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I. Sinus rhythms and arrhythmias A. Records the impulse originating
I. Sinus rhythms and arrhythmias A. Records the impulse originating

... D. Clinical Presentation – dependent on the rate and patient tolerance of the rate E. Treatment – directed at the underlying cause IV. Sinus Bradycardia A. Characterized by heart rate less than 60 B. Criteria: 1. Rhythm: regular 2. Heart rate: 40 -60 3. QRS: less than 0.10 4. P wave: only one preced ...
Evaluation of Ejection Fraction in Patients with cardiac
Evaluation of Ejection Fraction in Patients with cardiac

... characterized by a dilated left ventricular chamber and systolic dysfunction. DCM commonly results in congestive heart failure (CHF) and is the most common form of cardiomyopathy and reason for cardiac transplantation in adults and children.1 Until recently, lifestyle changes, drugs and, sometimes, ...
Therapeutic effect of MG132 on diabetic cardiomyopathy is
Therapeutic effect of MG132 on diabetic cardiomyopathy is

... inflammation, which initiates the late development of cardiac remodeling and dysfunction (1, 12, 27, ...
Pharmacology Objectives 9
Pharmacology Objectives 9

... concentration. Plasma digoxin concentration is not extremely useful because there isn’t a clear value for toxic blood concentration. This is because other factors such as serum K+ concentration, when low, will result in digoxin toxicity at serum digoxin levels that would otherwise be “therapeutic”. ...
Cardiac Arrhythmias: Diagnosis and Management. The Tachycardias
Cardiac Arrhythmias: Diagnosis and Management. The Tachycardias

... Summary of review: Normal cardiac rhythm originates from impulses generated within the sinus node. These impulses are conducted to the atrioventricular node where they are delayed before they are distributed to the ventricular myocardium via the His-Purkinje system. Abnormalities in cardiac rhythm a ...
Pericardial Disease
Pericardial Disease

... most evident at the posterior cardiac interface (Fig. 4). The pericardium can usually be visualized in all standard echocardiographic windows such that diffuse pericardial pathology can be observed in most views. Localized pericardial disease, such as loculated fluid collections or hematomas, may re ...
Intermediate Outcome of Transcatheter Closure of Secundum Atrial
Intermediate Outcome of Transcatheter Closure of Secundum Atrial

... the RV free wall and interventricular septum (IVS) in color-coded tissue Doppler mode was taken, and ≥3 beats were acquired with suspended respiration and a frame rate was adjusted at 150 frames/second. Care was taken to align the segment in the center of the sector to avoid errors due to the angle ...
Effect of Plethora and Hemorrhage on Left Ventricular Volume and
Effect of Plethora and Hemorrhage on Left Ventricular Volume and

... In some cases a small polyethylene tube was passed into the pleural space through the lumen of a blunt 15-gage needle. "Effective" pressure within the left ventricle was calculated by subtracting the intrapleural pressure from the intraventricular pressure. Femoral arterial pressure was measured wit ...
A review of spontaneous closure of ventricular septal defect
A review of spontaneous closure of ventricular septal defect

... catheterization—and can be proven by pathological evidence at necropsy. There are two major types of VSD, membranous and muscular, as well as the perimembranous variety, which comprises variable portions of the adjacent muscular septum but lacks the membranous septum. VSD appears either as an isolat ...
Selected Aortic Valve Procedures
Selected Aortic Valve Procedures

... The Ross procedure is not recommended for patients with bicuspid valves and aortic regurgitation or aortic dilation if other alternatives are available. (Level of evidence C) Guidelines from the European Society of Cardiology (Erbel, et al., 2014) state that In most cases of aortic insufficiency ass ...
QRS Complexes (Fast and Easy ECGs, Shade / Wesley)
QRS Complexes (Fast and Easy ECGs, Shade / Wesley)

... are often the result of intraventricular conduction defect which usually occurs due to right or left bundle branch block. •  Wide QRS complexes may be seen in aberrant conduction, ventricular preexcitation and with a cardiac pacemaker. ...
Right Heart Adaptation to Pulmonary Arterial€Hypertension
Right Heart Adaptation to Pulmonary Arterial€Hypertension

... with increased right atrial pressure and a higher likelihood of death or transplantation. Similarly, acute kidney injury has also been associated with worse outcomes after acute RHF (28). Although congestive hepatopathy is often observed in patients with RHF and PAH, cirrhosis is a late complication ...
Image-based large-eddy simulation in a realistic left heart
Image-based large-eddy simulation in a realistic left heart

... provide information on cardiac abnormalities. However, in clinical routine, hemodynamics is mostly observed indirectly through global variables as the cardiac output in order to assess the cardiac performance. Indeed, a synthetic description of the available information and its relation with the hea ...
7 The Pericardium
7 The Pericardium

... and may help preserve left ventricular systolic function as measured by left ventricular +dP/dt following transplantation, but that these relative effects were not equivalent for both ventricles. The nonsymmetrical results between the left and right ventricles under constant filling preload and afte ...
Isotretinoin (13-cis-retinoic acid)-associated premature ventricular
Isotretinoin (13-cis-retinoic acid)-associated premature ventricular

... pediatric populations, PVCs commonly result in an irregular pulse as in our patient. PVCs can result from hypoxia, hypovolemia, electrolyte abnormalities, medications, or irritation from intracardiac monitoring or pacing catheters, or it can be idiopathic in nature. An exact evaluation of children p ...
Interventional Cardiology
Interventional Cardiology

... The indications for catheter ablation of arrhythmias in the CHD population are similar to the non-CHD population including significant symptoms, syncope or hemodynamic instability particularly when there has been failure or intolerance of medical therapy. Antiarrhythmic medications, such as beta blo ...
Prevalence of left ventricular dysfunction in a UK community sample
Prevalence of left ventricular dysfunction in a UK community sample

... double over the next 20 years.3 This demographic shift, coupled with improved case fatality rates in acute myocardial infarction and incident HF, has led to a significant increase in HF prevalence.4 The burden of HF for both primary and secondary care will escalate substantially over the next 20 year ...
cardio i - jan 2015
cardio i - jan 2015

... congestive heart failure (rarely seen with MI). ...
Wnt signaling in right ventricular remodeling
Wnt signaling in right ventricular remodeling

... a female predisposition of 2:1 and an average mean PA pressure of 55 mmHg [9]. Most patients with PAH present exertional dyspnea, indicating an inability to increase cardiac output. Other reported symptoms include: fatigue or weakness, syncope and angina pectoris which are indicative of right heart ...
Differential diagnosis of broad complex tachycardia
Differential diagnosis of broad complex tachycardia

... morphological appearance of QRS complexresult from direct myocardial activation ...
Straight Back Syndrome - bangkokmedjournal.com
Straight Back Syndrome - bangkokmedjournal.com

... thickening of the mitral leaflet >5 mm and leaflet displacement >2 mm. The ECG sign in a classic MVP is normal or may show ST-segment and T wave abnormalities especially in lead II, III and a VF.8 If the classic signs of the mitral abnormality are found on the echocardiography or on the MRI in certa ...
The ECGs that will be read around the world—and save lives of
The ECGs that will be read around the world—and save lives of

... Sudden cardiac death (SCD) is the leading cause of death in athletes during sport. Whether obtained for screening or diagnostic purposes, an ECG increases the ability to detect underlying cardiovascular conditions that may increase the risk for SCD. In most countries, there is a shortage of physicia ...
Coronary Venous Anatomy and its Relevance Suma HY‡, Hariharan
Coronary Venous Anatomy and its Relevance Suma HY‡, Hariharan

... Morique et al., 2005). In the present study, Suma, Coronary venous anatomy ...
Non-Invasive Transcutaneous Pacing
Non-Invasive Transcutaneous Pacing

... 340 ms for pacing rates less than or equal to 80 pulses per minute (PPM), and approximately 240 ms for pacing rates greater than or equal to 90 PPM. With the pacer on, the defibrillator marks intrinsic beats on the R-wave with an arrow on the Efficia DFM100. The intrinsic beats are also marked in th ...
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline

... Clinical Implementation ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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