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Basal Ganglia: Internal Organization
Basal Ganglia: Internal Organization

... (see below). The corticostriatal and thalamostriatal projections are highly topographically organized and impart functionality onto the striatum and, consequently, other divisions of the basal ganglia. The main synaptic targets of the cortical and thalamic inputs to the basal ganglia are the medium- ...
neural_networks
neural_networks

... 2. Variables whose values the simulation generates In the first case: we parameterize the computational elements In the second case: variables are continuously changed at successive time steps by the computational steps of the simulation. Parameterized variables that we choose for each postsynaptic ...
Dual single unit recording in Globus Pallidus (GP) and Subthalamic
Dual single unit recording in Globus Pallidus (GP) and Subthalamic

... relationship between the two nuclei. A. An in-phase relationship is represented by firing rates that change in the same direction (increase or decrease) in both GP and STN. B An out-ofphase relationship is represented by firing rates that change in the opposite direction in GP and STN. ...
A computational account for the ontogeny of mirror neurons via
A computational account for the ontogeny of mirror neurons via

... In the early 1990s, mirror neurons were discovered in the ventral premotor cortex of the macaque monkey (Di Pellegrino et al., 1992). These neurons fired both when the monkeys grabbed an object and when they watched another primate grab that same object. Mirror neuron-like activity has been observed ...
Autonomic Nervous System
Autonomic Nervous System

... where they synapse with the dendrites of motor neurons. ...
Striate cortex increases contrast gain of macaque LGN neurons
Striate cortex increases contrast gain of macaque LGN neurons

lecture 12 - McLoon Lab - University of Minnesota
lecture 12 - McLoon Lab - University of Minnesota

The concept of a reflex
The concept of a reflex

... before additional injury can occur. To help an organism avoid injury reflex arcs provide a means for immediate withdrawal from dangerous stimuli. While all sensory information does eventually get sent to the brain for analysis, the advantage of a reflex arc is that it can process the rapid, protecti ...
A Point Process Model for Auditory Neurons Considering
A Point Process Model for Auditory Neurons Considering

... function. The Volterra expansion models the neuron’s baseline spike rate, its intrinsic dynamics spiking history - and the stimulus effect which in this case is the analog of the spectro-temporal receptive field (STRF). We performed the model fitting efficiently in a generalized linear model framewo ...
Can regenerating axons recapitulate developmental
Can regenerating axons recapitulate developmental

... @yale.edu doi:10.1038/nrn1957 ...
Document
Document

article in press - Neurobiology of Vocal Communication
article in press - Neurobiology of Vocal Communication

... suggesting that the PAG is not just a through-station of a descending vocalization pathway, but represents a relay station in which processing of vocal information takes place. Finally, single-unit recording studies have shown that the PAG contains neurons the activity of which is correlated with vo ...
Increased responses in trigeminocervical nociceptive neurons to cervical input after
Increased responses in trigeminocervical nociceptive neurons to cervical input after

... attributed to a sensitization of central nociceptive neurons with an increased excitability to afferent input. We investigated if noxious dural stimulation evokes sensitization of second-order neurons that leads to an increased responsiveness to stimulation of cervical afferents. Recordings were mad ...
Chapter 8 The Nervous System
Chapter 8 The Nervous System

“The swallow is a reflex” The phrase “the swallow is a reflex” may
“The swallow is a reflex” The phrase “the swallow is a reflex” may

... Various studies have been conducted utilizing positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to evaluate and document the extent of cortical involvement in swallowing. Cortical involvement has been identified in studies evaluating volitional control of swallowing ...
Behavioral flexibility is increased by optogenetic inhibition of
Behavioral flexibility is increased by optogenetic inhibition of

... bar-pressing task requiring a win– stay/lose –shift strategy. We found that optogenetic inhibition during action selection in the time segment preceding a lever press had no effect on performance. However, inhibition occurring in the time segment during feedback of results—whether rewards or nonrewa ...
Synaptic inhibition is caused by:
Synaptic inhibition is caused by:

... c. the width of the synaptic cleft d. the speed of impulse conduction down the pre-synaptic neurons e. cerebellar interactions with the caudate nuclei, mediated by the insula and the mammillary body ...
The Somatosensory System: Receptors and Central Pathways
The Somatosensory System: Receptors and Central Pathways

Neural Coding and Auditory Perception
Neural Coding and Auditory Perception

PDF
PDF

... Recurrent excitation can be potentially detrimental in leading to hyper-excitation of the circuit; inhibition is therefore required to modulate this excitation. Within all layers, excitatory and inhibitory neurons form recurrent connections. Between cortical layers, information flow has a strong dir ...
Cell-Type Specific Properties of Pyramidal
Cell-Type Specific Properties of Pyramidal

... correlating parameters from individual studies. The identification of genetically labeled neurons throughout the neocortex enabled in the present work the combined study of many parameters and their dependency on the sensory modality. We have characterized 2 populations of L5 pyramidal neurons geneti ...
Theroleofdendritesinauditory coincidence detection
Theroleofdendritesinauditory coincidence detection

Purves chs. 15, 19 - Weizmann Institute of Science
Purves chs. 15, 19 - Weizmann Institute of Science

Rhythmicity, randomness and synchrony in climbing fiber signals
Rhythmicity, randomness and synchrony in climbing fiber signals

... nuclear loop is essential for developing or enhancing these involuntary rhythmic movements. Thus, it could be that the rhythmic activity is controlled within the olivo– cerebello–nuclear loop in normal conditions. LTD at climbing fiber–Purkinje cell synapses [35–37] is a good candidate for mediating ...
e. Nervous System - 2404 copy
e. Nervous System - 2404 copy

... 4. the neurotransmitter is then either broken down or reabsorbed by the axon terminal ...
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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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