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16 Myocardial Disease
16 Myocardial Disease

... dates back to Donald Teare in 1958 who reported a common finding of asymmetric hypertrophy in the hearts of nine victims of sudden death from six families. Histological assessment of the myocardium revealed muscle bundles in different orientations separated by connective tissue. This seminal case se ...
Function and mechanics of the left ventricle: from
Function and mechanics of the left ventricle: from

... function. The traditional measurement of ejection fraction is based upon tracing the left ventricular borders and calculating left ventricular volumes using geometric assumptions. Now, with the introduction of three-dimensional echocardiography, the evaluation of left ventricular function is easier ...
Basics of EKG Interpretation:
Basics of EKG Interpretation:

... See localized ECG changes and one can predict which artery is involved. Criteria for thrombolytic therapy = ST elevation in two electrically contiguous leads. Adjacent precordial leads are "contiguous." To figure out which limb leads are "electrically contiguous," use a hexaxial diagram. (The diagra ...
the ECG - HumanPhysiology.Academy
the ECG - HumanPhysiology.Academy

... the amplitude of the ECG signal depends on the speed and the strength of the electrical signal in the heart. Something that is very fast and excites a lot of tissue, will show a strong signal on the ECG. A good example of this is the QRS-complex because it represents fast depolarization of the thick ...
Basics of EKG Interpretation
Basics of EKG Interpretation

... See localized ECG changes and one can predict which artery is involved. Criteria for thrombolytic therapy = ST elevation in two electrically contiguous leads. Adjacent precordial leads are "contiguous." To figure out which limb leads are "electrically contiguous," use a hexaxial diagram. (The diagra ...
The Association between the Pattern of Premature Ventricular
The Association between the Pattern of Premature Ventricular

... right ventricle (LBBB pattern) in the absence of heart disease is not clear. According to a survey of asymptomatic, healthy subjects, the ratio of the LBBB pattern to the RBBB pattern is 3 to 111). It is possible that these LBBB pattern PVCs reflect abnormalities in the right ventricle and these abn ...
PDF
PDF

... was used: some dogs (6/16) were first exercise-tested under the influence of this β-adrenoceptor antagonist, and on a later day, had a control test (i.e., with no drug) performed; whereas in the remaining animals (10/16) the response to the submaximal exercise test (SMT) was first studied under cont ...
Manifest and Concealed Reentry
Manifest and Concealed Reentry

... findings in both man and experimental animals are in agreement with those of Moe and Mendez who stated that reciprocal responses can be so readily induced in normal animal hearts that their occurrence must be considered a normal physiologic response.10 This reentry can be either manifest or conceale ...
Seminars in Cardiothoracic and Vascular Anesthesia
Seminars in Cardiothoracic and Vascular Anesthesia

... control mechanisms. Etomidate causes the least cardiovascular depression. It is popular for induction of anesthesia in cardiac-compromised patients; however, it is not suitable for maintenance of anesthesia because it depresses adrenocortical function. Ketamine has a favorable cardiovascular profile ...
Flecainide Therapy Reduces Exercise
Flecainide Therapy Reduces Exercise

... de Cardiologie, Hôpital Lariboisière, Assistance Publique–Hôpitaux de Paris, Université Paris Diderot, INSERM U942, Paris, France; ††Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan; ‡‡Department of Pediatr ...
Chapter 3 The electrocardiogram
Chapter 3 The electrocardiogram

... Electrical discharges from these cells produce depolarization that spreads through the atrial muscle from right to left. The only route by which electrical activity can then reach the ventricles is via further specialized pacemaker cells; the atrioventricular node (AVN). From the AVN, electrical act ...
Seminars in Cardiothoracic and Vascular Anesthesia
Seminars in Cardiothoracic and Vascular Anesthesia

... control mechanisms. Etomidate causes the least cardiovascular depression. It is popular for induction of anesthesia in cardiac-compromised patients; however, it is not suitable for maintenance of anesthesia because it depresses adrenocortical function. Ketamine has a favorable cardiovascular profile ...
Cardiac Nurses Current Awareness Newsletter May 2016
Cardiac Nurses Current Awareness Newsletter May 2016

... Gordon M Saperia, MD, FACC Susan B Yeon, MD, JD, FACC Brian C Downey, MD, FACC Contributor disclosures All topics are updated as new evidence becomes available and our peer review process is complete. Literature review current through: Apr 2016. | This topic last updated: May 09, 2016. The following ...
Elevated circulating cardiotrophin-1 in heart failure
Elevated circulating cardiotrophin-1 in heart failure

... increased circulating plasma CT-1 levels in patients with heart failure is unknown. One possibility is that CT-1 expression may be induced by myocyte stretch. Indeed, mechanical stretch activates the JAK\STAT pathway and augments expression of CT-1 mRNA in rat cardiomyocytes [21]. It is intuitive to ...
natural causes of sudden death
natural causes of sudden death

... At the end of this lecture you should be able to:  Define sudden (natural) death  Classify the causes of sudden death  Discuss sudden cardiac death  Discuss the sudden infant death syndrome  Discuss the causes of sudden death in Jamaica The medicolegal term “sudden death” (sometimes called "sud ...
Rheology of discrete subaortic stenosis - Heart
Rheology of discrete subaortic stenosis - Heart

... A four stage aetiology for the development and progression of discrete subaortic stenosis has been proposed, based on Cape’s hypothesis.16 The procession of events begins with an underlying morphological abnormality, such as a steep aortoseptal angle, which is associated with a genetic predispositio ...
Feline Cardiomyopathy—Establishing a Diagnosis The Ohio
Feline Cardiomyopathy—Establishing a Diagnosis The Ohio

... primary cardiomyopathies (such as taurine deficiency in cats with DCM). The current accepted classification system for human myocardial disease acknowledges DCM, HCM, RCM, arrhythmogenic right ventricular cardiomyopathy (ARVC), and “unclassified” cardiomyopathies.2 This classification system has sup ...
An Approach to Analysis of Left Ventricular Diastolic Function and
An Approach to Analysis of Left Ventricular Diastolic Function and

... The sample volume is placed within the PV 1– 2 cm from its orifice. Color Doppler helps localize PV flow for optimal positioning of the PW Doppler sample box.22 Normal PV recording has a systolic profile, S-wave, which can be monophasic or biphasic (Fig. 4B). The first S-wave (S1) results from atria ...
Functional and Structural Differences in Atria Versus Ventricles in
Functional and Structural Differences in Atria Versus Ventricles in

... not only morphologically but also physiologically with different characteristic rates of contrac‐ tility [2]. Fish heart design is reflective of the needs for oxygen delivery to working skeletal muscle in an often oxygen poor environment. The heart is the first definitive organ to develop and become ...
Regional Oxygen Saturation of Small Arteries and Veins in the
Regional Oxygen Saturation of Small Arteries and Veins in the

... shown by polarography,2-:l by mass specrroscopy,4 by measurements of enzyme activity levels,5'" and in isolated hearts by microscopic oximetry of veins.7 If such differences do, in fact, exist, the ENDO could be less dependent on aerobic metabolism than the EPI for several reasons: diffusional loss ...
ASSOCIATION OF EARLY REPOLARIZATION WITH RISK OF CARDIAC MORTALITY IN
ASSOCIATION OF EARLY REPOLARIZATION WITH RISK OF CARDIAC MORTALITY IN

... studies. It was found the presence of a transmural electrical heterogeneity, which under certain conditions, such as the use of specific drugs and various levels of autonomic tone and electrolytes, could be dramatically amplified resulting in malignant arrhythmias (21). Case control studies A defini ...
Antiarrhythmic drugs for out-of-hospital cardiac arrest with
Antiarrhythmic drugs for out-of-hospital cardiac arrest with

... Out‐of‐hospital cardiac arrest (OHCA) affects approximately 300,000 people in the United States, 280,000 people in Europe and 110,000 people in Japan each year [1–3]. Among all the presentations of cardiac arrest (asystole, pulseless electrical activity [PEA], ventricular fibrillation [VF], and puls ...
the star™ biphasic waveform - AED Defibrillator, Buy AED
the star™ biphasic waveform - AED Defibrillator, Buy AED

... Cardiac Science's STAR Biphasic waveform technology provides optimized energy delivery by measuring a patient’s impedance and customizing a waveform to deliver the most effective defibrillation energy. This customization occurs for even the most difficult high-impedance patients. The STAR Biphasic t ...
Surgery for Atrial Fibrillation
Surgery for Atrial Fibrillation

... catheter ablation, and patients with intolerable symptoms or an impaired quality of life due to atrial fibrillation. The maze and radial procedures cure atrial fibrillation in the majority of patients, however, the procedures are not guided by electrophysiologic findings in individual patients, and ...
The normal and diseased pericardium: Current concepts of
The normal and diseased pericardium: Current concepts of

... are often only modestly increased) . Adrenergic stimulation also increases peripheral resistan ce to support decreasing arterial pressure, but a most important consequence is its inotropic effect. which impro ves the ejection fraction as a result of greater systolic emptying and therefore greater st ...
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Ventricular fibrillation



Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.
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