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Brain Bark
Brain Bark

... abstract information like music, colors or shapes and to synthesize experiences by giving a quick, general sense of what is happening ...
news and views - Cortical Plasticity
news and views - Cortical Plasticity

... implies that most neighboring pairs of neurons should not be connected. This finding helps explain why many neighboring neurons do not connect with functional synapses even though they are so close that their axons and dendrites can touch4. This sparsity of connectivity has been shown before, for ex ...
Molecular heterogeneity of central synapses: afferent and target
Molecular heterogeneity of central synapses: afferent and target

... synapses onto these two types of target cell. Whereas CA1 pyramidal neurons undergo homosynaptic long-term potentiation (LTP) in response to high-frequency stimulation of CA3 afferents, interneurons exhibit long-term depression (LTD) of the activated and non-activated synapses with the same stimulat ...
FEATURE ARTICLE Summation of Unitary IPSPs
FEATURE ARTICLE Summation of Unitary IPSPs

... events sum slightly sublinearly when targeting closely located postsynaptic sites. Simultaneous activation of many co-aligned inputs might lead to more significant nonlinear interactions especially in compartments of relatively small diameter. The axon initial segment of pyramidal cells has a limite ...
Chapter 2: Communication Within the Nervous System
Chapter 2: Communication Within the Nervous System

... the usual order of the vision and audition chapters, because I came to understand that audition provides a friendlier context for introducing the basic principles of sensation and perception. The chapters on addiction, motivation, emotion, and sex follow the introduction to neurophysiology; this was ...
MOA slides - Epilepsy
MOA slides - Epilepsy

... • Mode of Action (MOA) of existing anti-epileptic drugs (AEDs) • Glutamate mediated Post Synaptic Excitation • MOA of Perampanel, a selective, non-competitive AMPA receptor antagonist ...
THE JOURNAL OF COMPARATIVE NEUROLOGY 460:80–93 (2003)
THE JOURNAL OF COMPARATIVE NEUROLOGY 460:80–93 (2003)

... cord to verify that CRNs project onto reticulospinal neurons. Electron microscopy of the labeled CRNs axons and terminals showed that even their most central and thinnest processes are myelinated. Most of the terminals are axodendritic, with multiple asymmetric synapses, and contain round vesicles ( ...
The Nervous System - Plain Local Schools
The Nervous System - Plain Local Schools

... • Neurons have the ability to conduct nerve impulses very quickly, but how does one cell communicate with another cell? • Adjacent neurons communicate by releasing chemicals across tiny gaps that separate them, called synapses (synaptic cleft) • The chemicals, known as neurotransmitters, are release ...
Lecture_29_noquiz
Lecture_29_noquiz

... The Goldman Equation extends the Nernst Equation to consider the relative permeabilities of the ions (P): Ions with higher P have a larger effect on Emembrane ...
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... synapses. Each of the 1012 neurons (1,000 billion, i.e. 1 trillion) has on average 7,000 synaptic connections to other neurons. It hast been estimated that the brain of a three-year-old child has about 1016 synapses (10,000 trillion). This number declines with age, stabilizing by adulthood. Estimate ...
These review questions are for the Bio 1 signal transduction topic
These review questions are for the Bio 1 signal transduction topic

... D) Each individual step can remove excess phosphate groups from the cytoplasm. E) Each step can be activated by several G proteins simultaneously. ...
Long Term Potentiation
Long Term Potentiation

... When long term potentiation occurs, in addition to an increase in AMPA receptor sites, there also appear to be permanent changes in the presynaptic neuron. The terminal buttons of the neurons involved in long term potentiation release more neurotransmitter after the potentiation has been created. Th ...
An octopaminergic system in the CNS of the snails, Lymnaea
An octopaminergic system in the CNS of the snails, Lymnaea

... All 3 OC cells are electrically coupled together and make the same synaptic effects on their followers. They interact with all the known buccal feeding motoneurons, and with all the buccal modulatory and central pattern generating interneurons. N1 (Protraction) phase: Motoneurons firing in this phas ...
Principles of patch-‐clamp electrical recording
Principles of patch-‐clamp electrical recording

... •  ChR2  ac4va4on  of  many  neurons  induces  an  “ar4ficial   synchroniza4on”  of  the  neural  network.   •  Changes  in  ionic  gradients  occur  when  using  light  gated  ion  pumps.   •  Non-­‐specific  targe4ng-­‐  leaky  expression  or ...
Lecture 5
Lecture 5

... epileptic seizures: wavelike electrical activity of a large number of neurons, often associated with loss of consciousness and involuntary body ...
Lecture 14 - School of Computing
Lecture 14 - School of Computing

... this encoding allows for graceful degradation so that even with 80% of data missing and many neurons deleted, sufficient information is present for classification purposes. The fact that only rate information was used suggests that temporal information is less important here. ...
The biology of time across different scales
The biology of time across different scales

... strength can act as a memory of what happened 100 ms ago. Because the network is in a different state the response to the stimulus will reflect the interval between the tones. A simple model of how short-term synaptic plasticity could allow neurons to respond selectively to specific intervals is sho ...
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1 - Test Bank wizard

... 1. In the structure of the neuron, the __________ sends information to other cells. a. axon b. dendrite c. soma d. myelin ANS: a LO=2.1 2. Which type of cell makes up 10 percent of the brain? a. glial cells b. neurons c. stem cells d. afferent cells ANS: b LO=2.1 3. Damaged nerve fibers in the body ...
Epilepsy and Seizure Disorders
Epilepsy and Seizure Disorders

... local connections Partial seizures spread into the other hemisphere via the corpus callosum Increase in extracellular K+ and accumulation of Ca2+ in presynaptic terminals also causes recruitment of more neurons  Type, number and distribution of voltage- and ligand-gated channels ...
Unit 3 Area of Study 1: How does the nervous system
Unit 3 Area of Study 1: How does the nervous system

... Parkinson’s disease ...
03/14 PPT
03/14 PPT

... Glomerular structure is a general feature of olfactory systems • Fruit flies have 60 different receptors • Neurons with the same receptor project to one glomerulus ...
Physiology Unit Objectives and Assignments
Physiology Unit Objectives and Assignments

... you could explain it to someone, mark the Green Light Box. If you kind of get it but still have some questions or need to a study a little more to memorize it, put an X in the Orange Light Box. If you do not understand the concept, have never heard of it, or are totally confused, put an X in the Red ...
Basic Structure and Function of Neurons
Basic Structure and Function of Neurons

... (7) The Role of Sensory Systems and Reflexes in Motor Function Some human behavior is innate and follows a stereotypic pattern, basically in all individuals. Examples of such behavior pattern are swallowing when taken by surprise. Centrals programs in the nervous system can coordinate the motoneuro ...
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... A pump which receives energy to make an exchange between sodium and potassium ions. This pump let two potassium ions in for each three sodium ions that leave the cell. ...
Vision
Vision

... Easily localized ...
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Neurotransmitter

Neurotransmitters are endogenous chemicals that enable neurotransmission. They transmit signals across a chemical synapse, such as in a neuromuscular junction, from one neuron (nerve cell) to another ""target"" neuron, muscle cell, or gland cell. Neurotransmitters are released from synaptic vesicles in synapses into the synaptic cleft, where they are received by receptors on other synapses. Many neurotransmitters are synthesized from simple and plentiful precursors such as amino acids, which are readily available from the diet and only require a small number of biosynthetic steps to convert them. Neurotransmitters play a major role in shaping everyday life and functions. Their exact numbers are unknown but more than 100 chemical messengers have been identified.
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