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Diastolic Heart Failure - American Academy of Family Physicians
Diastolic Heart Failure - American Academy of Family Physicians

... changes tend to decrease ventricular compliance,making patients with diastolic dysfunction more susceptible to the adverse effects of hypertension, tachycardia, and atrial fibrillation. Diagnosis The signs and symptoms of heart failure are nonspecific (dyspnea, exercise intolerance, fatigue, weaknes ...
Effect of Hyperoxia on Left Ventricular Function and Filling
Effect of Hyperoxia on Left Ventricular Function and Filling

... consequences in patients with chronic obstructive lung disease or acute respiratory failure, as gas exchange may be worsened by denitrogenation atelectasis and increased intrapulmonary shunting.1,2 Over the last 50 years, it has also been demonstrated3,4 that hyperoxia results in hemodynamic alterat ...
Death in Tecumseh, Michigan
Death in Tecumseh, Michigan

... such deaths among the study population. Deaths known or suspected to have occurred from conditions other than coronary heart disease were excluded from the analysis. Only a few prospective studies of predisposing factors among sudden fatalities have been reported. In general, the same nsk factors (h ...
Pacemaker Syndrome and Pacemaker Complications
Pacemaker Syndrome and Pacemaker Complications

... Pacemaker syndrome refers to the occurrence of symptoms relating to the loss of AV synchrony in patients with a pacemaker, ie the atria contract at the same time as paced ventricular contractions. [4] The result is decreased cardiac output in response to which the total peripheral resistance will in ...
August - Congenital Cardiology Today
August - Congenital Cardiology Today

... performing greater than 300 open-heart surgical procedures per year, 17 (28%) performing between 201 and 300, 19 (32%) performing between 101 and 200, and 3 (5%) performing less than 100. Pediatric residency programs were present at 90% of the hospitals, and pediatric critical care and pediatric car ...
Left Ventricular Hypertrophy in Hypertension
Left Ventricular Hypertrophy in Hypertension

... activity among men with hypertension or a substantial prevalence of clinically inapparent heart disease, associated with mild LVH, among apparently normal men. Longitudinal studies of physical activity, cardiac status, and cardiovascular morbidity will be needed to determine the cause. Influence of ...
Biventricular Pacemakers - Cardiac Resynchronization Therapy for
Biventricular Pacemakers - Cardiac Resynchronization Therapy for

... Fluid Index. It has been proposed that these data may be used as an early warning system of cardiac decompensation or to provide additional feedback enabling a physician to further tailor medical therapy. ...
SUDDEN CARDIAC DEATH IN YOUNG PEOPLE – FORENSIC
SUDDEN CARDIAC DEATH IN YOUNG PEOPLE – FORENSIC

... biological individuality. The set of genetic information specific to the body defines the human genome. According to Hoffman’s study, in 50-60 % cases of sudden cardiac death in children are found genetic heart disease. English and Dutch studies show that between 22-28 % of first degree relatives of ...
Pediatric Cardiomyopathies
Pediatric Cardiomyopathies

... Cardiomyopathy is a chronic disease of the heart muscle (myocardium), in which the muscle is abnormally enlarged, thickened, and/or stiffened. The weakened heart muscle loses the ability to pump blood effectively, resulting in irregular heartbeats (arrhythmias) and possibly even heart failure. Cardi ...
AHEART July 46/1 - AJP
AHEART July 46/1 - AJP

... delays the onset and slows down the rate of relaxation, whereas an increase in afterload late in systole abbreviates contraction time and increases the rate of relaxation (5). In isolated heart studies, interventions designed to increase afterload immediately after aortic valve opening increased the ...
Interpreting ECGs with Confidence: Part 2
Interpreting ECGs with Confidence: Part 2

... defined as 3 or more SV beats in succession. SVT is usually associated with significant heart 4 disease and atrial enlargement. A unique form of SVT is associated with an accessory pathway connecting the atria and ventricles. When occurring as a paroxysm, the rhythm is fast and regular, often with a ...
Objectives - Contemporary Forums
Objectives - Contemporary Forums

... Uncommon causes ...
Learning Resources - San Jose State University School of Nursing
Learning Resources - San Jose State University School of Nursing

... around pacemaker to heal and seal unit in place. b. Signs and symptoms that warrant a call to the physician’s office If you experience the following signs and symptoms, notify your physician’s office: redness or swelling at incision site, skin surrounding incision very warm and tender to touch, puru ...
Mitral Valve Prolapse
Mitral Valve Prolapse

... benefit from cessation of such stimulants as smoking, alcohol, or caffeine. In addition, treatment with β-blockers is effective in reducing chest pain and palpitations. In patients with recurrent palpitations, unexplained syncope, or episodes of nonsustained ventricular tachycardia, further investig ...
Ventricular Fibrillation: A Pediatric Problem
Ventricular Fibrillation: A Pediatric Problem

... Wolff-Parkinson-White Syndrome; Ventricular Septal Defect (VSD Pediatric Residency Program Sometimes babies born with moderate ventricular septal defects will have problems with congestive In lone atrial fibrillation, the cause is often unclear, and serious complications are rare. Control of ventric ...
Misdiagnosis of Arrhythmogenic Right Ventricular
Misdiagnosis of Arrhythmogenic Right Ventricular

... ARVD/C Misdiagnosis. Introduction: Diagnosis of arrhythmogenic right ventricular dysplasia/ cardiomyopathy (ARVD/C) has major implications for the management of patients and their first-degree relatives. Diagnosis is based on a set of criteria proposed by the International Task Force for Cardiomyopa ...
Deakin Research Online - DRO
Deakin Research Online - DRO

... for an increase in stroke volume, thereby compensating for a low heart rate. According to the Frank-Starling Law (see Figure 3), an increase in ventricular filling results in greater lengthening of ventricular muscle fibres, which, in turn, leads to increased muscle shortening, an increased stroke v ...
Successful simultaneous ipsilateral stenting of common iliac artery
Successful simultaneous ipsilateral stenting of common iliac artery

... 18-F introducer sheath and delivery catheter should be >6 mm. This technique has become popular due to a number of advantages, including shorter procedure and recovery times,[3] less postprocedural pain,[4] and ability to perform procedure under conscious sedation.[5] In addition, a meta-analysis co ...
Effects of Flecainide and Propafenone on Systolic
Effects of Flecainide and Propafenone on Systolic

... agents, related side effects. The flecainide are well known,’2 ...
Implantable Cardiac Loop Recorders
Implantable Cardiac Loop Recorders

... (2010) have laid out a strategy that allows for using short-term or longer-term monitoring of cardiac rhythms. Unfortunately, determination of the arrhythmic cause of stroke through ILR evaluation has a low level of positive yield. The American Heart Association/American College of Cardiology and th ...
Outcome of Watchful Waiting in Asymptomatic Severe Mitral
Outcome of Watchful Waiting in Asymptomatic Severe Mitral

... guidelines published by the American Society of Echocardiography and the European Association of Echocardiography.20 LV diameters, fractional shortening, and ejection fraction, as well as systolic pulmonary artery pressure (using tricuspid regurgitant velocity), ...
Relationship of the Pulmonary Artery End
Relationship of the Pulmonary Artery End

... a which could be identified only at the basal heart rate was identical to the LVEDP. In the five patients studied during atrial fibrillation, the LVEDP was found to be equal to the PAEDP in one case and lower than the PAEDP in four, in three of which PVR was increased. The relationship between these ...
The Veterinary Journal - Repositório Aberto da Universidade do Porto
The Veterinary Journal - Repositório Aberto da Universidade do Porto

... fuse and may not be distinguishable. Nevertheless, the use of high-speed tracing (100–200 m/s) allowed the assessment of E- and A-wave peak flow velocities, even at elevated heart rates, but deceleration time of the E-wave could not be measured. In recent years, TDI has emerged as a new modality that ...
Annals of Cardiology and Cardiovascular Diseases Open
Annals of Cardiology and Cardiovascular Diseases Open

... Dilatation of the ascending aorta may be encountered due to different etiologies such as atherosclerosis, collagen metabolism disorders, degenerative processes in the elderly, cystic medial necrosis and Marfan’s disease [1]. Depending on the underlying pathological mechanism, guidelines generally ad ...
Optimal Control Aspects of Left Ventricular Ejection - IME-USP
Optimal Control Aspects of Left Ventricular Ejection - IME-USP

... it is by no means clear what performance criteria are relevant for biological systems, optimization seems to be a worthwhile viewpoint both for theoretical analysis, as for suggesting new experiments. Specifically, in the present problem, our aim is to apply dynamic optimization theory to the mechan ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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