Bonita MB Porter, B.Sc., Phm., B.Sc., MD, CCFP Chief Coroner for
									
... ascertained following scene investigation and complete autopsy, as well as ancillary testing. In a small portion of medico-legal cases, however, a cause of death may not be found. Recent molecular research has found that in such deaths, with negative findings at autopsy, many of the decedents, or th ...
                        	... ascertained following scene investigation and complete autopsy, as well as ancillary testing. In a small portion of medico-legal cases, however, a cause of death may not be found. Recent molecular research has found that in such deaths, with negative findings at autopsy, many of the decedents, or th ...
									2. Acute coronary syndromes
									
... Exercise tolerance test (ETT)  Of choice when patient can ambulate  Can do without imaging if no baseline ECG abnormalities (digoxin effect, LVH, LBBB, paced, WPW, ST abnormalities associated with SVT, atrial fibrillation, mitral valve prolapse, severe anemia). RBBB okay for ECG interpretation  A ...
                        	... Exercise tolerance test (ETT)  Of choice when patient can ambulate  Can do without imaging if no baseline ECG abnormalities (digoxin effect, LVH, LBBB, paced, WPW, ST abnormalities associated with SVT, atrial fibrillation, mitral valve prolapse, severe anemia). RBBB okay for ECG interpretation  A ...
									Atrial fibrillation and outcomes in heart failure with preserved versus
									
... diagnoses and relevant imaging results for 2005–2008 from 4 health plans in the Cardiovascular Research Network. Data on demographic features, diagnoses, procedures, outpatient pharmacy use, and laboratory results were ascertained from health plan databases. Hospitalizations for HF, stroke, and any ...
                        	... diagnoses and relevant imaging results for 2005–2008 from 4 health plans in the Cardiovascular Research Network. Data on demographic features, diagnoses, procedures, outpatient pharmacy use, and laboratory results were ascertained from health plan databases. Hospitalizations for HF, stroke, and any ...
									Atrial Fibrillation, the Arrhythmia of the Elderly
									
... Whether AF is facilitated by heart failure or heart failure is precipitated by AF is not always easy to determine in an individual patient (the chicken and egg dilemma). In Middlekauf et al. study (20), left ventricular ejection fraction was significantly higher (p< 0.04) in the AF group (0.21±0.04) ...
                        	... Whether AF is facilitated by heart failure or heart failure is precipitated by AF is not always easy to determine in an individual patient (the chicken and egg dilemma). In Middlekauf et al. study (20), left ventricular ejection fraction was significantly higher (p< 0.04) in the AF group (0.21±0.04) ...
									ecg-arryhthmias
									
... • The Q-T interval represents the time for both ventricular depolarization and repolarization to occur, and therefore roughly estimates the duration of an average ventricular action potential. This interval can range from 0.2 to 0.4 seconds depending upon heart rate. At high heart rates, ventricular ...
                        	... • The Q-T interval represents the time for both ventricular depolarization and repolarization to occur, and therefore roughly estimates the duration of an average ventricular action potential. This interval can range from 0.2 to 0.4 seconds depending upon heart rate. At high heart rates, ventricular ...
									Adults with repaired tetralogy: low mortality but high morbidity up to
									
... Fallot (ToF) were included if they were ≥16 and had been seen at least twice since January 2000. This was a retrospective review of prospectively collected data. Patients with other congenital defects or with more complex variants of ToF, including pulmonary atresia with ventricular septal defect (P ...
                        	... Fallot (ToF) were included if they were ≥16 and had been seen at least twice since January 2000. This was a retrospective review of prospectively collected data. Patients with other congenital defects or with more complex variants of ToF, including pulmonary atresia with ventricular septal defect (P ...
									Acute Coronary Syndrome STEMI
									
... Reperfusion is not routinely recommended in patients who present more than 12 hours after symptom onset. It may be considered however in selected cases: ...
                        	... Reperfusion is not routinely recommended in patients who present more than 12 hours after symptom onset. It may be considered however in selected cases: ...
									MS Word Version - Interactive Physiology
									
... • Initiates the depolarization impulse which, in turn, generates an action potential that spreads throughout the atria to the AV node. • Sets the overall pace of the heartbeat. Internodal Pathway • Located in the walls of the atria. • Links the SA node to the AV node. • Distributes the action potent ...
                        	... • Initiates the depolarization impulse which, in turn, generates an action potential that spreads throughout the atria to the AV node. • Sets the overall pace of the heartbeat. Internodal Pathway • Located in the walls of the atria. • Links the SA node to the AV node. • Distributes the action potent ...
									Extra-corporeal membrane oxygenation support in cardiac
									
... rate ranges from 68% to 82% and corresponds to a hospital mortality rate of 50%. [9,10]. In our transplant center the one-year survival rate for ECMO-supported PGF patients was 43% when the decision was made early to use ECMO support as a bridge to recovery. Delayed consideration for ECMO support in ...
                        	... rate ranges from 68% to 82% and corresponds to a hospital mortality rate of 50%. [9,10]. In our transplant center the one-year survival rate for ECMO-supported PGF patients was 43% when the decision was made early to use ECMO support as a bridge to recovery. Delayed consideration for ECMO support in ...
									Pacemaker Therapy and the Conducting System of the Heart
									
... increase or decrease the heart rhythm at an appropriate rate. • Used when the heart cannot increase its rate with activity. • Most pacemakers today are rate-responsive. ...
                        	... increase or decrease the heart rhythm at an appropriate rate. • Used when the heart cannot increase its rate with activity. • Most pacemakers today are rate-responsive. ...
									Adults with repaired tetralogy: low mortality but high morbidity up to
									
... Fallot (ToF) were included if they were ≥16 and had been seen at least twice since January 2000. This was a retrospective review of prospectively collected data. Patients with other congenital defects or with more complex variants of ToF, including pulmonary atresia with ventricular septal defect (P ...
                        	... Fallot (ToF) were included if they were ≥16 and had been seen at least twice since January 2000. This was a retrospective review of prospectively collected data. Patients with other congenital defects or with more complex variants of ToF, including pulmonary atresia with ventricular septal defect (P ...
									Full PDF - Acta Veterinaria
									
... in around 2.9 - 3.5% of the otherwise healthy general horse population and the prevalence is much higher in racing Thoroughbreds [1,2,7]. Generally, large horses have larger cardiac dimensions than smaller animals, and fit, athletic horses have larger chambers compared to horses which are not traine ...
                        	... in around 2.9 - 3.5% of the otherwise healthy general horse population and the prevalence is much higher in racing Thoroughbreds [1,2,7]. Generally, large horses have larger cardiac dimensions than smaller animals, and fit, athletic horses have larger chambers compared to horses which are not traine ...
									Rhythm disorders in neonates
									
... This arrhythmia is very common in fetuses and neonates. It is produced by increased automaticity in a group of atrial cells which are not part of the normal conduction system. In the ECG they appear as tachycardias with a narrow QRS complex and an abnormal P wave with variable morphology (migratory ...
                        	... This arrhythmia is very common in fetuses and neonates. It is produced by increased automaticity in a group of atrial cells which are not part of the normal conduction system. In the ECG they appear as tachycardias with a narrow QRS complex and an abnormal P wave with variable morphology (migratory ...
									Complications of Acute Myocardial Infarction
									
... assisted device (Fig. 2). If a major vessel causing occlusion is reperfused irrespective of the type of reperfusion therapy, the in-hospital mortality rate is less than 40%, suggesting the importance of successful reperfusion. A guideline of the ACC/AHA (American College of Cardiology/American Heart ...
                        	... assisted device (Fig. 2). If a major vessel causing occlusion is reperfused irrespective of the type of reperfusion therapy, the in-hospital mortality rate is less than 40%, suggesting the importance of successful reperfusion. A guideline of the ACC/AHA (American College of Cardiology/American Heart ...
									Shock - Hamilton Health Sciences
									
... produce some form of cardiac output. DO NOT assume that since there is a rhythm on the screen that the patient has a pulse!! ...
                        	... produce some form of cardiac output. DO NOT assume that since there is a rhythm on the screen that the patient has a pulse!! ...
									Endothelin system and atrial fibrillation post
									
... examinations as part of their clinical assessment. Apart from beta-blockade, no patient was on any antiarrhythmic medication, including amiodarone, and none had received hormone replacement therapy. Aspirin was discontinued at least 10 days prior to the scheduled operation. Patients in sinus rhythm ...
                        	... examinations as part of their clinical assessment. Apart from beta-blockade, no patient was on any antiarrhythmic medication, including amiodarone, and none had received hormone replacement therapy. Aspirin was discontinued at least 10 days prior to the scheduled operation. Patients in sinus rhythm ...
									Chapter 21 - heart - Fullfrontalanatomy.com
									
... organisms need mechanisms which mimic an external environment. This is there the cardiovascular system comes in. Most of the cells in our body are surrounded by fluid which mimics a natural environment. Capillary beds are where cells are fed. It is crucial that all cells receive what they need to su ...
                        	... organisms need mechanisms which mimic an external environment. This is there the cardiovascular system comes in. Most of the cells in our body are surrounded by fluid which mimics a natural environment. Capillary beds are where cells are fed. It is crucial that all cells receive what they need to su ...
									PDF Article
									
... Address for reprints: Abdulmassih S. Iskandrian, MD, Likoff Cardiovascular Institute, Hahnemann University, 230 North Broad Street, Philadelphia, Pennsylvania 19102. ©1986 by the American College of Cardiology ...
                        	... Address for reprints: Abdulmassih S. Iskandrian, MD, Likoff Cardiovascular Institute, Hahnemann University, 230 North Broad Street, Philadelphia, Pennsylvania 19102. ©1986 by the American College of Cardiology ...
									Managing Atrial Fibrillation 2016: Anticoagulation, Pharma and
									
... options to warfarin • Bridging therapy in high risk patients remains controversial but ...
                        	... options to warfarin • Bridging therapy in high risk patients remains controversial but ...
									Cardiac Output as a Function of Ventricular Rate in a
									
... unique opportunities to study physiologic principles relating to cardiac function that cannot be evaluated under ordinary circumstances. We recently studied a patient who had developed complete heart block without evidence of other cardiac or systemic disease. With heart rate controlled by an extern ...
                        	... unique opportunities to study physiologic principles relating to cardiac function that cannot be evaluated under ordinary circumstances. We recently studied a patient who had developed complete heart block without evidence of other cardiac or systemic disease. With heart rate controlled by an extern ...
									Systolic ventricular function – h t th l ft t i l how to assess the left
									
... – continuity equation for measuring stroke volume & continuity equation for measuring stroke volume & cardiac output. ...
                        	... – continuity equation for measuring stroke volume & continuity equation for measuring stroke volume & cardiac output. ...
									independent work of the students
									
... 3. Myocardial factors that affect the contractility of the muscle fibers, such as myocardial ischemia from severe anemia or asphyxia, heart block, acidemia, and low levels of potassium, glucose, calcium, or magnesium. 4. High cardiac output demands, in which the body's need for oxygenated blood exce ...
                        	... 3. Myocardial factors that affect the contractility of the muscle fibers, such as myocardial ischemia from severe anemia or asphyxia, heart block, acidemia, and low levels of potassium, glucose, calcium, or magnesium. 4. High cardiac output demands, in which the body's need for oxygenated blood exce ...
Cardiac contractility modulation
                        Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.