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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... of blood. These openings are guarded by valves for the purpose of scheduled and controlled flow of blood. The periphery to which the valves are attached is termed as the annulus. Atrioventricular valves are two in number namely tricuspid and mitral (bicuspid), named based on the number of cusps and ...
conduction-sinus-atrial
conduction-sinus-atrial

... atrium and elevate atrial pressures - mitral valve disease - hyperthyroidism - primary myocardial disease - pericardial disease ...
Asymptomatic Patient Screening
Asymptomatic Patient Screening

... MCG for Early Detection of Heart Disease Are there any individuals who should not take an MCG exam? Individuals who are not able to lie down cannot take an MCG exam. Pacemakers create electrical signals that interfere with the MCG measurement; therefore, patients with pacemakers are not advised to ...
Percutaneous Closure of Left Ventricular Pseudoaneurysm
Percutaneous Closure of Left Ventricular Pseudoaneurysm

... by the pericardium. In many cases, cardiac rupture results in cardiac tamponade and death.1 In left ventricular pseudoaneurysm, however, this rupture is contained by pericardial adhesions or a new thrombus, preventing exsanguination.1– 6 The true incidence of left ventricular pseudoaneurysms is unkn ...
papaver
papaver

... feedback at an early phase to evaluate the functionality. Furthermore, they allow our clinical partners to conduct research with cutting edge image analysis methods. The results of this applied clinical research will be published allowing the establishment of a new standard in the image analysis TAV ...
Evaluation Pulmonary Arterial End-Diastolic Pressure
Evaluation Pulmonary Arterial End-Diastolic Pressure

... in 24 patients with normal left ventricular function and in 26 patients with left ventricular myocardial disease and elevated EDP (range 13 to 38 mm Hg; average 22 mm Hg). In patients with normal left ventricular function, the EDPs in the left ventricle and pulmonary artery were equal (range 5 to 12 ...
Methods for Measuring Right Ventricular Function
Methods for Measuring Right Ventricular Function

... The RV is a crescent-shaped chamber that wraps around the LV. The complex shape makes estimation of volumes and surface areas challenging. The RV free wall is thinner than the LV free wall as a consequence of the lower ventricular pressures (Laplace’s law). The crescent shape and the thin wall make ...
Tetralogy of Fallot
Tetralogy of Fallot

... leads to ‘hypercyanotic spells’, which are a classical symptom of TOF. The child becomes deeply cyanosed after an episode of crying and may become limp and unresponsive. This is a sign of acute reduction in pulmonary blood flow associated with sudden increase in the dynamic obstruction to the right ...
Chapter 18 Powerpoint B
Chapter 18 Powerpoint B

... Heart Physiology: Sequence of Excitation • Subendocardial conducting network – Complete pathway through interventricular septum into apex and ventricular walls – More elaborate on left side of heart – AV bundle and subendocardial conducting network depolarize 30X/minute in absence of AV node input ...
CAUSE: Cardiac arrest ultra-sound exam
CAUSE: Cardiac arrest ultra-sound exam

... for experienced practitioners manual is dedicated to this topic and its practical application.2 Hughes et al. provided a list of the etiologies of PEA in the order of frequency and ease of reversal.3 He lists the top five conditions as hypoxia, hypovolemia, tension pneumothorax, pericardial tamponad ...
Invasive and non-invasive methods for cardiac output measurement
Invasive and non-invasive methods for cardiac output measurement

... This method uses a special thermistor – tipped catheter (Swan-Ganz catheter) inserted from a central vein into the pulmonary artery. A cold solution of D/W 5% or normal saline (temperature 0 oC) is injected into the right atrium from a proximal catheter port. This solution causes a decrease in blood ...
docx Impact of cardiac rehabilitation services on
docx Impact of cardiac rehabilitation services on

... given a cardiac rehabilitation program that is inclusive of an exercise component. Options should be offered to the patient in a wide range. They should be encouraged to actually attend to the options that have been offered to them, but which are appropriate to their particular needs. However, in ca ...
Multi-contrast late enhancement CMR determined gray zone and
Multi-contrast late enhancement CMR determined gray zone and

... is partially attributable to malignant ventricular arrhythmias (VA) after myocardial infarction (MI). These malignant arrhythmias can be terminated by implantable cardioverter-defibrillator (ICD) therapy. Currently, poor left ventricular ejection fraction (LVEF) is the primary index that is used to ...
Current Status of Transcatheter Aortic Valve Replacement
Current Status of Transcatheter Aortic Valve Replacement

... Surgical aortic valve replacement (SAVR) has long been the mainstay of therapy for severe aortic stenosis. However, transcatheter aortic valve replacement (TAVR) is now generally accepted as the new standard of care for patients with symptomatic aortic stenosis who are not candidates for open surger ...
Upregulation of the cardiac homeobox gene Nkx2–5 (CSX) in feline
Upregulation of the cardiac homeobox gene Nkx2–5 (CSX) in feline

... been shown to evoke certain changes in cardiac transcription. Several gene products are reexpressed that are only otherwise expressed during cardiac development. Examples include b-myosin heavy chain (17, 23, 25), ANF (28), a-skeletal actin (26), and atrial myosin light chain-1 (16). This suggests t ...
R21 - American College of Radiology
R21 - American College of Radiology

... a region of interest (ROI) is placed on the wall and a Hounsfield unit (HU) measurement is obtained that represents an average pixel value. This measurement can be performed on unenhanced gated CT study, often a calcium-scoring examination, and it has also been attempted with CTA. Optimally, it shou ...
Transcatheter Heart Valve Procedures
Transcatheter Heart Valve Procedures

... 1. Existence of a full (circumferential) RVOT conduit that was equal to or greater than 16 mm in diameter when originally implanted, AND 2. Dysfunctional RVOT conduits with a clinical indication for intervention, AND either of the following: • regurgitation: ≥ moderate regurgitation, AND/OR • stenos ...
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function
Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function

... iastolic dysfunction significantly influences prognosis in chronic heart disease across multiple etiologies; it is present in virtually all patients with heart failure1– 4 as well as in less severe conditions.5–7 From a mechanistic point of view, it can be traced to abnormalities of left ventricular ...
angina
angina

... 3. Patients with careers that involve the safety of others (e.g., airline pilots) who have questionable symptoms, suspicious or positive noninvasive tests. 4. Patients with aortic stenosis or hypertrophic cardiomyopathy and angina in whom the pain could be due to CAD. 5. Male patients aged 45 and fe ...
Back
Back

... degradation of thousands of lives. Many of those affected by these arrhythmias do not even know that they have them, and therefore, are not being treated. As the treatment for heart disease continues to progress, the diagnosis of the arrhythmias becomes more and more important. By catching heart arr ...
Exercise Training Alters Left Ventricular Geometry
Exercise Training Alters Left Ventricular Geometry

... in hypertensive rats. Dahl salt-sensitive rats fed a high-salt diet from 6 weeks of age were assigned to sedentary or exercise (swimming)-trained groups at 9 weeks. Exercise training attenuated the development of heart failure and increased survival, without affecting blood pressure, at 18 weeks. It ...
Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension
Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension

... Normal blood levels range from 0.7 to 1.0 µg/mL (Redalieu et al., 1968). Doses of 30–60 mg/day (~ 1 kg of body weight) are generally recommended to prevent CoQ10 deficiency and to maintain normal serum concentrations. However optimum clinical benefit requires above normal CoQ10 blood levels which may ...
Comprehensive Bio‐Imaging Using Myocardial Perfusion Reserve
Comprehensive Bio‐Imaging Using Myocardial Perfusion Reserve

... proportions. Unpaired Student t-tests were used to compare continuous variables. Group differences between continuous variables were tested using analysis of variance with Bonferroni adjustment for multiple comparisons. Differences between ordinal variables were tested using the exact Mann–Whitney t ...
Chapter 02 The Cardiovascular System
Chapter 02 The Cardiovascular System

... 36. The AV node has several important qualities that help the heart function effectively. All of these are qualities of the AV node EXCEPT: A. Causes the delay of electrical impulses, which limits the number of impulses traveling to the ventricles B. Allows for a delay to provide time for the blood ...
Implantable Cardioverter Defibrillators
Implantable Cardioverter Defibrillators

... Spontaneous diagnostic type 1 ECG with positive history of syncope, seizure or nocturnal agonal respiration after noncardiac causes have ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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