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No Slide Title - people.vcu.edu
No Slide Title - people.vcu.edu

... FROM THE MOTOR CORTEX CORTICOSPINAL PATHWAY CORTICOBULBAR PATHWAY PYRAMIDAL TRACT LATERAL CORTICOSPINAL TRACT ...
Neural Plasticity in Auditory Cortex
Neural Plasticity in Auditory Cortex

... the auditory cortex to sounds were affected not only by the physical sounds themselves, but also by the learned psychological or behavioral importance of acoustic stimuli. These findings clearly showed the error of the traditional belief that sensory cortices had purely sensory functions and were no ...
WHY HAVE MULTIPLE CORTICAL AREAS?
WHY HAVE MULTIPLE CORTICAL AREAS?

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review ecology and neurobiology of toxin avoidance and the
review ecology and neurobiology of toxin avoidance and the

... ionic bonds with numerous proteins, changing their conformation and impairing their function (Wink, 2003). Another broad category of defensive compounds interferes with specific aspects of herbivore physiology. Of central interest to us are those compounds that have evolved to interfere with signali ...
The neuronal ceroid lipofuscinoses: the same, but different?
The neuronal ceroid lipofuscinoses: the same, but different?

... event that leads to neuron loss, then what might be? Without a clear understanding of the normal function of any of the ‘CLN’ gene products, it has been difficult to determine the underlying disease mechanisms. As with other disorders, a whole variety of different possibilities have been suggested a ...
Communication as an emergent metaphor for neuronal operation
Communication as an emergent metaphor for neuronal operation

... Euclidean spaces and smooth mappings between them to be the most appropriate representations. In reality it is usually the case that objects are comparable only to some objects in the world, but not to all. In other words one cannot equip them with a ‘natural’ ordering relation. Representing objects ...
Supraspinal control of ejaculation
Supraspinal control of ejaculation

... Lesions of nucleus paragigantocellularis in medulla: as effective as spinal tran-section at releasing the urethrogenital reflex (model of orgasm) (Marson et al., ‘92). nPGi sends 5-HT axons to lower spinal cord; 5-HT lesions disinhibit UG reflex ...
Neurons, Hormones, and the Brain
Neurons, Hormones, and the Brain

... transmitted from one neuron to another; includes the axon terminal, synaptic cleft, and receptor sites on receiving cell.  Neurotransmitter: Chemical substance that is released by transmitting neuron at the synapse and alters the activity of the receiving neuron. ©2002 Prentice Hall ...
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... 12. Where is ornithine synthesized de novo when supplies run low?  Ornithine aminotransferase is in the intestine 13. How does arginine stimulate the urea cycle (2)?  Arginine increases the synthesis of NAG, which stimulates the action of carbamoyl phosphate synthetase i. Arginine levels will be e ...
The cutaneous sensory system Neuroscience and Biobehavioral
The cutaneous sensory system Neuroscience and Biobehavioral

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Neuroanatomy Handout #1: The Motor Neuron
Neuroanatomy Handout #1: The Motor Neuron

... • Local anesthetic drugs block sodium channels and therefore prevent action potentials from occurring. – Example: Novocain • General anesthetics open potassium channels wider than usual ...
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Lysinuric protein intolerance: one gene, many

... lysine plus citrulline supplementation to treat LPI unfortunately have remained inconclusive due to the small number of LPI patients (13). A breakthrough was achieved in 1999 with the identification of the LPI gene by two independent groups (1, 15). The transporter belongs to a larger family of hete ...
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Principle of Superposition-free Memory - Deep Blue
Principle of Superposition-free Memory - Deep Blue

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Amino acid catabolism I

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Chapter 103: Application Of Imaging Technologies In The

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The Evolution of Reentrance in the Vertebrate Brain
The Evolution of Reentrance in the Vertebrate Brain

... primordial origins) and is still involved with its original olfactory function. The hippocampus, by contrast, is a highly derived, multilayer structure (together with the dentate gyrus) which also exhibits an innovative biochemistry for long-term potentiation in mammals. Because of its connectivity, ...
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Neurodegenerative Diseases of Horses: Equine Motor Neuron

... because it constitutes between 30 and 50% of the total fatty acid content of the human brain (Young et al., 2005). Vitamin C is well-known for its antioxidant properties. Although it has not been as widely studied as vitamin E, several studies have examined their combined potential. N-acetylcysteine ...
Peroxisome Proliferator-Activated Receptors (PPARs)
Peroxisome Proliferator-Activated Receptors (PPARs)

... •  Leading to the expression of 2 PPARγ proteins: PPARγ-1 and PPARγ-2 •  The four PPARγ transcript variants are differentially expressed in human tissues and osteoblast cell lines. •  PPARγ-2 predominantly in adipocytes •  PPARγ-1 is ubiquitously expressed, including in osteoblasts •  Expressio ...
Brainstem 10
Brainstem 10

... The brain stem is connected with cerebellum through three pair of cerebellar peduncles. The brain stem is the site of cranial nuclei, the pathway of important ascending & descending tracts & the site of emergence of cranial nerves (from 3rd to 12th). Cranial nerves (with the exception of 4th) eme ...
HECTtype E3 ubiquitin ligases in nerve cell development and
HECTtype E3 ubiquitin ligases in nerve cell development and

... Based on their mode of action, two families of E3 ligases are distinguished, i.e. the Really Interesting New Gene (RING) and the Homologous to E6-AP C-terminus (HECT) type. Whereas RING type enzymes bring the ubiquitin-E2 complex into the molecular vicinity of the substrate and facilitate ubiquitin ...
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nervous system organization, 022817

... Much of the text material is from, “Principles of Anatomy and Physiology” by Gerald J. Tortora and Bryan Derrickson (2009, 2011, and 2014). I don’t claim authorship. Other sources are noted when they are used. The lecture slides are mapped to the three editions of the textbook based on the color-cod ...
Brains of Primitive Chordates - CIHR Research Group in Sensory
Brains of Primitive Chordates - CIHR Research Group in Sensory

... ganglia. Dorsal root ganglia and proximal cranial ganglia are derived from migratory neural crest in craniates; in cyclostomes, spinal dorsal root ganglia are generated by neural crest, whereas cranial ganglia derive from placodes. In contrast to their craniate counterparts, the dorsal root ganglion ...
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Clinical neurochemistry



Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.
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