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Diastolic LV function and HFNEF
Diastolic LV function and HFNEF

... – 1) exaggerated↑ SBP after small ↑ in LVEDV – 2) a marked ↑ SBP after a further ↑ in art elastance in presence of a high ES elastance – 3) limited systolic reserve due to ↑ baseline ES elastance – 4) ↑ cardiac work to deliver a given CO – 5) a direct influence of ↑ art elastance on LV diast functn ...
Spatio-Temporal Shape Parameterization of the Human Ventricles
Spatio-Temporal Shape Parameterization of the Human Ventricles

... Introduction of several auxiliary medical data such as age, gender, position, ECG signal, blood pressure and respiration ...
Heart Physiology
Heart Physiology

... each ventricle in a minute  CO = heart rate (HR) multiplied by stroke volume (SV)  SV = the volume of blood pumped by each ventricle with each beat  Normal CO is approximately 5 liters ...
S0735109714023572_mmc1
S0735109714023572_mmc1

... Software Inc, San Diego, CA) and SPSS version 20 (SPSS Inc. Chicago, Illinois). Normal distribution was tested and if necessary logarithm transformation was performed. Cardiac MRI measurements, CSA, phosphorylation and protein content of the sarcomeric proteins were analyzed by independent t-test or ...
Warning Symptoms and Family History in Children and Young
Warning Symptoms and Family History in Children and Young

... letes is the detection of silent cardiovascular abnormalities that predispose to SCD.16 In 1996 the AHA provided consensus recommendations for the preparticipation cardiovascular evaluation of athletes, which includes 12 elements of a personal history, family history, and the physical examination.9 ...
Ch_21_lecture_presentation
Ch_21_lecture_presentation

... • The Left Ventricle • Has the thickest wall • Needed for strong contractions to pump blood throughout the entire systemic circuit • Compare to the right ventricle, which has a thin wall since it only pumps blood through the pulmonary circuit ...
Management of arrhythmias in heart failure. What a practicing
Management of arrhythmias in heart failure. What a practicing

... the underlying arrhythmia [43]. Patients who receive appropriate shocks were noted to have substantially higher ventricular arrhythmia burden and poor survival compared to patients treated with ATP-alone [44]. Adjunctive pharmacotherapy, in addition to ATP, was shown to reduce the incidence of shock ...
The Assessment of Left Ventricular Ejection Fraction in Patients with
The Assessment of Left Ventricular Ejection Fraction in Patients with

... a useful non-invasive means of assessing left ventricular performance. In contrast to cineangiography it makes no assumption about changes in geometry of the left ventricle; it does not involve the injection of contrast material; it provides an average value over many cardiac cycles rather than over ...
Magnetic Resonance and Computed Tomography Imaging of
Magnetic Resonance and Computed Tomography Imaging of

... exact prevalence of this condition is not known, but is estimated to be around 1 in 5000. The disease rarely manifests before adolescence and usually presents in the second or third decade of life (1). Affected individuals are often men who have an athletic lifestyle. Presenting symptoms vary from a ...
Inter-ventricular septum: New observations on the structure and
Inter-ventricular septum: New observations on the structure and

... ventricle. Ventricular interdependence is particularly evident in the neonatal myocardium [37]. In adult clinical practice the aphorism “left heart failure begets right heart failure” [1,62,63] is also well known. Right ventricular pressure and/or volume overload stretches the right ventricular free ...
Echocardiographic assessment of right heart indices in dogs with
Echocardiographic assessment of right heart indices in dogs with

... ABSTRACT: The aim of this study was to evaluate right ventricular (RV) remodeling and right heart failure associated with different causes of elevated pulmonary arterial pressure (PAP) in dogs. In total, 169 client-owned dogs with tricuspid regurgitation (TR) and 40 client-owned clinically healthy d ...
Ventricular Structure and Function
Ventricular Structure and Function

... with data of 500 consecutive study participants, accounting for height, weight, sex, and age. Only variables with P values <0.01 were left in the linear regression models with stepwise selection. 95% confidence intervals and P values of the corresponding test were calculated for the regression coeff ...
Instructions
Instructions

... is discharged from the hospital after cardiac surgery or PCI to hospice care (inpatient or home with hospice care) and is still alive 30 days after the discharge from the hospital will be analyzed as a live discharge. All patients discharged to a hospice or home with hospice care should continue to ...
Antiarrhythmic drug therapy in patients with supraventricular or
Antiarrhythmic drug therapy in patients with supraventricular or

... emergencies depends on the clinical presentation. If the patient presents with acute hemodynamic collapse or congestive heart failure, emergent direct-current synchronized shock is indicated (Fig. 1). Atrial flutter can most often be successfully cardioverted to sinus rhythm with energies less than ...
Pulmonary atresia with a ventricular septal defect
Pulmonary atresia with a ventricular septal defect

... my child grows up? Children who have pulmonary atresia with a VSD are always limited to some extent in their physical activities, but specific restrictions on exercise are usually not necessary. Although surgery can give a better quality of life, it is not possible to correct the heart abnormality a ...
Echocardiography Evaluation of Ventricular Septal Defect
Echocardiography Evaluation of Ventricular Septal Defect

... • Eisenmenger’s complex now rare • Endocarditis most serious complication. Closure of VSD reduces endocarditis risk by 50%. • May develop left heart dilation, aortic regurgitation, or PHTN as patients age • Need to be aware of double chambered RV, subaortic stenosis. Rarely these can develop even af ...
the influence of renal alograft function on cardiovscular status and
the influence of renal alograft function on cardiovscular status and

... absolute value of serum creatinine and creatinine clearence. Lost renal function is established risk factor for the development of complications and death from cardiovascular disease and infection (). The results of our study show that patients with LV hypertrophy before kidney transplantation had ...
Swan-Ganz RN ICU
Swan-Ganz RN ICU

... this translates into an Increased CO & MAP at a given Filling Pressure ! by increasing inotropic state, you increase both Pressure Work & Flow Work, thus, increasing myocardial oxygen consumption… ...
Preliminary Program - Knowledge Hub for Pathology
Preliminary Program - Knowledge Hub for Pathology

... (particularly for MR) is common and often life-saving. xxxiii With contemporary valve replacements, patient prognosis is good at 15-20 years. xxxiv Nevertheless, the not inconsequential mortality and morbidity of open surgical procedures has stimulated considerable interest and progress in minimally ...
Introduction
Introduction

... Atrial flutter is usually associated with mitral valve disease, pulmonary embolism, thoracic surgery, hypoxia, electrolyte disturbances and hypercalcemia. Atrial flutter results in poor atrial pumping since some parts of the atria are relaxing while other parts are contracting. Cardiac output decrea ...
Understanding Pediatric Cardiomyopathy
Understanding Pediatric Cardiomyopathy

... 25 percent chance of having an affected child. Some forms of cardiomyopathy caused by Barth syndrome or Duchenne muscular dystrophy can occur sporadically in boys or may be passed on from mother to son (X-linked transmission). In the latter, sons will be at a 50 percent risk of having the condition ...
Arrhythmogenic Right Ventricular Dysplasia
Arrhythmogenic Right Ventricular Dysplasia

... Arrhythmogenic right ventricular dysplasia (ARVD) is a disorder in which normal myocardium is replaced by fibrofatty tissue. This disorder usually involves the right ventricle, but the left ventricle and septum also may be affected. Although the exact prevalence of ARVD is unknown, it is thought to ...
Low-Gradient Aortic Stenosis
Low-Gradient Aortic Stenosis

... Key Words: valves 䡲 hemodynamics 䡲 surgery 䡲 cardiomyopathy 䡲 echocardiography ...
Current treatment of ventricular arrhythmias: State of
Current treatment of ventricular arrhythmias: State of

... approach is to place ECG leads on the patient on arrival in the electrophysiology laboratory and immediately record any spontaneous arrhythmias so that they can potentially be used to guide pace mapping if the arrhythmia becomes quiescent. Although pace mapping can be used to guide ablation, it is l ...
The Pacemaker Current: From Basics to the Clinics
The Pacemaker Current: From Basics to the Clinics

... myocardium decreases and the voltage range of activation shifts to voltages more negative than the resting potential; under these conditions, the I f current does not contribute to normal electrical activity.26,27 However, under specific pathological conditions such as cardiac hypertrophy and failur ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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