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Centromere Locations and Associated Chromosome
Centromere Locations and Associated Chromosome

... CEN5 is more complex. The formation of chromosome V of A. thaliana involved a reciprocal translocation (see above and Figure 1), and an understanding of this event is critical for interpreting the origin of CEN5. Previous comparative molecular cytogenetic analyses of A. thaliana and A. lyrata could ...
A MIAME-compliant Microarray Database
A MIAME-compliant Microarray Database

The Complex Inheritance of Maize Domestication Traits and Gene
The Complex Inheritance of Maize Domestication Traits and Gene

... was given to shepherd them to completion. Every day and conversation I have had with John as my advisor has made me into a better scientist and I am extremely thankful for the opportunity I was given six years ago when I joined the Doebley lab. I have been fortunate enough to also work in an outstan ...
Relative Paucity of Genes Causing Inviability in Hybrids
Relative Paucity of Genes Causing Inviability in Hybrids

... be distinguished by crossing these balancer stocks to a D. simulans strain homozygous for cinnabar (we preferred to use the eye-color mutation because Curly sometimes has variable expressivity, and so we could check progeny using two independent mutations). Most of our D. melanogaster X-chromosome d ...
Evolutionary dynamics of nematode operons
Evolutionary dynamics of nematode operons

... 2006), and several models have been proposed to explain the prevalence of operons in prokaryotes (Lawrence and Roth 1996; Lawrence 1999). However, these models are not applicable to nematode operons. For example, the natal model claims that genes found in operons are in situ duplicates (Lawrence 199 ...
Document
Document

... absence of cytokinin. I have done the same for double and triple mutants as well as transgenic lines overexpressing these genes that I have generated. This genetic approach has revealed some functional redundancy between CRF genes with one specific CRF gene pair necessary for normal embryo developme ...
Hox Targets and Cellular Functions
Hox Targets and Cellular Functions

... expressed later and more posteriorly in the A/P axis, whereas those located at the other end of the complex are expressed earlier and more anteriorly [18, 19]. Hox genes code for proteins that bind DNA and regulate the expression of different targets. Hox proteins include a highly conserved sequence ...
Comparative analysis of two-component signal transduction systems
Comparative analysis of two-component signal transduction systems

... are often encoded on adjacent genes. A typical HK contains an N-terminal, membrane-associated sensor domain and a C-terminal, cytosolic H-box and HATPase domain. Together, these cytoplasmic domains make up the phosphotransferase domain. A typical RR is a cytosolic protein consisting of an N-terminal ...
Hox patterning of the vertebrate axial skeleton
Hox patterning of the vertebrate axial skeleton

... Together, these experiments provided strong evidence that the HomC genes are critical AP patterning cues in the development of the body plan in Drosophila. In single Hox mutant mice, however, some defects have been characterized as anterior homeotic transformations—the kinds of transformations that ...
Life 9e - Garvness
Life 9e - Garvness

... Bloom’s Category: 1. Remembering 15. The site on the chromosome occupied by a gene is called a(n) a. allele. b. region. c. locus. d. type. e. phenotype. Answer: c Textbook Reference: 12.1 What Are the Mendelian Laws of Inheritance? Page: 241 Bloom’s Category: 1. Remembering 16. Which of the followi ...
Role of two-component systems in the virulence of Streptococcus
Role of two-component systems in the virulence of Streptococcus

... pneumococcal polysaccharide capsule have significant disadvantages (Bogaert et al., 2004). In the case of purified polysaccharides, these are poorly immunogenic in children under 2 years old, an age group that suffers a high incidence of pneumococcal disease. Conjugate vaccines with purified capsula ...
Pitx1 and Pitx2 are required for development of hindlimb buds
Pitx1 and Pitx2 are required for development of hindlimb buds

Conservation and diversification of gene function during mouthpart
Conservation and diversification of gene function during mouthpart

... resembling the maxillary galea (see Fig. 4) in shape, color, and bristle patterning (Fig. 3Bii, iii). In contrast, dac RNAi resulted in a shortening of the medial prementum, but left the mentum and labial palps unaffected (Fig. 3C). Reduction of prementum size rendered the first labial palp segment mo ...
Operon review
Operon review

... INACTIVE (Circle one) INACTIVE (Circle one) ...
Hox patterning of the vertebrate rib cage
Hox patterning of the vertebrate rib cage

... AP regions of the axial skeleton. These combined results suggest that there are alternative mechanisms by which Hox genes govern patterning of the thoracic region. Part of the difficulty in understanding patterning of the rib cage results from the nature of development of the thoracic skeleton. The ...
Hox patterning of the vertebrate rib cage
Hox patterning of the vertebrate rib cage

... AP regions of the axial skeleton. These combined results suggest that there are alternative mechanisms by which Hox genes govern patterning of the thoracic region. Part of the difficulty in understanding patterning of the rib cage results from the nature of development of the thoracic skeleton. The ...
Genome-Wide Identification of Allelic Expression in Hypertensive
Genome-Wide Identification of Allelic Expression in Hypertensive

Genome-Wide Identification of Allelic Expression in Hypertensive Rats
Genome-Wide Identification of Allelic Expression in Hypertensive Rats

... of sequence variation between SHR-A3 and WKY. Among the 36 genes and ESTs surveyed, 21 have been found to be polymorphic between SHR-A3 and WKY. Genotyping assays were developed and used to determine which of these 21 genes share the same allele in all SHR lines (SHR-A3, -B2, -C, and SHR/N), but con ...
RNA interference pathways display high rates of adaptive protein
RNA interference pathways display high rates of adaptive protein

... lower than 5, but we reduced this threshold to 2 for the low-coverage B. mandarina. After mapping and filtering sites we created two randomly resolved pseudohaplotype sequences per individual (i.e. without any linkage information) from the sites that remained, and these were used for downstream anal ...
A Genome-Wide Survey of the NAC Transcription
A Genome-Wide Survey of the NAC Transcription

... Transcription factors are proteins that modulate gene expression by binding to specific cis-acting promoter elements, thereby activating or repressing the transcription of target genes (Wray et al., 2003). Gene specific transcription factors are DNA-binding regulatory proteins that activate or repre ...
Genome-wide analysis of the distribution of AP2/ERF transcription
Genome-wide analysis of the distribution of AP2/ERF transcription

... cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbage and Arabidopsis; therefore, Arabidopsis is a viable reference species for comparative genomics studies. Transcr ...
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine

... (S288C derivative), ST, and VIN7 was used as template for PCR. Genomic DNA from BY4743 was used as control for the PCR reactions. Taq DNA polymerase (MBI Fermentas) was used to generate DNA fragments (using primers listed in Supplementary Table 1). Primers YOL164WF and YOL‑ 164WR were used to genera ...
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink
Genetics of Clubroot Resistance inBrassicaSpecies | SpringerLink

... disease is one of the most serious problems in Chinese cabbage production in Korea and elsewhere. The ability of this pathogen to survive in soil as resting spores for long periods makes it difficult to control by cultural practices or chemical treatments (Voorrips 1995). Thus, breeding of resistant ...
Gene Section DLX6 (distal-less homeobox 6) Atlas of Genetics and Cytogenetics
Gene Section DLX6 (distal-less homeobox 6) Atlas of Genetics and Cytogenetics

... dysregulated in this condition, and whether this trait can be functionaly associated with the phenotype, remains to be elucidated. ...
Correction to “Frequency of Undetected CYP2D6
Correction to “Frequency of Undetected CYP2D6

... arrangement, we determined the percentage of heterozygous samples for each, which had a hybrid tandem. The “Any homozygous genotype” row included any sample with an initial homozygous genotype except those with duplications. Finally, the frequency of hybrid genes in samples originally genotyped as h ...
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Essential gene



Essential genes are those genes of an organism that are thought to be critical for its survival. However, being essential is highly dependent on the circumstances in which an organism lives. For instance, a gene required to digest starch is only essential if starch is the only source of energy. Recently, systematic attempts have been made to identify those genes that are absolutely required to maintain life, provided that all nutrients are available. Such experiments have led to the conclusion that the absolutely required number of genes for bacteria is on the order of about 250-300. These essential genes encode proteins to maintain a central metabolism, replicate DNA, translate genes into proteins, maintain a basic cellular structure, and mediate transport processes into and out of the cell. Most genes are not essential but convey selective advantages and increased fitness.
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