Infographic: Carbapenemase
... LAST TEN YEARS. THE EMERGENCE OF CARBAPENEMASE-PRODUCING BACTERIA IS OF PARTICULAR CONCERN AS IT LEAVES VERY FEW THERAPEUTIC OPTIONS FOR INFECTIONS WITH THESE TYPES OF BACTERIA. ...
... LAST TEN YEARS. THE EMERGENCE OF CARBAPENEMASE-PRODUCING BACTERIA IS OF PARTICULAR CONCERN AS IT LEAVES VERY FEW THERAPEUTIC OPTIONS FOR INFECTIONS WITH THESE TYPES OF BACTERIA. ...
Lecture 3.Prokaryotes
... Prokaryotes have no membrane-bound nucleus or organelles – their DNA and some proteins are localized in the cytoplasm They vary in how their cell membrane is protected – some species have specialized surface structures that protect them from their environment or that enable them to move Prokaryotes ...
... Prokaryotes have no membrane-bound nucleus or organelles – their DNA and some proteins are localized in the cytoplasm They vary in how their cell membrane is protected – some species have specialized surface structures that protect them from their environment or that enable them to move Prokaryotes ...
Final Presentations Abstract Book(1.3 Mb .pdb file)
... Cells of Flavobacterium johnsoniae move over surfaces using gliding motility. Gliding motility is widespread among the phylum Bacteroidetes, and several members cause disease in fish. In gliding motility, surface-exposed adhesins mediate attachment and movement of cells, and are propelled around the ...
... Cells of Flavobacterium johnsoniae move over surfaces using gliding motility. Gliding motility is widespread among the phylum Bacteroidetes, and several members cause disease in fish. In gliding motility, surface-exposed adhesins mediate attachment and movement of cells, and are propelled around the ...
Currenty we have three DOMAINS Who are these organisms
... There is growing evidence that host/microbial interactions within the gut can have a profound impact on human health and disease; in fact, the intestinal microflora have been shown to influence the innate physiology, biochemistry, immunology, maturation of the vasculature, and gene expression in a h ...
... There is growing evidence that host/microbial interactions within the gut can have a profound impact on human health and disease; in fact, the intestinal microflora have been shown to influence the innate physiology, biochemistry, immunology, maturation of the vasculature, and gene expression in a h ...
Diapositive 1
... Activation of Ras means; rearranging the switch regions through the tight link between threonine 35 (in pink) and the third (g)phosphate of ATP. This rearrangement creates favourable interaction sites with effectors ...
... Activation of Ras means; rearranging the switch regions through the tight link between threonine 35 (in pink) and the third (g)phosphate of ATP. This rearrangement creates favourable interaction sites with effectors ...
2013 version with answers.
... contain a similar binding motif for the transcription factor protein bagatelle X. She wants to know the motif and which sequences hold that motif. Typical case for HMM (Hidden Markov Model). c) A colleague in biophysics has been solving the structure of shikimate transferase in the apo form. This is ...
... contain a similar binding motif for the transcription factor protein bagatelle X. She wants to know the motif and which sequences hold that motif. Typical case for HMM (Hidden Markov Model). c) A colleague in biophysics has been solving the structure of shikimate transferase in the apo form. This is ...
The Five Kingdoms
... decaying organic matter by secreting digestive enzymes into it and absorbing small food molecules into their bodies. – They can be either multicellular or unicellular – Cell walls made of chitin – Ex. Mushrooms, yeast ...
... decaying organic matter by secreting digestive enzymes into it and absorbing small food molecules into their bodies. – They can be either multicellular or unicellular – Cell walls made of chitin – Ex. Mushrooms, yeast ...
Wilson`s disease and the copper ATPase transporters
... of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutations. Proc Natl Acad Sci U S A. 103(14):5302-7. 2006 [PMID: 16567646]. ...
... of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutations. Proc Natl Acad Sci U S A. 103(14):5302-7. 2006 [PMID: 16567646]. ...
presentation source
... • Membrane proteins can be classified as: – transmembrane • an integral protein - requires detergents to remove from membrane ...
... • Membrane proteins can be classified as: – transmembrane • an integral protein - requires detergents to remove from membrane ...
Prokaryotic organisms
... – normal residents of a host, but can cause illness, when the host‘s defences are weakened. ...
... – normal residents of a host, but can cause illness, when the host‘s defences are weakened. ...
Bacterial Cell Structure
... identical subunits forming long strands – two alternating sugars • N-acetylglucosamine (NAG) • N- acetylmuramic acid ...
... identical subunits forming long strands – two alternating sugars • N-acetylglucosamine (NAG) • N- acetylmuramic acid ...
Powerpoint
... identical subunits forming long strands – two alternating sugars • N-acetylglucosamine (NAG) • N- acetylmuramic acid ...
... identical subunits forming long strands – two alternating sugars • N-acetylglucosamine (NAG) • N- acetylmuramic acid ...
Lecture-2 Glimpses of Microbial World 1. Discuss the difference
... 1. Discuss the difference between Gram positive and Gram negative cell wall of the bacteria Answer: Gram-positive cell walls consist of many layers of peptidoglycan and do not posses a lipid outer membrane. Gram-negative cell walls on the other hand have only one or a few layers of peptidoglycan but ...
... 1. Discuss the difference between Gram positive and Gram negative cell wall of the bacteria Answer: Gram-positive cell walls consist of many layers of peptidoglycan and do not posses a lipid outer membrane. Gram-negative cell walls on the other hand have only one or a few layers of peptidoglycan but ...
EPIgeneousTM Binding Domain Assays
... enabling FRET to occur upon light excitation. The specific signal at 665 nm is inhibited when a specific compound prevents the reader domain protein from binding to its substrate. ...
... enabling FRET to occur upon light excitation. The specific signal at 665 nm is inhibited when a specific compound prevents the reader domain protein from binding to its substrate. ...
Gene Section NLRC4 (NLR Family, CARD domain containing 4)
... 3.370kb with an ORF encoding 1024 amino acids. CLAN-B, C and D have exon 4 spliced selectively to other exons forming shorter transcripts. Tumor suppressor p53 activates transcription of full length NLRC4 mRNA by binding to a site in the minimal promoter. ...
... 3.370kb with an ORF encoding 1024 amino acids. CLAN-B, C and D have exon 4 spliced selectively to other exons forming shorter transcripts. Tumor suppressor p53 activates transcription of full length NLRC4 mRNA by binding to a site in the minimal promoter. ...
OldExam 1
... A. Their proteins are relatively stable at high temperatures. B. They have lipids in their membranes. C. Their proteins are relatively unstable at high temperatures. D. Their genomes are made of DNA. E. They often cannot grow at low temperatures. -----------5. If a strain of bacteria requires 20 hou ...
... A. Their proteins are relatively stable at high temperatures. B. They have lipids in their membranes. C. Their proteins are relatively unstable at high temperatures. D. Their genomes are made of DNA. E. They often cannot grow at low temperatures. -----------5. If a strain of bacteria requires 20 hou ...
Formation of a membrane
... which forms around a small droplet of water (instead of oil) is called a "Vesicle". Instead of a single membrane where all the tails stuck into an oil droplet there is a second inner membrane that has the phospholipid molecules pointing the other way so their heads contact the water droplet on the i ...
... which forms around a small droplet of water (instead of oil) is called a "Vesicle". Instead of a single membrane where all the tails stuck into an oil droplet there is a second inner membrane that has the phospholipid molecules pointing the other way so their heads contact the water droplet on the i ...
1.Infectious diseases
... – In endogenous infections, the microorganism (usually a bacterium) is a component of the patient;s indigenous flora. Endogenous infections can occur when the microorganism is aspirated from the upper to the lower respiratory tract or when it penetrates the skin or mucosal barrier as a ...
... – In endogenous infections, the microorganism (usually a bacterium) is a component of the patient;s indigenous flora. Endogenous infections can occur when the microorganism is aspirated from the upper to the lower respiratory tract or when it penetrates the skin or mucosal barrier as a ...
PROTEINS Proteins play key roles in living systems
... atoms of residues that are sequentially distant (tertiary) (Zinc fingers) •Drive formation of quaternary structure by coordinating atoms of residues on different subunits (pancreatic insulin) •Serve as acid catalysts •Serve as electron transfer centers (Ribonucleotide reductase) ...
... atoms of residues that are sequentially distant (tertiary) (Zinc fingers) •Drive formation of quaternary structure by coordinating atoms of residues on different subunits (pancreatic insulin) •Serve as acid catalysts •Serve as electron transfer centers (Ribonucleotide reductase) ...
No Slide Title
... Prediction methods exist for all kinds of motifs, signals etc. in newly discovered protein sequences. These are based on either the protein sequence itself or its comparison to protein families (a multiple sequence alignment) Combining these predictions with primary biochemical data can provide valu ...
... Prediction methods exist for all kinds of motifs, signals etc. in newly discovered protein sequences. These are based on either the protein sequence itself or its comparison to protein families (a multiple sequence alignment) Combining these predictions with primary biochemical data can provide valu ...
Pfam-A
... Prediction methods exist for all kinds of motifs, signals etc. in newly discovered protein sequences. These are based on either the protein sequence itself or its comparison to protein families (a multiple sequence alignment) Combining these predictions with primary biochemical data can provide valu ...
... Prediction methods exist for all kinds of motifs, signals etc. in newly discovered protein sequences. These are based on either the protein sequence itself or its comparison to protein families (a multiple sequence alignment) Combining these predictions with primary biochemical data can provide valu ...
domain_rearrangement..
... Work in this area is just beginning. There are many questions still to be answered. ...
... Work in this area is just beginning. There are many questions still to be answered. ...
Gene Section KCMF1 (potassium channel modulatory factor 1) in Oncology and Haematology
... KCMF1 (also known as FIGC) encode a RING finger protein, has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination. KCMF1 contains a novel C6H2-type RING finger domain at the NH2-terminal region, consensus sequence CX2C(7-11) CX2CXA5CX2CX(5-9) HX (1-3) H (XA: acidic residues). Using dif ...
... KCMF1 (also known as FIGC) encode a RING finger protein, has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination. KCMF1 contains a novel C6H2-type RING finger domain at the NH2-terminal region, consensus sequence CX2C(7-11) CX2CXA5CX2CX(5-9) HX (1-3) H (XA: acidic residues). Using dif ...
Trimeric autotransporter adhesin
In molecular biology, trimeric autotransporter adhesins (TAAs), are proteins found on the outer membrane of Gram-negative bacteria. Bacteria use TAAs in order to infect their host cells via a process called cell adhesion. TAAs also go by another name, oligomeric coiled-coil adhesins, which is shortened to OCAs. In essence, they are virulence factors, factors that make the bacteria harmful and infective to the host organism.TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis, and meningitis. Most bacteria infect their host through a method named the secretion pathway. TAAs are part of the secretion pathway, to be more specific the type Vc secretion system.Trimeric autotransporter adhesins have a unique structure. The structure they hold is crucial to their function. They all appear to have a head-stalk-anchor structure. Each TAA is made up of three identical proteins, hence the name trimeric. Once the membrane anchor has been inserted into the outer membrane, the passenger domain passes through it into the host extracellular environment autonomously, hence the description of autotransporter. The head domain, once assembled, then adheres to an element of the host extracellular matrix, for example, collagen, fibronectin, etc.