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Increase of QRS Duration as a Predictor of Impending Ventricular
Increase of QRS Duration as a Predictor of Impending Ventricular

... less-pronounced increase around minute 20 after the onset of occlusion. This two-peaked pattern is in agreement with the two phases of arrhythmia-incidence in a canine myocardial infarction model, previously reported in [14]. The first phase, named Ia phase, occurs from 2 to 10 minutes after the ons ...
Cardiogenic Shock - The Association of Physicians of India
Cardiogenic Shock - The Association of Physicians of India

... Diuretics should be used to treat pulmonary congestion and enhance oxygenation.Frusemide is drug of choice used in doses of 20-80 mg intravenous boluses.The frequency of administration should be decided by pulmonary congestive states preferably guided by PCWP measurements, to be maintained below 25 ...
Volume and Oxygen Consumption in Man
Volume and Oxygen Consumption in Man

... and 2. When data from all 20 patients were analyzed there was no significant change in end-diastolic volume, while both the endsystolic fraction and end-systolic volume decreased significantly (p < 0.001 and p < 0.025, respectively). Because prior studies in dogs' had indicated a high individual var ...
1 - American College of Radiology
1 - American College of Radiology

... The average diameter of these two measurements is used as the reference normal diameter of the vessel. The diameter of the abnormal segment is divided by the reference normal diameter to arrive at a percentage of stenosis or dilatation (% stenosis or dilation = abnormal segment [mm] referenced to th ...
Regional Tissue Oximetry Reflects Changes in Arterial Flow in
Regional Tissue Oximetry Reflects Changes in Arterial Flow in

... started with pacing rate of 200 beats/min. Subsequently, the frequency was escalated and titrated between 200 and 240 beats/min with respect to the heart failure progression (Moe et al. 1988, Chow et al. 1990, Hendrick et al. 1990, Tomita et al. 1991). Veterinary surveillance and clinical check-ups ...
Congenitally Corrected Transposition of the Great Arteries
Congenitally Corrected Transposition of the Great Arteries

... The natural history of ccTGA depends largely on the presence of associated defects. Patients under 5 years old who also have VSD, LVOTO, and/or TV abnormalities represent the highest frequency of non-surgical deaths. However patients with isolated ccTGA (no associated lesions) may survive into their ...
Right Ventricular Assessment in Adult Congenital Heart Disease
Right Ventricular Assessment in Adult Congenital Heart Disease

... Background: There is little data on right ventricular (RV) remodeling patterns in complex congenital heart disease (CHD) patients with right ventricle to pulmonary artery (PA) conduits, and novel RV imaging modalities have not been explored in this population. Knowledge of the RV remodeling process ...
Zaporozhye State Medical University
Zaporozhye State Medical University

... Pacemaker artifact (blip or spike) - the ECG waveform produced by a mechanical pacemaker impulse. It can be either an upward or a downward deflection depending on how the pacing wires are connected to the pulse generator. Parasympathetic nervous system - portion of autonomic system that acts to main ...
2 Cardiogenic Shock Simon G.Williams, ,
2 Cardiogenic Shock Simon G.Williams, ,

... Objectives of Hemodynamic Evaluation The primary objectives of hemodynamic evaluation in cardiogenic shock are to guide the treatment of this precarious condition (29) and to provide prognostic information (26,27). One of the earliest attempts to use hemodynamic evaluation to determine prognosis and ...
Response of recurrent sustained ventricular tachycardia to verapamil
Response of recurrent sustained ventricular tachycardia to verapamil

... A 28-year-old nman was admitted to hospital in March 1979 because of a recurrent attack of sustained ventricular tachycardia. He had experienced the first attack at the age of 18 and six additional attacks had occurred between October 1977 and the time of admission, for which he had been treated in ...
Positive jugular pulse
Positive jugular pulse

... always produce a pulse wave because of inadequate strength. The detection of a pulse deficit enables extrasystolic arrhythmia to be differentiated from heart block. During respiration the pulse rate in some species (particularly dogs) is appreciably more frequent during inspiration than during expir ...
A case of Tetralogy of Fallot with left coronary artery to pulmonary
A case of Tetralogy of Fallot with left coronary artery to pulmonary

... with right ventricular type of apex, concave pulmonary bay and a prominent aortic knuckle. Electrocardiogram revealed sinus rhythm with features of right ventricular hypertrophy and right axis deviation. The transthoracic echocardiography showed large sub aortic ventricular septal defect with 60 % a ...
Elevated circulating cardiotrophin-1 in heart failure
Elevated circulating cardiotrophin-1 in heart failure

... myocyte length secondary to an increase in the numbers of sarcomeres in series [12,20]. The degree of side-to-side slippage of myocytes does not correlate with the magnitude of ventricular enlargement ; furthermore, myocyte lengthening alone may account for all the ventricular dilatation seen in car ...
Safe Right Bundle Branch Block Pattern During Permanent Right
Safe Right Bundle Branch Block Pattern During Permanent Right

... portions of the interventricular septum which are anatomically right ventricle may behave functionally and electrically as left ventricle (10). Barold et al. (11) suggested that the RBBB pattern could be the result of a combination of RV activation delay due to severe disease of the RV conduction sy ...
Full-Text PDF
Full-Text PDF

... a Valsalva manoeuvre during individual efforts. This respiratory manoeuver equalizes transmural pressures and so the wall stress, or afterload, faced by the left ventricle (LV), is not significantly greater than at rest [22]. Thus, if athletes do perform a Valsalva during resistance activities, the ...
Imaging cardiac activation sequence during ventricular tachycardia
Imaging cardiac activation sequence during ventricular tachycardia

... was exposed via median sternotomy, and up to 47 transmural plunge-needle electrodes were inserted in the LV and right ventricle (RV). Each LV plunge-needle electrode contains four bipolar electrode-pairs (inter-electrode distance of 500 ␮m), each separated by 2.5 mm (28, 29), and each RV electrode c ...
Paroxysmal Supraventricular Tachycardia in Patients
Paroxysmal Supraventricular Tachycardia in Patients

... of the Wolff-Parkinson-White syndrome should not be taken as evidence that such an event could not occur. Three months prior to study, case 7, who only demonstrated evidence of pre-excitation with coronary sinus pacing, had an episode of ventricular flutter-fibrillation induced by a bout of atrial f ...
Effect of Sublingual Nitroglycerin on Regional Flow in
Effect of Sublingual Nitroglycerin on Regional Flow in

... heart rate in the patient groups studied. This approach resulted in a similar systolic arterial pressure-heart rate product and left ventricular end-diastolic pressure reduction in these patients. Alterations in coronary blood flow and resistance patterns, however, were strikingly different. In pati ...
Amiodarone-Induced Third Degree Atrioventricular Block and
Amiodarone-Induced Third Degree Atrioventricular Block and

... and non-significant stenosis of the epicardial coronary arteries ruling out ischemic heart disease. Amiodarone is the most potent antiarrhythmic agent in the prevention of lethal ventricular arrhythmias and demonstrates a very low incidence of torsade de pointes. Several randomized, controlled, clin ...
Circulation: Heart Failure Topic Review
Circulation: Heart Failure Topic Review

... dilated cardiomyopathy within 6 weeks. Moreover, increased load by dynamic exercise or aortic constriction accelerated progression into heart failure without a prior phase of adaptive hypertrophy. This strengthens the perception that appropriate growth responses with intact signaling via the insulin ...
Diastolic Heart Failure: A Concise Review
Diastolic Heart Failure: A Concise Review

... patients with typical symptoms of congestive heart failure, have a normal or slightly reduced ejection fraction. In these patients, diastolic dysfunction is implicated as a major contributor, if not the primary cause of congestive heart failure [1, 2]. The syndrome of clinical heart failure with nor ...
MI in KAWASAKI`S DISEASE
MI in KAWASAKI`S DISEASE

... Exercise - Bodily exertion for the purpose of restoring the the and functions to a healthy state or keeping them healthy 1.Dynamic:changes in muscle length and joint movement with small force. 2.Static: large force with little or no change in muscle length or joint move. E.J.Lovett, Jr. MD WRAMC ...
FREE Sample Here
FREE Sample Here

... 49. Blood travels from the body to the right side of the heart to the pulmonary circulation and then returns to the left side of the heart prior to being pumped to the coronary circulation and systemic circulation. True False ...
Evaluation of Known or Suspected Cardiac Sarcoidosis
Evaluation of Known or Suspected Cardiac Sarcoidosis

... in the United States and Europe with a 3-fold higher risk in blacks than in whites.2 Cardiac sarcoidosis (CS), which affects at least one quarter of patients,3 portends a worse prognosis and accounts for substantial mortality and morbidity from this disease. Although CS is often under diagnosed, inc ...
B-Type Natriuretic Peptide: A Novel Clinical Tool for
B-Type Natriuretic Peptide: A Novel Clinical Tool for

... Physical examination, including jugular venous distention, pulmonary rales, abdominal jugular reflux, and peripheral edema suggest fluid overload but are not sensitive or specific signs.7–9 The best clinical predictors of heart failure are increased heart size on chest radiograph (81% accuracy), his ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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