David Hunter Hubel. 27 February 1926 — 22 September 2013
... Subsequent work in the cat showed a continued modification of receptive field organization in the visual areas just beyond the primary visual cortex, and in at least one visual area beyond those. David and Torsten then largely switched to studying the monkey, first going back to the lateral genicula ...
... Subsequent work in the cat showed a continued modification of receptive field organization in the visual areas just beyond the primary visual cortex, and in at least one visual area beyond those. David and Torsten then largely switched to studying the monkey, first going back to the lateral genicula ...
2.1 central nervous system: neurotransmission and
... Duration 30sec-2min with impaired consciousness. CPS occurs when epileptic activity spreads to involve a major portion of the brain but does not become generalized. They often are preceded by aura and occur after a simple partial seizure particularly when it is of temporal lobe origin. CPS often beg ...
... Duration 30sec-2min with impaired consciousness. CPS occurs when epileptic activity spreads to involve a major portion of the brain but does not become generalized. They often are preceded by aura and occur after a simple partial seizure particularly when it is of temporal lobe origin. CPS often beg ...
Simulation of signal flow in 3D reconstructions of an anatomically
... neuronal cell types. The single neuron represents the elemental functional unit of these networks. Depending on their dendrite morphology, as well as their synaptic innervations and conductance distributions, neurons perform (non-) linear computations that generate a variety of electrical responses ...
... neuronal cell types. The single neuron represents the elemental functional unit of these networks. Depending on their dendrite morphology, as well as their synaptic innervations and conductance distributions, neurons perform (non-) linear computations that generate a variety of electrical responses ...
Cover page
... have further engineered the Ube3a transgene to permit neuron subtype and brain region specific increases of Ube3a gene dosage to enable circuit mapping of the autism-associated behavioral defects. A detailed analysis of circuit-specific changes in gene expression (ribotag) and physiology (optogeneti ...
... have further engineered the Ube3a transgene to permit neuron subtype and brain region specific increases of Ube3a gene dosage to enable circuit mapping of the autism-associated behavioral defects. A detailed analysis of circuit-specific changes in gene expression (ribotag) and physiology (optogeneti ...
Dopamine is one of major neurotransmitters in the brain
... retrograde labels will be injected into the different target regions of the mesolimbic and mesocortical pathways, the NA and the mPFC, respectively. The VTA will be subsequently visualized and cells and axons in the VTA will be checked for whether they are co-labeled or labeled with only one of the ...
... retrograde labels will be injected into the different target regions of the mesolimbic and mesocortical pathways, the NA and the mPFC, respectively. The VTA will be subsequently visualized and cells and axons in the VTA will be checked for whether they are co-labeled or labeled with only one of the ...
Hypothalamus and Limbic System
... responsible for showing that that the hypothalamus exerts control of the pituitary gland. • In the 1950s, Harris and colleagues carried out a series of transplantation experiments. – It had already been shown that endocrine glands (e.g. testes, ovaries, adrenal cortex) can function in a regulated ma ...
... responsible for showing that that the hypothalamus exerts control of the pituitary gland. • In the 1950s, Harris and colleagues carried out a series of transplantation experiments. – It had already been shown that endocrine glands (e.g. testes, ovaries, adrenal cortex) can function in a regulated ma ...
31 Relating the Activity of Sensory Neurons to Perception
... tasks to train animals to do. Nearly all psychophysical tasks with nonprimate subjects use detection tasks for this reason. ...
... tasks to train animals to do. Nearly all psychophysical tasks with nonprimate subjects use detection tasks for this reason. ...
Methamphetamine Users in Sustained Abstinence
... cover with prolonged abstinence.16,20-25 A series of positron emission tomography studies have tracked neuronal changes as a function of methamphetamine abstinence in human methamphetamine users. In 1 of the first positron emission tomography studies, McCann et al21 reported striatal dopamine trans ...
... cover with prolonged abstinence.16,20-25 A series of positron emission tomography studies have tracked neuronal changes as a function of methamphetamine abstinence in human methamphetamine users. In 1 of the first positron emission tomography studies, McCann et al21 reported striatal dopamine trans ...
A Candidate Pathway for a Visual Instructional Signal to the Barn
... important for the premotor control of head movements in response to auditory and visual stimuli (head saccades; du Lac and Knudsen, 1990). In respect to the issue of map alignment, this suggests that the instructive signal to the auditory space map is delivered by collaterals from neurons that inner ...
... important for the premotor control of head movements in response to auditory and visual stimuli (head saccades; du Lac and Knudsen, 1990). In respect to the issue of map alignment, this suggests that the instructive signal to the auditory space map is delivered by collaterals from neurons that inner ...
Hypothesized Deficiency of Guanine
... CSF. In view of this, lowered CSF HVA levels in Lesch-Nyhan syndrome implicate the basal ganglia in the emergence of at least some of the CNS symptoms (eg, choreoathetosis). Perhaps a diminished release of dopamine from terminals within basal ganglia leads to a compensatory up-regulation in the sens ...
... CSF. In view of this, lowered CSF HVA levels in Lesch-Nyhan syndrome implicate the basal ganglia in the emergence of at least some of the CNS symptoms (eg, choreoathetosis). Perhaps a diminished release of dopamine from terminals within basal ganglia leads to a compensatory up-regulation in the sens ...
BCM Theory
... Figure S2A. The signal triggers spikes in some IO cells that are in an upswing phase of their potential. An example of this upswing is shown in Figure S2B, where an external input (arrow in the figure) triggers a spike. Typically, when an IO neuron is in a downswing phase of its potential, the exter ...
... Figure S2A. The signal triggers spikes in some IO cells that are in an upswing phase of their potential. An example of this upswing is shown in Figure S2B, where an external input (arrow in the figure) triggers a spike. Typically, when an IO neuron is in a downswing phase of its potential, the exter ...
Molecular and anatomical signatures of sleep deprivation in the
... specific anatomic areas are differentially activated by SD. Imaging studies have shown differential enhancement or suppression of neural activity in specific cortical areas occurs during sleeping, waking, and SD (Nofzinger, 2005; Chee and Chuah, 2008). Specific anatomic areas also control the regula ...
... specific anatomic areas are differentially activated by SD. Imaging studies have shown differential enhancement or suppression of neural activity in specific cortical areas occurs during sleeping, waking, and SD (Nofzinger, 2005; Chee and Chuah, 2008). Specific anatomic areas also control the regula ...
Race modulates neural activity during imitation
... of race. Here we measured neural activity with fMRI while European American participants imitated meaningless gestures performed by actors of their own race, and two racial outgroups, African American, and Chinese American. Participants also passively observed the actions of these actors and their p ...
... of race. Here we measured neural activity with fMRI while European American participants imitated meaningless gestures performed by actors of their own race, and two racial outgroups, African American, and Chinese American. Participants also passively observed the actions of these actors and their p ...
Chapter 12 *Lecture PowerPoint Nervous Tissue
... – Identify the parts of a neuron. – Explain how neurons transport materials between the cell body and tips of the axon. ...
... – Identify the parts of a neuron. – Explain how neurons transport materials between the cell body and tips of the axon. ...
Identification of Mechanoafferent Neurons in Terrestrial Snail
... 䡠 䡠 䡠 , receptive field borders. Skin stripes pattern is shown for orientation. J Neurophysiol • VOL ...
... 䡠 䡠 䡠 , receptive field borders. Skin stripes pattern is shown for orientation. J Neurophysiol • VOL ...
Integrative neurobiology of energy homeostasis
... have been intensively studied (Fig. 1). Nevertheless, although the basic regulatory principles of the melanocortin pathway have been recognized over the last years, the complexity of the system still yields unexpected results. Thus, in contrast to the predicted important role for NPY and AgRP in ene ...
... have been intensively studied (Fig. 1). Nevertheless, although the basic regulatory principles of the melanocortin pathway have been recognized over the last years, the complexity of the system still yields unexpected results. Thus, in contrast to the predicted important role for NPY and AgRP in ene ...
17-Basal ganglion
... They are corpus striatum; amygdaloid nucleus and claustrum. Its major components are caudate nucleus; putamen and globus pallidus . These structures are involved in the control of posture and movement. They are sometimes referred to anatomically as the corpus striatum but clinically, as basal gangli ...
... They are corpus striatum; amygdaloid nucleus and claustrum. Its major components are caudate nucleus; putamen and globus pallidus . These structures are involved in the control of posture and movement. They are sometimes referred to anatomically as the corpus striatum but clinically, as basal gangli ...
Restraining influence of A2 neurons in chronic control of arterial
... Finally, notwithstanding the insights yielded from the aforementioned lesioning studies, any method that destroys neurons may lead to tissue necrosis, axonal sprouting and rewiring, compromising the integrity of the neuronal networks [18–20] and making data interpretation difficult. Our approach was ...
... Finally, notwithstanding the insights yielded from the aforementioned lesioning studies, any method that destroys neurons may lead to tissue necrosis, axonal sprouting and rewiring, compromising the integrity of the neuronal networks [18–20] and making data interpretation difficult. Our approach was ...
Neural Coding: Higher Order Temporal Patterns in the
... time- and context-dependent synchronization dynamics in different cortical areas. For interactions among more than two neurons, Gerstein, Perkel and Dayhoff (1985) devised the so called gravity method. Their method views neurons as particles that attract each other and measures simultaneously the at ...
... time- and context-dependent synchronization dynamics in different cortical areas. For interactions among more than two neurons, Gerstein, Perkel and Dayhoff (1985) devised the so called gravity method. Their method views neurons as particles that attract each other and measures simultaneously the at ...
CaseStudyBrain2016
... Directions: Based on the information provided indicate as much as you can about the location of the brain damage experienced by each of the following individuals (Note answers may vary but be sure to explain your proposals). All of the following case studies are based on real patients. Case Study #1 ...
... Directions: Based on the information provided indicate as much as you can about the location of the brain damage experienced by each of the following individuals (Note answers may vary but be sure to explain your proposals). All of the following case studies are based on real patients. Case Study #1 ...
Presentazione standard di PowerPoint
... appear to exist large tracts of bare axons and the length of the axonal initial segment was unexpectedly long. This does not fall in the "neuron doctrine". Fields (2) associates this anomaly to a possible amplification of connectivity. However, it is difficult to imagine that the fine and behavioura ...
... appear to exist large tracts of bare axons and the length of the axonal initial segment was unexpectedly long. This does not fall in the "neuron doctrine". Fields (2) associates this anomaly to a possible amplification of connectivity. However, it is difficult to imagine that the fine and behavioura ...
Brain Part
... Most basic functions (sensory & motor) are equally controlled by both left & right hemispheres (remember communication exists through corpus callosum). o However, for some association functions, one hemisphere has greater control over language-related activities including speech, writing, reading, m ...
... Most basic functions (sensory & motor) are equally controlled by both left & right hemispheres (remember communication exists through corpus callosum). o However, for some association functions, one hemisphere has greater control over language-related activities including speech, writing, reading, m ...
The Basal Ganglia and Chunking of Action Repertoires
... multiple input clusters from functionally related areas can overlap selectively and quite precisely. For example, inputs from the cortex of the hand representations of primary somatosensory (SI) areas 3b and 1, and of the primary motor (MI) hand cortex represention overlap with one another, whereas ...
... multiple input clusters from functionally related areas can overlap selectively and quite precisely. For example, inputs from the cortex of the hand representations of primary somatosensory (SI) areas 3b and 1, and of the primary motor (MI) hand cortex represention overlap with one another, whereas ...
interactions between number and space in parietal cortex
... Figure 1 | Behavioural studies showing numerical–spatial interactions. a | The spatial–numerical association of response codes (SNARC) effect. Participants are asked to judge whether a number is even or odd. Responses to larger numbers are faster on the right side of space whereas those for smaller ...
... Figure 1 | Behavioural studies showing numerical–spatial interactions. a | The spatial–numerical association of response codes (SNARC) effect. Participants are asked to judge whether a number is even or odd. Responses to larger numbers are faster on the right side of space whereas those for smaller ...