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Nervous System - De Anza College
Nervous System - De Anza College

... long distance – electrical signals ...
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... • The membrane is selectively permeable, allowing some chemicals to pass more freely than others. • Sodium, potassium, calcium, and chloride pass through channels in the membrane. • When the membrane is at rest: • Sodium channels are closed. • Potassium channels are partially closed. ‫رافع عاوي الفي ...
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... abundance of + charges compared to inside. The inside of the membrane is negative compared to the outside. This is helped by the (-) proteins etc. The “sodium-potassium” pump pulls 2 K+ ions in for 3 Na+ ions sent out. This further creates a charge difference!! ...
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Action Potential

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Summary Sodium pump.
Summary Sodium pump.

... of the vesicles to move to the end of the axon and discharge their contents into the synaptic cleft. Released neurotransmitters diffuse across the cleft, and bind to receptors on the other cell's membrane, causing ion channels on that cell to open. Some neurotransmitters cause an action potential, o ...
File
File

... A neuron may receive many excitatory and inhibitory signals since its dendrites and cell body can have synapses with many other neurons. • Excitatory signals: cause a depolarizing effect • Inhibitory signals: cause a hyperpolarizing effect Synaptic integration is the summing up of the excitatory and ...
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chapter 3 cells of the nervous system

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a positive electrical signal
a positive electrical signal

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Nervous Systems - Groupfusion.net
Nervous Systems - Groupfusion.net

... • Neurons are excitable cells – a stimulus can change the neuron’s membrane potential • Resting potential – membrane potential of unexcited neuron (-70mV) • Neurons become “excited,” when a stimulus opens a gated ion channel and increases the movement of K+ or Na+ across the plasma membrane ...
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Q1 (from chapter 1)

... A. Lobotomy causes drastic changes in personality and comportment B. Major motor and sensory pathways cross sides C. Bilateral hippocampectomy causes global aphasia D. In most people the left hemisphere is dominant for language abilities E. Orbitofrontal cortex is responsible for social behavior Q2 ...
action potential
action potential

... Schwann cells = specialized lipid-rich cells that form a myelin sheath by wrapping in a spiral pattern around a single axon. ...
Nervous Systems
Nervous Systems

... • Neurons are excitable cells – a stimulus can change the neuron’s membrane potential • Resting potential – membrane potential of unexcited neuron (-70mV) • Neurons become “excited,” when a stimulus opens a gated ion channel and increases the movement of K+ or Na+ across the plasma membrane ...
reading guide
reading guide

... Figure 48.10 contains almost all you need to know about nerve impulse transmission, so it is worth some careful study time. Let’s approach it in steps. a. Label Na+, K+, and their respective ion channels. b. Label the Resting state figure. Are the Na+ and K+ channels open, or closed? c. Label Depola ...
Action Potential
Action Potential

... Saltatory Conduction: myelinated portions of the axon that lack voltage gated channels can cause loss of current!  This problem is solved because some neurons are not myelinated all the way down. There are areas between myelinated parts that are called Nodes of Ranvier- rich in voltage channels whe ...
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Action potential



In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as ""nerve impulses"" or ""spikes"", and the temporal sequence of action potentials generated by a neuron is called its ""spike train"". A neuron that emits an action potential is often said to ""fire"".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (in response to depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and then they are actively transported back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This mechanism prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a ""primer"" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.
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