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More on the right ventricle in pulmonary hypertension Robert Naeije and Stefano Ghio
More on the right ventricle in pulmonary hypertension Robert Naeije and Stefano Ghio

... Decreased RVEF and PVR is associated with a decreased survival rate in PAH patients under targeted therapies http://ow.ly/EBK8U In the present issue of the European Respiratory Journal, COURAND et al. [1] report on the prognostic relevance of radionuclide angiography of the right ventricle (RV) in a ...
specified populations
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... disease and processes for improving event survival is the business of the physicians However, they must receive the cooperation of the patients who must come to the hospital, accept to be treated, adhere to drug therapy, and follow-up on treatment The hospitals must also be sufficiently equipped wit ...
Atrial septal defect - Great Ormond Street Hospital
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... any symptoms at all. Frequent chest infections can be a sign that the oxygenation process is not working efficiently due to extra blood flow to the lungs. Large defects can cause extra strain on the heart causing the right-hand side of the heart to dilate (stretch). Babies with large defects may be ...
Echocardiographic parameters in healthy young adult Sphynx cats
Echocardiographic parameters in healthy young adult Sphynx cats

... The following classification was used according to Kittleson’s advice to breeders (Winn Feline Foundation 2005, updated in 2006, 2009 and 2011) HCM positive: Clinical suspicion of HCM/HOCM by clinical examination (heart murmur, gallop rhythm, tachycardia), familial screening of the disease in first or ...
DIRECTIONS: Each group of questions below consists of a number
DIRECTIONS: Each group of questions below consists of a number

... (E) complete obstruction of airflow to one lobe of the lung. 28. As a result of an acute myocardial infarction, pulmonary venous pressure increases to 12 mmHg (normal = 5 mmHg). If cardiac output is normal, which of the following changes from normal in pulmonary arterial pressure would most likely o ...
Doppler echocardiographic quantitation of cross
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Regulation of Cardiac Output Through Stroke Volume
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... (comparing complexes of the same cycle length) and during inspiration the pulmonic component moved less than 0.02 second. There was no delay in the onset of the right ventricular pressure pulse in the postoperative catheterization study. There was no clinical evidence of right ventricular failure. P ...
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Slide 1
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Haider Sabhan Treatment of Cardiac Arrhythmias in the Emergency
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... Not many things can raise the anxiety level in a physician more than a call to the emergency department about a patient who has a cardiac arrhythmia. Despite a significant amount of time throughout medical training being dedicated to understanding the mechanisms and treatments of cardiac rhythm dist ...
PowerPoint プレゼンテーション
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... workload and helps to maintain cardiac function. If the condition is prolonged, however, it can develop into heart failure. New insight into how that transition occurs has been obtained in a study of a mouse model of cardiac hypertrophy. As the animal's heart enlarges, new blood vessels develop to s ...
Mitral annular plane systolic excursion (MAPSE)
Mitral annular plane systolic excursion (MAPSE)

... MAPSE is suggested to be primarily representative of subendocardial, longitudinally oriented, myocardial fibres compared to the subepicardial, circumferential fibres measured by LVEF, and is known to detect more subtle abnormalities of LV function [7, 18]. This is seen in patients with increasing ag ...
Ventricular Structure and Function
Ventricular Structure and Function

... Consecutive patients with suspected HFPEF were invited to participate. HFPEF was suspected in the presence of the following: (1) symptoms or signs of heart failure; (2) normal or mildly reduced LV systolic function (LVEF >50%); and (3) evidence of abnormal LV relaxation or diastolic stiffness.10 Rea ...
Nonsustained ventricular tachycardia
Nonsustained ventricular tachycardia

... Introduction Nonsustained ventricular tachycardia (NSVT) is one of the most common problems encountered in modern clinical cardiology. The term, defined as 3 or more consecutive beats arising below the atrioventricular node with a rate >120 beats/min and lasting less than 30 s,1–3 denotes an electro ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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