Coupled systolic-ventricular and vascular stiffening with age
... elderly (18 –20,31) that are linked to greater blood pressure sensitivity to diuretic therapy, altered fluid intake and postural or postprandial stress (21–24,31). Ventricular-vascular coupling with age. Although tandem elevation of Ees and Ea was statistically significant, there was considerable sc ...
... elderly (18 –20,31) that are linked to greater blood pressure sensitivity to diuretic therapy, altered fluid intake and postural or postprandial stress (21–24,31). Ventricular-vascular coupling with age. Although tandem elevation of Ees and Ea was statistically significant, there was considerable sc ...
Prognostic Value of a Novel Classification Scheme for Heart Failure
... over five million persons in the United States and over 23 million worldwide (1). The epidemiologic study of heart failure, however, has been partly impeded by the absence of a universally agreed-upon case definition (2–12). Though numerous case definitions have been introduced into the literature—p ...
... over five million persons in the United States and over 23 million worldwide (1). The epidemiologic study of heart failure, however, has been partly impeded by the absence of a universally agreed-upon case definition (2–12). Though numerous case definitions have been introduced into the literature—p ...
Steven Shea, Li Pan, David A. Bluemke and João A.C. Lima Thor
... Key Words: atherosclerosis 䡲 coronary circulation 䡲 calcification 䡲 MRI 䡲 myocardial function ...
... Key Words: atherosclerosis 䡲 coronary circulation 䡲 calcification 䡲 MRI 䡲 myocardial function ...
Document
... 2. have better survival over 5 yrs if ED clinicians are provided with ECG ischemia monitoring information from the field UCSF ...
... 2. have better survival over 5 yrs if ED clinicians are provided with ECG ischemia monitoring information from the field UCSF ...
1st Degree AV Block
... for sinus node dysfunction (SND) with documented symptomatic bradycardia, including frequent sinus pauses that produce symptoms. ...
... for sinus node dysfunction (SND) with documented symptomatic bradycardia, including frequent sinus pauses that produce symptoms. ...
Whole Grape Intake Impacts Cardiac Peroxisome
... the on-line supplement via http://hyper.ahajournals.org. Neither HSH nor HSG prevented the development of hypertension, but both significantly reduced systolic blood pressure relative to HS (on-line supplement Figure S3). The first statistically significant decrease versus HS was detected at 6 weeks ...
... the on-line supplement via http://hyper.ahajournals.org. Neither HSH nor HSG prevented the development of hypertension, but both significantly reduced systolic blood pressure relative to HS (on-line supplement Figure S3). The first statistically significant decrease versus HS was detected at 6 weeks ...
link
... myocardial tissue oxygen tension falls and may cause transient disturbances of the mechanical, biochemical, and electrical functions of the myocardium. Coronary atherosclerosis is a focal process that usually causes nonuniform ischemia. During ischemia, regional disturbances of ventricular contracti ...
... myocardial tissue oxygen tension falls and may cause transient disturbances of the mechanical, biochemical, and electrical functions of the myocardium. Coronary atherosclerosis is a focal process that usually causes nonuniform ischemia. During ischemia, regional disturbances of ventricular contracti ...
here
... the “true” SV (Fig. 2A). To assess the offset or parallel conductance, one can use the hypertonic saline calibration method first proposed by Baan et al. (2) and later applied and validated by our group in mice (9). This is based on the principle that if one only varies the conductivity of blood (in ...
... the “true” SV (Fig. 2A). To assess the offset or parallel conductance, one can use the hypertonic saline calibration method first proposed by Baan et al. (2) and later applied and validated by our group in mice (9). This is based on the principle that if one only varies the conductivity of blood (in ...
Unexpected Serious Cardiac Arrhythmias in the Setting of
... As a piperidine derivative, the mechanism of loperamide-induced cardiotoxicity is theorized to be due to dose-dependent effects on the voltage-gated L-type calcium channels, hERG/Ikr potassium channel and cardiac sodium channels, similar to the action of Vaughan-Williams class 1A, III, and IV anti-a ...
... As a piperidine derivative, the mechanism of loperamide-induced cardiotoxicity is theorized to be due to dose-dependent effects on the voltage-gated L-type calcium channels, hERG/Ikr potassium channel and cardiac sodium channels, similar to the action of Vaughan-Williams class 1A, III, and IV anti-a ...
introduction - University of Twente
... descending coronary artery is embedded in the surface of the front side of the heart. The left circumflex coronary artery circles around the left side of the heart and is embedded in the surface of the back of the heart. Just like branches on a tree, the coronary arteries branch into progressively s ...
... descending coronary artery is embedded in the surface of the front side of the heart. The left circumflex coronary artery circles around the left side of the heart and is embedded in the surface of the back of the heart. Just like branches on a tree, the coronary arteries branch into progressively s ...
Uncontrolled ventricular rate in atrial fibrillation - Heart
... Atrial fibrillation is a rhythm in which the back to sinus rhythm. The recent development of a ventricular response is usually well controlled at rapid irregular pulse and progressively worsening the atrioventricular node level with digitalis or shortness of breath began one week before adpropranolo ...
... Atrial fibrillation is a rhythm in which the back to sinus rhythm. The recent development of a ventricular response is usually well controlled at rapid irregular pulse and progressively worsening the atrioventricular node level with digitalis or shortness of breath began one week before adpropranolo ...
Full Text - Life Science Journal
... cirrhosis therefore, it would be expected that this and other cardiac abnormalities would disappear after liver transplantation (LT). However, results from previous studies have been conflicting regarding this point (Torregrosa et al.,2005). Portal hypertension is an important and common complication ...
... cirrhosis therefore, it would be expected that this and other cardiac abnormalities would disappear after liver transplantation (LT). However, results from previous studies have been conflicting regarding this point (Torregrosa et al.,2005). Portal hypertension is an important and common complication ...
Nonlinear effects in subthreshold virtual electrode polarization
... mA less than the cathodal threshold, and the duration was 20–60 ms. The polarity of the stimuli was reversed each time to ensure a correct comparison between anodal and cathodal stimulations. Basic pacing stimulus strength was adjusted to twice the diastolic threshold of excitation. Numerical models ...
... mA less than the cathodal threshold, and the duration was 20–60 ms. The polarity of the stimuli was reversed each time to ensure a correct comparison between anodal and cathodal stimulations. Basic pacing stimulus strength was adjusted to twice the diastolic threshold of excitation. Numerical models ...
Nocturnal Overdrive Pacing for the Treatment of Sleep Apnea
... over a period of 30 minutes. Patients remained in each arm for 7 to 10 days. An in-hospital polysomnography (PSG) sleep study was conducted after at least 7 days in each therapy arm. The order of therapy was randomized. To establish baseline sleep schedules, patients maintained sleep diaries for the ...
... over a period of 30 minutes. Patients remained in each arm for 7 to 10 days. An in-hospital polysomnography (PSG) sleep study was conducted after at least 7 days in each therapy arm. The order of therapy was randomized. To establish baseline sleep schedules, patients maintained sleep diaries for the ...
A practical approach to torsade de pointes
... with the “noncardiac”drugs listed in Table I appears to depend on either high dosages or attainment of high plasma concentrations. The mechanisms underlying torsade de pointes occurring with terfenadine therapy have been the best studied,38 although cases during astemizole or cisapride therapy likel ...
... with the “noncardiac”drugs listed in Table I appears to depend on either high dosages or attainment of high plasma concentrations. The mechanisms underlying torsade de pointes occurring with terfenadine therapy have been the best studied,38 although cases during astemizole or cisapride therapy likel ...
Chapter 18 power point
... 1. There are two atrioventricular (AV) valves between each atrialventricular junction: the tricuspid valve in the right and the mitral valve in the left. a. When the heart is relaxed, the AV valves hang loosely down into the ventricles. b. When the ventricles contract, blood is forced upward against ...
... 1. There are two atrioventricular (AV) valves between each atrialventricular junction: the tricuspid valve in the right and the mitral valve in the left. a. When the heart is relaxed, the AV valves hang loosely down into the ventricles. b. When the ventricles contract, blood is forced upward against ...
Pericardial Effusions and Cardiac Tamponade
... Pulsed doppler – mitral valve inflow varies with respiration ...
... Pulsed doppler – mitral valve inflow varies with respiration ...
Right ventricle - Anatomy and Physiology
... • Heart Disease – Coronary Artery Disease • Angina pectoris • In its most common form, a temporary ischemia develops when the workload of the heart increases • Although the individual may feel comfortable at rest, exertion or emotional stress can produce a sensation of pressure, chest constriction, ...
... • Heart Disease – Coronary Artery Disease • Angina pectoris • In its most common form, a temporary ischemia develops when the workload of the heart increases • Although the individual may feel comfortable at rest, exertion or emotional stress can produce a sensation of pressure, chest constriction, ...
A Breijo Pattern Associated to a Wolff-Parkinson-White
... manner: In this clinical case, any epileptic focus was noted. ...
... manner: In this clinical case, any epileptic focus was noted. ...
Chronic vagus nerve stimulation improves left ventricular function in
... chronic VNS on cardiac remodeling and long-term survival in various animal model of chronic HF has been evaluated. In a rat myocardial infarction model [5], chronic VNS attenuated HF progression, prolonged survival time and improved the expression of biomarkers such as C-reactive protein (CRP). In b ...
... chronic VNS on cardiac remodeling and long-term survival in various animal model of chronic HF has been evaluated. In a rat myocardial infarction model [5], chronic VNS attenuated HF progression, prolonged survival time and improved the expression of biomarkers such as C-reactive protein (CRP). In b ...
Flip and See ECG
... appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibi ...
... appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibi ...
High-dose calcium channel-blocking therapy for
... patients fulfilled the diagnostic criteria for PPH based on history, physical examination, chest radiograph, lung scan, pulmonary function testing, two-dimensional echocardiography, and absence of either left-to-right shunting or elevated left heart pressures on catheterization, according to the pro ...
... patients fulfilled the diagnostic criteria for PPH based on history, physical examination, chest radiograph, lung scan, pulmonary function testing, two-dimensional echocardiography, and absence of either left-to-right shunting or elevated left heart pressures on catheterization, according to the pro ...
Print - Circulation Research
... Results were graded as follows: (o) isolated ventricular premature systoles; (6) frequent ventricular premature systoles, but not runs or bigeminal rhythm; (c) short runs of ventricular flutter or fibrillation, and (d) long runs of ventricular flutter or fibrillation. In the final interpretation, re ...
... Results were graded as follows: (o) isolated ventricular premature systoles; (6) frequent ventricular premature systoles, but not runs or bigeminal rhythm; (c) short runs of ventricular flutter or fibrillation, and (d) long runs of ventricular flutter or fibrillation. In the final interpretation, re ...
Measuring results that matter Heart Failure
... will open new possibilities to compare performance globally, allow clinicians to learn from each other, and rapidly improve the care we provide our patients. Our Standard Sets include baseline conditions and risk factors to enable meaningful case-mix adjustment globally, ensuring that comparisons of ...
... will open new possibilities to compare performance globally, allow clinicians to learn from each other, and rapidly improve the care we provide our patients. Our Standard Sets include baseline conditions and risk factors to enable meaningful case-mix adjustment globally, ensuring that comparisons of ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.