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Rx for Success - Electrocardiogram and T-wave Changes(002)
Rx for Success - Electrocardiogram and T-wave Changes(002)

... Unfavorable factors may result in a higher rating for ST segment or T-waves abnormalities. These include new changes in the ECG pattern, recent chest pain, or poor cardiac risk factors. Favorable factors may reduce the rating. These include favorable cardiac risk factors, stable ECG pattern for five ...
Utilization of Fosphenytoin for Digoxin-Induced
Utilization of Fosphenytoin for Digoxin-Induced

... This case was a 78-year-old male with digoxin toxicity who developed ventricular arrhythmias. The presence of the elevation of free digoxin with the risk of further dysrhythmia precludes the use of many traditional antiarrhythmics. This patient’s deteriorating renal function cautioned use of lidocai ...
PDF
PDF

... prior lateralized stroke. Because /3-blockers are an effective treatment for most cases of SVT,31 the greater use of /3-blockers in patients with right-sided strokes may have masked an even larger association with SVT. Supraventricular tachycardia is a heterogeneous phenomenon, the subtype of which ...
ostium primum defect: factors causing deterioration in - Heart
ostium primum defect: factors causing deterioration in - Heart

How to detect disease progression in pulmonary arterial hypertension REVIEW J-L. Vachie
How to detect disease progression in pulmonary arterial hypertension REVIEW J-L. Vachie

... (no limitation in physical activity) to IV (inability to carry out physical activity without symptoms, or with symptoms present at rest) [15, 17]. A patient presenting with signs of right heart failure (peripheral oedema, ascites and jugular vein distension) should be considered to be in WHO FC IV. ...
Print this article - International Cardiovascular Forum Journal
Print this article - International Cardiovascular Forum Journal

... The overall prognosis of TTC remains excellent, with a full recovery observed in 96% of cases although serious complications do occur, including ventricular rupture, thrombosis, arrhythmia, and chronic heart failure.8 In all three cases above, the physical stress of acute pulmonary edema likely trig ...
HEART Score
HEART Score

... abnormalities, advanced age, risk profile, and/or increased troponin levels. Each of these findings may be a separate, convincing argument for the diagnosis of ACS. With this in mind, various parameters were combined into the HEART score. The acronym is an abbreviation of the words: History, ECG, Ag ...
chapter 1: cardiology - Physician Assistant Boards
chapter 1: cardiology - Physician Assistant Boards

... ACE/ARBs and beta blockers are your main drugs in terms of lowering mortality.  Specific beta blockers you should know are carvedilol, bisoprolol, and metoprolol succinate - these have the most proven benefit in reducing mortality.  Small caveat: never give beta blockers during an acute exacerbation ...
Clinical Pharmacology of Drugs for Controlling Vascular Tone
Clinical Pharmacology of Drugs for Controlling Vascular Tone

... 3. Scheme of drug treatment should be the most availably simple – 1 tablet per day if possible; it is better to use drugs with long duration of action (prophylaxis of considerable fluctuation of blood pressure during the day). 4. Rapid decreasing of blood pressure to low figures is dangerous, especi ...
Comparative Effects of Low and High Doses of the Angiotensin
Comparative Effects of Low and High Doses of the Angiotensin

... reason (P50.002) and 24% fewer hospitalizations for heart failure (P50.002). Dizziness and renal insufficiency was observed more frequently in the high-dose group, but the 2 groups were similar in the number of patients requiring discontinuation of the study medication. Conclusions—These findings in ...
Tumor Necrosis Factor-Alpha and Inflammation
Tumor Necrosis Factor-Alpha and Inflammation

... part to the fact that the failing heart produces robust quantities of TNF-α. Indeed, low levels of TNF-α were observed in the heart of healthy individual, however, TNF-α expression were significantly increased in patients with end-stage dilated cardiomyopathy (nonischemic) and ischemic heart disease ...
Sudden Cardiac Death in Thrombotic Thrombocytopenic Purpura
Sudden Cardiac Death in Thrombotic Thrombocytopenic Purpura

... nerve system and kidney, involvement of the heart, spleen, pancreas, adrenals and other organs is well described 4. Cardiac involvement has been documented in some necropsy studies references. Furthermore, it seems that cardiac involvement in the course of TTP is a constant autopsy finding 5. It ma ...
Properties of Cardiac Muscle
Properties of Cardiac Muscle

... ‘Within limits, the greater the initial length of the fiber, the stronger will be the force of its contraction; However, overstretching the fiber as in heart failure its power of contractility decreases’ i.e. within limits, the power of contraction is directly proportional to the initial length of t ...
Influence of Ejection Fraction on Outcomes and Efficacy of Sacubitril
Influence of Ejection Fraction on Outcomes and Efficacy of Sacubitril

... IV HF with reduced EF [left ventricular EF (LVEF) ≤40%] were randomized to sacubitril/valsartan 97/103 mg twice daily versus enalapril 10 mg twice daily and followed for a median of 27 months. The primary study end point was cardiovascular death or HF hospitalization. LVEF was assessed at the sites ...
In-hosptial initiation of CVP meds
In-hosptial initiation of CVP meds

... Assess BMI and/or waist circumference on each visit and consistently encourage weight maintenance/ reduction through an appropriate balance of physical activity, caloric intake, and formal behavioral programs when indicated. If waist circumference (measured at the iliac crest) >35 inches in women an ...
Biomedical Engineering Faculty Biological System Modeling seminar
Biomedical Engineering Faculty Biological System Modeling seminar

... - Left Ventricular Assist Devices(LVADs) A left ventricular assist device(LVAD) is a battery operated, mechanical pump type device that is surgically implanted. This device is sometimes called a “bridge to transplant” . ...
A Novel Method to Reduce Heart Failure Readmissions Objectives
A Novel Method to Reduce Heart Failure Readmissions Objectives

... – Medications: ~$6/kit ...
6.2 Control of the Heart Beat
6.2 Control of the Heart Beat

... branches of the AV bundle which radiate through the walls of the ventricles, transmitting an impulse to the cells of the ventricles, causing them to contract simultaneously. ...
PDF - Romanian Journal of Cardiology
PDF - Romanian Journal of Cardiology

... LV function as assessed by transthoracic echocardiography correlated with a greater risk of sudden cardiac death or life-threatening ventricular arrhythmias.40 This finding was independent of QRS prolongation and appears to be an additional risk predictor for this patient population. In a large mult ...
A1993MH50800001
A1993MH50800001

... causes of stunning. Stunning occurs under a wide variety of clinical circumstance^.^ These include the postcardioplegic cardiac arrest period, the postcardiac transplantation state, patients with evolving myocardial infarction who have undergone reperfusion therapy, unstable angina, and Prinzmetal’s ...
Journal of the Hoffman - Saint Francis Hospital and Medical Center
Journal of the Hoffman - Saint Francis Hospital and Medical Center

... esophageal intubation. Many patients received 0.5 to 2 mg of intravenous midazolam for ...
Ventricular Septal Defect
Ventricular Septal Defect

... forcing the heart to over work, making it bigger. To prevent lung and heart problems, larger holes usually need to be fixed sometime after birth with surgery by applying a patch or by sewing the hole closed. ...
ecg-arryhthmias
ecg-arryhthmias

... • The Q-T interval represents the time for both ventricular depolarization and repolarization to occur, and therefore roughly estimates the duration of an average ventricular action potential. This interval can range from 0.2 to 0.4 seconds depending upon heart rate. At high heart rates, ventricular ...
Atrial fibrillation and outcomes in heart failure with preserved versus
Atrial fibrillation and outcomes in heart failure with preserved versus

... diagnoses and relevant imaging results for 2005–2008 from 4 health plans in the Cardiovascular Research Network. Data on demographic features, diagnoses, procedures, outpatient pharmacy use, and laboratory results were ascertained from health plan databases. Hospitalizations for HF, stroke, and any ...
2. Acute coronary syndromes
2. Acute coronary syndromes

... Exercise tolerance test (ETT)  Of choice when patient can ambulate  Can do without imaging if no baseline ECG abnormalities (digoxin effect, LVH, LBBB, paced, WPW, ST abnormalities associated with SVT, atrial fibrillation, mitral valve prolapse, severe anemia). RBBB okay for ECG interpretation  A ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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