
Course Introduction: The Brain, chemistry, neural signaling
... Ions are electrically-charged molecules e.g. sodium (Na+), potassium (K+), chloride (Cl-). The resting potential exists because ions are concentrated on different sides of the membrane. Na+ and Cl- outside the cell. K+ and organic anions inside the cell. ...
... Ions are electrically-charged molecules e.g. sodium (Na+), potassium (K+), chloride (Cl-). The resting potential exists because ions are concentrated on different sides of the membrane. Na+ and Cl- outside the cell. K+ and organic anions inside the cell. ...
Nervous Tissue
... plasma membrane to any ion. Changing the concentration of ions across the plasma membrane. Depolarization - membrane potential decreases Hyperpolarization – membrane potential increases ...
... plasma membrane to any ion. Changing the concentration of ions across the plasma membrane. Depolarization - membrane potential decreases Hyperpolarization – membrane potential increases ...
Action Potential Web Quest
... 5. There are about ______________ neurons in the brain as well as ______________ of support cells called _____________________. 6. There are 3 major types of glial cells. Name each of the 3 and explain their function: ...
... 5. There are about ______________ neurons in the brain as well as ______________ of support cells called _____________________. 6. There are 3 major types of glial cells. Name each of the 3 and explain their function: ...
Lecture_30_2014
... • Excitatory synapses cause the post-synaptic cell to become less negative triggering an excitatory post-synaptic potential (EPSP) – Increases the likelihood of firing an action potential ...
... • Excitatory synapses cause the post-synaptic cell to become less negative triggering an excitatory post-synaptic potential (EPSP) – Increases the likelihood of firing an action potential ...
No Slide Title
... breaks down substances no longer required by the cell. • The plasma membrane separates the inside of the cell from the outside, it is selectively permeable with charged ions only able to pass through protein channels. ...
... breaks down substances no longer required by the cell. • The plasma membrane separates the inside of the cell from the outside, it is selectively permeable with charged ions only able to pass through protein channels. ...
Nervous and Immune Systems
... Taste, smell, solute concentration (osmoreceptors), glucose, oxygen, carbon dioxide Photoreceptors: receptors that respond to different wavelengths of light ...
... Taste, smell, solute concentration (osmoreceptors), glucose, oxygen, carbon dioxide Photoreceptors: receptors that respond to different wavelengths of light ...
Nervous System
... The faster the body can send out signals, the faster one can react. But how does the body increase the speed of conduction? The axon of some neurons is covered by Schwann cells. Since these cells are made from lipids, they are insulators. This causes the electrical signal to jump over the Schwan ...
... The faster the body can send out signals, the faster one can react. But how does the body increase the speed of conduction? The axon of some neurons is covered by Schwann cells. Since these cells are made from lipids, they are insulators. This causes the electrical signal to jump over the Schwan ...
Nervous Tissue - Chiropractor Manhattan | Chiropractor New
... cannot be initiated, even with a very strong stimulus. Relative refractory period – an action potential can be initiated, but only with a larger than normal stimulus. ...
... cannot be initiated, even with a very strong stimulus. Relative refractory period – an action potential can be initiated, but only with a larger than normal stimulus. ...
Class Notes 2
... Protoplasmic streaming is produced by actinomyosin as found in animal muscle. Streaming is inhibited when Ca++ moves into the cytoplasm activating a protein kinase that phosphorylates myosin so it can’t bind with actin. ...
... Protoplasmic streaming is produced by actinomyosin as found in animal muscle. Streaming is inhibited when Ca++ moves into the cytoplasm activating a protein kinase that phosphorylates myosin so it can’t bind with actin. ...
Action Potential
... Components of an Action Potential 1. Threshold: Minimum strength of current required 2. All or none phenomena: - Either a complete action potential that propagates along the axon or no response at all - once generated, moves along the axon without a drop or gain in amplitude 3. Always followed by a ...
... Components of an Action Potential 1. Threshold: Minimum strength of current required 2. All or none phenomena: - Either a complete action potential that propagates along the axon or no response at all - once generated, moves along the axon without a drop or gain in amplitude 3. Always followed by a ...
Cell and Molecular Biology 5/e
... Cardiac glycosides: plant and animal steroids Ouabain! Digitalis!: increased Na+ conc inside heart leads to stimulation of Na+Ca2+ exchanger, which extrudes sodium in exchange for inward movement of calcium. Increased intracellular Calcium stimulates muscle contraction. ...
... Cardiac glycosides: plant and animal steroids Ouabain! Digitalis!: increased Na+ conc inside heart leads to stimulation of Na+Ca2+ exchanger, which extrudes sodium in exchange for inward movement of calcium. Increased intracellular Calcium stimulates muscle contraction. ...
chapter 8 neuronal physiology A
... membrane potential • Concentration gradient of ions across the membrane • Membrane permeability to ions (channels) • If these change, the membrane potential changes ...
... membrane potential • Concentration gradient of ions across the membrane • Membrane permeability to ions (channels) • If these change, the membrane potential changes ...
Epilepsy & Membrane Potentials
... Functional Organization of Nervous System Central Nervous System ...
... Functional Organization of Nervous System Central Nervous System ...
Lecture 02
... “white matter” of the brain (grey matter are somas and dendrites). This speeds transmission, because the spike jumps between the gaps (nodes of Ranvier) and the sheath provides electrical insulation. In each gap, the original amplitude is restored, so it’s stays the same. ...
... “white matter” of the brain (grey matter are somas and dendrites). This speeds transmission, because the spike jumps between the gaps (nodes of Ranvier) and the sheath provides electrical insulation. In each gap, the original amplitude is restored, so it’s stays the same. ...
Midterm Review Answers
... 2) Tetraethylammonium (TEA) prevents the action potential from being produced. (T/F) 3) Radioactive TTX is commonly used to determine the density and distribution of voltage dependent Na+ channels. What would you expect the pattern of TTX labeling to be in a … a) myelinated axon TTX labeling would b ...
... 2) Tetraethylammonium (TEA) prevents the action potential from being produced. (T/F) 3) Radioactive TTX is commonly used to determine the density and distribution of voltage dependent Na+ channels. What would you expect the pattern of TTX labeling to be in a … a) myelinated axon TTX labeling would b ...
of the moving action potential. - Lectures For UG-5
... no matter how strong until they pass through their “closed and not capable of opening” conformation and they are reset to their “closed and capable of opening” conformation • Absolute refractory period lasts the entire time from threshold to depolarization peak and to hyperpolarization peak ...
... no matter how strong until they pass through their “closed and not capable of opening” conformation and they are reset to their “closed and capable of opening” conformation • Absolute refractory period lasts the entire time from threshold to depolarization peak and to hyperpolarization peak ...
4.BiologicalPsycholo..
... FIGURE 2.2 Electrical probes placed inside and outside an axon measure its activity. (The scale is exaggerated here. Such measurements require ultra-small electrodes, as described later in this chapter.) The inside of an axon at rest is about -60 to -70 millivolts, compared with the outside. Electro ...
... FIGURE 2.2 Electrical probes placed inside and outside an axon measure its activity. (The scale is exaggerated here. Such measurements require ultra-small electrodes, as described later in this chapter.) The inside of an axon at rest is about -60 to -70 millivolts, compared with the outside. Electro ...
Nervous Tissue
... – Inside (+) ions move from stimuli site to neighboring () areas – Outside (+) ions move toward stimuli site ...
... – Inside (+) ions move from stimuli site to neighboring () areas – Outside (+) ions move toward stimuli site ...
Slide 1
... Buffer and maintain potassium ion concentrations Guide migration of neurons during development ...
... Buffer and maintain potassium ion concentrations Guide migration of neurons during development ...
Nervous System Notes
... amplitude, action potentials are all-or-none 2. Duration – graded potentials are much longer (several milliseconds to several minutes) than action potentials (1/2 to 2 milliseconds) 3. Channels – graded use chemically, mechanically and light gated ion channels, action potentials use voltage gated ch ...
... amplitude, action potentials are all-or-none 2. Duration – graded potentials are much longer (several milliseconds to several minutes) than action potentials (1/2 to 2 milliseconds) 3. Channels – graded use chemically, mechanically and light gated ion channels, action potentials use voltage gated ch ...
Generation and propagation of axon potentials
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl−) with a negative charge. There are also potassium (K+) ions. ...
... In water, the salt NaCl molecule breaks down, and we get charged atoms, called ions: Natrium with a positive charge (Na+) , and chlorine (Cl−) with a negative charge. There are also potassium (K+) ions. ...
This guided reading is a hybrid of two chapters: chapter 40, section
... Label the figure. Include the synaptic vesicle, synaptic cleft, neurotransmitters, voltage-gated calcium ion channel, presynaptic membrane, postsynaptic membrane, ligand-gated ion channels, and synapse. [2] ...
... Label the figure. Include the synaptic vesicle, synaptic cleft, neurotransmitters, voltage-gated calcium ion channel, presynaptic membrane, postsynaptic membrane, ligand-gated ion channels, and synapse. [2] ...
Myers Module Four
... Neuron stimulation causes a brief change in electrical charge. If strong enough, this produces depolarization and an action potential. This depolarization produces another action potential a little farther along the axon. Gates in this neighbouring area are now open, and sodium ions rush in. The sod ...
... Neuron stimulation causes a brief change in electrical charge. If strong enough, this produces depolarization and an action potential. This depolarization produces another action potential a little farther along the axon. Gates in this neighbouring area are now open, and sodium ions rush in. The sod ...
Neural Modeling
... Numerical solution for f(v,w) = v(v-a)(1-v) -w and g(v,w) = v-bw with =0.01, a =0.1, b =0.5. The equations have a unique globally stable steady state at the origin. If v is perturbed slightly from the stead state, the system returns there immediately, but if it is perturbed beyond v = h2(0) = 0.1, ...
... Numerical solution for f(v,w) = v(v-a)(1-v) -w and g(v,w) = v-bw with =0.01, a =0.1, b =0.5. The equations have a unique globally stable steady state at the origin. If v is perturbed slightly from the stead state, the system returns there immediately, but if it is perturbed beyond v = h2(0) = 0.1, ...
Action potential

In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as ""nerve impulses"" or ""spikes"", and the temporal sequence of action potentials generated by a neuron is called its ""spike train"". A neuron that emits an action potential is often said to ""fire"".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (in response to depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and then they are actively transported back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This mechanism prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a ""primer"" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.