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Nervous
Nervous

... region of the membrane, re-initiating the action potential there. To the left of this region, the membrane is repolarizing as K+ flows outward. ...
Nervous System - Academic Computer Center
Nervous System - Academic Computer Center

... the postsynaptic cell or within the synaptic cleft; reuptake by astrocytes or the presynaptic cell; or diffusion away from the synapse. ...
The Nervous System
The Nervous System

... ensues, depolarizing the cell and causing the VM to increase. This is the rising phase of an AP. • Eventually, the Na+ channel will have inactivated and the K+ channels will be open. Now, K+ effluxes and repolarization occurs. This is the falling phase. – K+ channels are slow to open and slow to clo ...
File
File

... Application: Secretion and reabsorption of acetylcholine by neurons at synapses.  Acetylcholine is a neurotransmitter  It is largely used at the neuromuscular junction, meaning it is released by motor neurons and binds to receptors on muscles  It is also used in the autonomic nervous system  Ace ...
No Slide Title
No Slide Title

... potential is triggered – this is called the ‘all-or-none rule’. • Following the action potential, the sodium gates remain closed for around 1ms and so further action potentials cannot be triggered regardless of the stimulation. • This is called the absolute refractory period. • The sodium gates then ...
File - Ms Curran`s Leaving Certificate Biology
File - Ms Curran`s Leaving Certificate Biology

...  The movement of the electrical impulse along a neuron involves the movement of ions.  When an neuron is Not carrying an impulse ions are pumped in & out of the axon. This results in the inside of the axon being –ive and the outside +ive  Threshold, is the minimum stimulus needed to cause an impu ...
Part 1: True/False
Part 1: True/False

... 2. __ The EPSPs in the central nervous system are much smaller than end plate potentials. 3. __ An IPSP can depolarize or hyperpolarize a cell. 4. __ All neurotransmitters are synthesized in the soma and carried to the axon terminal through axoplasmic transport. 5. __ The two main families of neurot ...
LO #1
LO #1

... Gap junctions provide a non-selective conductance path between the two cells, passing ions and second messengers.  Because this current is non-selective, the reversal potential for the current is 0 mV.  No current flows when the two cells are at the same voltage. ...
THE SYNAPSE
THE SYNAPSE

... feature of the synapse is the accumulation of opaque material on the cytoplasmic face of the postsynaptic membrane. This material is refered to as the postsynaptic density. The density represents the aggregation of neurotransmitter receptors and signaling proteins essential for chemical synaptic tra ...
file - Athens Academy
file - Athens Academy

... maintain our sanity, having an imbalance in this neurotransmitter plays a role in the development of Parkinson’s Disease. ...
nervous5
nervous5

... Exceptions: Peptide NTs originate in cell body, move in vesicles by fast orthograde axonal transport to axon terminal. ...
E4 - Neurotransmitters and Synapses - IBDPBiology-Dnl
E4 - Neurotransmitters and Synapses - IBDPBiology-Dnl

... summation of input from pre-synaptic neurons  EPSPs depolarize post-synaptic neurons while  IPSPs hyper-polarize post-synaptic neurons  if the post-synaptic neuron reaches threshold potential at its axon hillock, it will produce an action potential  pre-synaptic neurons can vary in the frequency ...
Nerve Impulse Transmission
Nerve Impulse Transmission

... rapidly rises and falls - this acts as the signal/message to be repeated & sent along the neuron's axon ...
Trigeminal Ganglion Cell
Trigeminal Ganglion Cell

... Trigeminal Ganglion Cell: this is about 2 seconds of activity that was recorded from a ganglion cell after the maxillary (upper) incisor tooth of an anesthetized rat was tapped 5 times. Listen for 5 distinct "bursts" of action potentials. Trigeminal Ganglion Cell: this is about 2 seconds of activi ...
File
File

... Credit: Mark Lythgoe & Chloe Hutton, Wellcome Images ...
Synaptic Transmission - Grand Haven Area Public Schools
Synaptic Transmission - Grand Haven Area Public Schools

... •How a neuron communicates with another neuron and the effects of drugs on this process. •Types of Neurotransmitters ...
vocabulary worksheet
vocabulary worksheet

... 27. The _______________ is the outermost covering of the brain consisting of densely packed neurons, responsible for higher thought processes and interpretation of sensory input. 28. The thick band of neurons that connects the right and left cerebral hemispheres is called the _________________ _____ ...
Psych 11Nervous System Overview
Psych 11Nervous System Overview

...  Step 4: Neurotransmitters diffuse across the synaptic cleft (a very short distance) and bind to receptor proteins on the postsynaptic membrane. Excitatory neurotransmitters cause sodium ions to move through receptor proteins depolarizing the membrane. Inhibitory neurotransmitters do not depolarize ...
The Nervous System
The Nervous System

... There are more Na+ (sodium) ions outside and fewer K+ (potassium) ions inside. ...
Heart
Heart

... - cell can regulate whether it is open or not (deactivated) - channel is specific for particular molecule Osmosis -solvent molecules go through semipermeable membrane from low concentration site to the higher concentration site  development of chemical potential Aktivní transport - cell has to do a ...
Neurotoxicology
Neurotoxicology

... -- high metabolic demands of CNS -- relatively large surface area and complex geometry of some cells -- high lipid content of some structures -- multiple potential mechanisms for toxic effects -- critical role in integration of bodily functions, multiple potential types of effects, subtle impairment ...
The master controlling and communicating system of the body Functions
The master controlling and communicating system of the body Functions

... Neurotransmitter receptors mediate changes in membrane potential according to: o The amount of neurotransmitter released o The amount of time the neurotransmitter is bound to receptors ...
Control and Integration Nervous System Organization: Radial
Control and Integration Nervous System Organization: Radial

... – opening of chemically-gated or physically-gated ion channels – travels only a short distance (few mm) ...
Resting Membrane Potential
Resting Membrane Potential

... resting to firing? • The resting membrane potential of a neuron is -70 mV • In order for a neuron to fire a signal, the membrane potential must reach a certain threshold, around -55 mV. • This happens when another neuron stimulates it and allows a few Na+ channels to open and a few Na+ ions enter th ...
Ling 8700: Lecture Notes 1 A Model of Neural Activation
Ling 8700: Lecture Notes 1 A Model of Neural Activation

... 4. if potential changes enough, voltage-gated channels come open; 5. voltage-gated channels let in many Na+ /Ca++ ions; neuron depolarizes (this is a non-linear threshold function on the sum of positive/negative ions in the neuron); 6. depolarization allows vesicles to meet surface, release neurotra ...
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Nonsynaptic plasticity



Nonsynaptic plasticity is a form of neuroplasticity that involves modification of ion channel function in the axon, dendrites, and cell body that results in specific changes in the integration of excitatory postsynaptic potentials (EPSPs) and inhibitory postsynaptic potentials (IPSPs). Nonsynaptic plasticity is a modification of the intrinsic excitability of the neuron. It interacts with synaptic plasticity, but it is considered a separate entity from synaptic plasticity. Intrinsic modification of the electrical properties of neurons plays a role in many aspects of plasticity from homeostatic plasticity to learning and memory itself. Nonsynaptic plasticity affects synaptic integration, subthreshold propagation, spike generation, and other fundamental mechanisms of neurons at the cellular level. These individual neuronal alterations can result in changes in higher brain function, especially learning and memory. However, as an emerging field in neuroscience, much of the knowledge about nonsynaptic plasticity is uncertain and still requires further investigation to better define its role in brain function and behavior.
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