Sudden cardiac death in chronic kidney disease: epidemiology and prevention
... with the subsequent development of heart failure. 19 Progressive hypertrophy is partly explained by hypertension, but not by a wide array of potential risk factors, including moderate anemia.20 lvH could predispose individuals to sudden death through prolongation of corrected Qt (Qtc) interval or by ...
... with the subsequent development of heart failure. 19 Progressive hypertrophy is partly explained by hypertension, but not by a wide array of potential risk factors, including moderate anemia.20 lvH could predispose individuals to sudden death through prolongation of corrected Qt (Qtc) interval or by ...
Surgical Repair of Posterior Mitral Valve Prolapse
... including a leaflet procedure (resection, with or without sliding repair) and annular procedure (prosthetic annuloplasty), can be performed without advanced techniques. Data from the Society of Thoracic Surgeons (STS) Database suggest that that only a small proportion of patients with degenerative m ...
... including a leaflet procedure (resection, with or without sliding repair) and annular procedure (prosthetic annuloplasty), can be performed without advanced techniques. Data from the Society of Thoracic Surgeons (STS) Database suggest that that only a small proportion of patients with degenerative m ...
Iatrogenic Pericardial Effusion and Tamponade in the Percutaneous
... The pressure within the structure that is perforated is a major determinant of the development and severity of tamponade. Thus a small perforation of the RV in an unanticoagulated patient may not be clinically apparent; in contrast, perforation of the RV in the setting of pulmonary hypertension or a ...
... The pressure within the structure that is perforated is a major determinant of the development and severity of tamponade. Thus a small perforation of the RV in an unanticoagulated patient may not be clinically apparent; in contrast, perforation of the RV in the setting of pulmonary hypertension or a ...
macrowave t alternans or macroscopic alternation in a
... Isolated T wave alternans (phase 3 of AP) in absence of QRS complex changes (phase 0 of AP) or of P wave, was described for the first time by Hering in 1908 and 19091;2 and by Lewis in 19103. In 1913 Mines described it as the consequence of electrolytic alterations4 and Taussig in the papillary musc ...
... Isolated T wave alternans (phase 3 of AP) in absence of QRS complex changes (phase 0 of AP) or of P wave, was described for the first time by Hering in 1908 and 19091;2 and by Lewis in 19103. In 1913 Mines described it as the consequence of electrolytic alterations4 and Taussig in the papillary musc ...
Impaired left ventricular relaxation in type 2 diabetic rats is related to
... LV dysfunction in rats with type 2 diabetes mellitus. More specifically, we have shown that myocardial relaxation is prolonged when LV contractility and compliance are not (yet) significantly impaired in diabetic rats at age 37 weeks. The functional impairment is related to the myocardial accumulati ...
... LV dysfunction in rats with type 2 diabetes mellitus. More specifically, we have shown that myocardial relaxation is prolonged when LV contractility and compliance are not (yet) significantly impaired in diabetic rats at age 37 weeks. The functional impairment is related to the myocardial accumulati ...
Recurrent aborted sudden cardiac death with seizures and
... The most likely cause of the seizures was cerebral hypoxia during ventricular fibrillation. A third point of interest concerning this case is the question if the patient suffered from a hereditary disease and if bulimia was a manifestation of this presumed genetic defect. Some of the clinical manife ...
... The most likely cause of the seizures was cerebral hypoxia during ventricular fibrillation. A third point of interest concerning this case is the question if the patient suffered from a hereditary disease and if bulimia was a manifestation of this presumed genetic defect. Some of the clinical manife ...
The emerging role of cardiovascular magnetic resonance imaging
... (81). Ventricular dysfunction and structural changes have been documented by both echocardiography and cardiovascular magnetic resonance imaging (82,83). However, the prevalence of heart failure is approximately 2% to 7% (83,84). Sudden death is not unusual in DM1, and was initially believed to be d ...
... (81). Ventricular dysfunction and structural changes have been documented by both echocardiography and cardiovascular magnetic resonance imaging (82,83). However, the prevalence of heart failure is approximately 2% to 7% (83,84). Sudden death is not unusual in DM1, and was initially believed to be d ...
Role of atrioventricular nodal ablation and pacemaker therapy in
... CRT may be considered for patients with LV ejection fraction ≤35% with NYHA functional class I or II symptoms who are receiving optimal recommended medical therapy and who are undergoing implantation of a permanent pacemaker and/or ICD with anticipated frequent ventricular pacing [33] . Heart fai ...
... CRT may be considered for patients with LV ejection fraction ≤35% with NYHA functional class I or II symptoms who are receiving optimal recommended medical therapy and who are undergoing implantation of a permanent pacemaker and/or ICD with anticipated frequent ventricular pacing [33] . Heart fai ...
Sox4-Deficiency Syndrome in Mice Is an Animal Model for Common
... 3-dimensionally reconstructed serial sections between ED12 and ED14. Although Sox4 is expressed in the endocardially derived tissue of both the outflow tract and atrioventricular canal, Sox4-deficient hearts only suffer from defective transformation of the endocardial ridges into semilunar valves an ...
... 3-dimensionally reconstructed serial sections between ED12 and ED14. Although Sox4 is expressed in the endocardially derived tissue of both the outflow tract and atrioventricular canal, Sox4-deficient hearts only suffer from defective transformation of the endocardial ridges into semilunar valves an ...
Effect of Aldosterone Antagonism on Exercise - MET-TEST
... velocity (E/e 0 ) was determined to approximate LVFP. On the basis of previous validation, exertional septal E/e 0 >13 was considered as a marker of exerciseinduced elevation of LV filling pressure (25). ...
... velocity (E/e 0 ) was determined to approximate LVFP. On the basis of previous validation, exertional septal E/e 0 >13 was considered as a marker of exerciseinduced elevation of LV filling pressure (25). ...
Serotonin, and probably not Angiotensin II, mediates cyclic strain
... Disatian et al13 showed there are more fibroblast phenotype VICs in normal mitral valves and the phenotype of interstitial cells with progressive DMVD showed markedly higher myofibroblast phenotype. Komuro14 also proposed that a family of fibroblast-like cells exist which varies its phenotype as an ...
... Disatian et al13 showed there are more fibroblast phenotype VICs in normal mitral valves and the phenotype of interstitial cells with progressive DMVD showed markedly higher myofibroblast phenotype. Komuro14 also proposed that a family of fibroblast-like cells exist which varies its phenotype as an ...
Mitral Valve Repair
... failure.18.20At this time, anterior leaflet prolapse should be corrected by chordal transfer or the creation of an artifical chordae.20J2Failure to perform a ring annuloplasty increases the risk of repair failure.'l Therefore, nearly all mitral valve repairs in adults should be accompanied by a ring ...
... failure.18.20At this time, anterior leaflet prolapse should be corrected by chordal transfer or the creation of an artifical chordae.20J2Failure to perform a ring annuloplasty increases the risk of repair failure.'l Therefore, nearly all mitral valve repairs in adults should be accompanied by a ring ...
Valvular-ventricular interaction: importance of the
... this hypothesis, 10 dogs anesthetized with fentanyl were studied during cardiopulmonary bypass. The importance of the mitral apparatus in left ventricular systolic function was assessed independent of load by means of the slope of the contractile state-dependent left ventricular peak isovolumetric p ...
... this hypothesis, 10 dogs anesthetized with fentanyl were studied during cardiopulmonary bypass. The importance of the mitral apparatus in left ventricular systolic function was assessed independent of load by means of the slope of the contractile state-dependent left ventricular peak isovolumetric p ...
269 the intrinsic properties of an in situ perfused crocodile heart
... arch has been retained, the left in mammals and the right in birds, both systemic arches are present in the crocodilians. The right systemic arch arises from the left ventricle and the left systemic arch and the pulmonary arterial trunk arise as separate distinct vessels from the right ventricle. Mo ...
... arch has been retained, the left in mammals and the right in birds, both systemic arches are present in the crocodilians. The right systemic arch arises from the left ventricle and the left systemic arch and the pulmonary arterial trunk arise as separate distinct vessels from the right ventricle. Mo ...
Myocardial Recovery and the Failing Heart
... with an improvement in the clinical manifestations and outcomes in heart failure, raising the interesting possibility that reverse remodeling is linked mechanistically to the observed improved heart failure outcomes. Although the precise cellular and molecular mechanisms that are responsible for the ...
... with an improvement in the clinical manifestations and outcomes in heart failure, raising the interesting possibility that reverse remodeling is linked mechanistically to the observed improved heart failure outcomes. Although the precise cellular and molecular mechanisms that are responsible for the ...
Right Ventricular Remodeling and Dysfunction With Subsequent
... tethering force and restricts leaflet closure.15 When considering these findings, isolated TR might be viewed as functional regurgitation associated with dilated cardiomyopathy, exclusively involving the RV. Because dilated cardiomyopathy is characterized by cardiac enlargement and impaired systolic ...
... tethering force and restricts leaflet closure.15 When considering these findings, isolated TR might be viewed as functional regurgitation associated with dilated cardiomyopathy, exclusively involving the RV. Because dilated cardiomyopathy is characterized by cardiac enlargement and impaired systolic ...
Ratio of Peak Early to Late Diastolic Filling Velocity of the Left
... as an important clinical entity, since it is the most common cause of death in patients with acute ischemic stroke.1−3）Transesophageal echocardiography（TEE）has been established as an essential investigation for detecting thromboembolic sources and determining stroke subtypes.4−12）Since TEE is a semi ...
... as an important clinical entity, since it is the most common cause of death in patients with acute ischemic stroke.1−3）Transesophageal echocardiography（TEE）has been established as an essential investigation for detecting thromboembolic sources and determining stroke subtypes.4−12）Since TEE is a semi ...
51st Annual Meeting of the Association for European
... The Conference Organisers have taken all reasonable care in making arrangements for the Conference. In the event of unforeseen disruptions, neither AEPC nor their agents can be held responsible for any losses or damages incurred by delegates. The programme is correct at the time of printing, but org ...
... The Conference Organisers have taken all reasonable care in making arrangements for the Conference. In the event of unforeseen disruptions, neither AEPC nor their agents can be held responsible for any losses or damages incurred by delegates. The programme is correct at the time of printing, but org ...
Mitral Valve Regurgitation: Surgical Treatment
... Although many surgeons do not recommend the use of an annuloplasty ring after mitral reconstruction, most of them believe that a ring strengthens the repair results and reduces regurgitation postoperatively. Of course, the implantation of a prosthetic ring is not without complications: partial abrup ...
... Although many surgeons do not recommend the use of an annuloplasty ring after mitral reconstruction, most of them believe that a ring strengthens the repair results and reduces regurgitation postoperatively. Of course, the implantation of a prosthetic ring is not without complications: partial abrup ...
THE ROLE OF AUTONOMIC AND MYOCARDIAL FACTORS I.N
... performed. A no. 9 bird's-eye catheter was inserted from the external jugular vein into the main pulmonary artery for injections of contrast material, and a no. 7 plain catheter was passed through the carotid artery into the left ventricle for pressure recordings. The animal was then suspended horiz ...
... performed. A no. 9 bird's-eye catheter was inserted from the external jugular vein into the main pulmonary artery for injections of contrast material, and a no. 7 plain catheter was passed through the carotid artery into the left ventricle for pressure recordings. The animal was then suspended horiz ...
Stenting To Reverse Left Ventricular Ischemia Due To Left Main
... heart disease has infrequently been described previously.6 – 8 The left main coronary artery has a characteristic angiographic appearance, with severe narrowing at the ostium and then gradual enlargement to the distal left main artery with normal appearance of the remainder of the coronary circulati ...
... heart disease has infrequently been described previously.6 – 8 The left main coronary artery has a characteristic angiographic appearance, with severe narrowing at the ostium and then gradual enlargement to the distal left main artery with normal appearance of the remainder of the coronary circulati ...
Late ventricular geometry and performance changes of
... volume-loaded stage are noted 6 to 9 months after the hemiFontan pmcedure; however,major changesoccur 1 to 2 yearsafter the Footan procedure. The dramatic cbaoges in the mass/volume ratio seenearly after the hemiFontan procedure were not detected at 6 to 9 months. Furthermore, diminution of mass, vo ...
... volume-loaded stage are noted 6 to 9 months after the hemiFontan pmcedure; however,major changesoccur 1 to 2 yearsafter the Footan procedure. The dramatic cbaoges in the mass/volume ratio seenearly after the hemiFontan procedure were not detected at 6 to 9 months. Furthermore, diminution of mass, vo ...
THE ROLE OF AUTONOMIC AND MYOCARDIAL FACTORS I.N
... performed. A no. 9 bird's-eye catheter was inserted from the external jugular vein into the main pulmonary artery for injections of contrast material, and a no. 7 plain catheter was passed through the carotid artery into the left ventricle for pressure recordings. The animal was then suspended horiz ...
... performed. A no. 9 bird's-eye catheter was inserted from the external jugular vein into the main pulmonary artery for injections of contrast material, and a no. 7 plain catheter was passed through the carotid artery into the left ventricle for pressure recordings. The animal was then suspended horiz ...
Cardiac Surgery: Aortic Aneurysms
... called an aortic dissection (see Figure 3). The inner tear causes bleeding into the other layers of the vessel. As the bleeding increases, the layers of tissue separate and weaken the aortic wall. This can lead to an aneurysm which can rupture. The tear can start anywhere along the aorta from the be ...
... called an aortic dissection (see Figure 3). The inner tear causes bleeding into the other layers of the vessel. As the bleeding increases, the layers of tissue separate and weaken the aortic wall. This can lead to an aneurysm which can rupture. The tear can start anywhere along the aorta from the be ...
Right Ventricular Ejection Function Assessed by - J
... consecutive subjects (34 males/10 females) were enrolled: 16 had normal hemodynamic parameters without significant coronary artery stenosis, 15 had hypertrophic cardiomyopathy and 13 had dilated cardiomyopathy. Biplane right ventricular cineangiography was performed and the percent shortening of the ...
... consecutive subjects (34 males/10 females) were enrolled: 16 had normal hemodynamic parameters without significant coronary artery stenosis, 15 had hypertrophic cardiomyopathy and 13 had dilated cardiomyopathy. Biplane right ventricular cineangiography was performed and the percent shortening of the ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.