I. Comparing genome sequences
... • Homologous sequences = derived from a common ancestor • Orthologous sequences = homologous sequences separated by a speciation event (e.g., human HOXA and mouse Hoxa) • Paralogous sequences = homologous sequences separated by gene duplication (e.g., human HOXA and human HOXB) ...
... • Homologous sequences = derived from a common ancestor • Orthologous sequences = homologous sequences separated by a speciation event (e.g., human HOXA and mouse Hoxa) • Paralogous sequences = homologous sequences separated by gene duplication (e.g., human HOXA and human HOXB) ...
Text S1. Predicted Functional RNAs Within Coding Regions
... genome screening with four species alignment (Saccharomyces cerevisae, S. paradoxus, S. mikatae, and S. baynus), as described in the “Multi-Species Alignment” section. Using a Linux cluster (6 AMD Opeteron nodes – 2 dual processor, dual core), all other comparisons took approximately one week. The s ...
... genome screening with four species alignment (Saccharomyces cerevisae, S. paradoxus, S. mikatae, and S. baynus), as described in the “Multi-Species Alignment” section. Using a Linux cluster (6 AMD Opeteron nodes – 2 dual processor, dual core), all other comparisons took approximately one week. The s ...
BioCyc Microbial Genomes and Metabolic Pathways Web Portal
... a diverse range of data and providing a high level of curation for important microbes. BioCyc curators summarize and synthesize information from thousands of publications, saving scientists time in literature research, and integrating data for large-scale computational analyses. BioCyc Pathway/Genom ...
... a diverse range of data and providing a high level of curation for important microbes. BioCyc curators summarize and synthesize information from thousands of publications, saving scientists time in literature research, and integrating data for large-scale computational analyses. BioCyc Pathway/Genom ...
Poster
... this end, a score is attributed to each locus in the genome according to the similarity measure defined by the matrix. The output of this functionality is filtered with a cut-off score and then directly used as input by the second one. The second functionality starts by fetching the gene positions o ...
... this end, a score is attributed to each locus in the genome according to the similarity measure defined by the matrix. The output of this functionality is filtered with a cut-off score and then directly used as input by the second one. The second functionality starts by fetching the gene positions o ...
Cold Spring Harbor Laboratory Scientists Produce High
... transcripts, providing a more accurate view of gene structure, gene expression, and important mechanisms such as alternative gene splicing. Iso-Seq analysis of SMRT Sequencing data more than doubled the number of isoforms, corrected numerous previously misannotated gene models, and identified many n ...
... transcripts, providing a more accurate view of gene structure, gene expression, and important mechanisms such as alternative gene splicing. Iso-Seq analysis of SMRT Sequencing data more than doubled the number of isoforms, corrected numerous previously misannotated gene models, and identified many n ...
the smallest dinoflagellate genome is yet to be found: a comment on
... ( 3 109 bp), which would prevent any attempt until sequencing technology becomes drastically cheaper and throughput higher. Any hope for the near future would rest with the possibility of bringing into culture a picoplanktonic dinoflagellate whose genome is at least 10-fold smaller, if such taxon ...
... ( 3 109 bp), which would prevent any attempt until sequencing technology becomes drastically cheaper and throughput higher. Any hope for the near future would rest with the possibility of bringing into culture a picoplanktonic dinoflagellate whose genome is at least 10-fold smaller, if such taxon ...
4. Course administrator
... 10 years so that it can be applied nowadays in several fields like medicine, genomics, proteomics, microbiology, protein chemistry, evolution, plant biology, biotechnology…etc. ...
... 10 years so that it can be applied nowadays in several fields like medicine, genomics, proteomics, microbiology, protein chemistry, evolution, plant biology, biotechnology…etc. ...
How does eukaryotic gene prediction work?
... of an intron. Figure 1e shows the same target sequence in an alignment with a frame-shifting gap and two adjacent mismatches, which undermines the hypothesis that it encodes a protein. The most accurate systems also use position-specific substitution models for splice sites and other signals. Recent ...
... of an intron. Figure 1e shows the same target sequence in an alignment with a frame-shifting gap and two adjacent mismatches, which undermines the hypothesis that it encodes a protein. The most accurate systems also use position-specific substitution models for splice sites and other signals. Recent ...
Hands On - Gene Prediction in Prokaryotes file
... This step follows after the genome of a species has been sequenced. In general, the process includes identifying protein-coding regions, RNA genes, and regulatory regions. The three major categories of gene prediction algorithms are alignment-based, sequence-based, and content-based. Some algorithms ...
... This step follows after the genome of a species has been sequenced. In general, the process includes identifying protein-coding regions, RNA genes, and regulatory regions. The three major categories of gene prediction algorithms are alignment-based, sequence-based, and content-based. Some algorithms ...
Mitochondrial Genome Evolution, Vol 63. Advances in Botanical Research Brochure
... Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to 646-607-1907 (from USA) or +353-1-481-1716 (from Rest of World). If you have any questions please visit http://www.researchandmarkets.com/contact/ ...
... Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to 646-607-1907 (from USA) or +353-1-481-1716 (from Rest of World). If you have any questions please visit http://www.researchandmarkets.com/contact/ ...
What are Math and Computer Science doing in Biology?
... that two random sequences would have that level of similarity or more. We don’t reject the possibility that two sequences are similar due only to chance, unless the computed ...
... that two random sequences would have that level of similarity or more. We don’t reject the possibility that two sequences are similar due only to chance, unless the computed ...
Agrobacterium tumefaciens
... It provides a relatively simple and well understood genetic improvement in which to isolate foreign DNA Its primary genetic complement is contained on a single chromosome which locations and sequences of a large number of its genes are known The genetic code is nearly universal Under the best circum ...
... It provides a relatively simple and well understood genetic improvement in which to isolate foreign DNA Its primary genetic complement is contained on a single chromosome which locations and sequences of a large number of its genes are known The genetic code is nearly universal Under the best circum ...
Book 1.indb
... their classical paper «Teleonomic mechanisms in cellular metabolism, growth, and differentiation» (Monod, Jacob, 1961). To preserve intracellular homeostasis and the adaptive response of the genome to environmental challenges, they emphasized the biological purposefulness or the teleonomy of cell re ...
... their classical paper «Teleonomic mechanisms in cellular metabolism, growth, and differentiation» (Monod, Jacob, 1961). To preserve intracellular homeostasis and the adaptive response of the genome to environmental challenges, they emphasized the biological purposefulness or the teleonomy of cell re ...
2014 Spring Seminar Speaker Series Xuegong Zhang, PhD
... Metagenomes are the mixture of DNAs from all microbial genomes (the microbiome) in samples of environment or human niches. The next-generation sequencing (NGS) technology has made large-scale study of metagenomes feasible, which opens a promising new way for understanding our “other self”: the micro ...
... Metagenomes are the mixture of DNAs from all microbial genomes (the microbiome) in samples of environment or human niches. The next-generation sequencing (NGS) technology has made large-scale study of metagenomes feasible, which opens a promising new way for understanding our “other self”: the micro ...
Homework - The Fenyo Lab
... [The problem with all of these methods is that they are imprecise – some peaks are close to two genes, some are not near any gene, some are in the middle of one and also close to the TSS of another, etc. Associations of a peak with a gene must be VALIDATED in some way.] ...
... [The problem with all of these methods is that they are imprecise – some peaks are close to two genes, some are not near any gene, some are in the middle of one and also close to the TSS of another, etc. Associations of a peak with a gene must be VALIDATED in some way.] ...
Arabidopsis
... the sequencing community should abandon wholegenome-shotgun based approaches. These are the most efficient cost-effective means of capturing the bulk of the euchromatic sequence.” ...
... the sequencing community should abandon wholegenome-shotgun based approaches. These are the most efficient cost-effective means of capturing the bulk of the euchromatic sequence.” ...
Genome browser - Indiana University
... – Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia ) – Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) ...
... – Harmful (diabetes, cancer, heart disease, Huntington's disease, and hemophilia ) – Latent (variations found in coding and regulatory regions, are not harmful on their own, and the change in each gene only becomes apparent under certain conditions e.g. susceptibility to lung cancer) ...
DNA and the Genome - Speyside High School
... 1. Single gene mutations These mutations involve a change in one of the base pairs in the DNA sequence of a single gene. Also known as point mutations. These may occur in the protein-coding sequence or the regulatory sequences which control expression of the gene. CFE Higher Biology ...
... 1. Single gene mutations These mutations involve a change in one of the base pairs in the DNA sequence of a single gene. Also known as point mutations. These may occur in the protein-coding sequence or the regulatory sequences which control expression of the gene. CFE Higher Biology ...
Lecture 1: A first look at a genome (sequence statistics)
... biomedical information - all for the better understanding of molecular processes affecting human health and disease. ...
... biomedical information - all for the better understanding of molecular processes affecting human health and disease. ...
ComPhy User Manual
... All sequence files need to be stored in directory “SeqDir” in “Input” folder. 2. All gene physical location files need to be in “GeneLocDir” in “Input” folder. The location file is in the format of following: Line 1: “genome_size #” shows genome sequence length, can not leave empty Line 2: “gene_num ...
... All sequence files need to be stored in directory “SeqDir” in “Input” folder. 2. All gene physical location files need to be in “GeneLocDir” in “Input” folder. The location file is in the format of following: Line 1: “genome_size #” shows genome sequence length, can not leave empty Line 2: “gene_num ...
Alu elements and splicing events
... stopped in evolution after the emergence of animals (~1,000 MYA). ...
... stopped in evolution after the emergence of animals (~1,000 MYA). ...
Microbes R the Biosphere?
... Can sequencing Nick's DNA solve this mystery? Nick's doctor and other specialists had already tested Nick for a number of genetic mutations that could cause the observed symptoms, and found nothing. Now they wondered if they could sequence Nick's entire genome, quickly enough to save him, at a reas ...
... Can sequencing Nick's DNA solve this mystery? Nick's doctor and other specialists had already tested Nick for a number of genetic mutations that could cause the observed symptoms, and found nothing. Now they wondered if they could sequence Nick's entire genome, quickly enough to save him, at a reas ...
Human Genome Project
The Human Genome Project (HGP) is an international scientific research project with the goal of determining the sequence of chemical base pairs which make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and functional standpoint. It remains the world's largest collaborative biological project. The project was proposed and funded by the US government; planning started in 1984, got underway in 1990, and was declared complete in 2003. A parallel project was conducted outside of government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centers in the United States, the United Kingdom, Japan, France, Germany, and China.The Human Genome Project originally aimed to map the nucleotides contained in a human haploid reference genome (more than three billion). The ""genome"" of any given individual is unique; mapping ""the human genome"" involves sequencing multiple variations of each gene.