Chem*3560 Lecture 24: Membrane proteins
... Type I is like glycophorin, a single transmembrane helix, N-terminal outside. Type II is also a single transmembrane helix, but with N-terminal inside. Type III consists of a bundle of helices in a single polypeptide, which may assemble together to form a transmembrane channel, e.g. for substrate tr ...
... Type I is like glycophorin, a single transmembrane helix, N-terminal outside. Type II is also a single transmembrane helix, but with N-terminal inside. Type III consists of a bundle of helices in a single polypeptide, which may assemble together to form a transmembrane channel, e.g. for substrate tr ...
Leukaemia Section t(10;16)(q22;p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Schematic representation of the fusion MYST4-CREBBP consequence of the t(10;16)(q22;p13). From up to down: MYST4 and CREBBP structures. H15 domain: domain in histone families 1 and 5; PHD zinc fingers: plant homeodomain (PHD) with a C4HC3-type motif, this domain is widely distributed in eukaryotes a ...
... Schematic representation of the fusion MYST4-CREBBP consequence of the t(10;16)(q22;p13). From up to down: MYST4 and CREBBP structures. H15 domain: domain in histone families 1 and 5; PHD zinc fingers: plant homeodomain (PHD) with a C4HC3-type motif, this domain is widely distributed in eukaryotes a ...
Molecular evolution of threonine dehydratase in bacteria
... about intracellular signaling and cell-cell fusion Alpha-agglutinin of alpha-cells; binds to Aga1p during agglutination; N-terminal half: homologous to the immunoglobulin superfamily; C-terminal half: highly glycosylated and contains GPI anchor Localized to sites of polarized growth; up-regulated in ...
... about intracellular signaling and cell-cell fusion Alpha-agglutinin of alpha-cells; binds to Aga1p during agglutination; N-terminal half: homologous to the immunoglobulin superfamily; C-terminal half: highly glycosylated and contains GPI anchor Localized to sites of polarized growth; up-regulated in ...
S-layer Structure in Bacteria and Archaea
... (A-layer) imparts high to moderate levels of anti-bactericidal activity against complement systems (Dworkin and Blaser 1997). The A-layer also imparts an adhesive property, able to bind laminins, fibronectins (Doig et al. 1992) and basement membrane protein collagen type IV (Trust et al. 1993). In o ...
... (A-layer) imparts high to moderate levels of anti-bactericidal activity against complement systems (Dworkin and Blaser 1997). The A-layer also imparts an adhesive property, able to bind laminins, fibronectins (Doig et al. 1992) and basement membrane protein collagen type IV (Trust et al. 1993). In o ...
Solid-State NMR Studies of the Structure of Membrane Bound Ras
... H-Ras and K-Ras are PM -associated proteins, which are ubiquitously expressed in mammalian cells. These highly homologous proteins interact in vitro with the same set of effectors but generate distinct signaling outputs in vivo [24]. K-Ras is a more potent activator of Raf-1 than H-Ras, but is a les ...
... H-Ras and K-Ras are PM -associated proteins, which are ubiquitously expressed in mammalian cells. These highly homologous proteins interact in vitro with the same set of effectors but generate distinct signaling outputs in vivo [24]. K-Ras is a more potent activator of Raf-1 than H-Ras, but is a les ...
domain alignments - Oxford Academic
... link and expanding the summary to show more details will produce a graphical display, as shown in Figure 1. While the protein maps to a conserved family of unknown function (DUF135/pfam02003), the sequence also produces hits to two models for DNA ligases (pfam01068 and LOAD_ligase). In fact these th ...
... link and expanding the summary to show more details will produce a graphical display, as shown in Figure 1. While the protein maps to a conserved family of unknown function (DUF135/pfam02003), the sequence also produces hits to two models for DNA ligases (pfam01068 and LOAD_ligase). In fact these th ...
Segregation of open major histocompatibility class I conformers at
... Fully conformed major histocompatibility class I molecules are complexes of heavy chain noncovalently associated with the peptide and 2-microglobulin. Conformational change in the extracellular domain of heavy chain leads to their disassembly and formation of open conformers, a process that physio ...
... Fully conformed major histocompatibility class I molecules are complexes of heavy chain noncovalently associated with the peptide and 2-microglobulin. Conformational change in the extracellular domain of heavy chain leads to their disassembly and formation of open conformers, a process that physio ...
Lab Week 2
... Simple staining involves one dye Differential staining used to distinguish different types of bacteria ...
... Simple staining involves one dye Differential staining used to distinguish different types of bacteria ...
Gene Section PTPN21 (protein tyrosine phosphatase, non- receptor type 21)
... kinase. PTPD1/src complex up-regulates epidermal growth factor receptor (EGFR) phosphorylation and increases ERK 1 / ERK 2 signaling in response to EGF. PTPD1 forms a stable complex with actin, src tyrosine kinase and FAK (Focal Adhesion Kinase). PTPD1 regulates FAK signalling and actin cytoskeleton ...
... kinase. PTPD1/src complex up-regulates epidermal growth factor receptor (EGFR) phosphorylation and increases ERK 1 / ERK 2 signaling in response to EGF. PTPD1 forms a stable complex with actin, src tyrosine kinase and FAK (Focal Adhesion Kinase). PTPD1 regulates FAK signalling and actin cytoskeleton ...
Chapter 18 Bacteria Notes
... • Bacteria are 1- celled organisms that live everywhere. They are the oldest life forms on Earth. E. coli is the most studied bacterium. All bacteria are prokaryotic meaning they have no true nucleus (they do still have genetic material). Bacteria do contain cell walls containing acids & sugars that ...
... • Bacteria are 1- celled organisms that live everywhere. They are the oldest life forms on Earth. E. coli is the most studied bacterium. All bacteria are prokaryotic meaning they have no true nucleus (they do still have genetic material). Bacteria do contain cell walls containing acids & sugars that ...
- SlideBoom
... bacterial species are generally more pathogenic than disease-causing gram-positive bacteria. ...
... bacterial species are generally more pathogenic than disease-causing gram-positive bacteria. ...
MICROBES Microbes - 2 basic types 1. Eukaryotes
... - through portals of entry such as breaks in the skin or through exposed mucous membranes of the eye, respiratory tract, digestive tract, reproductive tract, urinary tract. - some pathogen have specific areas of entry - such as cold viruses that enter through the respiratory tract. How are pathogens ...
... - through portals of entry such as breaks in the skin or through exposed mucous membranes of the eye, respiratory tract, digestive tract, reproductive tract, urinary tract. - some pathogen have specific areas of entry - such as cold viruses that enter through the respiratory tract. How are pathogens ...
Domain structure and sequence similarities in cartilage proteoglycan
... For link protein alone, comparison among different species shows the amino acid sequence similarity between these two loops to be almost 60%. The G1 domain has been shown to bind specifically to hyaluronate [6].Evidence from immunochemical data using antibodies raised specifically to G1 and G 2 doma ...
... For link protein alone, comparison among different species shows the amino acid sequence similarity between these two loops to be almost 60%. The G1 domain has been shown to bind specifically to hyaluronate [6].Evidence from immunochemical data using antibodies raised specifically to G1 and G 2 doma ...
tutorial10_3D_structure
... large biological molecules, mostly proteins and nucleic acids: ~87,000 structures. • The data is typically obtained by X-ray crystallography or NMR (Nuclear magnetic resonance) spectroscopy and submitted by biologists and biochemists from around the world. ...
... large biological molecules, mostly proteins and nucleic acids: ~87,000 structures. • The data is typically obtained by X-ray crystallography or NMR (Nuclear magnetic resonance) spectroscopy and submitted by biologists and biochemists from around the world. ...
Building the Tree of Life
... Genetic analysis has revealed that the two main prokaryotic kingdoms are more different from each other, and from eukaryotes, than previously thought. So, biologists established a new taxonomic category—the domain. A domain is a larger, more inclusive category than a kingdom. Under this system, ther ...
... Genetic analysis has revealed that the two main prokaryotic kingdoms are more different from each other, and from eukaryotes, than previously thought. So, biologists established a new taxonomic category—the domain. A domain is a larger, more inclusive category than a kingdom. Under this system, ther ...
single molecule elasticity of dna
... http://gened.emc.maricopa.edu/Bio/BIO181/BIOBK/BioBookCELL2.html ...
... http://gened.emc.maricopa.edu/Bio/BIO181/BIOBK/BioBookCELL2.html ...
Microbe Math
... 1. Ask students for examples of decay they have seen, such as food left in the refrigerator too long or a dead animal in the yard. Explain that bacteria and fungi cause most of the decay. 2. Explain that an individual bacterium is far too small to be seen by our eyes alone; most are about 1/1000 of ...
... 1. Ask students for examples of decay they have seen, such as food left in the refrigerator too long or a dead animal in the yard. Explain that bacteria and fungi cause most of the decay. 2. Explain that an individual bacterium is far too small to be seen by our eyes alone; most are about 1/1000 of ...
Bacteria I
... • long, whip-like structures for motility (movement) • location is important in identifying unknowns ...
... • long, whip-like structures for motility (movement) • location is important in identifying unknowns ...
Title - Iowa State University
... 3. A gram-positive__ bacteria has a thick cell wall made of peptidoglycan that causes it to appear purple_ during gram staining. 4. A gram-negative bacteria has a thin layer of peptidoglycan sandwiched between two membranes that causes it to appear _pink/red_ during gram staining. 5. Match the follo ...
... 3. A gram-positive__ bacteria has a thick cell wall made of peptidoglycan that causes it to appear purple_ during gram staining. 4. A gram-negative bacteria has a thin layer of peptidoglycan sandwiched between two membranes that causes it to appear _pink/red_ during gram staining. 5. Match the follo ...
11-12 Peptide Hormones
... glands into the bloodstream where they travel to a distant site and change the pace or architecture of the target tissue. • Hypothalamus in the brain is the mission control center ...
... glands into the bloodstream where they travel to a distant site and change the pace or architecture of the target tissue. • Hypothalamus in the brain is the mission control center ...
Steroid Hormones
... glands into the bloodstream where they travel to a distant site and change the pace or architecture of the target tissue. • Hypothalamus in the brain is the mission control center ...
... glands into the bloodstream where they travel to a distant site and change the pace or architecture of the target tissue. • Hypothalamus in the brain is the mission control center ...
PDF version
... Like us, bacteria have to move if they want to get somewhere. Or away from something. We take the bus, hop into a car, use our legs or climb onto a bicycle. Different bacteria have different means of locomotion that they have had ample time to perfect since their first appearance on earth millions o ...
... Like us, bacteria have to move if they want to get somewhere. Or away from something. We take the bus, hop into a car, use our legs or climb onto a bicycle. Different bacteria have different means of locomotion that they have had ample time to perfect since their first appearance on earth millions o ...
Exam #1
... What are the four phases of growth in a batch (closed) culture? Understand what is happening in each phases of the “growth curve”. When growth is balanced versus unbalanced; what’s that mean? Exponential (log) growth phase is used to calculate growth rate constant (k). How is this done? If you know ...
... What are the four phases of growth in a batch (closed) culture? Understand what is happening in each phases of the “growth curve”. When growth is balanced versus unbalanced; what’s that mean? Exponential (log) growth phase is used to calculate growth rate constant (k). How is this done? If you know ...
Microbial Taxonomy
... properties and differ significantly from other groups of strains الدين علي جتني عز.د.م.أ • Species are identified by comparison with known strains”: well-جامعة “االسنانtype كلية طب – تكريت characterized pure cultures; references for the identification of unknowns • There are sever ...
... properties and differ significantly from other groups of strains الدين علي جتني عز.د.م.أ • Species are identified by comparison with known strains”: well-جامعة “االسنانtype كلية طب – تكريت characterized pure cultures; references for the identification of unknowns • There are sever ...
Trimeric autotransporter adhesin
In molecular biology, trimeric autotransporter adhesins (TAAs), are proteins found on the outer membrane of Gram-negative bacteria. Bacteria use TAAs in order to infect their host cells via a process called cell adhesion. TAAs also go by another name, oligomeric coiled-coil adhesins, which is shortened to OCAs. In essence, they are virulence factors, factors that make the bacteria harmful and infective to the host organism.TAAs are just one of many methods bacteria use to infect their hosts, infection resulting in diseases such as pneumonia, sepsis, and meningitis. Most bacteria infect their host through a method named the secretion pathway. TAAs are part of the secretion pathway, to be more specific the type Vc secretion system.Trimeric autotransporter adhesins have a unique structure. The structure they hold is crucial to their function. They all appear to have a head-stalk-anchor structure. Each TAA is made up of three identical proteins, hence the name trimeric. Once the membrane anchor has been inserted into the outer membrane, the passenger domain passes through it into the host extracellular environment autonomously, hence the description of autotransporter. The head domain, once assembled, then adheres to an element of the host extracellular matrix, for example, collagen, fibronectin, etc.