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Prevention and Management of Chronic Heart Failure in Patients at
Prevention and Management of Chronic Heart Failure in Patients at

... or death. An HbA1c level ⱖ10, relative to HbA1c ⬍7, was associated with 1.56-fold (95% CI, 1.26 to 1.93) greater risk of HF.31 Diabetes is not only a risk factor for HF in patients without structural heart disease, but it is also associated with a worse outcome once a cardiac disease (eg, a myocardi ...
Aortic stenosis and role of multi-detector row computed tomography
Aortic stenosis and role of multi-detector row computed tomography

... a long latent period, patients remain asymptomatic. However, it should be emphasized that duration of the asymptomatic phase varies widely among individuals. Sudden cardiac death is a frequent cause of death in symptomatic pts but appears to be rare in the asymptomatic (≤ 1% per year). Reported mean ...
The Cardiovascular System: The Heart
The Cardiovascular System: The Heart

... The pericardial cavity surrounding the heart is formed by the visceral pericardium and the parietal pericardium. The relationship between the heart and the pericardial cavity can be likened to a fist pushed into a balloon. ...
Chapter 12 - Napa Valley College
Chapter 12 - Napa Valley College

... The pericardial cavity surrounding the heart is formed by the visceral pericardium and the parietal pericardium. The relationship between the heart and the pericardial cavity can be likened to a fist pushed into a balloon. ...
The Cardiovascular System: The Heart
The Cardiovascular System: The Heart

... The pericardial cavity surrounding the heart is formed by the visceral pericardium and the parietal pericardium. The relationship between the heart and the pericardial cavity can be likened to a fist pushed into a balloon. ...
Common RyR2 variants associate with ventricular arrhythmias and
Common RyR2 variants associate with ventricular arrhythmias and

... hospitalized or during their annual physical examination. All subjects underwent transthoracic echocardiography to evaluate valves, atrial and ventricular chamber dimensions, thickness of the ventricular walls and interventricular septum, right and left ventricular function, wall motion abnormalitie ...
Nonsustained ventricular tachycardia
Nonsustained ventricular tachycardia

... Introduction Nonsustained ventricular tachycardia (NSVT) is one of the most common problems encountered in modern clinical cardiology. The term, defined as 3 or more consecutive beats arising below the atrioventricular node with a rate >120 beats/min and lasting less than 30 s,1–3 denotes an electro ...
Commentaries on Viewpoint: Is left ventricular volume during
Commentaries on Viewpoint: Is left ventricular volume during

... our understanding of the age-old question about the meaning of end diastole of the left ventricle as well as its corollary, diastolic suction. The discussion omits several additional mechanisms that may also be contributing to left ventricular (LV) filling. One plausible explanation of the recoil ge ...
Pediatric Ventricular Fibrillation Pulseless Ventricular Tachycardia
Pediatric Ventricular Fibrillation Pulseless Ventricular Tachycardia

... · DO NOT HYPERVENTILATE: If no advanced airway (BIAD, ETT) compressions to ventilations are 30:2. If advanced airway in place ventilate 8 – 10 breaths per minute with continuous, uninterrupted compressions. · Do not interrupt compressions to place endotracheal tube. Consider BIAD first to limit inte ...
Innocent Murmur
Innocent Murmur

... pulmonary artery associated with rapid flow during the early ejection period of the right ventricle (2/3 of the stroke volume leaves the ventricle during the first 1/3 of systole). It is commonly heard in the young patient whose circulation is dynamic. It may be less prominent when the patient is er ...
Left Ventricular Assist Device as a Bridge to Recovery
Left Ventricular Assist Device as a Bridge to Recovery

... transplant. Some studies have even advocated for the use of devices in INTERMACS class 4-6 [24]. With this in mind, overall recovery rates remain low in the majority of large scale studies which have investigated LVAD use over the past 15 years. This impresses upon us the importance of patient selec ...
Diagnosing primary diastolic heart failure
Diagnosing primary diastolic heart failure

... Diagnosing primary diastolic heart failure With the increasing refinement of methods to uncover early phases of cardiac failure, we have, over the past two decades, witnessed the emergence of diastolic dysfunction and diastolic failure of the heart as separate, widely recognized clinical entities. W ...
1-Anatomy of the Heart
1-Anatomy of the Heart

... • Anterior cusp : lies anteriorly and to right. • Posterior cusp : lies posteriorly and to left. o The atrial surfaces of the cusps are smooth, while ventricular surfaces give attachment to chordae tendinae. ...
Gerbode Defect—A Rare Defect of Atrioventricular Septum and
Gerbode Defect—A Rare Defect of Atrioventricular Septum and

... pulse wave,continuous wave and colour Doppler. This along with right atrial chamber enlargement, normal pulmonary artery end diastolic pressure and an unusually high Doppler echocardiogram gradient compared to the ventricular septal defect with shunting only at ventricular level lead us to the diagn ...
Single Arterial Trunk - Heart
Single Arterial Trunk - Heart

... grounds that the single arterial trunk did not fulfil the two criteria of a "true" truncus. They suggested that in most of the cases the single arterial trunk was a solitary pulmonary artery since it did not give rise to the coronary arteries. In their view, the commonest cause of a single ventricle ...
Tricuspid Valve
Tricuspid Valve

...  Final valves derived from endothelial-mesenchymal cells with neural crest cells from the brachial arches  Valves (Semilunar) have 3 equal cusp-shaped leaflets  Aortic valve incorporates coronary arteries  Atrioventricular (AV) valves = mitral and tricuspid  Final valves derived entirely from e ...
Cardiac Pacemakers - Medical Clinics 100
Cardiac Pacemakers - Medical Clinics 100

... This pacemaker is made for us in the laboratories of the hospital. A total of 63 implants with this pacemaker has been made. Sixty-two of these were in patients with complete A-V block; one was implanted on the atrium of a patient with Stokes-Adams episodes due to repetitive transient atrial arrest. ...
Aortic Insufficiency
Aortic Insufficiency

... of the mitral valve and may be absent in severe acute regurgitation. The second heart sound is also soft, and a third heart sound is frequently present due to the rapid early diastolic filling of the ventricle. A fourth heart sound is uncommon. In contrast to chronic aortic regurgitation, the diasto ...
Comments on the 2015 ESC Guidelines for the Management of
Comments on the 2015 ESC Guidelines for the Management of

... I. Fernández-Lozano et al / Rev Esp Cardiol. 2016;69(2):94-101 ...
Chapter 15 Heart Physiology PPT
Chapter 15 Heart Physiology PPT

... Regulation of Cardiac Cycle •cardiac center regulates autonomic impulses to the heart ▪ parasympathetic impulses decrease heart action ▪ sympathetic impulses increase heart action ▪ concentration of various ions ▪ potassium and sodium decrease heart action ▪ calcium increases heart action • physica ...
`End-stage` heart failure therapy - Heart
`End-stage` heart failure therapy - Heart

... cardiac dysfunction and dilatation.8 Considering patients with a systemic RV, the long-term outcome is directly related to a balanced ventricular interaction and the competence of the systemic atrioventricular valve.9 Dilatation of the systemic ventricle is prevented by subpulmonary (left) ventricul ...
Influence of pneumoperitoneum on left ventricular filling pressures
Influence of pneumoperitoneum on left ventricular filling pressures

... mates of LV filling pressures than other methods. Brain-natriuretic peptide (BNP) is a cardiac neurohormone secreted from the ventricles in response to ventricular volume expansion and pressure overload6-7. BNP levels may also reflect diastolic dysfunction8-10. This hormone has become firmly establi ...
Atrioventricular node ablation: patient monitoring and pacing rate
Atrioventricular node ablation: patient monitoring and pacing rate

... T wave with the device, direct pro-arrhythmic effects of LV pacing itself (see below),1 and finally torsades de pointes due to a bradycardia-dependent prolongation in the QT interval. A phase of electrical instability due to an initial and then slow adaptation of repolarization has been attributed t ...
Automatic Global and Regional Phase Analysis from Gated
Automatic Global and Regional Phase Analysis from Gated

... are calculated for the histogram (a tabulation of distribution frequencies) of FFH phase angles, and their notations in this article are as follows: m R, mean over region R; s R, SD over region R; MR, mode over region R (i.e., the location of the peak of the phaseangle histogram for region R); bR, b ...
Surgical and Transcatheter Mitral Valve Repair for Severe Chronic
Surgical and Transcatheter Mitral Valve Repair for Severe Chronic

... common disorder affecting nearly 10% of the US population aged >75 years and is associated with increased morbidity and mortality in the setting of left ventricular (LV) dysfunction and heart failure symptoms. Mitral valve repair or replacement improves morbidity and mortality in appropriate clinica ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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