• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Dilated Cardiomyopathy - Children`s Cardiomyopathy Foundation
Dilated Cardiomyopathy - Children`s Cardiomyopathy Foundation

... In some cases, more invasive cardiac tests may be necessary. A cardiac catheterization is the most useful and accurate tool for diagnosing cardiovascular problems. It can be used to check for blockage in the arteries, measure heart and lung pressures, evaluate the heart’s pumping ability and perform ...
CH20 Page 1-2 - Pharmacotherapy
CH20 Page 1-2 - Pharmacotherapy

... Therapeutic Alternatives5–7 3.a. What nonpharmacologic therapies may be useful for this patient? • Hemodynamically unstable patients should be treated with cardioversion immediately, with energy ranging from 100 to 360 J. 3.b. What pharmacotherapy options are available for acute treatment of TdP? ...
Peer-reviewed Article PDF - e
Peer-reviewed Article PDF - e

... subsequently into the RA) and have no hemodynamic consequences [6]. The long term clinical course of such patients is usually uneventful in the absence of other congenital heart defects. In patients with accompanying congenital heart disease, their long term course is mostly influenced by particular ...
Volume
Volume

... characterized by important involvement of compensatory mechanisms, mainly neurohumoral, which can, however, if persisting, lead to further progression of failure. Another changes involve the heart itself. Compensatory mechanisms – can in short-term have a positive role, in long-term persistence cont ...
Left Bundle Branch Block in a 29-Year-Old Non
Left Bundle Branch Block in a 29-Year-Old Non

... and reversible EKG changes [5]. These EKG changes include left ventricular hypertrophy (LVH), right bundle branch block (RBBB), sinus bradycardia, first degree atrioventricular block, and domed ST elevations. LBBB however, is not recognized as a normal EKG variant in the athlete heart. In fact, in a ...
Cardiovascular Pharmacology
Cardiovascular Pharmacology

... atria in the mechanism of the tachycardia. Many SVTs are due to extra, abnormal electrical connections between the atria and the ventricles. Individuals with SVT are often born with these extra pathways. The existence of such extra pathways (often called “bypass tracts”) allow the formation of “reen ...
Physiology of cardiovascular system lecture 1, 2 Dr.Abdul
Physiology of cardiovascular system lecture 1, 2 Dr.Abdul

Sympathetic and reflex abnormalities in heart failure secondary to
Sympathetic and reflex abnormalities in heart failure secondary to

... Congestive heart failure (CHF) is characterized by a sympathetic activation and a baroreflex impairment whose degree is directly related to the clinical severity of the disease. However, whether these abnormalities vary according to the ischaemic or idiopathic dilated nature of the CHF state has not ...
11/07 Cardiac Resynchronization Therapy
11/07 Cardiac Resynchronization Therapy

... Jessup M, Brozena S. Medical Progress--Heart Failure. N Eng J Med 2003; 348: 2007-2018. Copyright 2002 Massachusetts Medical Society. ...
Perioperative Cardiovascular Evaluation for Noncardiac Surgery
Perioperative Cardiovascular Evaluation for Noncardiac Surgery

... – Low-risk noncardiac surgery in a patient with known CAD and low-risk results on noninvasive testing – Screening for CAD without appropriate noninvasive testing – Asymptomatic after coronary revascularization, with excellent exercise capacity(>7METs) – Mild stable angina in patients with good LV fu ...
qt interval variability and qt/rr relationship in patients
qt interval variability and qt/rr relationship in patients

... interval and its adaptation to the heart rate (HR). Moreover, new methods, which may be helpful in stratification of patients (pts) being at higher risk of sudden cardiac death, are still investigated. Many papers showed that prolonged QT interval duration (QT), QT corrected to the heart rate (QTc) ...
Atrial Fibrillation in Patients with Ischemic and Non
Atrial Fibrillation in Patients with Ischemic and Non

... from HF was 10-12%, translating into an odds ratio of 4.5 in women and 5.9 in men of developing AF in the presence of HF. The attributed risk of AF from myocardial infarction was 1-5%.6 The Framingham study was the first large prospective investigation showing a clear association between HF and AF. ...
Atrial Fibrillation in Dogs
Atrial Fibrillation in Dogs

... So, what is atrial fibrillation in dogs? Atrial fibrillation is a malfunction of the heart's electrical system. Instead of the electrical impulse originating from the SA node, the impulse originates from many different areas of the right atrium in an unorganized manner. This causes the atrial tissue ...
Abnormal left ventricular diastolic function during
Abnormal left ventricular diastolic function during

... function, were normal. Cold pressor test induced the same increase in systolic and diastolic blood pressure in both groups (Table 3). The increase in heart rate was also comparable. Significant changes with prolongation of IVRT (59±5ms to 69±5ms, P=O.OOI), decrease in peak early filling (0.91 ± 0.1 ...
Early Postoperative Takotsubo Cardiomyopathy
Early Postoperative Takotsubo Cardiomyopathy

Irbesartan in Patients with Heart Failure and Preserved
Irbesartan in Patients with Heart Failure and Preserved

... in many of the processes associated with this syndrome (including hypertension, left ventricular hypertrophy, myocardial fibrosis, and vascular dysfunction),7,8 inhibitors of this system have been of particular interest as a ther­apeutic intervention for these patients.9,10 Although information abou ...
Report of the National Heart, Lung, and Blood Institute Working
Report of the National Heart, Lung, and Blood Institute Working

... autonomic nervous system activity, or salt and water control seen in such patients may have substantive effects on health and functional capacity for affected individuals (25–28). Numerous challenges face the cardiology practitioner when confronted with ACHD patients (29,30). Many patients have sequ ...
Heart Failure—Definition
Heart Failure—Definition

... • Acute: sudden onset over days or hours • Chronic: develop over months to years • If the cause of acute symptoms is not reversed, then heart failure will become chronic. ...
Crescendo in Depolarization and Repolarization
Crescendo in Depolarization and Repolarization

... reduction principle of recursive averaging; achieves an excellent signalto-noise ratio17; is relatively tolerant of nonstationary data, such as changing heart rates or motion artifact; and is independent of phase-shift perturbations.16 Respiration and motion artifacts have been further reduced by cu ...
PDF - Cardiovascular Ultrasound
PDF - Cardiovascular Ultrasound

... chronic (> 6 months) systolic heart failure (ejection fraction ≤ 35% and New York Heart Association class III to IV symptoms), who underwent a right heart catheterization, in the cardiac catheterization laboratory (n = 34) or in the intensive care unit (n = 14), because of concerns about hemodynamic ...
The Cardiac Function In The Patients With Congenital Scoliosis
The Cardiac Function In The Patients With Congenital Scoliosis

... urography.19 The exact incidence of congenital heart disease associated with congenital scoliosis has not been reported. Hensinger et al. found a 14% incidence of congenital heart disease among patients with Klippel–Feil syndrome.20 In our study, 34 patients (15.8%) had intraspinal abnormalities tha ...
ECG Waveform tip.pdf
ECG Waveform tip.pdf

... Measured from beginning of first waveform to end of last waveform in complex Duration: Less than .10 second (use .12 for ease of measurement) Significance: Ventricular depolarization time Prolonged QRS: Disturbance somewhere in conduction pathway ...
Non-cardioplegic coronary surgery in patients with severe left
Non-cardioplegic coronary surgery in patients with severe left

... days of coronary surgery for ischemic heart disease but most surgeons now use one of several forms of cardioplegia for myocardial protection during CABG. There is no doubt that cardioplegia affords good protection to the myocardium. An unlimited number of reports dealing with cardioplegia in any of ...
First Successful Management of Aortic Valve Insufficiency
First Successful Management of Aortic Valve Insufficiency

... The authors wish to thank Francesco Bedogni, MD, Department of Interventional Cardiology, S. Ambrogio Clinical Institute, Milan, Italy, for his technical assistance during the procedure. Reprint requests and correspondence: Dr. Francesco Santini, Division of Cardiac Surgery, University of Verona, O. ...
As Pa is greater then Pv atrial contraction adds to the diastolic
As Pa is greater then Pv atrial contraction adds to the diastolic

... Its duration 0.1 sec. It is some guide to the functional activity of the atrial muscle. QRS is the electrical activity aroused by invasion of the ventricle. ts duration in man 0.08 sec. The P - R interval 0.13 - 0.16 sec It represent the stage of ventricular deplarization .. The time interval from t ...
< 1 ... 398 399 400 401 402 403 404 405 406 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report