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The Thalamic Projections of the Spinothalamic Tract
The Thalamic Projections of the Spinothalamic Tract

... In subsequent years, research showed that input from lemniscal and spinothalamic systems reached different cell types in the thalamus, even in nuclei where they converged anatomically. Thus, in the VPL/VPM nuclei, medial lemniscal neurons projected to large and medium-sized cells that were immunoreac ...
Aalborg Universitet Assessment of sensory convergence in the spinal cord
Aalborg Universitet Assessment of sensory convergence in the spinal cord

... usually subdivided into the principal sensory nucleus and the spinal tract nucleus, which is further divided into the oralis, interpolaris, and caudalis subnuclei. The most caudal of these, the subnucleus caudalis (Vc), resembles the laminated structure and function of the spinal cord DH, and is for ...
Oxytocin Influence on the Nucleus of the Solitary Tract
Oxytocin Influence on the Nucleus of the Solitary Tract

... NTS neurons and heterogeneous innervation by oxytocin-containing axons projecting from the paraventricular nucleus. The study includes a brief, but interesting, discussion of how innervation of the NTS by oxytocin-synthesizing paraventricular nucleus neurons may modulate homeostatic reflexes; we pro ...
A Physiologically Plausible Model of Action Selection
A Physiologically Plausible Model of Action Selection

Effect of Methamphetamine Neurotoxicity on Learning- Arc Efferent Neurons
Effect of Methamphetamine Neurotoxicity on Learning- Arc Efferent Neurons

... neurons in the striatum (Kemp and Powell, 1971). Approximately half of these neurons, the striatonigral or "direct" pathway neurons, contain substance P and its preprotachykinin (PPT) precursor mRNA (Powell et al., 1973). The other half, the striatopallidal or "indirect" pathway neurons, contain met ...
Antennal Mechanosensory Neurons Mediate Wing Motor Reflexes
Antennal Mechanosensory Neurons Mediate Wing Motor Reflexes

... the subset of these neurons that are driven by the JO-AB or JO-CE GAL4 driver. This intersectional strategy has been used successfully in a previous study to genetically ablate JO neurons (Yorozu et al., 2009). To further validate the selective expression of ricin A and the lack of leaky expression ...
12 - PHSchool.com
12 - PHSchool.com

... With a structural map emerging, early neurologists were eager to localize functional regions of the cortex as well. Modern imaging techniques allow us to see the brain in action—PET scans show maximal metabolic activity in the brain, and functional MRI scans reveal blood flow (Figure 12.7). They hav ...
Where do mirror neurons come from?
Where do mirror neurons come from?

... explanation for the differences between monkeys and humans that have led some researchers to question the existence of a ‘mirror neuron system’. Second, it is consistent with evidence indicating that mirror neurons contribute to a range of social cognitive functions, but do not play a dominant, spec ...
Introduction
Introduction

... these postmitotic cells.9, 11 XIAP is a member of a family of Inhibitor of Apoptosis Proteins (IAPs) that have been shown to regulate caspases by directly binding to and inhibiting their function.12 Whereas cytosolic microinjection of cytochrome c is insufficient to induce apoptosis in wildtype neu ...
Document
Document

- D-Scholarship@Pitt
- D-Scholarship@Pitt

... (Kasthuri and Lichtman, 2003). Indeed, axon branches of motor neurons in which production of neurotransmitter is genetically reduced had a clear disadvantage in the competition and, perhaps as a result of this, became eliminated (Buffelli et al., 2003). These findings provide compelling evidence tha ...
Effective connectivity of the subthalamic nucleus
Effective connectivity of the subthalamic nucleus

... the basal ganglia including the output nuclei, subthalamic nucleus (STN), external globus pallidus (GP) and striatum, as well as in the cortex (Sharott et al. 2005; Mallet et al. 2008a,b; Degos et al. 2009; Avila et al. 2010; Moran et al. 2011). The appearance of such rhythms after chronic dopamine ...
Deficits of brainstem and spinal cord functions after
Deficits of brainstem and spinal cord functions after

... Deficits of brainstem and spinal cord functions after neonatal hypoxia–ischemia in mice Blandine Bellot1,2, Julie Peyronnet-Roux1, Catherine Gire2, Umberto Simeoni2,3, Laurent Vinay1 and Jean-Charles Viemari1 Background: Perinatal cerebral hypoxia–ischemia (HI) can lead to severe neurodevelopmental ...
Neuronal activity (c-Fos) delineating interactions of the cerebral
Neuronal activity (c-Fos) delineating interactions of the cerebral

Basal ganglia contributions to motor control: a - Research
Basal ganglia contributions to motor control: a - Research

... projects to the frontal cortex including parts of the premotor and primary motor cortex. (b) Internal connectivity of the BG motor circuit (front subpanel) showing principal pathways only. Direct and indirect pathways start in projection neurons of the putamen (part of the striatum) that express D1- ...
Spinal Cord Neural Modeling for Clinical Applications
Spinal Cord Neural Modeling for Clinical Applications

... Jeffrey Arle, M.D., Ph.D. (Board-certified, fellowship-trained neurosurgeon and Associate Chief of Neurosurgery at Beth Israel Deaconess Medical Center) was responsible for initiating, leading, and supervising this research. He conceived and wrote the original version of the neural simulation softwa ...
Kalirin, a Multifunctional Rho Guanine Nucleotide Exchange Factor
Kalirin, a Multifunctional Rho Guanine Nucleotide Exchange Factor

... Kalirin was first identified by its interaction with peptidylglycine ␣-amidating monooxygenase (PAM), an enzyme essential for neuropeptide biosynthesis (Alam et al., 1996). In addition to its two GEF domains, Kalirin has a kinase domain and several protein–protein interaction domains (Fig. 1 A). Alt ...
elaboration, remodeling and spatial organization of
elaboration, remodeling and spatial organization of

... centers, including the MBs and the lateral horns. Interestingly, individual PNs acquire distinct but invariant axon arborization patterns in the lateral horn, supporting the presence of an odor map in the higher brain center (Marin et al., 2002; Wong et al., 2002). Although variations exist in the p ...
Central circuitries for body temperature regulation and fever
Central circuitries for body temperature regulation and fever

Decoding a Temporal Population Code
Decoding a Temporal Population Code

Behavioral and Pathological Effects in the Rat
Behavioral and Pathological Effects in the Rat

... Before testing and dosing, the animals in this set were trained for the vertical ladder task (see below). The rats were then assigned to one of five groups, and dosed i.p. for 3 consecutive days with control vehicle (3 rats received 1 ml kg1 day1 of corn oil and 4 rats received 2 ml kg1 day1 of ...
Rebound spiking properties of mouse medial entorhinal cortex neurons in vivo NEUROSYSTEMS
Rebound spiking properties of mouse medial entorhinal cortex neurons in vivo NEUROSYSTEMS

... et al., 2012). Thus, inhibitory input to MEC cells may elicit subsequent spikes due to rebound depolarizations that cause rebound spikes. Rebound spikes may be integrated into a mechanism for generating theta cycle skipping (Jeffery et al., 1995; Brandon et al., 2013) and grid cell activity as demon ...
Hello. I`m Michael Farries, a graduate student of David Perkel. I have
Hello. I`m Michael Farries, a graduate student of David Perkel. I have

... globus pallidus/GPe, entopeduclular nucleus/GPi, ventral pallidum). There are some differences, of course, as one must expect for lineages that have been separate for 300 million years. For example, the avian pallidum (PP) doesn’t seem to be divided into internal and external segments as it is in ma ...
Role of Cerebral Cortex in Voluntary Movements
Role of Cerebral Cortex in Voluntary Movements

... Findings from studies using electrical stimulation of cortex, recording from single neurons in awake animals, and measuring regional cerebral blood flow in humans have revealed some specific motor functions for several cerebral cortical areas. These areas include primary motor cortex, supplementary ...
Structure-function relationship in hierarchical model of brain networks
Structure-function relationship in hierarchical model of brain networks

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Central pattern generator

Central pattern generators (CPGs) are biological neural networks that produce rhythmic patterned outputs without sensory feedback. CPGs have been shown to produce rhythmic outputs resembling normal ""rhythmic motor pattern production"" even in isolation from motor and sensory feedback from limbs and other muscle targets. To be classified as a rhythmic generator, a CPG requires:1. ""two or more processes that interact such that each process sequentially increases and decreases, and 2. that, as a result of this interaction, the system repeatedly returns to its starting condition.
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