms similar to those of pacemaker syndrome or hemodynamic compromise.” It would seem more prudent at this juncture to consider the initial implantation of a biventricular DDD device when the LV ejection fraction is ≤ 35% even in the presence of a narrow QRS complex. The guidelines of ...
VIRAL MYOCARDITIS AN UPDATE
VIRAL MYOCARDITIS AN UPDATE

... (NK) cells, which lyse infected myocytes. This helps clear the virus from the system. ...
Cardiac anatomy and physiology
Cardiac anatomy and physiology

... RELATIONSHIP BETWEEN P & QRS (HOW DO WE KNOW THIS…. WIDE QRS) PR – NO PATTERN QRS – WIDE ...
Atrioventricular Valve Endocardiosis
Atrioventricular Valve Endocardiosis

... • Low levels of sodium in the blood (known as “hyponatremia”) may develop as congestive heart failure progresses and in pets fed severely salt (sodium)–restricted diets in conjunction with medications to remove excess fluid from the body (known as “diuretics”) and certain heart medications (angioten ...
The Heart of the matter!
The Heart of the matter!

... The heart is divided into 4 chambers and each chamber has a one way valve at it’s exit that prevents blood from flowing backwards. When the heart muscle contracts or beats (called systole), it pumps blood out of the heart. The heart contracts in two stages. In the first stage, the right and left atr ...
Pseudoaneurysm of the Left Ventricle following Mitral Valve
Pseudoaneurysm of the Left Ventricle following Mitral Valve

... Unlike true aneurysms whose wall is composed of myocardium or its fibrous tissue replacement, pseudoaneurysms are retained by pericardium or extracardiac tissue. They communicate with the ventricular lumen through a small channel representing the site of previous myocardial dehiscence. The formation ...
Patho Ch12
Patho Ch12

...  Associated with chronic coronary atherosclerosis, acute plaque change, and superimposed thrombosis o Subendocardial (nontransmural) Infarction  Subendocardial zone is least perfused > most vulnerable  Typically involves inner 1/3 of ventricular wall  Can be initial stages of transmural infarcti ...
sample pdf - Fast Facts
sample pdf - Fast Facts

... investigated and managed, using both pharmacological and nonpharmacological approaches. A final chapter covers pacemakers and implantable cardioverter defibrillators, the mainstay of therapy for patients with bradyarrhythmias, heart failure requiring biventricular pacing and ventricular tachyarrhyth ...
Electrocardiography Case Studies: Review Questions
Electrocardiography Case Studies: Review Questions

... ST-/T-wave changes: nonspecific Diagnosis: atrial flutter with 4:1 conduction; nonspecific ST-and T-wave abnormalities Discussion: This 71-year-old woman presents with increasing dyspnea on exertion and is diagnosed with congestive heart failure, which is commonly associated with many supraventricul ...
Atrial Fibrillation - Anticoagulation Europe
Atrial Fibrillation - Anticoagulation Europe

... If you are healthy and your heart is working normally you are likely to have a regular resting heart rate of around 60 to 90 beats per minute. If you are experiencing atrial fibrillation (AF), however, you may notice your heartbeat becoming irregular and speeding up for no apparent reason. These fee ...
Right ventricular free wall dyskinesis in the setting
Right ventricular free wall dyskinesis in the setting

... diagnosis of arrythmogenic RV dysplasia, there were no other clinical or electrocardiographic features supportive of this diagnosis. While the significance of RV involvement in LVNC is yet unknown given the paucity of existing literature, this report serves to highlight the vast heterogeneity within ...
A Tale of Two "Pulseless Electrical Activity" Cardiac Arrest Rhythms
A Tale of Two "Pulseless Electrical Activity" Cardiac Arrest Rhythms

... It is important to distinguish between the "true" and "pseudo" subtypes of PEA. In true PEA, cardiac electrical activity in the form of a rhythm is noted, yet absolutely no mechanical contraction of the heart is occurring--hence, the absence of pulse and perfusion. Pseudo PEA, which occurs when card ...
Pause-dependent polymorphic ventricular tachycardia
Pause-dependent polymorphic ventricular tachycardia

... on therapy was 22 days (range 6 to 107 days) for dofetilidetreated patients and 99 days (range 34 to 207 days) for patients on placebo. The 15 late events included 12 cases of pause-dependent PVT and three late cases of documented TdP, two during treatment with dofetilide (days 8 and 289) and one on ...
1 - cloudfront.net
1 - cloudfront.net

... Cardiac muscle cells are long, branched, and contain 1-2 nuclei ii. Sarcomeres contain actin & myosin myofilaments forming myofibrils and are responsible for striated appearance & muscle contraction iii. Intercalated disks (“insertion between two others”) join adjacent cells and contain gap junction ...
cardiac movement identified on prehospital echocardiography
cardiac movement identified on prehospital echocardiography

... performed EE during a rhythm and pulse check. To avoid artificial movement of the valvular structures of the heart, mechanical ventilation was held during EE. While a single subxiphoid, four-chamber view was required for study enrollment, physicians were allowed to perform multiple EE examinations. ...
AV block - Livemedia
AV block - Livemedia

... • The situation may become even more complex when the conduction disturbance is intermittent ...
External Printer Options for the ZOOM
External Printer Options for the ZOOM

... CRT-P System from Boston Scientific – Contak Renewal TR Indications The CONTAK RENEWAL TR pulse generator is indicated for patients who have moderate to severe heart failure (NYHA Class III/IV) including left ventricular dysfunction (EF ≤ 35%) and QRS duration ≥ 120 ms and remain symptomatic despite ...
Defining Diastolic Dysfunction
Defining Diastolic Dysfunction

... For instance, it is now clear that the majority of patients with what is currently called “systolic heart failure” also have diastolic dysfunction of various degrees. In fact, there is some evidence9 –11 that much of the pathophysiological derangement in patients with advanced systolic heart failure ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... of accidents per driver-year in the general public. The most common cause of syncope while driving was neurally mediated syncope (37.3%). The next most common identifiable causes were cardiac arrhythmias, including bradyarrhythmias, ventricular tachyarrhythmias, and supraventricular tachyarrhythmias ...
5D MRI - Cardiac and respiratory time-resolved volume imaging
5D MRI - Cardiac and respiratory time-resolved volume imaging

... The pulse sequence was modified to utilize a view-order-selection scheme extending the TRIADS[2] approach. Realtime histogram equalization was used to estimate the respiratory time-frame to be acquired (8 time-frames were resolved) and the average of the last 3 RR-intervals was used to determine cur ...
Causes of sudden death in athletes less than 35
Causes of sudden death in athletes less than 35

... Physical examination: heart murmurs, arrhythmias, femoral artery puls (coarctation of aorta), Marfan syndrome ...
Effect of Cardiac Rehabilitation on Cardiovascular Events after
Effect of Cardiac Rehabilitation on Cardiovascular Events after

... survival after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). Furthermore, CR can enhance peak VO2; alleviate dyspnea or fatigue symptoms; improve oxygen utilization and quality of life; and reduce sympathetic tone [8,9]. Recently, most studies have reported tha ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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