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Sample pages 2 PDF
Sample pages 2 PDF

... where R is the gas constant; T is the absolute temperature; F is Faraday’s constant; Pion is the permeability for potassium, sodium, and chloride ion, respectively; and [K], [N a], and [Cl] stand for the concentrations of the respective ions inside or outside of the cell. The Goldman-Hodgkin-Katz eq ...
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35-2 The Nervous System

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35-2 The Nervous System
35-2 The Nervous System

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video slide - Buena Park High School

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LESSON 2.3 WORKBOOK How fast do our neurons signal?
LESSON 2.3 WORKBOOK How fast do our neurons signal?

... This is not a great solution because the energy required to keep the Na+/K+ pump working to repolarize the axon membrane is huge. So axons have come up with another strategy, which is to have the action potential jump along the axon rather than progress down it (think of the action potential pogo-st ...
Synapses and Neurotransmitters
Synapses and Neurotransmitters

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... binds to the cell membrane. VGC’s do this when the voltage of the cell membrane goes from negative to positive. • The VGC’s which are inhibitory of an action potential are those that open K+ and Cl- channels. These ions both increase the negative voltage of the cell membrane, making farther away fro ...
Chapter 11 PowerPoint Slides PDF - CM
Chapter 11 PowerPoint Slides PDF - CM

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Potassium Currents Responsible for Inward and Outward
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... were injected intracellularly with biocytin at the end of the recording period. All of the injected neuronshad the characteristic morphological features of the spiny projection neurons, which have been describedin detail previously (Wilson and Groves, 1980; Kawaguchi et al., 1989, 1990) (Fig. 1A). T ...
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... Rationale: Astrocytes form scar tissue in brain that acts to impede the regrowth of nerve cells. 2.1-37. Myelination of brain nerve axon membranes is accomplished by a. oligodendrocytes. b. microglia. c. astrocytes. d. neurocytes. e. Schwann cells. Difficulty: 1 Question ID: 2.1-37 Page Ref: 37 Topi ...
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The Einstein-Podolsky-Rosen Paradox in the Brain
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... striking similarity between the transferred and evoked potentials and the total absence of transferred potentials in the control experiments leaves no room for doubt about the existence of an unusual phenomenon, namely, propagation of influence without local signals. As noted already, the similarity ...
FREE Sample Here
FREE Sample Here

... a. Neurons have a high metabolic rate. b. The dendrites store nutrients and oxygen for the neuron. c. Dead neurons are consumed by other neurons. d. Neurons make up 29% of the volume of the brain. e. Neurons can survive for hours without oxygen. Difficulty: 2 Question ID: 2.1-31 Page Ref: 35 Topic: ...
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Physiology of muscles and nerves
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nerve part 1
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... outside and a high concentration of K ion inside the nerve cells • Any condition decreases the metabolic activity of the cell e.g. by cooling →inhibits Na-K pump →Na+ ions will accumulate inside the cell and neutralize the -ve charges of protein ions and K ions that held on the outer surface escape ...
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... a. Neurons have a high metabolic rate. b. The dendrites store nutrients and oxygen for the neuron. c. Dead neurons are consumed by other neurons. d. Neurons make up 29% of the volume of the brain. e. Neurons can survive for hours without oxygen. Difficulty: 2 Question ID: 2.1-31 Page Ref: 35 Topic: ...
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Resting potential



The relatively static membrane potential of quiescent cells is called the resting membrane potential (or resting voltage), as opposed to the specific dynamic electrochemical phenomena called action potential and graded membrane potential.Apart from the latter two, which occur in excitable cells (neurons, muscles, and some secretory cells in glands), membrane voltage in the majority of non-excitable cells can also undergo changes in response to environmental or intracellular stimuli. In principle, there is no difference between resting membrane potential and dynamic voltage changes like action potential from a biophysical point of view: all these phenomena are caused by specific changes in membrane permeabilities for potassium, sodium, calcium, and chloride ions, which in turn result from concerted changes in functional activity of various ion channels, ion transporters, and exchangers. Conventionally, resting membrane potential can be defined as a relatively stable, ground value of transmembrane voltage in animal and plant cells.Any voltage is a difference in electric potential between two points—for example, the separation of positive and negative electric charges on opposite sides of a resistive barrier. The typical resting membrane potential of a cell arises from the separation of potassium ions from intracellular, relatively immobile anions across the membrane of the cell. Because the membrane permeability for potassium is much higher than that for other ions (disregarding voltage-gated channels at this stage), and because of the strong chemical gradient for potassium, potassium ions flow from the cytosol into the extracellular space carrying out positive charge, until their movement is balanced by build-up of negative charge on the inner surface of the membrane. Again, because of the high relative permeability for potassium, the resulting membrane potential is almost always close to the potassium reversal potential. But in order for this process to occur, a concentration gradient of potassium ions must first be set up. This work is done by the ion pumps/transporters and/or exchangers and generally is powered by ATP.In the case of the resting membrane potential across an animal cell's plasma membrane, potassium (and sodium) gradients are established by the Na+/K+-ATPase (sodium-potassium pump) which transports 2 potassium ions inside and 3 sodium ions outside at the cost of 1 ATP molecule. In other cases, for example, a membrane potential may be established by acidification of the inside of a membranous compartment (such as the proton pump that generates membrane potential across synaptic vesicle membranes).
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