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The Nervous System - Volunteer State Community College
The Nervous System - Volunteer State Community College

... temporarily more negative than the resting stage (hyperpolarized); Na+ channels remain closed but K+ channels remain open since the inactivation gates have not had time to respond to repolarization of the membrane. ...
Nervous System
Nervous System

... involuntary action ...
Inhibitory postsynaptic potential
Inhibitory postsynaptic potential

... – Excitatory postsynaptic potential (EPSP) – produces a small local depolarization, pushing the cell closer to threshold – Inhibitory postsynaptic potential (IPSP) – produces a small hyperpolarization, pushing the cell further away from threshold ...
Integrate and Fire Neural Network
Integrate and Fire Neural Network

... – Simulation specifics, intro to neural network models, suggestions for this presentation ...
A neuron receives input from other neurons
A neuron receives input from other neurons

... Neurons can be thought of as the basic processing units of the brain and convey signals by passing electrical impulses called action potentials from one end of themselves to another. Action potentials are generated by the opening and closing of microscopic gates in the cell membrane. At the end of t ...
Neurones & the Action Potential
Neurones & the Action Potential

... Contribution of Active Transport There are different numbers of potassium ions (K+) and sodium ions (Na+) on either side of the membrane. Even when a nerve cell is not conducting an impulse, for each ATP molecule that’s hydrolysed, it is actively transporting 3 molecules Na+ out of the cell and 2 m ...
Modification of brain circuits as a result of experience
Modification of brain circuits as a result of experience

... repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A's efficiency, as one of the cells firing B, is increased. • Correlated activity between presynaptic and postsynaptic cells strengthens synaptic connections between ...
Neural Tissue – Chapter 12
Neural Tissue – Chapter 12

... from its outer surface. These ions move toward the open channels, replacing ions that have already entered the cell. This is called local current. (As sodium ions move into the cell, other sodium ions fill in the gaps.) This causes adjacent portions of the cell membrane to become depolarized. The de ...
Nervous System
Nervous System

... As Na+ goes into cell, neuron goes from being polarized to depolarized When inside becomes positive, polarization is removed and the threshold is reached K+ ions move outside, Na+ ions stay inside membrane Refractory period returns everything ...
Neurophysiology Neurotransmitter and Nervous System
Neurophysiology Neurotransmitter and Nervous System

... an action potential arrives at the terminal bouton, it causes Ca++ channels to open.  This causes the vesicles to move to the membrane and release a chemical called a neurotransmitter to be released into the synaptic cleft.  The neurotransmitter diffuses across the cleft and activates receptors on ...
13. Electrochemical Impulse
13. Electrochemical Impulse

... Electrochemical Impulse It has long been known that electrical impulses are present in living organisms, but it is only within the last century that we have understood how and why neurons transmit electricity These impulses are generated using uneven concentrations of ions inside the neuron compared ...
NERVES
NERVES

... and open or close when a specific channel when a specific chemical binds to the channel › Voltage-gated ion channels- are found in axons and open or close when the membrane potential changes ...
Feb. 11
Feb. 11

... – Principle of connectional specificity: neurons  make specific connections at precise points of  synaptic contact. ...
Document
Document

... -Positive charges due to influx of Na+ can depolarize the adjacent region to threshold -And so the next region produces its own action potential -Meanwhile, the previous region repolarizes back to the resting membrane potential ...
Materialy/06/Lecture12- ICM Neuronal Nets 1
Materialy/06/Lecture12- ICM Neuronal Nets 1

... 1947: McCulloch and Pitt described a behaviour of connected neurons 1949: Hebb designed a net with memory 1958: Rosenblatt described learning (“back propagation”) 1962: first neurocomputer ...
structure and function of the neurologic system
structure and function of the neurologic system

... – Regeneration more optimistic if injury further away from cell body – With regeneration, see: • Swelling distal to injury • Filaments hypertrophy ...
Dopamine axons of substantia nigra pars compacta neurons and
Dopamine axons of substantia nigra pars compacta neurons and

... selective vulnerability. One factor that distinguishes SNc DA neurons from other DA neurons is their massive axonal arbour and the massive number of synapses they establish. We propose that the high energy cost of such a massive axonal architecture puts SNc DA neurons energetically ‘on the edge’ suc ...
Chapter 9 Nervous
Chapter 9 Nervous

... Na ions are transferred out into extracellular fluid. K ions are transferred into cell within cytoplasm. This is threshold potential. The permeability of the cell membrane increases, allowing Na to rush into the cell. Cells interior takes a positive charge. (Called depolarization) Depolarization swe ...
Bio70 Psychobiology Fall 2006 First Midterm October 12 Version A
Bio70 Psychobiology Fall 2006 First Midterm October 12 Version A

... 23. Which of the following is true of local neurons? a. They exchange information with distant neurons. b. They abide by the all-or-none principle. c. The change in membrane potential increases as it travels. d. They have short dendrites and axons. ...
How Neurons Communicate - Computing Science and Mathematics
How Neurons Communicate - Computing Science and Mathematics

... • Neurotransmitter binds to postsynaptic receptors (ion channels), causing them to open • The resulting ionic current generates the PSP AP ...
Biology and Behaviour
Biology and Behaviour

... transmission rate Less resistance with a big axon Normally you have a resting potential because a process called Active Transport pump out Na+ and pulls K+ in (3:2) so you get a negative charge across the cell membrane ...
chapter 48
chapter 48

... Glia are supporting cells that _______________________________, insulate the _________________ ___________________, and regulate the __________________________________________________. o Some glia form the blood brain barrier  restricts passage of most substances into the brain which controls the c ...
Development of the Cerebral Cortex: VI. Growth Factors
Development of the Cerebral Cortex: VI. Growth Factors

... that are secreted by the target nerve cells, bind to specific receptors, and signal to the nearby developing synapse. Within the nervous system, the most extensively studied of these factors is the family of neurotrophins. Almost 50 years ago, Rita Levi-Montalcini and Stanley Cohen isolated and iden ...
Unit 3A Notes
Unit 3A Notes

... 3. Axons are long “arms” that send info away from the cell body to other neurons or body parts. 1. Axons are insulated by the myelin sheath. This insulation helps control the impulses and speeds their travel. 2. Messages travel along neurons at between 2 and 200 mph (depending on the type of neuron) ...
Neural Development - Peoria Public Schools
Neural Development - Peoria Public Schools

... • Synapses can be formed at any stage in life. • When used: a. Chemical markers are left that strengthen a synapse. • When not used: a. Synapse is weak due to no chemical markers. ...
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Nonsynaptic plasticity



Nonsynaptic plasticity is a form of neuroplasticity that involves modification of ion channel function in the axon, dendrites, and cell body that results in specific changes in the integration of excitatory postsynaptic potentials (EPSPs) and inhibitory postsynaptic potentials (IPSPs). Nonsynaptic plasticity is a modification of the intrinsic excitability of the neuron. It interacts with synaptic plasticity, but it is considered a separate entity from synaptic plasticity. Intrinsic modification of the electrical properties of neurons plays a role in many aspects of plasticity from homeostatic plasticity to learning and memory itself. Nonsynaptic plasticity affects synaptic integration, subthreshold propagation, spike generation, and other fundamental mechanisms of neurons at the cellular level. These individual neuronal alterations can result in changes in higher brain function, especially learning and memory. However, as an emerging field in neuroscience, much of the knowledge about nonsynaptic plasticity is uncertain and still requires further investigation to better define its role in brain function and behavior.
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