MAG, Nogo-A and NgR in Hippocampal Development and Regeneration TESIS DOCTORAL
... The question this thesis aims to address is, therefore, the role of myelin-associated inhibitors in the regeneration of cortical connections. The model we have used is the entorhino-hippocampal connection and the conceptual structure followed was i) characterizing the temporal expression of the prot ...
... The question this thesis aims to address is, therefore, the role of myelin-associated inhibitors in the regeneration of cortical connections. The model we have used is the entorhino-hippocampal connection and the conceptual structure followed was i) characterizing the temporal expression of the prot ...
Voltage-Dependent Switching of Sensorimotor Integration by a
... cardiac sac dilations that activate the sensory vpln is not continuously active and produces a slow motor rhythm with a period of ⬃10 – 40 sec (Selverston and Moulins, 1987). To investigate how expression of the cardiac sac rhythm may influence the pyloric network through vpln activation, sensory in ...
... cardiac sac dilations that activate the sensory vpln is not continuously active and produces a slow motor rhythm with a period of ⬃10 – 40 sec (Selverston and Moulins, 1987). To investigate how expression of the cardiac sac rhythm may influence the pyloric network through vpln activation, sensory in ...
07. Pons Internal Features 0102010-10-01 05:141.9
... Medial lemniscus: twists as it leaves the medulla, and lies horizontally in the ventral pontine tegmentum. The fibers from the cuneate nucleus are medial to those from the gracile nucleus. It carries proprioceptive & fine touch sensation from opposite side of body to the thalamus. Trigeminal lemnis ...
... Medial lemniscus: twists as it leaves the medulla, and lies horizontally in the ventral pontine tegmentum. The fibers from the cuneate nucleus are medial to those from the gracile nucleus. It carries proprioceptive & fine touch sensation from opposite side of body to the thalamus. Trigeminal lemnis ...
MicroRNA Regulation of CNS Myelination
... only in the spinal cord, and significantly weaker expression has been detected in the brain (Dugas et al., 2010; Zhao et al., 2010). In addition, only Zhao et al. (2010) were able to detect a functional role for miR-338 in promoting OL differentiation, whereas Dugas et al. (2010) did not. These diff ...
... only in the spinal cord, and significantly weaker expression has been detected in the brain (Dugas et al., 2010; Zhao et al., 2010). In addition, only Zhao et al. (2010) were able to detect a functional role for miR-338 in promoting OL differentiation, whereas Dugas et al. (2010) did not. These diff ...
Axons
... • Communication is very rapid, and may be unidirectional or bidirectional • Are important in: • Embryonic nervous tissue ...
... • Communication is very rapid, and may be unidirectional or bidirectional • Are important in: • Embryonic nervous tissue ...
Epilepsy in Small
... (after spiking), 10 times longer than the synaptic delay, d. This allows the active population to travel 10 steps before the neurons recover. For the Poisson model, the synaptic delay was set at 3.7 msec and a refractory time of 36 msec, whereas in the integrate-and-fire model, the synaptic delay w ...
... (after spiking), 10 times longer than the synaptic delay, d. This allows the active population to travel 10 steps before the neurons recover. For the Poisson model, the synaptic delay was set at 3.7 msec and a refractory time of 36 msec, whereas in the integrate-and-fire model, the synaptic delay w ...
Document
... code. Notch 1 is cleaved in the ectodomain by furin, while APP is cleaved by alfa and B-secretase. Both proteins are cleaved in their transmembrane domain by a gamma-secretase-like activity that is controlled by presinilin. Asterisks indicate the localization of mutations in the APP and preseilin-1 ...
... code. Notch 1 is cleaved in the ectodomain by furin, while APP is cleaved by alfa and B-secretase. Both proteins are cleaved in their transmembrane domain by a gamma-secretase-like activity that is controlled by presinilin. Asterisks indicate the localization of mutations in the APP and preseilin-1 ...
Paper: Temporal Convergence of Dynamic Cell Assemblies in the
... globus pallidus (GPe)], and one neuromodulator group [striatal tonically active neurons (TANs)] from behaving monkeys. MSNs and GPe neurons displayed sustained average activity to cue presentation. The population average response of MSNs was composed of three distinct response groups that were tempo ...
... globus pallidus (GPe)], and one neuromodulator group [striatal tonically active neurons (TANs)] from behaving monkeys. MSNs and GPe neurons displayed sustained average activity to cue presentation. The population average response of MSNs was composed of three distinct response groups that were tempo ...
Glutamate Receptors Form Hot Spots on Apical Dendrites of
... apparatus developed for infrared-guided laser photostimulation (Fig. 1, A and B), we were able to visually direct a 1-m spot of UV light onto the surface of the neuron of interest. Because the uncaging in the z-axis depends on the precise focus onto the center of the dendrite, the focal points of t ...
... apparatus developed for infrared-guided laser photostimulation (Fig. 1, A and B), we were able to visually direct a 1-m spot of UV light onto the surface of the neuron of interest. Because the uncaging in the z-axis depends on the precise focus onto the center of the dendrite, the focal points of t ...
PDF
... cessed differently to optimize visualization of the injection site and the labeled fibers. In our experiments, we observed that, after injections of biotinylated PHA-L into the pontine nuclei, we could not stain the injection site. It was possible, however, to locate the tissue damage by the pipette ...
... cessed differently to optimize visualization of the injection site and the labeled fibers. In our experiments, we observed that, after injections of biotinylated PHA-L into the pontine nuclei, we could not stain the injection site. It was possible, however, to locate the tissue damage by the pipette ...
Long?Term, Stable Differentiation of Human Embryonic Stem Cell
... of cells [5]. The plasticity and differentiation potential of HESCs have been demonstrated in recent in vitro studies where these cells were induced to evolve into specific neuronal and glial lineages to become mesencephalic dopaminergic neurons [6–8], motor neurons [9–11], and oligodendrocytes [12]. ...
... of cells [5]. The plasticity and differentiation potential of HESCs have been demonstrated in recent in vitro studies where these cells were induced to evolve into specific neuronal and glial lineages to become mesencephalic dopaminergic neurons [6–8], motor neurons [9–11], and oligodendrocytes [12]. ...
DECODING NEURONAL FIRING AND MODELING NEURAL
... a complex array of connections. Individual neurons express a large number of active conductances (Connors et al., 1982; Adams & Gavin, 1986; Llinás, 1988; McCormick, 1990; Hille, 1992) and exhibit a wide variety of dynamic behaviors on time scales ranging from milliseconds to many minutes (Llinás, ...
... a complex array of connections. Individual neurons express a large number of active conductances (Connors et al., 1982; Adams & Gavin, 1986; Llinás, 1988; McCormick, 1990; Hille, 1992) and exhibit a wide variety of dynamic behaviors on time scales ranging from milliseconds to many minutes (Llinás, ...
Zebrafish and motor control over the last decade
... identifying the cells and circuits in zebrafish. In vivo calcium imaging has allowed for the rapid identification of neurons active in a particular behavioral context (Brustein et al., 2003b; Cox and Fetcho, 1996; Fetcho and O'Malley, 1995; O'Malley et al., 1996; Ritter et al., 2001). The ability to ...
... identifying the cells and circuits in zebrafish. In vivo calcium imaging has allowed for the rapid identification of neurons active in a particular behavioral context (Brustein et al., 2003b; Cox and Fetcho, 1996; Fetcho and O'Malley, 1995; O'Malley et al., 1996; Ritter et al., 2001). The ability to ...
Alkaloids * Natural nitrogenous secondary metabolites from plants
... • They can either mimic or block the effects of neurotransmitters, or cause fluctuations in the normal levels of neurotransmitters. • This leads to numerous physiological and psychological effects Role of neurotransmitters: to transmit nerve impulses across the synapse (space) between neurons in bra ...
... • They can either mimic or block the effects of neurotransmitters, or cause fluctuations in the normal levels of neurotransmitters. • This leads to numerous physiological and psychological effects Role of neurotransmitters: to transmit nerve impulses across the synapse (space) between neurons in bra ...
Parthenogenetic dopamine neurons from primate embryonic stem
... midbrain substantia nigra (SN) that are lost in Parkinson’s disease. Parthenogenesis has attracted attention as an alternative way to derive pluripotent stem cell lines that does not involve the destruction of viable embryos. However, parthenogenetic cells lack paternal imprinting and disorders rela ...
... midbrain substantia nigra (SN) that are lost in Parkinson’s disease. Parthenogenesis has attracted attention as an alternative way to derive pluripotent stem cell lines that does not involve the destruction of viable embryos. However, parthenogenetic cells lack paternal imprinting and disorders rela ...
NSS214 - National Open University of Nigeria
... neurons. Association neurons are present to "associate" appropriate motor responses with sensory stimuli. The early embryo contains an embryonic tissue layer known as ectoderm, on its surface that will eventually form the epidermis of the skin and the nervous system. As development continues, a groo ...
... neurons. Association neurons are present to "associate" appropriate motor responses with sensory stimuli. The early embryo contains an embryonic tissue layer known as ectoderm, on its surface that will eventually form the epidermis of the skin and the nervous system. As development continues, a groo ...
100 The Molecular and Structural Basis of Amblyopia
... (1992) in which tetanic electrical stimulation of synapses was used to induce long-term depression (LTD) of synaptic transmission in brain slices (reviewed by Bear, 2003). Although it is now appreciated that there are many mechanisms for LTD in different brain regions, some of these are well conserv ...
... (1992) in which tetanic electrical stimulation of synapses was used to induce long-term depression (LTD) of synaptic transmission in brain slices (reviewed by Bear, 2003). Although it is now appreciated that there are many mechanisms for LTD in different brain regions, some of these are well conserv ...
Morris_2007_Macrosto..
... to represent the most primitive animals with a true central nervous system (Bullock and Horridge 1965; Hanstroem 1968). Morphological studies at the light and electron microscopic level have concluded that all flatworms exhibit a number of plesiomorphic characters, which could be directly inherited ...
... to represent the most primitive animals with a true central nervous system (Bullock and Horridge 1965; Hanstroem 1968). Morphological studies at the light and electron microscopic level have concluded that all flatworms exhibit a number of plesiomorphic characters, which could be directly inherited ...
Neurophysiology of Pain - International Pain School
... • Nociceptors are free nerve endings that respond to stimuli that can cause tissue damage or when tissue damage has taken place. • Present in membrane of free nerve endings are receptors (protein molecules) whose activity changes in the presence of painful stimuli. • (Note the use of the same term r ...
... • Nociceptors are free nerve endings that respond to stimuli that can cause tissue damage or when tissue damage has taken place. • Present in membrane of free nerve endings are receptors (protein molecules) whose activity changes in the presence of painful stimuli. • (Note the use of the same term r ...
extrasynaptic glutamate does not reach the postsynaptic density
... doi:10.1016/j.brainres.2004.03.023 ...
... doi:10.1016/j.brainres.2004.03.023 ...
MND Australia International Research Update
... Melatonin is a hormone that is most well known for its role in regulating the body’s biological clock, the sleep-wake cycle. Recent research has suggested that melatonin may also have an antioxidant effect and potentially plays a role in preventing programmed cell death. Yi Zhang and colleagues at H ...
... Melatonin is a hormone that is most well known for its role in regulating the body’s biological clock, the sleep-wake cycle. Recent research has suggested that melatonin may also have an antioxidant effect and potentially plays a role in preventing programmed cell death. Yi Zhang and colleagues at H ...
Signalling organelle for retrograde axonal transport of
... more likely that the neurotrophins stimulate retrograde transport of the activated Trks, bound to their cognate ligand, to transmit this information14 by delivering an activated receptor to the cell body.15 Neurotrophins have two types of receptor: the high-affinity Trk family of tyrosine kinase rec ...
... more likely that the neurotrophins stimulate retrograde transport of the activated Trks, bound to their cognate ligand, to transmit this information14 by delivering an activated receptor to the cell body.15 Neurotrophins have two types of receptor: the high-affinity Trk family of tyrosine kinase rec ...
The role of metabotropic glutamate receptors in Alzheimer`s disease
... their specific localization may affect intracellular signaling in each neuron and eventually determine not only the fate of those cells but the function of the central nervous system in specific pathological and physiological conditions. Selective degeneration of populations of vulnerable neurons in ...
... their specific localization may affect intracellular signaling in each neuron and eventually determine not only the fate of those cells but the function of the central nervous system in specific pathological and physiological conditions. Selective degeneration of populations of vulnerable neurons in ...
The Late Effects of Polio - Polio Outreach of Washington
... previously weakened or paralysed muscle and were able to discard braces or wheelchairs. This was not only because of hard work and exercise, but also because of a phenomenon called SPROUTING. It seems that the denervated or orphaned muscle fibres within the same muscle sent out a kind of chemical di ...
... previously weakened or paralysed muscle and were able to discard braces or wheelchairs. This was not only because of hard work and exercise, but also because of a phenomenon called SPROUTING. It seems that the denervated or orphaned muscle fibres within the same muscle sent out a kind of chemical di ...