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Echo-Doppler assessment of diastole: flow, function and
Echo-Doppler assessment of diastole: flow, function and

... developed by muscle physiologists and by cardiologists with a strong background in physics (cardiac mechanics and fluid dynamics). These scientists described left ventricular (LV) material properties in terms of pressures and volumes, and their mutual relation. When a given volume is added to a ventr ...
Tricuspid regurgitation in a child after closure of a
Tricuspid regurgitation in a child after closure of a

... valve becomes relatively stenotic and a diastolic murmur is established. When the vascular resistance is elevated and thereby the pulmonary arterial pressure is high, the capacity for vasodilation is lost and the pulmonary flow decreases. Consequently, the pulmonary venous return is less. The presen ...
valves - Anatomy and Physiology
valves - Anatomy and Physiology

... • Anterior interventricular sulcus – Anterior position of interventricular septum ...
Consensus Paper on Out-of-Hospital Cardiac Arrest in England
Consensus Paper on Out-of-Hospital Cardiac Arrest in England

... promptly and effectively is therefore crucial, at least until a defibrillator arrives (and often also immediately following defibrillation), if the person is to survive. This is true even in the case of in-hospital cardiac arrests where defibrillators are more often readily available. It should be n ...
Consensus Paper on Out-of-Hospital Cardiac Arrest in England Date: 16
Consensus Paper on Out-of-Hospital Cardiac Arrest in England Date: 16

... promptly and effectively is therefore crucial, at least until a defibrillator arrives (and often also immediately following defibrillation), if the person is to survive. This is true even in the case of in-hospital cardiac arrests where defibrillators are more often readily available. It should be n ...
09_discussion
09_discussion

... a 57 years old male, which revealed only subendocardial infarct, the period of survival in this case was not known. The query whether the subendocardial infarct might have progressed to a transmural infarct given a sufficient survival period can perhaps never be answered. Considering the transmural ...
Role of percutaneous left ventricular assist devices in preventing
Role of percutaneous left ventricular assist devices in preventing

... myocardial infarction resuscitated from cardiac arrest. CPR 3 years: 3‑year survival without neurological sequelae for cardiac arrest patients treated with conventional CPR. CCR 3 years: 3‑year survival without neurological sequelae for cardiac arrest patients treated with CCR (includes urgent hypot ...
Congestive heart failure in the dog
Congestive heart failure in the dog

... and medium-size breeds of dogs are predisposed to chronic valvular disease. CHF is more usual in middle-aged to older dogs, but can develop as a result of congenital disease; dilated cardiomyopathy can be seen within the first few years of life. In general, there is a slight predisposition for the d ...
The surgeon`s role in transcatheter aortic valve implantation (TAVI)
The surgeon`s role in transcatheter aortic valve implantation (TAVI)

... apex and the aortic valve, which might allow for a more precise implantation and there is no limitation in sheath diameter. The avoidance of the retrograde crossing of the aortic arch is another great advantage of TA-AVI and it might be reflected by the trend towards lower stroke rates with TA.(27-2 ...
Stress–strain behavior of mitral valve leaflets in
Stress–strain behavior of mitral valve leaflets in

... stiffness ranging from 0.06 to 0.09 N/mm2 and post-transitional stiffness from 2 to 9 N/mm2. We used inverse finite element (FE) analysis to test, for the first time, whether the anterior mitral leaflet (AML), in vivo, exhibits similar non-linear behavior during isovolumic relaxation (IVR). Miniature r ...
Print - Circulation
Print - Circulation

... Successful electroversion is not related to age or sex, type of heart disease (lone atrial fibrillation accepted), overall body size, nor to the size of the f waves in lead V1 of the electrocardiogram,18 but does depend on the duration of the rhythm disturbance, being less than 50% when atrial fibri ...
Diastolic Heart Failure - Texas Tech University Health Sciences Center
Diastolic Heart Failure - Texas Tech University Health Sciences Center

... include Doppler assessment of flow into the left atrium through the pulmonary veins, and tissue Doppler imaging, which allows for direct measurement of the velocity of change in myocardial length, an index of left ventricular relaxation. The latter technique, in particular, is less sensitive to prel ...
Diastolic Heart Failure - Ether
Diastolic Heart Failure - Ether

... include Doppler assessment of flow into the left atrium through the pulmonary veins, and tissue Doppler imaging, which allows for direct measurement of the velocity of change in myocardial length, an index of left ventricular relaxation. The latter technique, in particular, is less sensitive to prel ...
Clinical approach to determination of the need for prophylaxis in
Clinical approach to determination of the need for prophylaxis in

... prophylaxis should consider the following: – the degree to which the patient’s underlying condition creates a risk of endocarditis – the apparent risk of bacteremia with the procedure – the potential adverse reactions of the prophylactic antimicrobial agent to be used; and the cost-benefit aspects o ...
Distribution of normal human left ventricular myofiber stress at end
Distribution of normal human left ventricular myofiber stress at end

... end diastole and end systole: a target for in silico design of heart failure treatments. J Appl Physiol 117: 142–152, 2014. First published May 29, 2014; doi:10.1152/japplphysiol.00255.2014.—Ventricular wall stress is believed to be responsible for many physical mechanisms taking place in the human ...
Impact of Longitudinal Myocardial Deformation on the Prognosis of
Impact of Longitudinal Myocardial Deformation on the Prognosis of

... of strain over strain rate may also be related to a les allowing an easier e assessment of peak value. The use of longitudinal global strain er straa by speckle tracking in assessing LV contractility should be encouraged in clinical practicee for its good s sing reproducibility and ability to strati ...
Increased cardiac work provides a link between systemic
Increased cardiac work provides a link between systemic

... fraction, end diastolic volume (EDV), end systolic volume (ESV), and stroke volume. Longitudinal and radial (both anterior-posterior and septal-lateral) fractional shortening were also calculated from the 3D models using customized software. In addition to the aforementioned indices, stroke work was ...
ecG in non cardiac Disorders - The Association of Physicians of India
ecG in non cardiac Disorders - The Association of Physicians of India

... temperature is less than 35°C. The earliest change seen in the electrocardiogram is an artifact due to shivering, although some hypothermic patients have relatively normal ECG. As body temperature falls further, all metabolic and cardiovascular processes slow progressively. This results in bradycard ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Of total 155 patients, Complete Heart Block (CHB) was found to be the commonest indication (in 94 cases, 60.6%) for permanent pacemaker implantation followed by Sick Sinus Syndrome (SSS) in 20 cases (12.9%). In the USA, sinus-node dysfunction is the primary indication for pacemaker implantation in o ...
Dispersion of QT interval in patients with and without
Dispersion of QT interval in patients with and without

... extrastimuli and two basic drive cycle lengths (600 and 400 ms) from the right ventricular apex and outflow tract. Ventricular tachycardia was defined as 1) sustained when its duration was >30 s or if defibrillation was required for its termination; and 2) as nonsustained if it lasted >5 beats but < ...
abnormal curves in terms of the pathological conditions with which
abnormal curves in terms of the pathological conditions with which

... in each heart beat during normal complete respiratory cycles, and the results averaged. Mean pressures were determined by planimetric integration. The data from arterial pressure records include average maximum (systolic), average minimum (diastolic), and mean pressures. For the auricle, only mean p ...
WQRS-internist
WQRS-internist

... QTU interval in the sinus beats is at least 600 milliseconds. Note TU wave alternans in the first and second complexes. A late premature complex occurring in the downslope of the TU wave initiates an episode of ventricular tachycardia ...
the PDF file
the PDF file

... properties governing Frank Sterling‟s law of the heart, ESC was elicited in which the hypothesis was that the contractions would vary depending on the time available for ventricular filling and time of stimulation.(Hoffman et al, 1965). Other properties also explored in this lab include the frog hea ...
009//  Aortic Stenosis CONTENTS
009// Aortic Stenosis CONTENTS

... The baseline is shifted upward and the velocity range adapted (8 m/s). Additionally, the LVOT velocity can be seen within the AS spectrum, indicating good ...
Cardiology - 12DaysinMarch
Cardiology - 12DaysinMarch

... 2. For the right heart to fill more (during inspiration), the left heart must fill less. 3. Since the free wall of the RV cannot distend (into the pericardial space), the interventricular septum must bulge into the left chamber. ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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