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Origins, migration and differentiation of glial cells in
Origins, migration and differentiation of glial cells in

... placed in culture for an additional 24 hours of development and subsequently analyzed to determine the numbers and distributions of labelled progeny. The reliability of this technique for performing clonal analyses of embryonic cells has been previously described (Wetts and Fraser, 1988; Copenhaver ...
Neuronal sources of hedgehog modulate neurogenesis in the adult
Neuronal sources of hedgehog modulate neurogenesis in the adult

Subthalamic Stimulation-Induced Synaptic Responses in Substantia
Subthalamic Stimulation-Induced Synaptic Responses in Substantia

... the principal sources of excitatory glutamatergic input to dopaminergic neurons of the substantia nigra, yet stimulation of the STN produces both excitatory and inhibitory effects on nigral dopaminergic neurons recorded extracellularly in vivo. The present experiments were designed to determine the ...
PDF
PDF

... brightness/contrast and resolution (set at 600 ppi) with the aid of Adobe PhotoShop 6.0 software. To ascertain that postsynaptic structures contacted by human synaptophysin (ⴙ) terminals belonged to the host, rat motor neurons were identified by their morphology and size (>25 ␮m in soma diameter) and ...
Uygar Sümbül - Department of Statistics
Uygar Sümbül - Department of Statistics

... • Whole cell analysis of synapse distributions (with Prof. Liam Paninski and Prof. Franck Polleux) All excitatory and inhibitory synapses on the dendritic arbors of cortical pyramidal neurons are identified using structural and molecular information. Statistical methods are devised to analyze their ...
electrochemistry
electrochemistry

... exothermic reaction is normally lost as heat. However, it can be trapped and converted into electrical energy if the reactants involved are not in direct contact with each other. In galvanic cells redox reactions is split into two halfreactions, each occurring in two separate compartments, called ha ...
Electrochemistry
Electrochemistry

... Similarly the metals which are above hydrogen in electrochemical series can displace hydrogen from mineral acids. Cell Potential or EMF of a cell Every galvanic or voltaic cell is made up of two half-cells, the oxidation halfcell (anode) and the reduction half-cell (cathode). One of the electrodes m ...
Estimating Fast Neural Input Using Anatomical and
Estimating Fast Neural Input Using Anatomical and

... fast and slow chemical synapses, astrocytes, vasculatures, extracellular ions, ephaptic signals and gap junctions can be divided into a specific signal (blue, top) and a background signal (green, bottom). In this review article, we have focused on how to estimate the specific input from fast chemica ...
BACOFUN_2016 Meeting Booklet - Barrel Cortex Function 2016
BACOFUN_2016 Meeting Booklet - Barrel Cortex Function 2016

... Synaptic connectivity is one important constrain for cortical signal flow and function. Consequently, a complete synaptic connectivity map (i.e., connectome) of a cortical area across spatial scales would advance our understanding of cortex organization and function. We present a dense statistical c ...
PDF - Molecules and Cells
PDF - Molecules and Cells

... important for the function of ppk neurons, especially the subset of the ppk neurons that direct post-mating changes in egglaying. CG3542 encodes a protein predicted to regulate mRNA splicing, but this has not yet been confirmed. Since knock-down of CG3542 in ppk neurons affects egglaying but not re- ...
OPTOGENETIC STUDY OF THE PROJECTIONS FROM THE BED
OPTOGENETIC STUDY OF THE PROJECTIONS FROM THE BED

... cells that project to CeA. In thirteen of these cells, blue light stimuli elicited IPSPs (Fig. 2B1); ...
Corticothalamic feedback and sensory processing
Corticothalamic feedback and sensory processing

... role in egocentric selection in the visual and somatosensory systems is an open question, however, results from recent work in the visual system may support the idea of egocentric selection [17]. Although this line of thinking is certainly speculative, it represents a novel means for viewing cortic ...
Behavioral Detectability of Single-Cell Stimulation in the Ventral
Behavioral Detectability of Single-Cell Stimulation in the Ventral

... Analysis. We restricted the analysis of behavioral responses to those single-cell stimulation and catch trials in which animals were considered attentive, as judged by their performance in microstimulation trials. Specifically, singlecell stimulation trials and catch trials were included if the anim ...
PDF
PDF

... Neocortical pyramidal neurons have a spike initiation zone in the apical dendrite [10,11,12,14,19]. The dendritic spike generated in this location is composed of an initial fast component that has been shown to be mediated by voltage-sensitive Na+ channels followed by a slower Ca2+-dependent compone ...
Peripheric nervous system. Vegetative nervous system
Peripheric nervous system. Vegetative nervous system

... Silver impregnation. The specimen demonstrates nerve ganglia connected with each other by nerve fibres. The ganglia contains stellate neurous of dark-brown or black color surrounded by small glial cells and nerve fibres. Light areas seen among the ganglia represent loose connective tissue where this ...
Denes et al. 2007 - Philosophical Transactions of the Royal Society B
Denes et al. 2007 - Philosophical Transactions of the Royal Society B

... Our revised scenario, that the ancestral role of Bmp signalling was to promote sensory over motor neuron fates, rather than a general antineurogenic effect, fits well with the actual distribution of motor and sensory neurons in many invertebrates, where it appears to be the rule rather than the exce ...
A Cholinergic Mechanism for Reward Timing within Primary Visual Cortex Please share
A Cholinergic Mechanism for Reward Timing within Primary Visual Cortex Please share

... NIH Public Access Author Manuscript Neuron. Author manuscript; available in PMC 2014 February 20. ...
The Neurology of Posture
The Neurology of Posture

... how hard and rigid even tiny nerves can become. In that state they are practically impervious to stretch. Another — more profound — surprise was to discover that joints are often restricted, not from myofascial tension, but from neurofascial restriction. — from the fact that nerves, when they become ...
the giant serotonergic neuron of aplysia: a multi
the giant serotonergic neuron of aplysia: a multi

Spinal Sensorimotor System: An Overview
Spinal Sensorimotor System: An Overview

... network organization of the system. Think of Part I as a sort of “systems level over-view” of the topic. In it I will try to identify some key issues for EC-based network design. Spinal Cord Organization It’s probably no surprise that we should begin with the spinal cord itself, since this structure ...
Proper migration and axon outgrowth of zebrafish
Proper migration and axon outgrowth of zebrafish

... belonging to the immunoglobulin superfamily, have been shown to be crucial for nervous system development (Maness and Schachner, 2007). This has been demonstrated by countless in vitro assays, antibody perturbation assays as well as loss and gain of function experiments (Bingham et al., 2002). Due t ...
universidade federal do rio grande do norte instituto do
universidade federal do rio grande do norte instituto do

... questions opened a new field in biology: development. Until the 1880´s, observation and histology were the only available techniques limiting studies to be mainly descriptive. Even though a lot can be learned by these simple techniques, many rising questions could not be answered. By the end of the ...
Distribution and characterisation of Glucagon-like peptide
Distribution and characterisation of Glucagon-like peptide

... Here we detail the distribution of GLP-1R expressing cells throughout the mouse brain using a novel transgenic model, in which crerecombinase is expressed under the control of the Glp1r gene. We show that GLP-1R expression correlates well with that observed in the rat [14], non-human primates [15] a ...
Dopamine – CNS Pathways and Neurophysiology
Dopamine – CNS Pathways and Neurophysiology

... Intracellular recordings from identified DA neurons have provided important insights into the mechanisms underlying action potential generation in these neurons. Interestingly, DA neurons recorded from mesencephalic slices after severing of afferent processes continue to exhibit spontaneous activity ...
TOWARDS AN "EARLY NEURAL CIRCUIT SIMULATOR": A FPGA
TOWARDS AN "EARLY NEURAL CIRCUIT SIMULATOR": A FPGA

... according to the two-stage model of the nervous system. 2.2.1 First stage (trigeminal ganglion) model Each of the roughly 30 whiskers on the rat's face has associated with it between 1500 and 2000 ganglion neurons, If our dynamical state hypothesis is correct [6], these neurons must cover (in a pair ...
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Multielectrode array

Multielectrode arrays (MEAs) or microelectrode arrays are devices that contain multiple plates or shanks through which neural signals are obtained or delivered, essentially serving as neural interfaces that connect neurons to electronic circuitry. There are two general classes of MEAs: implantable MEAs, used in vivo, and non-implantable MEAs, used in vitro.
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