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Print - Circulation
Print - Circulation

... hormone or cortisone to patients suffering from acute rheumatic fever with carditis is often associated with dramatic clinical improvement; at times it appears to be life saving. The significance of this clinical response in terms of any true alteration of the long-term course of the illness cannot ...
Myocardial stress and hypertrophy - Journal of Clinical Investigation
Myocardial stress and hypertrophy - Journal of Clinical Investigation

... and was reactive to the activation of cardiomyocyte death pathways. A similar leukocyte infiltration was also observed in aortic stenosis patients with a reduced LVEF (13). Conclusions The 1975 study by Grossman et al. (1) continues to raise more questions than it answers. We still do not know the p ...
Chapter 29
Chapter 29

... responded with an AED that had dead batteries. The electrode pads must tightly adhere to the chest wall for optimal delivery of the electrical energy. Moisture prevents proper adhesion. A gauze 4-by-4 pad or a towel should be immediately available to wipe down the chest before applying the electrode ...
A comparison of the effects of strength and aerobic exercise training
A comparison of the effects of strength and aerobic exercise training

... considered positive for ischaemia. Heart rate, exercise time, maximum ST segment depression, estimated workload in metabolic equivalents, percentage of target heart rate reached are also recorded. A modified Balke protocol was used (Appendix B). This protocol was chosen because it was used in the pr ...
The epsilon waves clinical characterization and electrophysiological
The epsilon waves clinical characterization and electrophysiological

... U wave: Last, inconstant and smallest deflection of ECG that is recorded immediately after T wave and before the P of the following cycle, of equal polarity to the preceding T, i.e. positive where T also is. Voltage of U is always lower than 50% of the width of the preceding T and generally between ...
TRICUSPID ATRESIA
TRICUSPID ATRESIA

... VSD in tricuspid atresia • Associated VSD is common with TA, seen in about 90% of individuals during infancy. • Is usually perimembranous but also may occur in the muscular septum or as a component of an atrioventricular septal defect, although the latter is rare. • At birth the VSD is usually rest ...
Usefulness of Intra-aortic Balloon Pump Counterpulsation
Usefulness of Intra-aortic Balloon Pump Counterpulsation

... Strengths and limitations of this landmark trial have been discussed extensively. It is the largest randomized trial performed in patients with cardiogenic shock, including 600 patients in 32 months, and with a very high percentage of follow-up (1-year follow-up completed in 99.2%). Apart from that ...
Tei Index - Hellenic Journal of Cardiology
Tei Index - Hellenic Journal of Cardiology

... The superiority of the Tei index is attributed to its ability to reflect the combined systolic and diastolic performance (in contrast with the systolic ejection fraction), an advantage more evident in cases of isolated LV diastolic dysfunction. Furthermore, the index, as a Dopplerparameter, is indep ...
Left Ventricular Diastolic Dysfunction and Obesity: A Systematic
Left Ventricular Diastolic Dysfunction and Obesity: A Systematic

... setting of heart failure when loading parameters are usually disturbed , E' and E/E' ratio are the important measurement in TDI, and E/E' ratio can be used as an index of left ventricular filling pressures, also it is significantly correlated with mean pulmonary capillary wedge pressure (PCWP) [27]. ...
Cardiac Interpretation of Pediatric Chest X-Ray
Cardiac Interpretation of Pediatric Chest X-Ray

... This includes the volume within each cardiac chamber, cardiac wall thickness, pericardial space, and any other additional structure such as mass from a tumor or air trapped within the pericardium (pneumopericardium). Therefore, enlargement of any of these structures will lead to the appearance of ca ...
Transcatheter Pulmonary Valve Implantation - 1/16
Transcatheter Pulmonary Valve Implantation - 1/16

... Interventions for RVOT dysfunction often require repeat open heart surgery, resulting in numerous open heart procedures in patients who live into adulthood. Treatment options for pulmonary stenosis are open surgery with valve replacement, balloon dilatation, or percutaneous stenting. Interventions f ...
Participate in Work
Participate in Work

... What are the components of an AED? When is an AED used?  2. Irregular heart rhythms  a. Cardiac arrhythmia is the disturbance of a normal heart rhythm.  b. Ventricular fibrillation (V-Fib or VF) is an abnormal and potentially life threatening cardiac rhythm that occurs when no blood is pumped fr ...
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous

... The pressure within the structure that is perforated is a major determinant of the development and severity of tamponade. Thus a small perforation of the RV in an unanticoagulated patient may not be clinically apparent; in contrast, perforation of the RV in the setting of pulmonary hypertension or a ...
WQRS-internist
WQRS-internist

... Treatment when in doubt Stable or unstable-Electricity If possible, get 12-lead ECG first If electricity does not work ...
Diagnosis and Treatment of Sick Sinus Syndrome -
Diagnosis and Treatment of Sick Sinus Syndrome -

... ick sinus syndrome is a generalized abnormality of cardiac impulse formation that may be caused by an intrinsic disease of the sinus node that makes it unable to perform its pacemaking function, or by extrinsic causes.1 Abnormalities encompassed in this syndrome include sinus bradycardia, sinus arre ...
Stenting To Reverse Left Ventricular Ischemia Due To Left Main
Stenting To Reverse Left Ventricular Ischemia Due To Left Main

... heart disease has infrequently been described previously.6 – 8 The left main coronary artery has a characteristic angiographic appearance, with severe narrowing at the ostium and then gradual enlargement to the distal left main artery with normal appearance of the remainder of the coronary circulati ...
Lipomatous Hypertrophy of the Interatrial Septum
Lipomatous Hypertrophy of the Interatrial Septum

... Normally, the atrial septum is less than 1.0 cm thick. The lipomatous hypertrophy may produce bulging of the interatrial septum and that measures 1.0 to 5.0 cm (average 2.6 cm) in thickness.1-3 This entity was first described at a postmortem examination in 1964 by Prior.4 The incidence is very rare ...
Global Cardiovascular Reserve Dysfunction in Heart
Global Cardiovascular Reserve Dysfunction in Heart

... Conclusions ...
Heart Lung Transplant
Heart Lung Transplant

... transplantation provides a survival benefit in appropriately selected patients. It may be the only option for some patients with end-stage cardiopulmonary disease. Heart/lung transplant is contraindicated in patients in whom the procedure is expected to be futile due to comorbid disease or in whom p ...
What is Sudden Death in Athletes
What is Sudden Death in Athletes

... struck in the chest while batting by a pitched ball thrown at approximately 40 mph from a distance of 40 feet or farther. Catastrophes similar to this have occurred in a variety of sports (baseball, ice hockey, softball, ...
Palpitations
Palpitations

... Sometimes, arrhythmias cause no symptoms and can only be detected by feeling the pulse or doing an electrocardiogram (ECG) recording. This is a test that gives information about the rhythm and electrical activity of the heart. Almost all patients who have symptoms associated with their palpitations ...
Sleep-Disordered Breathing and Cardiovascular
Sleep-Disordered Breathing and Cardiovascular

... many of the trial participants. Post-hoc analyses revealed significantly better transplant-free survival (hazard ratio 0.371, P ⫽ .043) in subjects whose AHI had been reduced to less than 15 events/h, compared to control subjects. Whether advanced methods of applying PAP in heart-failure patients wi ...
High diagnostic accuracy of NT-proBNP for cardiac origin of pleural effusions
High diagnostic accuracy of NT-proBNP for cardiac origin of pleural effusions

... from all patients presenting at the Dept of Pulmonology of Dresden University Hospital, a tertiary care referral centre for diagnostic or therapeutic thoracentesis, between April 2004 and May 2005. In patients presenting repeatedly for thoracentesis, only the first episode was included. Pleural flui ...
European Association of Cardiovascular Imaging
European Association of Cardiovascular Imaging

... algorithm for the left atrium) or 3DE. Tricuspid regurgitation should be looked for and properly assessed in all echocardiographic studies. In case of significant changes in severity of tricuspid regurgitation during follow-up, a 2D/3D and colour Doppler assessment of its severity and mechanisms sho ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... dysfunction and diastolic dysfunction in this population. It often reveals increased left ventricular mass with low-normal or increased wall thickness and dilated left ventricle. Dilated cardiomyopathy is strongly associated with a low CD4 cell count. Clinical and echocardiographic findings suggeste ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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